Oliver Mueller-Cajar @omc111.bsky.social · 13/07/2026Just came across these on my bookshelf. Nice to share.. 010
Reposted by Oliver Mueller-CajarBen Long @botbml.bsky.social · 23/03/2026Partitioning of Rubisco activase into the pyrenoidal Rubisco condensate is mediated by a functional protein-protein interaction @omc111.bsky.social www.nature.com/articles/s41...nature.comPartitioning of Rubisco activase into the pyrenoidal Rubisco condensate is mediated by a functional protein-protein interaction - Nature CommunicationsAlgal photosynthesis relies on a biomolecular condensate known as the pyrenoid, which sequesters the cell’s Rubisco. The pyrenoid constituent Rubisco activase partitions to the condensate via an eleme... 053
Reposted by Oliver Mueller-CajarAlbert I. Chen @chenlaboratory.us · 10/03/2026So great to catch up with @omc111.bsky.social today and learn about the exciting work his lab is doing to better understand algal pyrenoids and liquid-liquid phase separation. 021
Reposted by Oliver Mueller-CajarMartin Jonikas @mjonikas.bsky.social · 01/02/2026We genetically disconnected starch from the matrix in the algal pyrenoid! A saga1;saga2 double mutant lacks a starch sheath! Our model: SAGA1 & SAGA2 locally initiate starch on the pyrenoid surface by enriching starch precursors. 🌞🦠🔬🔌👀 www.biorxiv.org/content/10.6... 02915
Reposted by Oliver Mueller-CajarJames Barrett @james-r-barrett.bsky.social · 30/01/2026How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵 Preprint here!: www.biorxiv.org/content/10.6... @cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social #Rubisco #PhaseSeparation #Condensates #Pyrenoid 17937
Oliver Mueller-Cajar @omc111.bsky.social · 03/10/2025Sign up for the inaugural Singapore Biosciences Symposium at SBS, NTU. We have an outstanding lineup of speakers at the intersection of plant biology and biomolecular condensates! www.ntu.edu.sg/sbs/symposiu...ntu.edu.sgSBS 2025 061
Reposted by Oliver Mueller-CajarSavage Lab @savagecatsonly.bsky.social · 24/01/2025What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415... 37438
Oliver Mueller-Cajar @omc111.bsky.social · 23/01/2025Noam presents the most state of the art Rubisco search engine.. great to see this out! 150
Oliver Mueller-Cajar @omc111.bsky.social · 04/01/2025Wow, chloroplast base editing leads to faster Rubisco and more biomass in Arabidopsis! www.biorxiv.org/content/10.1...biorxiv.orgChloroplast genome editing of Rubisco boosts photosynthesis and plant growthPhotosynthetic inefficiencies limit the productivity and sustainability of crop production and the resilience of agriculture to future societal and environmental challenges. Ribulose-1,5-bisphosphate ... 061
Reposted by Oliver Mueller-CajarOwen Atkin @owenatkin.bsky.social · 22/11/2024A great way to end the week - catching up with @omc111.bsky.social and Shawn Lum to discuss links between ANU and NTU, and ideas for how to extend thermal tolerance of photosynthesis. @ouranu.bsky.social 121
Reposted by Oliver Mueller-CajarBen Engel @cellarchlab.com · 19/11/2024Beautiful study by Martin, Alistair, and crew on the membrane tubules that traverse the Chlamydomonas pyrenoid and help deliver a high concentration of #CO2 to Rubisco 🧪🌾 0167
Reposted by Oliver Mueller-CajarNature Plants @natplants.nature.com · 04/10/2024New Letter: "Rubisco supplies pyruvate for the 2-C-methyl-d-erythritol-4-phosphate pathway" rdcu.be/dVZMj Rubisco fixes CO2. Its lesser-known side job is supplying pyruvate in the chloroplast, an observation that solves a long-standing paradox of central metabolism. #PlantScience 22312
Reposted by Oliver Mueller-CajarGustaf Degen @gustaf23.bsky.social · 18/11/2024go.bsky.app/ErhhGGU 3117
Reposted by Oliver Mueller-CajarItai Yanai @itaiyanai.bsky.social · 09/11/2024Doing good science is 90% finding a science buddy to constantly talk to about the project. 22877215
Reposted by Oliver Mueller-CajarAlex Holehouse @alexholehouse.bsky.social · 10/11/2024BONUS! If IDPs are your jam, check out an ever-expanding starter pack! go.bsky.app/J23B51L 133019
Reposted by Oliver Mueller-CajarDavid Kuster @rnadavid.bsky.social · 18/11/2024Biomolecular condensate starter pack! Trying to compile & to bring together biomolecular condensate enthusiasts & critics! Please join this non-exhaustive (sorry!) collection & just ping me for addition. #condensates, #phaseseparation, #granules, #IDPs go.bsky.app/NFqmffa 194525
Reposted by Oliver Mueller-CajarChenxin Li, PhD @chenxinli2.bsky.social · 17/11/2024I have a YouTube playlist (10 videos) for #MolecularBiology for my undergrad interns in the lab. www.youtube.com/playlist?lis... I usually have my interns watch these videos to get introduced to the basic concepts before I go show them how to in the lab. 78119
Oliver Mueller-Cajar @omc111.bsky.social · 18/11/2024Nice, would be interesting to see whether RbcL is identical between clones or has diffused in sequence space given massive changes in CO2 concentration since the seed germinated.. 041
Reposted by Oliver Mueller-CajarSeth Abramson @sethabramson.bsky.social · 17/11/2024I learned some stuff about Bluesky I did not know by reading this. Maybe worth passing it on to others so we can all start getting the full benefit of the 🦋.theverge.comHere’s some cool stuff you can do with BlueskyIt’s not just an Alf pics repository. 1540159127541
Reposted by Oliver Mueller-CajarMarc Somssich @somssich.bsky.social · 15/11/2024Yup, the Plant Science Starter Pack has been doing an amazing job. 👌 go.bsky.app/8Zfmwf7 1125
Reposted by Oliver Mueller-CajarMike Haydon 🌱 🌾 🧬 ⏰ @hikemaydon.bsky.social · 15/11/2024Here is a starter to a starter pack for the Aus plant science community. Let’s rebuild. #plantscience Let me know if you want to be added. Help me find more. go.bsky.app/AiLTKHH 84026
Reposted by Oliver Mueller-CajarRazvan Borza @rborza.bsky.social · 17/11/2024⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1: bsky.app/starter-pack... Structural Biology 2: bsky.app/starter-pack... Crystallography: bsky.app/starter-pack... Synchrotron&CryoEM: bsky.app/starter-pack... 39287179
Oliver Mueller-Cajar @omc111.bsky.social · 11/09/2024I have a PhD scholarship available for a student to join my group at NTU Singapore in the January 2025 intake. The student will work on a project related to the cellular biochemistry of the diatom pyrenoid. Here is our first paper on the topic: www.pnas.org/doi/abs/10.1...pnas.orgA linker protein from a red-type pyrenoid phase separates with Rubisco via oligomerizing sticker motifs | PNASThe slow kinetics and poor substrate specificity of the key photosynthetic CO2-fixing enzyme Rubisco have prompted the repeated evolution of Rubisc... 020
Oliver Mueller-Cajar @omc111.bsky.social · 17/01/2024I love the periodic articles about chilly weather in Singapore. Some days we will have to deal with 23 degrees Celsius.. 050
