obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/10/2026Enjoyable day and interesting talks at the @royalmicrosoc.bsky.social AGM on Wednesday. Pleased that there was a peaceful transfer of power @yorkbioimaging.bsky.social 😜 (as an aside, the Royal Society of Chemistry's premises are very nice) 031
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026Also the SBF-SEM imaging captured microgamete entry into the macrogamete, revealing new insights into Plasmodium fertilization. This information is important for the development of potential transmission blocking vaccines to prevent malaria! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026This revealed that the basal body of these cells has a unique arrangement and is unusually short, and that microgametocytes have a deuterosome-like structure that may provide a nucleating platform for the intiial basal body formation, allowing for the very rapid assembly of flagella 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 15/09/2026This study used serial section electron tomography and SBF-SEM to look at gamete formation and structure in the malaria parasite Plasmodium 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 11/08/2026Damn straight there's work in progress 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Importantly, knocking out the KIAP4 protein reduces Leishmania haptomonad adhesion and colonization of the sandfly stomodeal valve. This makes it these proteins an important target for reducing parasite transmission and therefore infection! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026Here is a video produced using one of our confocal microscopes of KIAP4 (in green) accumulating as the flagella remodels to form the adhesion plaque! 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026This work identifies the KIAP4 protein, a new component of the Leishmania adhesion complex, which is involved in parasite transmission. KIAP4 is part of a larger gene family that is found in other kinetoplastid parasite species like Trypanosoma congolense 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026The Journal of Cell Science also did a featured interview with first-author Jorge! doi.org/10.1242/jcs.... 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/07/2026The Sunter and Wheeler groups used Centre for BioImaging equipment to study the function of the ESB1 gene in the life-cycle of the pathogen Leishmania. ESB1 is located in a specific nuclear body, and it helps control expression of δ-amastins (cell surface glycoproteins important for infection) 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/07/2026New review in the Journal of Microscopy: From EM to AI:Multiscale imaging of the secretory pathway with insights from plant cells Charlotte Pain and Emily Farley discuss the history of imaging the ER, from classical EM to fluorescent super-resolution LM, and future possibilities with AI analysis 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026There is also longer-range signalling between apical notches and regenerating regions. It appears that the central tissues can transmit this signal, but peripheral regions cannot. The phytohormone auxin is involved, with a balance between sources and sinks being important 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026It turns out that the apical notch has a substructure, that paracrine signalling appears to be important, and notches can reorientate in response to damage. Outside of the notches there is no clear predictability where meristems regenerate- apart from the oldest (stalk scar) cells not regenerating 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/06/2026The liverwort Marchantia makes clonal propagules called gemmae that are very accessible for experimentation and microscopy. This work explores the two (pre-)meristematic "apical notches" of the gemma and how meristem regeneration proceeds if these apical notches are removed or perturbated 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 08/06/2026Exciting results from experiments, accepted papers and upgraded microscope systems. Occasionally science gives you a good week, and last week was such a week :) 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 22/05/2026Congratulations to the PhD graduands getting their degrees conferred today- in particular BioImaging users Nadine, Barrack, Alistair, Emily and Grace! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 31/03/2026Baby shark, doo doo doo doo doo doo (apologies to everyone who now has this song stuck in their head for the rest of the day) 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 18/03/2026(Scientific) Riddles in the Dark 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 12/03/2026PhD Opportunity Alert! The Marie Skłodowska-Curie Actions PhD programme AGILE (Advanced microscopy and image analysis around the plant nucleus) has 15 PhD positions in 6 different countries. This includes one here at Oxford Brookes University with the Kriechbaumer group. 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 03/03/2026Final TEM Rorschachs (for the time being...) 😃😏 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 26/02/2026TEM Rorschach time! First up: fish 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 23/02/2026On Saturday we Zoomed Into Life at the @obu-hst-research.bsky.social Science Bazaar! Cool things included beetles close up, build-a-cell and a peek at life from the River Thames: featuring a heliozoan, lots of choanoflagellates and a hunting Lacrymaria cilliate 121
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 16/02/2026Showbiz news! Our microscopes will be featured in the new series of CBBC's Operation Ouch, starting with "Awesome Earwax" at 6pm on 23rd February! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 12/02/2026Preparations are underway for the "Zooming into Life" activity stall at the @obu-hst-research.bsky.social 2026 Science Bazaar. Here is a photo from last year, and a sneak preview of one of our samples for this year! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 10/02/2026We are very excited that they are trying to revive The Muppet Show 🐸🐷 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 02/02/2026Congratulations to Barrack Owino on passing his PhD viva! Barrack used a range of our LM and EM systems to do his research on Leishmania. We will miss you Barrack; @macleanlab.bsky.social you've gained a gem! 020
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 30/01/2026The lab is a hive of activity today- no wonder the microscopes are booked out so much next week! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 28/01/2026And special congratulations to the winners of the BioImaging Awards! 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 28/01/2026Great to see the breath of research at the Oxford Brookes HST Postgraduate Research Symposium- including wonderful findings made with our microscope systems 🔬🎓🦠 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Finally,congratulations to Carmen Mata Mangas for winning the poster prize 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026The final talk of the day: Mark Johnston of Syngenta on using microscopy in crop protection research 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Sam Caddell from MOA Technology explaining how the GALAXY platform aids novel herbicide discovery and understanding how these new herbicides work 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Nikon's Aki Suto demonstrating the @picoquant.bsky.social FLIM system on our AX NSPARC confocal 020
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Mark Fricker now speaking about quantitative organelle imaging in plants 200
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Secondly, Petra Boevink from The James Hutton Institute on plant pathogens, secreted RXLR effectors and the pitfalls of imaging infected plants 110
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Time for the short talks- first, Joanna Chustecki on imaging the dynamics of plant mitochondria 100
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Larry Griffing of Texas A&M explaining cell autonomous calcium oscillations- the "heartbeat" of plant cells #sparkle ✨️ 010
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Post-lunch, @ajcellbio.bsky.social telling us about imaging plant endocytosis using multiple techniques 🔬 032
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026Now speaking is Ho-Wei Wu of @slcuplants.bsky.social about imaging of circadian gene expression in live growing root tips 063
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026@obcbioimaging.bsky.social 's very own Charlotte Pain telling us about imaging the very dynamic plant endoplasmic reticulum 000
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 07/01/2026First talk at Flora in Focus- Gail Preston @gmpreston.bsky.social of University of Oxford, speaking about metal hyperaccumulation and plant pathogen protection 121
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 05/01/2026Not just flurries of snow in Oxford- flurries of activity as we set up for Flora in Focus: A Microscopy Conference for Plant Scientists 011
obcbioimaging.bsky.social @obcbioimaging.bsky.social · 19/12/2025Christmas- the time of year you get out the fancy stuff 🔬💎 (The History of Science Museum in Oxford has some nice blingy things) 000
