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Netherlands Cancer Institute

@nkinl.bsky.social
3.3K followers 288 following 168 posts

The Netherlands Cancer Institute (NKI): at the international forefront of cancer research and treatment for over 100 years.

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Reposted by Netherlands Cancer Institute
Cancer Grand Challenges @cancergrand.bsky.social · 07/10/2026
A school trip sparked Reuven Agami's curiosity about science 🔬 Today, he's leading team ILLUMINE as they take on the dark proteome challenge. Read the interview at bit.ly/4ytG5Nx @nkinl.bsky.social
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Reposted by Netherlands Cancer Institute
ACIR @acir-org.bsky.social · 07/10/2026
Messemaker and Kwee et al. developed a TCR rapid assembly platform (T-RAP) that could be used to evaluate TCR reactivity acir.org/weekly-dige... @schumacher-lab.bsky.social @nkinl.bsky.social
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Reposted by Netherlands Cancer Institute
Waggoner Lab @labwaggoner.bsky.social · 02/10/2026
Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction @cp-immunity.bsky.social www.cell.com/immunity/ful... @schumacher-lab.bsky.social @nkinl.bsky.social
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Netherlands Cancer Institute @nkinl.bsky.social · 01/10/2026
Do you want to help map the dark proteome? This is your chance. Join @agamilab.bsky.social, or one of the partner institutes of the ORFeus network, a Horizon Europe program studying the #DarkProteome. Recruitment is open for 15 PhD’s! www.orfeus-dn.eu/apply/ #PhDPositions #CancerResearch #ORFeus
orfeus-dn.eu
Apply to ORFeus — 15 fully funded PhD positions
15 fully funded PhD positions across Europe, starting 2027. Applications open 1 October and close 22 October 2026. Rank up to three projects.
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Reposted by Netherlands Cancer Institute
Bas van Steensel lab (NKI) @basvansteensellab.bsky.social · 18/08/2026
Inferring transcription factor activity: use ATAC-seq, reporter assays, or both? link.springer.com/article/10.1...
link.springer.com
Systematic comparison of estimates of transcription factor activity by ATAC-seq and multiplexed reporter assays - Molecular Systems Biology
Transcription factors (TFs) are central to gene regulation and play critical roles in development, cellular homeostasis and disease. The ability to accurately measure TF activity is essential to under...
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Netherlands Cancer Institute @nkinl.bsky.social · 12/08/2026
Thanks to the Dutch Cancer Society (KWF) 6 new research projects can get started. Four of the 6 projects are supported through proceeds from Alpe d'HuZes. From mechanisms of PARP inhibitor resistance and telomere instability to immunosuppression, stress and immunotherapy response and more:
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Netherlands Cancer Institute @nkinl.bsky.social · 28/07/2026
🎉Congratulations to Fraser Johnson on receiving an NWO Veni grant! Fraser will develop new tools to identify tumor-reactive T cells in melanoma, helping to reveal why some anti-tumor immune responses succeed while others fail.
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Netherlands Cancer Institute @nkinl.bsky.social · 24/07/2026
We are grateful to KWF Dutch Cancer Society for awarding €1.37M to Remond Fijneman and his team for the DIDACTIC study. By combining ctDNA with tumor characteristics, they will investigate whether chemotherapy can be safely omitted for low-risk stage III colon cancer. #PrecisionOncology
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Netherlands Cancer Institute @nkinl.bsky.social · 17/07/2026
Have you previously worked at the NKI? Join our LinkedIn alumni group. A place to reconnect with former colleagues, expand your professional network and stay involved with the NKI community: linkedin.com/groups/1842007/ Feel free to share this post with former NKI colleagues!
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Netherlands Cancer Institute @nkinl.bsky.social · 14/07/2026
"Like pollen carried by bees" - so true. Thanks @eu-life.bsky.social for making this valuable exchange happen.
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Netherlands Cancer Institute @nkinl.bsky.social · 13/07/2026
Will you be our next junior group leader? Check out how Natalie Scholes, Gordie Watt and @woutoosterheert.bsky.social experience starting their groups at the Netherlands Cancer Institute. Apply before August: www.nki.nl/news-events/... #Vacancy #JuniorPI #ResearchOpportunity #NKI #EarlyDetection
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Netherlands Cancer Institute @nkinl.bsky.social · 09/07/2026
🏅Congratulations to René Bernards, who has received China’s highest award for foreign experts in science and technology cooperation. A wonderful recognition of a long-standing international collaboration to move cancer research forward.
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Netherlands Cancer Institute @nkinl.bsky.social · 09/07/2026
On Be Open About Animal Research Day researchers from leading Dutch research institutes are speaking out in support of openness about animal research. They explain why a combination of this research and animal-free methods remains necessary. www.stichtinginformatiedierproeven.nl/researchers-...
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Netherlands Cancer Institute @nkinl.bsky.social · 08/07/2026
In June, several NKI PhD candidates defended their theses, covering gene regulation, immunotherapy, shared decision-making and support for young adults with cancer. Congratulations to Danielle, Chantal, Song and Milou. #CancerResearch #PhDDefense
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Netherlands Cancer Institute @nkinl.bsky.social · 07/07/2026
New in The Lancet Oncology: the phase III SUBITO trial prospectively validates HRD-targeted treatment in stage III HER2-negative breast cancer. Comparable survival, substantially lower toxicity, and no added benefit from intensified chemotherapy. 🔗 doi.org/10.1016/S147...
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Netherlands Cancer Institute @nkinl.bsky.social · 03/07/2026
How does BRCA1-related breast cancer begin? With support from the Gray Foundation, NKI teams led by Hendrik Messal and @josjonkers.bsky.social will study the earliest cellular, genetic and immune changes that allow abnormal cells to survive and expand #BRCA1 #BreastCancer #CancerResearch
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Netherlands Cancer Institute @nkinl.bsky.social · 01/07/2026
We are looking for a Junior Group Leader in Early Cancer Detection: an innovative scientist ready to build an independent research group and bring new ideas to one of our key research themes. Apply: www.nki.nl/news-events/... #tenure #vacancy #juniorPI #faculty #NKI
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Netherlands Cancer Institute @nkinl.bsky.social · 01/07/2026
@leilaakkari.bsky.social @oncodeinstitute.bsky.social @embo.org
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Netherlands Cancer Institute @nkinl.bsky.social · 30/06/2026
🎉 Congratulations to Leila Akkari, who has been elected as an EMBO Member. A wonderful recognition of her research excellence, scientific leadership, and the inspired team behind her work on the tumor microenvironment in cancer. #EMBOMembers2026
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Netherlands Cancer Institute @nkinl.bsky.social · 25/06/2026
Breakthroughs don’t happen by following the obvious path. They begin with people who dare to ask new questions. Who connect ideas others might not see. Who bring science, imagination and ambition together. At the NKI, these inspired minds move research forward. Where science meets inspired minds.
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Netherlands Cancer Institute @nkinl.bsky.social · 18/06/2026
New in The Lancet Oncology: NKI researchers present ARTIMES, an AI model for pleural mesothelioma that measures full tumor volume on CT scans and outperforms physicians and RECIST criteria in treatment response assessment. 🔗 doi.org/10.1016/S147...
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Netherlands Cancer Institute @nkinl.bsky.social · 11/06/2026
New PRECISION consortium research maps early DNA changes in DCIS, pointing to SHOREs and ecDNA as possible signs of more aggressive evolution. Read in Nature Communications: www.nature.com/articles/s41...
nature.com
High-depth whole genome sequencing of premalignant breast lesions reveals rearrangement hotspots and personalized management opportunities - Nature Communications
Predicting progression from ductal carcinoma in situ (DCIS) to invasive breast cancer remains challenging. Here, deep whole genome sequencing of DCIS samples highlights possibilities for personalized ...
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Reposted by Netherlands Cancer Institute
EU-LIFE @eu-life.bsky.social · 04/06/2026
What happens when the EU-LIFE community comes together in one place? Last week in Amsterdam, we exchanged ideas, explored collaboration opportunities and aligned on key issues shaping European research. Thank you to @nkinl.bsky.social for the warm hospitality! Read more ➡️ bit.ly/4x9Xgnk
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Netherlands Cancer Institute @nkinl.bsky.social · 01/06/2026
Couldn't agree more!
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Netherlands Cancer Institute @nkinl.bsky.social · 29/05/2026
Happy to have you here!
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Netherlands Cancer Institute @nkinl.bsky.social · 28/05/2026
Happy to be hosting this year’s meeting! Great to see everyone here in Amsterdam
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Reposted by Netherlands Cancer Institute
EU-LIFE @eu-life.bsky.social · 27/05/2026
📍 The #EULIFE2026 Community Meeting is underway in Amsterdam! Hosted by @nkinl.bsky.social, we kicked off with welcomes from Thijn Brummelkamp and updates from EU-LIFE Chair Marta Miączyńska & Executive Director Marta Agostinho. Looking forward to inspiring exchanges!
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Netherlands Cancer Institute @nkinl.bsky.social · 27/05/2026
Happy and proud to host this year’s meeting!
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Reposted by Netherlands Cancer Institute
Cancer Core Europe @cancercoreeurope.bsky.social · 26/05/2026
We’re proud to join #EWAC2026 — a week of action against cancer across Europe. At #CCE, we advance prevention & early detection through collaboration, innovation, and data-driven precision prevention. @gustaveroussy.fr @vhio.bsky.social @nkinl.bsky.social @nct-heidelberg.bsky.social
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Reposted by Netherlands Cancer Institute
Rik Lindeboom @riklindeboom.bsky.social · 20/05/2026
I’m hiring a Research Technician and a Computational Postdoc! 💻 Computational Postdoc to model context-dependent protein interactions: open until 15th of June: www.werkenbijavl.nl/vacatures/co... 🔬 Technician: open until 3rd of June: www.werkenbijavl.nl/vacatures/re... Please share! #ScienceJobs
werkenbijavl.nl
Computational Postdoc | Werken bij AVL
Computational postdoc in the Lindeboom lab to study context-dependent protein interactions The Lindeboom lab is looking for a talented and motivated ERC-funded computational postdoc who is interested...
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Netherlands Cancer Institute @nkinl.bsky.social · 22/05/2026
Powerful tools are uncovering the “control knobs” of the genome; accelerating how we identify regulatory DNA and even opening the door to rewriting gene expression. Great to see this momentum in the field, including the work of @basvansteensellab.bsky.social 🔗 www.nature.com/articles/d41...
nature.com
These powerful tools reveal the ‘control knobs’ of the genome
By accelerating the identification of DNA sequences that control gene expression, assays are revealing the hidden grammar of the regulatory genome — and giving scientists the means to rewrite it.
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Netherlands Cancer Institute @nkinl.bsky.social · 13/05/2026
Congratulations to all scientists who were selected for a synergy grant by @oncodeinstitute.bsky.social! Scientific collaboration is more important than ever, so we are looking forward to seeing our talented researchers start their new collaborations.
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Netherlands Cancer Institute @nkinl.bsky.social · 07/05/2026
🎉 Congratulations to Michiel Vermeulen @michielvermeulen.bsky.social on his election to the Royal Netherlands Academy of Arts and Sciences @knaw-nl.bsky.social His pioneering work on epigenetic regulation is advancing our understanding of cancer and informing new therapeutic strategies.
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Netherlands Cancer Institute @nkinl.bsky.social · 29/04/2026
🎓 Thanks to new treatments like immunotherapy, patients have better outcomes and live longer. That, argues PhD candidate Mees Egeler, makes it even more important to focus on their quality of life.
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Netherlands Cancer Institute @nkinl.bsky.social · 29/04/2026
🎧 New podcast out!! Daniel Peeper talks functional oncogenomics and cancer research on The Immunology Podcast. Listen here ➡️ www.immunologypodcast.com/ep-126-funct... #CancerResearch #Oncogenomics
immunologypodcast.com
Ep. 126: “Functional Oncogenomics” Featuring Dr. Daniel Peeper - The I…
Dr. Daniel Peeper is a Professor in Functional Oncogenomics at VU University Amsterdam, heading the Department of Molecular Oncology & Immunology and chairing the Research Fac…
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Netherlands Cancer Institute @nkinl.bsky.social · 28/04/2026
Congratulations to Rik Lindeboom on receiving the 2026 NVBMB Prize 🎉 The jury unanimously recognized Rik as a rising star in biochemistry & molecular biology, praising seminal contributions, bold high-impact research, exceptional productivity, and a strong commitment to open tools for the community
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Netherlands Cancer Institute @nkinl.bsky.social · 24/04/2026
Our researchers are exploring whether radiotherapy for soft tissue sarcoma can be delivered in a shorter, less burdensome way without compromising outcomes. The SCOPES studies mark an exciting step forward in rethinking long‑standing treatment standards. Read more ➡️ www.nki.nl/news-events/...
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Netherlands Cancer Institute @nkinl.bsky.social · 23/04/2026
🌷 Junior PI Hendrik Messal: "Stepping into a group leader role at the NKI has been both busy and gratifying, in a place where disciplines, technologies, and people converge with a shared sense of purpose. [...]" Want to join Hendrik and others as a junoir PI? Apply now: www.nki.nl/news-events/...
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Netherlands Cancer Institute @nkinl.bsky.social · 20/04/2026
Out today in Journal of the National Cancer Institute Jonathan Spoor and colleagues show that women who have had a breast reconstruction with silicone implants as part of breast cancer treatment do not face an increased risk of developing autoimmune or rheumatic diseases 🔗 doi.org/10.1093/jnci...
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Netherlands Cancer Institute @nkinl.bsky.social · 15/04/2026
The largest published prospective evaluation of off-label targeted cancer therapies is out today in Nature. Results from the Dutch multicenter DRUP trial show both the potential of this approach and the need for systematic evaluation in clinical trial settings ➡️ www.nature.com/articles/s41...
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Reposted by Netherlands Cancer Institute
Elzo de Wit lab @ NKI @dewitlab.bsky.social · 15/04/2026
New paper in Genes & Dev: we dissected how Sox2 — a key pluripotency TF — is regulated by a distal enhancer cluster (SCR) 100 kb away. The results challenge simple models of cohesin-mediated loop extrusion of gene regulation. genesdev.cshlp.org/content/earl... 🧵
genesdev.cshlp.org
Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to Sox2 looping with its distal enhancer
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
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Netherlands Cancer Institute @nkinl.bsky.social · 15/04/2026
Congrats to Stefano Trebeschi on receiving an NWO Science-XS grant. His project develops symmetry-based AI to detect bone metastases on scans, with the potential to improve treatment evaluation and patient care. More: 🔗 www.nwo.nl/en/news/56-g...
nwo.nl
56 grants for the Open Competition Domain Science-XS package 26-1 | NWO
The topics of the awarded proposals range from identifying the cause of synaptic dysfunction involved in neurological conditions such as Alzheimer’s disease, or exploring Nanopore sequencing of patien...
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Netherlands Cancer Institute @nkinl.bsky.social · 14/04/2026
We’re proud to share that our colleague @myriamchalabi.bsky.social has won the Grand Prize of the 2026 Takeda Innovators in Science Award 🏆 Her bold research in neoadjuvant immunotherapy is reshaping treatment. Congratulations Myriam! 🎥 Watch the video here: www.youtube.com/watch?v=ch_Z...
youtube.com
Innovators in Science Award: 2026 Grand Prize Winner Myriam Chalabi
YouTube video by Takeda
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Netherlands Cancer Institute @nkinl.bsky.social · 09/04/2026
Time to stretch our legs and enjoy the beautiful tulip fields surrounding the venue 🌷
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Netherlands Cancer Institute @nkinl.bsky.social · 09/04/2026
Of course there is also time for food and enjoying the nice Dutch spring sun ☀️
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Netherlands Cancer Institute @nkinl.bsky.social · 09/04/2026
Our junior PI's are presenting their new work and collaboration options for future studies
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Netherlands Cancer Institute @nkinl.bsky.social · 09/04/2026
Today we are at the 2-day NKI retreat full of inspiration and connection
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Netherlands Cancer Institute @nkinl.bsky.social · 07/04/2026
Macrophages play a dubious role in our body. PhD candidate Daniel Taranto found a way to prevent them from helping liver tumor cells grow in the lab. He’s still happy that his PI convinced him to persevere on his journey towards a PhD ➡️ www.nki.nl/news-events/...
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Netherlands Cancer Institute @nkinl.bsky.social · 01/04/2026
@nunopadrao.bsky.social
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Netherlands Cancer Institute @nkinl.bsky.social · 01/04/2026
@tinekelenstra.bsky.social
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