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The Ca2+ channel Orai1 in microglia links systemic inflammation to depressive-like behaviors in mice.

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Our findings highlight actionable levers to advance equity. Addressing participation gaps and raising awareness of gender disparities are essential to foster inclusive visibility, empower women, and strengthen scientific innovation.

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact s...

The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.

Very nice time spent with our colleagues and friends Rosely Zancopé, Dayvison Freitas, Rodrigo De Almeida Paes & Priscila Marques de Macedo at INI/Fiocruz - Instituto Nacional de Infectologia Evan...

Here, the authors use single-cell spatial transcriptomics to profile the airway wall landscape in health and during asthma. Discrete proinflammatory ecosystems containing alarmins, chemokines and a un...

AbstractBackground and Aims. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract, established as a risk facto

Nature Reviews Microbiology, Published online: 02 May 2025; doi:10.1038/s41579-025-01180-zIn this Review, van de Veerdonk and colleagues explore Aspergillus fumigatus biology, the host immune responses and the fungal mechanisms of immune evasion, as well as emerging challenges such as virus-associated pulmonary aspergillosis and azole resistance, and reflect on future directions for therapeutics and patient care improvement.

Fungi can keep us healthy or cause disease. As climate change drives fungi to adapt, learn how we can harness the benefits and tackle the threats.

Cell Death & Disease - Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis