Authors present a deep learning model that recognises antibiotic modes of action (MoA) directly from brightfield images. Their proposed method complements traditional growth inhibition assays in the s...

Are you interested in investigating basic mechanisms in splicing regulation and gene expression? Our research group was launched in September 2024 and is hosted at the Institute of Molecular Infection...

Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by l…

At the HIRI, we do not just value excellent research. Short distances, an open door policy, and a good working atmosphere—this is what distinguishes us from others. Have a look at our current job…

Nature Microbiology, Published online: 03 February 2026; doi:10.1038/s41564-026-02275-wA near-complete model for the complex structure of the Campylobacter jejuni flagellar motor revealed different mechanisms of assembly, activation and stability from the simple ‘classical’ flagellar model. Some of the additional motor structures in C. jejuni are conserved and only found in species of Campylobacterota, whose ancestor likely co-opted type IV pilus components from bacteria in the deep ocean.

Uropathogenic Escherichia coli infection of a murine prostate organoid model reveals a bacterial FimH–host prostatic acid phosphatase adhesin-receptor interaction enabling invasion and replication wit...

Abstract. Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular surv

A fired public-health official, a mosquito breeder and a baby with a smile seen around the world. These are just a few of the remarkable people chosen for Nature’s 10.

Introduction Antimicrobial resistance (AMR) is one of the most urgent global health threats projected to cause up to 10 million deaths per year by 2050. The AI4AMR project brings together teams from I...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Abstract. The advent of high-density mutagenesis and data-mining studies suggest the existence of further coding potential within bacterial genomes. Small

Transport machineries are crucial for antibiotic resistance, but their regulation by external cues is poorly understood. This study identifies environmental chemicals that regulate transporter transcr...