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Marie-Julie (MJ) Favé

@mjfave.bsky.social
1.1K followers 846 following 37 posts

Associate Prof at Concordia University Computational Genomics Lab & Environmental Human Health PhD. Loves data. Montrealer Lab website: mariejuliefave.weebly.com 🚲

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Marie-Julie (MJ) Favé @mjfave.bsky.social · 6h
Look, I now officially own a tiny wet lab 💙🧬🧫
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Mike Keesey @tmkeesey.bsky.social · 01/10/2026
PhyloPic is having an October fundraiser. The goal is to raise enough money to cover web hosting for the past six months. Please share the link, and chip in a bit if you can! www.phylopic.org
phylopic.org
PhyloPic
PhyloPic is an open database of free silhouette images of animals, plants, and other life forms, available for reuse under Creative Commons licenses. Download silhouettes for use in educational materi...
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Jeffrey Townsend @jeffreytownsend.bsky.social · 27/08/2026
An exciting scientific collaboration 🧪 uncovered a gene–environment "collaboration" in colorectal cancer: an inherited MGMT variant predisposes tumors to alkylating DNA damage, red-meat intake amplifies it—and the damage it causes drives oncogenic KRAS mutations. #EvoDevo doi.org/10.1158/1055...
doi.org
Germline Predisposition to Oncogenic Alkylating Damage in Colorectal Cancer
AbstractBackground:. Red meat consumption is a risk factor for colorectal cancer and has been linked to tumor alkylating DNA damage. rs16906252-T is a cis expression quantitative trait locus variant a...
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Tony Gamble @tonygamble.eurosky.social · 27/08/2026
New collaborative paper from the lab on gecko sex chromosome and genome evolution! 🧪🦎 www.science.org/doi/10.1126/...
science.org
Genomic predisposition is associated with the direction of sex chromosome evolution
Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 ge...
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Josh Weinstock @joshweinstock.bsky.social · 25/08/2026
Excited to share our latest foray into studying the ways in which germline variation gives rise to somatic variation in aging blood: www.medrxiv.org/content/10.6... In work led by @prarthana-s-r.bsky.social , we map how common and rare germline variation links to (somatic) passenger mutations 🧬🧵👇
medrxiv.org
Multi-ancestry analysis of 791K whole genomes reveals the genetic, geographic, and phenotypic correlates of somatic passenger mutations in blood
Clonal hematopoiesis (CH), an aging-related expansion of hematopoietic stem cell (HSC) clones, is associated with hematologic malignancy, cardiovascular disease, and mortality. Most clonal expansions,...
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Eric Topol @erictopol.bsky.social · 17/08/2026
The cancer mortality hazard among pilots and flight attendants. An analysis of 503 occupations, including ground-based aviation workers and nuclear technologists, found that pilot and flight attendants had the highest proportion of radiation-related cancer deaths jamanetwork.com/journals/jam...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 02/07/2026
See you at home next year!!! Please covid and allies, don’t ruin this again. #SMBE26 #SMBE
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 29/06/2026
Want to learn about adapting computational pipeline from human cancer to wildlife and soon captive #penguins WGS high coverage data? Visit poster #115 at 6pm Main Hall today and chat with Isabel! #SMBE2026
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 17/06/2026
That’s a job for Four Season Total Landscaping
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Rajendhran Rajakumar @rajeerajakumar.bsky.social · 30/04/2026
Leave it to the heart to BEAT cancer: How the beating of the heart suppresses tumor proliferation through mechanical load. @science.org www.science.org/doi/10.1126/...
science.org
Mechanical load inhibits cancer growth in mouse and human hearts
The heart rarely develops cancer, and, at the same time, it lacks regenerative capacity, as cardiomyocytes stop proliferating after birth. This suggests that mechanisms limiting cardiac regeneration m...
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Laurie! Live! @laurie-merrell.bsky.social · 05/06/2026
the cancer news seems great but it is very sad for buses that this is the analogy someone would reach for. real monkey's paw outcome for "raise awareness of bus reliability and bus bunching"
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Tschopp Lab @tschopplab.bsky.social · 14/05/2026
One of my dream projects, ever since joining here in Basel, out now in @nature.com : single-cells 🤝 eco-morphological proxies rdcu.be/fiyso How cells and tissues adapt to dietary niches... Thanks and congrats to Antoine, Walter, and all the other co-authors for this great collaboration!! 🙏🥳
rdcu.be
Adaptive cellular evolution in the intestine of hyperdiverse cichlid fishes
Nature - Single-cell transcriptomics combined with morphological and ecological data show that the rapid evolutionary radiation of cichlid fishes in Lake Tanganyika was accompanied by dietary...
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 14/05/2026
Trump’s rollback of toxic gas rules limits EPA’s authority to protect public health, analysis says www.theguardian.com/us-news/2026... On the war against pollution, Donald Trump and Republicans are on the side of pollution, and making your family sick.
theguardian.com
Trump’s rollback of toxic gas rules limits EPA’s authority to protect public health, analysis says
Ethylene oxide (EtO) is about 60 times more carcinogenic than believed in 2006, research finds
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
Collectively, mapping the landscape of autosomal mCAs in populations of diverse ancestry illustrates similarities but also highlights important ancestry, geographic, and sex differences.
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
We also showed how mCAs impact blood transcriptomes, implicating stabilizing selection as a mechanism by which copy number gain mutations are tolerated in healthy blood.
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
We identified autosomal mCA hotspots that were ancestry- and sex-specific, mapped novel ancestry-specific germline variants associated with autosomal mCA prevalence, and estimated heritability rates to quantify the germline genetic contribution to autosomal mCA variance.
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
We profiled mCA, large chromosomal mosaic alterations in the blood of >60,000 participants European-descent and African cohorts, including a founding population cohort in Quebec, and individuals from within South, Central, West and East Africa.
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
New preprint live! www.medrxiv.org/content/10.1... Geography, Ancestry, Age and Sex Shape Somatic Autosomal Mosaic Chromosomal Alterations in Blood
medrxiv.org
Geography, Ancestry, Age and Sex Shape Somatic Autosomal Mosaic Chromosomal Alterations in Blood
Clonal hematopoiesis, through the age-associated accumulation of somatic mutations in blood, is strongly associated with hematological malignancies and other chronic diseases. These mutations have lar...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 20/10/2025
My first time awarding a PhD to a candidate, what a precious honour. Keep up the good work, students!
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Michael Hoffman @michaelhoffman.bsky.social · 17/10/2025
Now: @jsdron.bsky.social (JD): Age- and BMI-dependent genetic architecture of blood lipids in 2.5 million individuals from globally diverse populations #ASHG25 🧪🧬🖥️
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Graham Coop @gcbias.bsky.social · 15/10/2025
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 15/10/2025
Come join us in beautiful vibrant Montréal! Job opening for a CRC position in Applied Synthetic Biology at Concordia University. www.concordia.ca/jobs/artsci/... #ASHG25 #ASHG2025
concordia.ca
Canada Research Chair Tier II in Applied Synthetic Biology | Faculty of Arts and Science - Concordia University
The Department of Biology in the Faculty of Arts and Science at Concordia University invites applications for a tenure track faculty position and Tier II Canada Research Chair (CRC) in Applied Synthet...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 14/10/2025
I will be missing #ASHG25 but please keep posting about it! I can't wait to read all the updates of great science and people! #FOMO
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Denis Jabaudon @djabaudon.bsky.social · 19/09/2025
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...
science.org
Cell-extrinsic controls over neocortical neuron fate and diversity
Cell-extrinsic cues are key for neocortical cell identity and diversity.
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Mary Williams @PlantTeaching @plantteaching.bsky.social · 15/08/2025
Interesting, well-written article from the Guardian. www.theguardian.com/world/2025/a...
theguardian.com
Arctic glaciers face ‘terminal’ decline as microbes accelerate ice melt
Scientists in Svalbard in race to study polar microbes as global heating threatens fragile glacial ecosystems
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 15/08/2025
Music to my ears. This is brilliant. Either 90% of us can claim to be better musicians than Beethoven or… maybe just maybe polygenic scores aren’t perfect?
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Nature @nature.com · 23/05/2025
Nature research paper: Multigenerational cell tracking of DNA replication and heritable DNA damage go.nature.com/4jxWDMJ
go.nature.com
Multigenerational cell tracking of DNA replication and heritable DNA damage - Nature
A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may resemble early events during cancer development.
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Onisillos @onisillos.bsky.social · 23/05/2025
I never thought about wool as a possible route of infection. www.nature.com/articles/d41...
nature.com
This ancient pathogen became deadlier when humans started wearing wool
Ancient genomes reveal that a bacterial fever jumped from human-borne ticks to lice around the time wool textiles became common.
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Chris McCray @mccraywx.bsky.social · 06/05/2025
On parle souvent de l'importance de la fluidité automobile au centre-ville. Pourtant, seuls 21% des déplacements vers le centre-ville se font en voiture. On devrait plutôt parler de comment améliorer le transport collectif (55%) et actif (23%) si on veut attirer les clients et travailleurs au c-v.
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Jesse Shapiro @bjesseshapiro.bsky.social · 24/04/2025
Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely. mcgill.wd3.myworkdayjobs.com/en-US/McGill...
mcgill.wd3.myworkdayjobs.com
Assistant Professor (Research), Department of Microbiology & Immunology, (C2-240724)
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 24/04/2025
I’ll take it as a compliment today ☺️ maybe this retinol cream is working 😅
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 23/04/2025
Getting mistaken for a student at my final exam ✅ Should I have pretended and write my own exam? 😁
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 13/03/2025
This morning, teaching an undergraduate class in population genetics gave me hope and confidence for the future, those students are rocking it!!
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 13/02/2025
Thanks your post made me realize how much I needed to hear that today ☺️
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senjutisaha.bsky.social @senjutisaha.bsky.social · 12/02/2025
To the women in science. To the allies in science. To the ones who lift each other up. I spend my life in science, constantly trying to figure out where I fit in. At times, it feels like pushing against an invisible force-one that questions, doubts, resists. But through it all, I am never alone. 🧵
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 11/02/2025
Sex determination in cephalopods: hemizygosity (ZO) in females and ZZ males, and predates the radiation of the group 480 milions years ago. Fascinating work by Andrew Kern lab!
cell.com
Cephalopod sex determination and its ancient evolutionary origin
Coffing et al. assemble a chromosome-level octopus genome assembly, revealing that the female octopus has just one sex chromosome (ZO karyotype), and males have two (ZZ karyotype). They conduct genomi...
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Eric Topol @erictopol.bsky.social · 11/12/2024
Our blood tests are interpreted by average reference values. That's missing a lot of rich information! Each person has their own tightly regulated setpoints. One healthy person's complete blood count setpoint can be differentiated from 98% of other healthy adults. www.nature.com/articles/s41...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 06/12/2024
When even your office phone knows you only as per your initials. #LongNameProblems
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 04/12/2024
Hybridization lead to a reduced rate of LOH and influence adaptation - Very cool work by the Landry lab!
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Bluesky @bsky.app · 03/12/2024
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
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Leopold Parts @leopoldparts.bsky.social · 02/12/2024
Does my mutation have the same impact as yours? Population genetics 🤠 🥸 🤓 🤡 meets single cell CRISPRi ⚡ ! www.biorxiv.org/content/10.1... Led by Claudia Feng, Oliver Stegle, Britta Velten, @sangerinstitute.bsky.social .
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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R stats memes @rstats-sky.bsky.social · 27/10/2024
#RStats that DeLorean though!
Different statistical software/programming languages represented as different types of cars:

Excel: Shown as a broken-down car with a person holding their head in frustration
SPSS: Represented by a vintage brown station wagon from the 1980s
SAS: Depicted as a classic black 1930s luxury car
Python: Shown as a sleek, modern blue sports car with glowing effects
MPLUS: Represented by a DeLorean with its distinctive gull-wing doors
STATA: Shown as a modern blue SUV
MINITAB: Depicted as a vintage red Vauxhall Chevette or similar compact car
R: Represented by a scene from Mad Max: Fury Road with multiple modified post-apocalyptic vehicles
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 24/11/2024
Would love to be included 😊
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 24/11/2024
LoF and duplications correlated effects on phenotypes lead to an interesting paradox:
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Dr. Amy Lee @minisciencegirl.bsky.social · 21/11/2024
Every year, >200K newborns die from sepsis. Our team used machine learning to develop a set of genes that can predict neonatal sepsis risk using at birth blood samples. www.thelancet.com/journals/ebi...
thelancet.com
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
Despite appearing healthy at birth, neonates who later developed EOS already had distinct whole blood gene expression changes at birth, which enabled the development of a 4-gene predictive signature f...
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 21/11/2024
Oh the answer key would be great indeed!
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 21/11/2024
Awe thanks! Hope to cross paths soon again!
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 21/11/2024
SMBE in Quebec city in 2027! woot woot! 🧬🖥️
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Marie-Julie (MJ) Favé @mjfave.bsky.social · 21/11/2024
Thanks so much! using this to build my new undergrad pop gen course next winter 🤗
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🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 10/11/2024
Genomics, evolution, and more starter pack! Help build community with this starter pack. This list is currently incomplete. Want to be included? Reply and I will remedy that! go.bsky.app/JjvzkWU
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