Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' s....

Tenovus Scotland provides vital funds for early stage medical research in Scotland. One of Scotland’s leading medical research charities, it supports pilot projects and new research talent across Scot...

Fourwaves - 5th Transatlantic ECI GPCR Symposium

From fabricated research to paid authorships and citations, organized scientific fraud is on the rise, according to a new Northwestern University study.

Dopaminergic signaling is essential for regulating movement, learning, and reward. Disruptions in this system are linked to neuropsychiatric disorders such as ADHD. ADGRL3, an adhesion G protein-coupl...

Why isn't Br-LSD psychedelic?

What does dopamine actually do? A neuroscientist breaks down the science and clears up common misconceptions.

Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex netwo...

Nature - An algorithm called time–magnitude reinforcement learning (TMRL) extends distributional reinforcement learning to take account of reward time and magnitude, and behavioural and...

While university officials said they’ve still not received official word of such action, they acknowledged receiving about 100 stop-work orders from the federal government on roughly 100 fede…

The US government has begun slashing US$400 million in research grants at Columbia University over pro-Palestinian campus protests.

The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.

Most adhesion GPCRs undergo autoproteolytic cleavage during receptor biosynthesis, resulting in non-covalently bound N- and C-terminal fragments (NTF and CTF) that remain associated during receptor tr...

A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.