For Mike Michna, completing an intense 15-mile bike ride at UPMC Hillman Cancer Center’s annual Rush to Crush Cancer event wasn’t just a physical...

Genomic Health Innovations, Perspectives, and Progress Bloom in the Flower City

A head-to-head double-ring complex of the human multifunctional DNA repair protein RAD52 mediates protection of stalled replication forks during replication stress, protecting them from reversal by SM...

Invasive lobular carcinoma of the breast (ILC) is typically estrogen receptor α (ER)-positive and presents with biomarkers of anti-estrogen sensitive disease, yet patients with ILC face particularly p...

*Single Day registrants receive access to one day of the scientific program. Single Day Registration does not include access to social programs unless these programs occur on the registered day.

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...

The mission of the Women in EMGS (WEMGS) Special Interest Group (SIG) is to provide a forum for discussion on the specific challenges faced by women in our society, a place for EMGS members of any sex interested in this topic to meet and share with one another, and an organized effort to share our experiences and support each other. Women in all fields of science have encountered barriers due to both negative stereotypes leading to being dismissed more easily as scientists, as well as societal pressures to perform more uncompensated and unrecognized work both in the workplace and at home. For both sexes, expectations in science have been at odds with the fulfillment of responsibilities outside of work (e.g. caregiving) and the nurturing of healthy and meaningful human relationships.The main event sponsored by WEMGS is a luncheon at the annual EMGS meeting. This luncheon may feature, for example, an invited speaker or a group discussion. Relevant activities of this SIG may also include, but are not limited to, planning and sponsoring symposia, platform sessions, breakfast meetings, social events, and workshops for the EMGS Annual Meeting, and updating members about the latest news through the EMGS website and email forum. Overall, this SIG provides a platform for members from all sectors (academia, industry, and government agencies) to discuss issues of importance to the WEMGS members and provide support to each other.

Tsao et al. uncover a novel pathway for genotoxicity, termed RNA-damage-induced DNA breaks (RDIBs). The mechanism for preventing RDIBs is orchestrated by YTHDC1 along with the THO complex, which funct...

Most cancers upregulate the telomere lengthening enzyme telomerase to achieve unlimited cell division. How chemotherapeutic nucleoside 6-thio-2’-deoxyguanosine (6-thio-dG) targets telomerase to inhibi...

Pittsburgh's economy once relied heavily on the steel industry, which lined Second Avenue with miles of mills. When that industry collapsed, medicine and education filled the economic void.

The bypass of DNA lesions by translesion synthesis (TLS) polymerases is a critical step for DNA damage tolerance, allowing the completion of DNA synth…

Tabletop Exhibits will be open Sunday, September 7, through Tuesday, September 9. At the exhibits, scientists will have a first-hand opportunity to talk with exhibitors and learn about the products and services they offer.

We advance health and well-being by promoting research and education in biological and biomedical sciences through collaborative advocacy and service to our societies and their members.

The reductions target indirect costs that cover administrative and equipment costs.