German chancellor says reset vital to help Europe become more unified to face huge security and economic challenges

Shares slump on both sides of the Atlantic, and across Asia-Pacific, as US dollar falls to six month low after US President Trump’s ‘liberation day’

Excalibur Healthcare, which supplied the UK Government with tens of millions of pounds worth of unusable PPE, ultimately folded owing taxpayers £22 million

And it is not a very convincing vindication of Brexit.

Ursula von der Leyen says tariffs a ‘major blow’ to world economy, as US dollar falls to six month low after US President Trump’s ‘liberation day’

Watching the New Jersey senator hold court for 25 hours felt radical and cathartic, says Guardian columnist Emma Brockes

Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated

Thanks to Trump’s administration, the US could soon have to fight wars to get things that, just a few weeks ago, were there for the asking, says professor Timothy Snyder of Yale University

Number of women having a baby in Camden, north London, has declined by almost 30%

Ukraine’s president said drone attacks just hours after ceasefire talks were ‘a clear signal to the whole world’

Presence of long-chain alkanes in rock raises new questions about possible existence of life billions of years ago

For 19 years he has held the powerful to account on a show that attracts huge audiences around the world. Now it is over. He discusses his anger with management, his pride in his team – and what he’ll...

Call is at odds with UK Labour’s own post-Brexit red lines.

Protesters accuse PM of continuing Gaza war for political reasons and ignoring plight of hostages still held by Hamas

Historic levels of spending on military and infrastructure secured in Bundestag with last-minute backing of Greens

Five years after the first lockdown, millions of lives are still being ruined by this debilitating disease. You wouldn’t know it, says Guardian columnist Frances Ryan

Jack Aaron, whose past comments on controversial leaders led to widespread criticism, is now overseeing candidate selection