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Matt Loose

@minomatt.bsky.social
2.6K followers 582 following 113 posts

Sequencing, adapting and exploring genomes. linktr.ee/matt.loose

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Matt Loose @minomatt.bsky.social · 17/07/2026
It’s possible, but it doesn’t end up looking particularly useful given the other constraints of the interface?
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Matt Loose @minomatt.bsky.social · 16/07/2026
Missing having the ability to look at nanopore runs from your iOS device? I do and so we’ve had a play building on @nanoporetech.com minknow api. If you want to test CodPilot you can here. testflight.apple.com/join/DgMNMY1A
CodPilot Screenshot
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Matt Loose @minomatt.bsky.social · 13/07/2026
UK Genome Science - early bird deadline is getting close… and you know what they say about the early bird. Not sure what that really has to do with it, but if you want to come along please do register.
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Matt Loose @minomatt.bsky.social · 02/07/2026
A great lesson in life is to be more like Mike Hubank (one of the nicest out of many nice people in Genomics!) - but on this specific occasion we should all be more like Mike and book our tickets for UK Genome Science - see www.genomescience.org.uk for more details.
genomescience.org.uk
Genome Science UK 2026
Manchester University
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Matt Loose @minomatt.bsky.social · 02/07/2026
Hey everyone - I don’t post often now - but don’t forget about the fabulous UK Genome Science meeting being held in Manchester this year from the 14th-16th September. Early bird registration closes at the end of July. Info here - www.genomescience.org.uk
genomescience.org.uk
Genome Science UK 2026
Manchester University
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Reposted by Matt Loose
Josh Quick @scalene.bsky.social · 22/05/2026
New preprint from us! 🦠 Clinical metagenomics is great for sequencing pathogens directly from patient samples but for some protocols sensitivity for RNA viruses lags behind bacteria & fungi. We have shown why, and how to fix it. www.medrxiv.org/content/10.6...
medrxiv.org
Library preparation strategy critically impacts RNA virus sensitivity in clinical metagenomics
Clinical metagenomics uses sequencing for culture-independent identification of pathogens directly from clinical specimens. While a number of protocols claim to be pathogen agnostic, sensitivity for R...
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Matt Loose @minomatt.bsky.social · 20/05/2026
I’ve not seen released example data. But it’s already shipping in MinKNOW so it should be possible to generate some.
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Matt Loose @minomatt.bsky.social · 20/05/2026
Very cool to see noise cancelling headphones for adaptive sampling #nanoporeconf
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Matt Loose @minomatt.bsky.social · 30/04/2026
Yes. None of them correspond to me. They are no longer being sent as far as I can see.
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Matt Loose @minomatt.bsky.social · 30/04/2026
Yeah - I’ve had 3/4 per minute for the last hour. And they are not mine… @cshlpress.bsky.social there’s an issue.
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Matt Loose @minomatt.bsky.social · 30/04/2026
@cshlpress.bsky.social something wrong with the CSHL alerts emails? It seems to be sending random email notifications to people?
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Matt Loose @minomatt.bsky.social · 10/11/2025
Very interesting day at the genomics England long read summit. And great to catch up with @generoom.bsky.social and more!
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Matt Loose @minomatt.bsky.social · 10/11/2025
Lots of nice information in this presentation.
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Matt Loose @minomatt.bsky.social · 10/11/2025
Very nice summary of a number of cohorts and chemistries across @nanoporetech.com from genomics England.
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Matt Loose @minomatt.bsky.social · 07/10/2025
Spent the last hour helping solve quadratic equations for my son’s maths homework. I knew my A-level maths would one day come in useful. And it has. To do his A-level maths.
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Matt Loose @minomatt.bsky.social · 25/09/2025
PhD opportunity available on epigenomics/trasncriptomics as part of the network of clinicians and researchers working in glioblastoma research at @uniofnottingham.bsky.social Using a wide range of tech and methods but definitely long reads @nanoporetech.com - more at lnkd.in/eBtrtZiM
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Matt Loose @minomatt.bsky.social · 22/09/2025
“the service that is provided” - discuss…
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Nick Loman @pathogenomenick.bsky.social · 22/09/2025
A bit like spiralling publication costs we need to start having a proper discussion around lab equipment servicing costs. These are often completely disproportionate to the cost of instrument and the service that is provided and seem to serve as a cash cow for vendors.
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Matt Loose @minomatt.bsky.social · 19/08/2025
Great to see this paper out www.nature.com/articles/s41... including Chris Moore of the Nottingham DeepSeq team. Chris took @nanoporetech.com Mk1Cs out to Columbia and sequenced chocolate. Coverage www.theguardian.com/science/2025... and institutions.newscientist.com/article/2492....
theguardian.com
Scientists claim to have unlocked ‘secret sauce’ needed for fine chocolate
Results of studying cocoa bean fermentation in Colombia could pave way to manipulate flavour, say researchers
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Matt Loose @minomatt.bsky.social · 17/07/2025
For @nanoporetech.com geeks I’ve just been pointed at this very helpful site - nanoporetech.github.io/ont-output-s... - I hadn't seen this before and it's very useful!
nanoporetech.github.io
Oxford Nanopore Output Specifications
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Matt Loose @minomatt.bsky.social · 21/05/2025
Thanks for all your support Mike!
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Matt Loose @minomatt.bsky.social · 21/05/2025
Really pleased that this paper is out - academic.oup.com/neuro-oncolo... thanks to all our collaborators far and wide who have helped and of course @nanoporetech.com
academic.oup.com
ROBIN: A unified nanopore-based assay integrating intraoperative methylome classification and next-day comprehensive profiling for ultra-rapid tumor diagnosis
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Matt Loose @minomatt.bsky.social · 09/05/2025
UK Genome Science meeting - Newcastle. 9th - 11th July 2025. Great speakers. Great community. Early bird registration-16th May Abstract submission-23rd May Registration close-26th June If you want that sweet sweet early bird deal - get going quick! www.genomescience.org.uk
genomescience.org.uk
Genome Science UK 2025
Newcastle University
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Matt Loose @minomatt.bsky.social · 08/05/2025
RIP MK1B. You always punched way beyond your weight. @nanoporetech.com about that mk1D…
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pore-xy.bsky.social @pore-xy.bsky.social · 11/04/2025
Faster Brain Tumour classification now being validated in Sydney @lavsat.bsky.social based on the work of @minomatt.bsky.social and collaborators youtu.be/sfykXrvSs28
youtu.be
New device that can detect tumours within 24 hours | 9 News Australia
YouTube video by 9 News Australia
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Matt Loose @minomatt.bsky.social · 28/03/2025
UK Genome Science 2025 is going live for this year - www.genomescience.org.uk - get registering!
genomescience.org.uk
Genome Science
9th - 11th July 2025, Newcastle University
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Matt Loose @minomatt.bsky.social · 22/03/2025
A benefit of being on the other side of the world is being able to watch the sprint race live.
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Matt Loose @minomatt.bsky.social · 19/03/2025
Real pleasure to be presenting at the @nanoporetech.com #WYMM event in Melbourne Australia today. Great to see the pores work equally well upside down. And at last - socks! Though I still think they should be the long sock… youtu.be/zxI-pcLj9XE?...
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Matt Loose @minomatt.bsky.social · 18/03/2025
Whilst I can’t disagree, I feel this also wouldn’t be specific enough. There have been many many things sad people have obsessed over for 15 years.
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Matt Loose @minomatt.bsky.social · 18/03/2025
I know university challenge is famed for its attention to detail but that would be too niche even for paxman. And I’m now setting my poRe timer…
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Matt Loose @minomatt.bsky.social · 18/03/2025
Just wish I knew what the actual question was… “FASTA, FASTQ and FAST5…” - fill in the blanks?
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Matt Loose @minomatt.bsky.social · 05/03/2025
Great to be visiting @nanoporetech.com as part of a cns Nanopore symposium meeting with pathologists and clinical scientists to discuss the application of nanopore sequencing in the clinic.
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Matt Loose @minomatt.bsky.social · 28/02/2025
That was Marco island the other night yes.
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Matt Loose @minomatt.bsky.social · 28/02/2025
No filter.
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Matt Parker @bioinfomatt.bsky.social · 27/02/2025
#AGBT2025 #AGBTGM has been incredible. Lucky to be part of the event with @nanoporetech.com - as always we were so looked after by our amazing events team! (Photo credit to @minomatt.bsky.social)
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Matt Loose @minomatt.bsky.social · 23/02/2025
I can’t stop watching it slowly spin.
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Jonathan Coxhead @4130chromo.bsky.social · 30/01/2025
Well done @fogenomics.bsky.social another fantastic meeting ✨ Caught up with so many friends 🙏 Great speakers and even better networking 🧬🧬 #FOG2025 See you all in July at Genome Science, in Newcastle 🥳
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Matt Loose @minomatt.bsky.social · 28/01/2025
To be fair I can see why you might of been confused
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Matt Loose @minomatt.bsky.social · 28/01/2025
Oracle.
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Matt Loose @minomatt.bsky.social · 28/01/2025
They’ve even got a whale…
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Matt Loose @minomatt.bsky.social · 28/01/2025
For info - it’s DeepSeq for all your next generation sequencing needs. Deep Seek will do something completely different…
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Matt Loose @minomatt.bsky.social · 28/01/2025
They said I’d be able to check my accounts more quickly… everything would be simpler. 15 minutes later - I still can’t see how much money is in my account. Could someone at a university tell me that this system gets better over time? Because so far… it’s exactly as bad as people said it would be.
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Matt Loose @minomatt.bsky.social · 01/01/2025
Not sure - is it an ‘A’?
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Matt Loose @minomatt.bsky.social · 01/01/2025
Fun to see some killer whale poo seq on #bbc2 today using @nanoporetech.com Still want to get a whale read from a whale one day!
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Matt Loose @minomatt.bsky.social · 01/01/2025
Happy New Year all!
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Matt Loose @minomatt.bsky.social · 24/12/2024
Well - this is awkward. According to santatracker.google.com Santa is on his way. But according to Norad www.noradsanta.org/en/map he’s going to take off shortly. Something up with norad?
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Matt Loose @minomatt.bsky.social · 18/12/2024
And so we reach the glorious time of year where authors try to push papers to editors to “get them off the desk” whilst editors try to clear their desks for the break. Referees try to rapidly return reports to editors and nothing will happen to anything for a good 10 days…
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Matt Loose @minomatt.bsky.social · 12/12/2024
Nottingham Nanopore contingent out to celebrate Dr Munro
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Matt Loose @minomatt.bsky.social · 05/12/2024
I think that’s generous of you. I’m afraid unless they are of immediate relevance I just hit delete. Especially the ones that provide vague descriptions and then request a meeting!
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Matt Loose @minomatt.bsky.social · 04/12/2024
If we hadn’t just moved to an oracle based university administration system I am sure Rachael would have been able to supply you with the precise catalog number if you so wished… Sadly that may not be possible now.
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