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Nima Mosammaparast

@nimamlab.bsky.social
411 followers 109 following 45 posts

Professor of Pathology at WashU, St. Louis, Co-Director DNA Repair Program @Siteman Cancer Center. Father, husband, immigrant.

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Nima Mosammaparast @nimamlab.bsky.social · 13/01/2026
We recently had to say goodbye to Tala, our feisty but beloved grey tabby, at the age of (almost) 18. She had a good life and we will miss her dearly.
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Nima Mosammaparast @nimamlab.bsky.social · 17/12/2025
To top off the end of 2025, a new preprint from our lab! We find an unanticipated new answer to an old question in DNA repair. www.biorxiv.org/cgi/content/...
biorxiv.org
Human MutLa activates methylpurine DNA glycosylase to induce alkylation damage cytotoxicity
Alkylation chemotherapy is commonly used against tumors such as glioblastoma, yet resistance often develops through downregulation of mismatch repair (MMR). Previous work has established that loss of ...
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Nima Mosammaparast @nimamlab.bsky.social · 19/08/2025
A giant will be missed here at WashU. His laboratory was directly above mine. internalmedicine.wustl.edu/obituary-stu...
internalmedicine.wustl.edu
Obituary: Stuart Arthur Kornfeld, MD - John T. Milliken Department of Medicine
October 4, 1936 – August 17, 2025 It is with deep sadness that I share the news that Dr. Stuart Arthur Kornfeld, Professor Emeritus, passed away on Sunday, August 17, 2025, from complications of Parki...
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Reposted by Nima Mosammaparast
Emily Feng @emilyzfeng.bsky.social · 05/06/2025
"I think we have a bias as people coming from the tech industry where we worked at companies, you know, such as Google, Facebook, these companies that have plenty of money, are funded by investors and have lots of people kind of sitting around doing nothing." www.npr.org/2025/06/02/n...
npr.org
Former DOGE engineer says federal waste and fraud were 'relatively nonexistent'
NPR's Juana Summers talks with Sahil Lavingia, who worked for the Department of Government Efficiency as a software engineer assigned to the Department of Veterans Affairs, about his experience.
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Nima Mosammaparast @nimamlab.bsky.social · 20/05/2025
Unbelievable.
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Nima Mosammaparast @nimamlab.bsky.social · 03/04/2025
Yum!!! 😂
theonion.com
Trump Informs Nation They Better Start Liking Those Little Canned Wieners
WASHINGTON—Saying that Americans should anticipate certain lifestyle changes as a result of his newly announced tariffs, President Donald Trump informed the nation Thursday that they better start liki...
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Nima Mosammaparast @nimamlab.bsky.social · 26/03/2025
It was forty years ago today that I came to the US with my family to escape war and repression in Iran. I remain thankful and amazed at where life has led me. #freedom
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Nima Mosammaparast @nimamlab.bsky.social · 09/03/2025
This is why we need science.
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Reposted by Nima Mosammaparast
Hiten Madhani @hitenmadhani.bsky.social · 06/03/2025
Signed. You should too. www.change.org/p/petition-t...
change.org
Sign the Petition
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
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Nima Mosammaparast @nimamlab.bsky.social · 03/03/2025
A great pleasure to share our newest paper out this morning @cp-molcell.bsky.social. We show that damage to nascent RNAs should not be ignored, and under certain conditions, these can turn into DNA breaks. We call this phenomena RDIBs (RNA Damage Induced Breaks). www.cell.com/molecular-ce...
cell.com
YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks
Tsao et al. uncover a novel pathway for genotoxicity, termed RNA-damage-induced DNA breaks (RDIBs). The mechanism for preventing RDIBs is orchestrated by YTHDC1 along with the THO complex, which funct...
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Nima Mosammaparast @nimamlab.bsky.social · 13/02/2025
New recipe for the family: Parmesan risotto with roasted beets and pistachios. #success
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Nima Mosammaparast @nimamlab.bsky.social · 27/01/2025
Anyone else stocking up on #Covfefe?!?
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Nima Mosammaparast @nimamlab.bsky.social · 26/01/2025
Rudolf the white nosed pancake, had a very shiny nose…
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Nima Mosammaparast @nimamlab.bsky.social · 23/01/2025
I am planning to make it through the #NIH freeze with some creative adult beverages. Any suggestions?!?
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Nima Mosammaparast @nimamlab.bsky.social · 14/11/2024
So tonight I'm going to sketch a plan about my next grant using worms as a model system.
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Nima Mosammaparast @nimamlab.bsky.social · 14/11/2024
If it wasn't clear already, I hope my first post here makes it clear what I do and love.
annualreviews.org
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease | Annual Reviews
All cells are exposed to chemicals that can damage their nucleic acids. Cells must protect these polymers because they code for key factors or complexes essential for life. Much of the work on nucleic...
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