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Matthew Williams

@mp-williams.bsky.social
217 followers 103 following 14 posts

Archaeogeneticist by day and night. Postdoc in the Huber Lab at Penn State. Lover of the ancient Near East, philosophy, and coffee.

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Reposted by Matthew Williams
Tom Booth @boothicus.bsky.social · 11/12/2025
🏺 Detailed preprint on the genetics of early farming (TRB-Funnelbeaker associated) and persistent hunter-fisher-gatherer (Pitted Ware-associated) communities on Gotland. Discusses patterns of genetic relatives in both groups, admixture between the groups... www.biorxiv.org/content/10.6...
biorxiv.org
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Matthew Williams @mp-williams.bsky.social · 09/12/2025
For anyone interested in the intersection of genetics, ancestry, evolution, and societal structures this week's workshop will be a treat! Featuring @evoroseman.bsky.social
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UCL Institute of Archaeology @uclarchaeology.bsky.social · 20/11/2025
A belated welcome to @boothicus.bsky.social Dr Tom Booth See & hear Tom on "Who Are Our Ancestors and Why Does It Matter? – A Question of Science with Brian Cox 📺 bit.ly/4i840uW 🎧 bit.ly/49tS70j 📲 profiles.ucl.ac.uk/104583-tom-b... 📸 Michael Bowles | The Francis Crick Institute @crick.ac.uk
Dr Tom Booth, last human on the right on the "Who Are Our Ancestors And Why Does It Matter?" panel
Michael Bowles | The Francis Crick Institute
Dr Tom Booth, on the right on the "Who Are Our Ancestors And Why Does It Matter?" panel
Michael Bowles | The Francis Crick Institute
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Anders Bergström @anders-bergstrom.bsky.social · 17/10/2025
A PhD project in human genomics with me is open for applications through the @nrpdtp.bsky.social. Use biobank-scale genomics datasets to answer long-standing questions about the evolution of our species: biodtp.norwichresearchpark.ac.uk/projects/the...
biodtp.norwichresearchpark.ac.uk
The genomics of modern human biological uniqueness (BERGSTROM_U26DTP) | Doctoral Training Partnership
Modern humans are unique as a species, having spread widely and transformed the world with technology and large-scale societies. But until relatively recently (~50,000 years ago)…
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Tom Booth @boothicus.bsky.social · 19/11/2025
For anyone interested in ancient diseases (either historical or prehistoric) here's an excellent, readable, comprehensive summary of where we are with ancient pathogen DNA. www.nature.com/articles/s41...
nature.com
Insights into infectious diseases through ancient pathogen genomics - Nature Reviews Microbiology
In this Review, Kocher, Krause and Spyrou explore how ancient pathogen genomics is providing new perspectives on the history and evolution of infectious agents. They show how ancient DNA has revealed ...
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Mike Inouye @mikeinouye.bsky.social · 16/11/2025
Hard missing the old twitter days. It’s a bit icky that a lot of interactions amongst academics now happens on linkedin… eventhough bluesky could absolutely be the twitter of old, people just aren’t engaging like they used to. Hope it changes…
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Dr Matt Pope @mattpope.bsky.social · 17/11/2025
Interested studying human evolution at @ucl.ac.uk with a dedicated MSc in palaeolithic archaeology, palaeoanthropology, Ice Age fauna, isotopes, aDNA, ancient environments & more? Get in touch for a chat or even a tour of the department with me. @uclarchaeology.bsky.social #PaPa 🏺🦣🧪
Picture of 6 postgrad students sat at a table in a lab studying bones. Text says: The UCL Palaeoanthropology and Palaeolithic (PaPa) MSc programme is an established, pioneering course in human origins delivered by a world-leading university. It will bring you a deep and expert understanding of the scientific record of human evolution which powerfully combines opportunities for the study of palaeolithic archaeology, palaeoanthropology and wider scientific approaches to the early human story.
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Anders Bergström @anders-bergstrom.bsky.social · 17/11/2025
A PhD project on historical genomics in the declining red squirrel in Britain is available in my group, through the @aries-dtp.bsky.social. Use historical genomes to track the effects of decline and genetic rescue in this charismatic species. aries-dtp.ac.uk/studentships...
aries-dtp.ac.uk
Historical genomics of the declining red squirrel in Britain | Aries
Dr Anders Bergström, School of Biological Sciences, University of East Anglia Professor Cock van Oosterhout, School of Environmental Sciences, University of East Anglia Dr Selina Brace…
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Tom Booth @boothicus.bsky.social · 10/11/2025
This is out now: www.sciencedirect.com/science/arti... Association between lactase persistence and height in the past (indicating people with the persistence allele were better nourished by drinking milk than those without it) provides a potential explanation for why it was under strong selection.
sciencedirect.com
Effects of ancestry, agriculture, and lactase persistence on the stature of prehistoric Europeans
Ancient DNA has revolutionized our understanding of human evolutionary history, but studies focusing solely on genetic variation tell an incomplete st…
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Matthew Williams @mp-williams.bsky.social · 06/11/2025
I’m really excited to be hosting @evoroseman.bsky.social for a 1 hour online workshop for the Biomolecular Humanities group on December 10th (8am to 9am PST : 11am to 12pm EST : 5pm to 6pm CET) on the intersection of evolutionary theory, demography and race/ancestry!
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Center for Academic Research & Training in Anthropogeny (CARTA) @anthropogeny.org · 29/08/2025
Don't miss Ancient DNA: New Revelations, a free, public CARTA symposium! 🧬💡 Friday, November 7, 2025 1:00–5:30 PM (Pacific) In-person at the Salk Institute & Live Webcast For more details and registration, visit: carta.anthropogeny.org #carta #cartaucsd #ancientdna
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Tom Booth @boothicus.bsky.social · 26/08/2025
🏺 Useful paper from @mp-williams.bsky.social and co. showing different modelling of the spread of Neolithic farming across Europe. Explores different rates and mechanisms of cultural transmission and suggests as migrants with origins in Anatolia moved across… www.nature.com/articles/s41...
nature.com
Modeling the European Neolithic expansion suggests predominant within-group mating and limited cultural transmission - Nature Communications
The Neolithic Revolution marked an important shift from foraging to farming in human society. Here, the authors show that in Europe the spread of farming involved mostly within-group mating and limite...
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Rosi Fregel @rfregel.bsky.social · 21/08/2025
The AADR Visualizer: An ArcGIS Online Visualizer for ancient human DNA from the Allen Ancient DNA Resource academic.oup.com/bioinformati...
academic.oup.com
The AADR Visualizer: An ArcGIS Online Visualizer for ancient human DNA from the Allen Ancient DNA Resource
AbstractMotivation. The AADR Visualizer is designed to be a public, user-friendly, web-based graphical user interface for visualizing and filtering ancient
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HAAM-community @haam-community.bsky.social · 26/08/2025
🏛️ Still unsure how to spend your afternoon in Turin 🇮🇹 before @isba11.bsky.social starts, come to our #HAAMmeeting @Complesso Aldo Moro and meet young & inspiring researchers! 💻 If you're not in Turin, you can join us online, too. 📖 DM us! #aDNA #HAAMcommunity @isbarchaeology.bsky.social
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Detlef Gronenborn @dgron.bsky.social · 15/08/2025
It's out! 😀 THE MAP: EXPANSION OF FARMING IN WESTERN EURASIA, 9600-4000 BCE 2025.1 Regional updates, particularly 🇺🇦. Colour and greyscale resolutions, and much asked for colour code and legend. @barbarahorejs.bsky.social @leizarchaeology.bsky.social @oeai.bsky.social zenodo.org/records/1688...
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Stacey Ogden 🦔 @labogden.bsky.social · 11/08/2025
NIH is accepting comments about limiting research publication costs. 1. Disallow pub costs, 2. $2K limit, 3. $3K if reviewers are compensated, 4. 0.8% of award (so $250K grant can pay $2K/year on pubs), 5. $6K limit on pub + limit on % of grant spent on pub costs. 🧪 grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH
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Stephen Hill @srhastraea.bsky.social · 09/08/2025
This is a great read - it nails a whole bunch of ways in which LLMs simply don’t ‘think’, let alone at a ‘PhD level’.
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Harald Ringbauer @hringbauer.bsky.social · 07/08/2025
Our aDNA time transect centered on modern Georgia is out! 🧬 Genetic continuity over 5000 years, but some Bronze Age gene flow and urban outliers since Antiquity - including some with artificially deformed skulls 💀 linked by IBD segments to Asian nomads. #aDNA #PopGen www.cell.com/cell/fulltex...
cell.com
The genetic history of the Southern Caucasus from the Bronze Age to the Early Middle Ages: 5,000 years of genetic continuity despite high mobility
Ancient DNA from the Southern Caucasus reveals remarkable genetic continuity, with some mixing from Anatolia/Iran and the Eurasian Steppe, and shows that even periods of urbanization and increased mob...
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Joe Bak-Coleman @jbakcoleman.bsky.social · 06/08/2025
But perhaps most critically, it’s (imo) irresponsible to attribute this to *science* as a whole; suggesting it’s a monolith when things like the image duplication retractions are pretty limited to a unique corner of science under sleuth spotlights.
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Ryan Gutenkunst @ryangutenkunst.bsky.social · 05/08/2025
If you're new to demographic history inference from population genomics, try this webapp I created to illustrate how dadi fits bottleneck models to site frequency spectra: ryangutenkunst-dadi-two-epoch.hf.space . It even outputs files for submitting to the GHIST competition! ghi.st
Logo for the Genomic History Inference Strategies Tournament.
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Hannah Moots @mootspoints.bsky.social · 05/08/2025
🧬🏺Calling everyone interested in the intersection of archaeological theory and ancient DNA! Thrilled to be co-organizing a session for #TRAC2025 with @ezgimou.bsky.social The virtual conference will be held October 22 - 24 and the call for abstracts is now open. Come join us!
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Ezgi Altınışık @ezgimou.bsky.social · 05/08/2025
TRAC 2025 will be held from 22nd to 24th October 2025 in an online format via the Gather Town platform. Here is the link for further info: www.trac.org.uk/upcoming-con...
trac.org.uk
Upcoming Conferences
TRAC 2025 The 33rd Theoretical Roman Archaeology ConferenceWe are pleased to announce that TRAC 2025 conference will be held between 22nd and 24th October 2025 in an online format through the Gathe…
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Ezgi Altınışık @ezgimou.bsky.social · 05/08/2025
🧪 🏺 Excited to co-organize a session with @mootspoints.bsky.social at #TRAC2025! 🧬 Integrating Ancient DNA with Archaeological Theory and Practice We welcome papers on mobility, migration, & identity in the Roman world and beyond. 📢 Call for abstracts now open! Please spread the word. #aDNA #science
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Pontus Skoglund @pontus-skoglund.bsky.social · 01/08/2025
New postdoc opening in our lab: crick.wd3.myworkdayjobs.com/External/job... Don't hesitate to send in your details or contact me if interested!
crick.wd3.myworkdayjobs.com
Postdoctoral Fellow - P Skoglund Lab
Salary for this Role: Salary: From £45,500 per annum with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - P Skoglund Lab Reports to: Pontus Skoglund Closing Date: 20/Aug/2...
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Skyler Berardi @skylerberardi.bsky.social · 31/07/2025
Check out our paper in Evolution Letters! We used D. melanogaster pigmentation as a focal trait to explore parallelism in phenotypic and genomic responses to environmental change - read more at the link below 👇
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Evolution Letters @evolletters.bsky.social · 31/07/2025
How predictably does complex trait adaptation proceed over space and time in wild populations? doi.org/10.1093/evle... Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al. 📷: Dr. Rush Dhillon
Figure showing the experimental overview as a graphic. Remaining alt text taken from the figure caption in the paper: (A) we sampled flies from six wild orchard populations ranging from Homestead, FL, to Lancaster, MA, and established isofemale lines in the laboratory. (B) We returned to a focal orchard in Media, PA, at early- and late-season timepoints and collected flies to capture evolutionary patterns following winter and summer conditions. (C) We then seeded outdoor mesocosms (N = 9) with an outbred population originating from early-season collections in Media, PA, and sampled flies at the end of summer (mid-season) and fall (late-season) to determine if seasonal patterns are recapitulated in experimental populations controlled for migration, drift, and cryptic population structure. (D) Across each wild or experimental context, we sampled flies, established lines in the lab, completed common garden treatment to remove environmental effects, and scored females for abdominal pigmentation. We also conducted pooled DNA sequencing on additional flies sampled from each population to map genomic patterns for candidate pigmentation SNPs.
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Eugenia D'Atanasio @eugeniadat.bsky.social · 26/07/2025
🚨 New paper out in Genome Biology and Evolution! We present new ancient DNA evidence from Central Italy suggesting that Eastern Mediterranean genetic influence predates the Roman Empire. @beniamino77.bsky.social @fravasini.bsky.social 🧵👇 🔗 doi.org/10.1093/gbe/... 1/
doi.org
A new perspective on the arrival of the Eastern Mediterranean genetic influx in Central Italy before the onset of the Roman Empire
Abstract. Italian genetic history was profoundly shaped by the Romans. While the Iron Age Central Italian gene pool was comparable to that of other coeval
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Marco Capodiferro @marcocapo.bsky.social · 24/07/2025
Turns out imputation of introgressed archaic regions in aDNA works really well — sometimes even better than for the rest of the genome. More on this (and other cool results) in our new preprint 👇 #aDNA #ArchaicIntrogression #imputation doi.org/10.1101/2025...
doi.org
Archaic ancestry inference in imputed ancient human genomes
When modern humans expanded from Africa into Eurasia, they interbred with archaic hominins such as Neanderthals and Denisovans. This groundbreaking discovery, made in part possible through the genomic...
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Yun S. Song @yun-s-song.bsky.social · 06/06/2025
The 2026 Probabilistic Modeling in Genomics (ProbGen) meeting will be held at UC Berkeley, March 25-28, 2026. We have an amazing list of keynote speakers and session chairs: probgen2026.github.io Please help spread the news.
probgen2026.github.io
Home - ProbGen 2026
Your Site Description
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EvolDir @evoldir.bsky.social · 24/07/2025
The Mathieson Lab at the University of Pennsylvania is hiring a computational postdoc in machine learning and evolutionary biology. Apply with a CV and references: smathi@sas.upenn.edu. More info: saramathieson.github.io/lab #postdoc
saramathieson.github.io
We are a computational lab focusing on developing machine learning algorithms for biological data. Currently we are working on inference tasks related to natural selection and demographic inference, as well as generative models for genomic data from humans, mosquitos, and other species.
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Hannah Moots @mootspoints.bsky.social · 22/07/2025
Come check out my poster this afternoon! On the language we use to talk mobility in ancient DNA studies #SMBE2025
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Hanbin Lee @epigenci.bsky.social · 20/07/2025
Hence, this highlights the fundamental difference btw genomic and family h2. The former is considering millions of years of mutation while the latter is looking at everything but mutations over a very short period of time.
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Hanbin Lee @epigenci.bsky.social · 20/07/2025
I can now finally speak out loud my honest thoughts on missing heritability or the genomics/family gap in h2 estimates. Based on new paper the *issue* is a feature and not a bug. TLDR: SNP h2 only captures mutational variance and family h2 captures everything but mutation. 1/n
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Hannah Moots @mootspoints.bsky.social · 20/07/2025
New preprint comparing aDNA preservation and recovery rates during extraction from all three ossicles and the petrous. Congrats @compevohumang.bsky.social!
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Pontus Skoglund @pontus-skoglund.bsky.social · 14/04/2025
Join us at the Royal Society in London 14 November for a day on Ancient genomes, human biology and medicine! Many slots are reserved for talks from submitted abstracts related to the topic, alongside speakers Svante Pääbo, Priya Moorjani, @mathiesoniain.bsky.social and Lluis Quintana-Murci.
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Tom Booth @boothicus.bsky.social · 18/07/2025
Nifty preprint led by @mathiesoniain.bsky.social comparing femur length as a proxy of stature to genetic variants linked to height today. Many key insights, but main one for me is that variants responsible for lactase persistence are strongly associated with height in ancient but not modern people.
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Hanbin Lee @epigenci.bsky.social · 19/07/2025
My talk from this year's probgen is finally out. Where do linear mixed models and random effects come from? They emerge from *mutations* on Ancestral Recombination Graphs.
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Shai Carmi @shaicarmi.bsky.social · 17/07/2025
Two useful new reviews on ancestry inference in population genetics: onlinelibrary.wiley.com/doi/10.1111/... genomebiology.biomedcentral.com/articles/10....
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Tom Booth @boothicus.bsky.social · 18/07/2025
A difficulty in scrutinising ancient DNA from the outside is that the original methods are discussed in arcane terms in separate papers cast across the innumerable winds of scientific publishing. Here are 2 papers which attempt to discuss collections of common methods with plainer language.
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Bastien Llamas @dnatimetravel.bsky.social · 04/07/2025
It started with a meeting between @mp-williams.bsky.social) and Robbi Davidson during the last @isbarchaeology.bsky.social conference (Tartu, 2023). I remember them sitting at the bar after lunch, engrossed in their discussion—that moment was even captured by the event photographer 🧵1/n
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ISBA11 Turin @isba11.bsky.social · 01/07/2025
Get excited for ISBA11! The conference program is now online! www.isba11.com/programme #ISBA11 #biomoleculararchaeology #Archaeology #Archaeology #archaeologist @isbarchaeology.bsky.social @archaeobiomics.bsky.social
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HAAM-community @haam-community.bsky.social · 11/06/2025
👇 Make sure to register for our webinar happening next week!
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Stephan Schiffels @stschiff.bsky.social · 03/06/2025
Open position at @unileipzig.bsky.social for professor of archaeology of the antique Mediterranean! www.uni-leipzig.de/stellenaussc...
uni-leipzig.de
Professur für Archäologie des antiken Mittelmeerraumes und seiner Umwelt (W2)
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Jonathan Pritchard @jkpritch.bsky.social · 01/06/2025
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
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Tina Saupe @tinasaupe.bsky.social · 13/05/2025
🥳 We're back with a new edition of our HAAM-radio webinar series! Come and be part of the development from a reporting scheme for aDNA samples & seqdata! #aDNA #workshop #humanDNA #sequencing
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ADαPT Laboratory Facility @adapt-lab-ubc.bsky.social · 21/05/2025
Hello Bluesky! We are a specialized laboratory for ancient DNA and protein analysis, led by Prof. Camilla Speller and located at UBC in Vancouver, Canada. Follow us for lab updates, or visit our website (link in profile) #archaeology #palaeoproteomics #ancientDNA #ZooMS #BCarchaeology
sites.google.com
ADαPT Facility
Welcome to ADαPT, a dedicated facility for the analysis of ancient DNA and proteins, located on the University of British Columbia’s Point Grey campus and on the traditional, ancestral, and unceded te...
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Adam "Ben" Rohrlach @brohrlach.bsky.social · 28/04/2025
Long after we first had the idea, BREADR has just been published in the Journal of Open Source Software (@joss-openjournals.bsky.social). A huge thanks to Jono Tuke, Divy Popli and Wolfgang Haak for the support. #ancientDNA #genetickinship doi.org/10.21105/jos...
doi.org
BREADR: An R Package for the Bayesian Estimation of Genetic Relatedness from Low-coverage Genotype Data
Rohrlach et al., (2025). BREADR: An R Package for the Bayesian Estimation of Genetic Relatedness from Low-coverage Genotype Data. Journal of Open Source Software, 10(108), 7916, https://doi.org/10.211...
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Harald Ringbauer @hringbauer.bsky.social · 23/04/2025
Check out our ancient DNA paper on the maritime Punic civilization! 🦴🧬🌊 We find that their Levantine Phoenician cultural ancestors contributed surprisingly little ancestry to Punic sites in the central and western Mediterranean! (1/4) doi.org/10.1038/s415... #aDNA #PopGen #Punic #Phoenician
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