AbstractMotivation. Recent advances in inference of the ancestral recombination graph (ARG), which describes how segments of chromosomes trace back through

Large-scale genome initiatives are transforming biodiversity genomics, but genomes remain taxonomically sparse and difficult to compare across species. Kapli and colleagues argue that natural history ...

Sheeppox virus (SPPV) is a major livestock pathogen causing economic hardship through reduced production and death of vulnerable sheep, with written descriptions of sheeppox-like disease recorded sinc...

The authors present Gnomix, a local ancestry framework that delivers leading accuracy across diverse admixed datasets on both whole-genome and array data with high efficiency, together with Gnofix, it...

Abstract. Proteins and non-coding RNAs are functional products of the genome that are central for crucial cellular processes. With recent technological adv

Letter to the Editor

Newly developed methods enable construction of Icelandic haplotypes and mapping of population-scale short reads to a pangenome by reducing reference bias and improving discovery in low-mappability reg...

The field is generating more new discoveries than ever, but significant setbacks for students and many researchers.

Analysis of one million diverse genomes yields mutations associated with lower risk of diabetes, heart disease and other ‘cardiometabolic’ conditions.

Two leg bones found on the seabed near Taiwan have been identified as Denisovans, and their size suggests these hominins stood up to 190 centimetres tall

Abstract. Research evaluation systems place increasing emphasis on scientific impact, yet their consequences for researchers themselves remain underexplore

Today in Science and science: Ice age hunters’ penchant for female mammoths, a detailed vagal map, and more

Northeast Africa and Southwest Asia present a rich record of hominin occupations between ca. 100 and 50 thousand years ago (ka) at a critical biogeogr…

Ancient genomes challenge views of close kinship in multiple Christian burials, revealing flexible traditions around children.

A research team at the University of Illinois Urbana-Champaign is urging the scientific community to reform how it uses genetic technologies for wildlife conservation

npj Biodiversity - Middle Holocene survival of marsupial megafauna on the north coast of New Guinea

Protein data from the Rising Star cave system show the known sample of this species is entirely female.

Genetic sequencing of multiple late Neanderthals living less than 52,500 years ago provides an overview of genetic diversity and demonstrates that even low-coverage nuclear genome data can increase re...

Analyses of ancient DNA from hunter-gatherers near Lake Baikal in southeast Siberia around 5,500 years ago indicate that highly virulent Yersinia pestis emerged earlier than previously estimated, far&...

ALIGN is an Indigenous-led alliance, supported by dedicated non-Indigenous allies. We provide a range of resources for Community, Researchers and Health Professionals.

The transformation of the Roman world [fourth to ninth centuries common era (CE)], culminating in the Western Roman Empire’s fall, marked a fundamental transition in European history. Key questions pe...

There is a familiar narrative in the way Aboriginal heritage is discussed in Western Australia.It's a decades-old plot concerning 'heritage rorts', 'price gouging'[1], and delay and inefficiency in se...

Near Oceanic populations harbor substantial cultural, phenotypic, and genetic diversity yet are drastically underrepresented in human genomics. We generated 177 high-coverage Near Oceanian whole genom...

Genetic introgression from Neanderthals and Denisovans shaped modern human genomes; however, introgressed structural variants (SVs ≥ 50 base pairs) remain challenging to discover. We integrated high-q...

Paleogenomic analysis of cave lions spanning >100 kya shows that extinct cave lions formed a long-diverged evolutionary lineage from modern lions, with distinct demographic histories and lineage-speci...

The out-of-Africa migration, in which ancient humans went on to inhabit every other continent except Antarctica, may not have been one moment in time, but a long and slow process. Columnist Michael Ma...

YouTube video by Wildlife Messengers

An unexpected trace of the rainforest lays inside a sealed tomb on Peru’s arid central coast: colorful feathers from Amazonian parrots. Did they keep the birds alive? What groups or institutions parti...

Pre-Inca elites wore headdresses made of feathers from Amazonian macaws

Here, the authors combine ancient DNA, stable isotopes, and computational modeling to study colorful feathers from a pre-Incan tomb in Peru. They identify four species of parrots, which were likely ca...

The analysis of ancient DNA (aDNA) has gained considerable momentum over the past decade , allowing the study of extinct or extant genomes from organisms that lived up to 2.5 million years ago. This h...

Research engineer, Department of Organismal Biology, Uppsala University