obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/10/2026Enjoyable day and interesting talks at the @royalmicrosoc.bsky.social AGM on Wednesday. Pleased that there was a peaceful transfer of power @yorkbioimaging.bsky.social 😜 (as an aside, the Royal Society of Chemistry's premises are very nice) 031
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026Also the SBF-SEM imaging captured microgamete entry into the macrogamete, revealing new insights into Plasmodium fertilization. This information is important for the development of potential transmission blocking vaccines to prevent malaria! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026This revealed that the basal body of these cells has a unique arrangement and is unusually short, and that microgametocytes have a deuterosome-like structure that may provide a nucleating platform for the intiial basal body formation, allowing for the very rapid assembly of flagella 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026This study used serial section electron tomography and SBF-SEM to look at gamete formation and structure in the malaria parasite Plasmodium 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026New preprint! Hair et al.- Ultrastructural dynamics of basal bodies during microgamete formation and fertilisation in Plasmodium doi.org/10.64898/202...doi.org 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 11/08/2026Damn straight there's work in progress 000
Reposted by @obcbioimaging.bsky.socialIgnacio Vega-Vásquez @igvegvas.bsky.social · 07/08/2026(1/4) We are very excited to share our latest preprint from @sauer-lab.bsky.social: Mega Expansion Microscopy (Mega-ExM)! We combine iterative hydrogel expansion with whole-proteome NHS labeling and post-expansion immunostaining, reaching tunable expansion factors up to ~1500× in whole cells 🤯 34718
Reposted by @obcbioimaging.bsky.socialRoyal Microscopical Society @royalmicrosoc.bsky.social · 10/08/2026Become an RMS member today! Join our friendly, international community of #microscopy users, keep up with all the latest developments and enjoy a huge range of benefits! 😃🔬 Find out more and join online: ow.ly/GxSN50Wuvsc 011
Reposted by @obcbioimaging.bsky.socialeurobioimaging.bsky.social @eurobioimaging.bsky.social · 28/07/2026#EuroBioImaging's UK Node 🇬🇧 is expanding, from 7 to 13 sites after a successful upgrade application. More technologies, FAIR image analysis support & better geographic coverage ... 👀 check out what the upgraded UK Node has to offer! ⤵️ www.eurobioimaging.eu/news/the-uk-... @bioimaginguk.bsky.social 122
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Importantly, knocking out the KIAP4 protein reduces Leishmania haptomonad adhesion and colonization of the sandfly stomodeal valve. This makes it these proteins an important target for reducing parasite transmission and therefore infection! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Here is a video produced using one of our confocal microscopes of KIAP4 (in green) accumulating as the flagella remodels to form the adhesion plaque! 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026This work identifies the KIAP4 protein, a new component of the Leishmania adhesion complex, which is involved in parasite transmission. KIAP4 is part of a larger gene family that is found in other kinetoplastid parasite species like Trypanosoma congolense 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Very proud of this collaboration authored by former PhD student Barrack Owino, together with colleagues from Charles University Prague and University of Oxford 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Leishmania news! "Identification of a conserved gene family with an essential role in Leishmania parasite–insect vector adhesion" doi.org/10.1073/pnas...doi.orgIdentification of a conserved gene family with an essential role in Leishmania parasite–insect vector adhesion | PNASAdhesion to tissues and surfaces is used by pathogens to avoid clearance, maintain infections, and facilitate transmission. An important example is... 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026The Journal of Cell Science also did a featured interview with first-author Jorge! doi.org/10.1242/jcs.... 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026The Sunter and Wheeler groups used Centre for BioImaging equipment to study the function of the ESB1 gene in the life-cycle of the pathogen Leishmania. ESB1 is located in a specific nuclear body, and it helps control expression of δ-amastins (cell surface glycoproteins important for infection) 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Leishmania news: "Regulation of Leishmania surface coat proteins by the nuclear protein ESB1" doi.org/10.1242/jcs....doi.orgRegulation of Leishmania surface coat proteins by the nuclear protein ESB1Summary: The surface of the Leishmania parasite in the mammalian host is covered by a protein called amastin whose expression is tightly regulated. We show that amastin expression regulation is contro... 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/07/2026onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.com 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/07/2026New review in the Journal of Microscopy: From EM to AI:Multiscale imaging of the secretory pathway with insights from plant cells Charlotte Pain and Emily Farley discuss the history of imaging the ER, from classical EM to fluorescent super-resolution LM, and future possibilities with AI analysis 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026On a personal note, this publication was a long struggle, so a *huge* thank you to colleagues and everyone who gave advice and experimental support, and also to the reviewers and editors that greatly improved the manuscript 🔬🍀🙏 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026Hopefully these findings can inform and stimulate future research into Marchantia meristems and developmental biology, and meristematic regeneration and apical dominance in plants in general! 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026There is also longer-range signalling between apical notches and regenerating regions. It appears that the central tissues can transmit this signal, but peripheral regions cannot. The phytohormone auxin is involved, with a balance between sources and sinks being important 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026It turns out that the apical notch has a substructure, that paracrine signalling appears to be important, and notches can reorientate in response to damage. Outside of the notches there is no clear predictability where meristems regenerate- apart from the oldest (stalk scar) cells not regenerating 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026The liverwort Marchantia makes clonal propagules called gemmae that are very accessible for experimentation and microscopy. This work explores the two (pre-)meristematic "apical notches" of the gemma and how meristem regeneration proceeds if these apical notches are removed or perturbated 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026Laser ablation and confocal microscopy of fluorescent marker lines to reveal more about how meristems and apical dominance operates in Marchantia polymorpha www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 100
Reposted by @obcbioimaging.bsky.socialSainsbury Laboratory Cambridge University (SLCU) @slcuplants.bsky.social · 19/06/2026New insights into cell fates of the Arabidopsis inflorescence meristem @sebamorenor.bsky.social generated the most detailed map to date of this critical stem cell niche, identifying 18 distinct cell type clusters, including precursors to cortex & vascular tissues www.slcu.cam.ac.uk/news/new-ins... 24830
Reposted by @obcbioimaging.bsky.socialPawel Burkhardt @pawelburkhardt.bsky.social · 16/06/2026How ancient are the building blocks of animal sensory systems? Key components of animal sensory systems evolved before animals. We find that choanoflagellates possess diverse & spatially segregated TRP channels, pointing to ancient origins of sensory specialization. doi.org/10.64898/202... 411958
Reposted by @obcbioimaging.bsky.socialRoyal Microscopical Society @royalmicrosoc.bsky.social · 11/06/2026Our June issue of infocus Magazine #RMSinfocus is now freely available to read online! Loads of great content - including a colourful preview of the 21st International Microscopy Congress (#IMC21) coming to Liverpool, UK, this summer! Read the issue: ow.ly/jQgg50Zanmt 053
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 08/06/2026Exciting results from experiments, accepted papers and upgraded microscope systems. Occasionally science gives you a good week, and last week was such a week :) 000
Reposted by @obcbioimaging.bsky.socialFocalPlane @focalplane.bsky.social · 26/05/2026If you missed the first webinar, featuring talks from Thomas Ott @ottlab.bsky.social (on behalf of Beatrice Lace @blace.bsky.social) and Simon Gilroy, you can view the recordings here: focalplane.biologists.com/2026/05/19/f...focalplane.biologists.comFocalPlane features... Thomas Ott and Simon Gilroy - FocalPlaneFocalPlane features... Thomas Ott and Simon Gilroy - News 031
Reposted by @obcbioimaging.bsky.socialFocalPlane @focalplane.bsky.social · 26/05/2026Register now for the 2nd webinar in our new series on quantitative plant imaging, hosted by @ajcellbio.bsky.social & @joemckenna.bsky.social. In this webinar we’ll hear from @laurabacete.bsky.social on Brillouin microscopy & @sventruckenbrodt.bsky.social on expansion microscopy. 🗓️16 July, 15:00 BSTfocalplane.biologists.comRegister for FocalPlane features... quantitative plant imaging across scales - FocalPlaneRegister for FocalPlane features... quantitative plant imaging across scales - News 11110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/05/2026Congratulations to the PhD graduands getting their degrees conferred today- in particular BioImaging users Nadine, Barrack, Alistair, Emily and Grace! 000
Reposted by @obcbioimaging.bsky.socialRoyal Microscopical Society @royalmicrosoc.bsky.social · 12/05/2026We are very pleased to announce Prof. Paul Guichard and Dr. Virginie Hamel @centriolelab.bsky.social as joint winners of the RMS Award for Light Microscopy 🔬 👏 🏅 Huge congratulations to both! Read more about Paul and Virginie's achievements: www.rms.org.uk/resource/pro... 57421
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 30/04/2026Gotta get that Lunapark 1 and 2 balance right if you want proper cisternae in your endoplasmic reticulum! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 30/04/2026Built different: ER cisternae formed by the Arabidopsis Lunapark proteins differ in ultrastructure and affect ER–Golgi transport nph.onlinelibrary.wiley.com/doi/10.1111/...nph.onlinelibrary.wiley.comBuilt different: ER cisternae formed by the Arabidopsis Lunapark proteins differ in ultrastructure and affect ER–Golgi transportThe endoplasmic reticulum (ER) is a key structure in plant cells that helps produce and transport proteins. We discovered that different Lunapark proteins shape ER structures in distinct ways, affect... 111
Reposted by @obcbioimaging.bsky.socialBioImagingUK @bioimaginguk.bsky.social · 13/04/2026🔬 UK researchers - funding is available to access world-class bioimaging facilities! The UK Bioimaging User Access Fund offers up to £5K for bioimaging or £2K for image analysis at 6 UK sites Open to PhD students, postdocs, technicians & PIs 📅 Next deadline: 31 Jul '26 👉https://shorturl.at/M2ckv 095
Reposted by @obcbioimaging.bsky.socialFocalPlane @focalplane.bsky.social · 20/04/2026🔬🔦In their Imaging spotlight, @taylashakespeare.bsky.social and @ijayas.bsky.social highlight their research dissecting receptor sorting in endosomes using the calibrated 3D ExM toolkit that they developed. focalplane.biologists.com/2026/04/15/i...focalplane.biologists.comImaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - FocalPlaneImaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - News 0123
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 31/03/2026Baby shark, doo doo doo doo doo doo (apologies to everyone who now has this song stuck in their head for the rest of the day) 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 18/03/2026(Scientific) Riddles in the Dark 000
Reposted by @obcbioimaging.bsky.socialNew Phytologist @newphyt.bsky.social · 11/03/2026Advances in imaging Arabidopsis embryogenesis Babić et al. @istaresearch.bsky.social @milanzupunski.bsky.social @frimllab.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/... 0148
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 12/03/2026Application deadline is on the 15th of April via the www.msca-agile.eu portal.msca-agile.euMSCA AGILE – Advanced Plant Chromatin & Imaging ResearchMSCA AGILE is a Marie Skłodowska-Curie Doctoral Network advancing plant chromatin research through cutting-edge imaging and computational analysis. 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 12/03/2026PhD Opportunity Alert! The Marie Skłodowska-Curie Actions PhD programme AGILE (Advanced microscopy and image analysis around the plant nucleus) has 15 PhD positions in 6 different countries. This includes one here at Oxford Brookes University with the Kriechbaumer group. 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 03/03/2026Final TEM Rorschachs (for the time being...) 😃😏 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 26/02/2026TEM Rorschach time! First up: fish 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/02/2026On Saturday we Zoomed Into Life at the @obu-hst-research.bsky.social Science Bazaar! Cool things included beetles close up, build-a-cell and a peek at life from the River Thames: featuring a heliozoan, lots of choanoflagellates and a hunting Lacrymaria cilliate 121
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 16/02/2026Showbiz news! Our microscopes will be featured in the new series of CBBC's Operation Ouch, starting with "Awesome Earwax" at 6pm on 23rd February! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 12/02/2026Preparations are underway for the "Zooming into Life" activity stall at the @obu-hst-research.bsky.social 2026 Science Bazaar. Here is a photo from last year, and a sneak preview of one of our samples for this year! 000
