iiinova — where your digital self keeps evolving

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Genes & Development @genesdev.bsky.social · 18/09/2026

We are saddened by the loss of G&D's long-time Editor, Terri Grodzicker. When Terri stepped down as Editor in 2022, friends and colleagues wrote about her contributions to the research community. We are re-visiting these pieces, and thinking of her. ➡️ genesdev.cshlp.org/content/37/1-2.t…

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Genes & Development @genesdev.bsky.social · 11/09/2026

Read the G&D Perspective: ➡️ genesdev.cshlp.org/content/40/1...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 02/09/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on estrogen receptor binding in endometrial cancer, evolution of cave-derived traits, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 06/08/2026

How do sleep, stress, fear, and hippocampal circuitry shape memory? Explore featured research from Learning & Memory on the neural and behavioral processes through which memories are formed, refined, and sometimes disrupted. Access now: bit.ly/LMFeaturedResearch

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 23/07/2026

Learning & Memory invites submissions for a Special Collection on how epigenetic mechanisms shape memory—and how they change with aging and disease or may be targeted to restore memory function. Guest edited by Dr. Farah Lubin of the University of Alabama at Birmingham. bit.ly/epigenticscollection

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David Crotty @dacrotty.bsky.social · 16/07/2026

Obviously those students should be reading the new book from CSHL Press on how to navigate careers in STEM: www.cshlpress.com/default.tpl?...

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Genome Research @genomeresearch.bsky.social · 07/07/2026

Call for Papers! @genomeresearch.bsky.social is now encouraging submissions for a Special Issue: "Spatial Omics: Technologies, Computation, and Biological Discovery", Guest Edited by Drs. Christina Leslie, Jian Ma, and Jeffrey Moffitt. Submission deadline: Nov. 1, 2026. tinyurl.com/Call-for-pap...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 12/06/2026

How do cells control protein production? This review from the #RNASpecialIssue explores how Ribo-seq and live single-molecule imaging are bringing together genome-wide and real-time views of mRNA translation. Access now: bit.ly/4mjjI8B

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 12/06/2026

Nancy Wexler has spent a lifetime advancing our understanding of Huntington’s disease. In this moving NY Times profile, she reflects on the personal and scientific journey behind her new memoir, "My Life, My Science", published by CSHL Press. Read the article (free access): bit.ly/wexlernytimes

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 05/06/2026

How do researchers make sense of data from millions of individual cells? This review from the #RNASpecialIssue explores how AI and machine learning methods help uncover patterns in single-cell RNA sequencing data, revealing insights into cell identity, function, and disease: bit.ly/4eboUJF

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Genes & Development @genesdev.bsky.social · 05/06/2026

🌟G&D SPOTLIGHT 🌟 G&D is pleased to present a collection of recent articles on RNA biogenesis and regulation. Learn more about small RNA biogenesis, target-mediated miRNA degradation, RNA splicing, ribonucleoprotein granules, and more. ➡️ genesdev.cshlp.org/site/misc/collec…

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 03/06/2026

How can poly(A) site usage be controlled? This review from the #RNASpecialIssue examines strategies to modulate cleavage and polyadenylation sites, highlighting applications in studying alternative polyadenylation and developing new therapeutic approaches. Read more: bit.ly/4sthgOt #RNA #RNABiology

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Genome Research @genomeresearch.bsky.social · 02/06/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on allele-specific splicing in Alzheimer's disease, tissue-specific gene regulation by vitamin B, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 29/05/2026

Can we map miRNAs and their targets in brain tissue? Current spatial transcriptomics methods can't simultaneously measure miRNAs and their target 3′UTRs. This review from the #RNASpecialIssue explores the challenge and emerging solutions: bit.ly/4sv5Dq1 #RNABiology #MicroRNA

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 21/05/2026

RNA function is defined by its interactions. This review from the #RNASpecialIssue surveys new methods to map protein–RNA and RNA–RNA contacts, helping reconstruct RNA interaction networks at transcriptome scale. bit.ly/41KDfWl #RNAbiology #Interactome #Genomics

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 19/05/2026

How well can machine learning predict RNA secondary structure? This review in the #RNASpecialIssue examines current approaches—from deep learning to hybrid models—while exploring the field’s “generalization crisis” and the rise of RNA foundation models. bit.ly/4spSj6s

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 12/05/2026

How well do deep learning models generalize in RNA secondary structure prediction? This Perspective from the #RNASpecialIssue explores the “generalization gap” limiting current methods and how AI is reshaping RNA structure prediction. bit.ly/4dx1lec #RNABiology #RNAstructure #Bioinformatics

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 07/05/2026

Nanopore direct RNA sequencing is reshaping epitranscriptomics — enabling direct detection of RNA modifications and RNA damage across entire transcriptomes with long-read sequencing. New review from the #RNASpecialIssue: bit.ly/3POaGo9 #RNA #Epitranscriptomics #Nanopore

Helicase Motor (Sensor) and Nanopore Sensor

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 04/05/2026

What’s next for RNA biology at system scale? In this Special Issue editorial, the editors frame a shift toward quantitative, integrative approaches, highlighting advances in measuring, modeling, and ultimately manipulating RNA across biological systems. bit.ly/41hv9UJ #RNASpecialIssue

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 30/04/2026

We're pleased to feature a recent Special Issue of RNA showcasing advances in system-level RNA biology—from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond. A strong snapshot of where the field is heading. bit.ly/RNAspecialis...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 10/04/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on somatic mutant alleles in bulk tumor samples, honey bee gut microbiota, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 04/03/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory @cshlnews.bsky.social · 27/02/2026

Vulnerable to Huntington’s Disease, Nancy Wexler devoted her life to research that revealed the HD mutation and produced a test for susceptibility. Read her powerful autobiography published by CSHL Press: "My Life, My Science: Pursuing a Cure for Huntington’s Disease". Pre-order at: amz.cx/3c1w

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Alejandro Montenegro @aemonten.bsky.social · 02/03/2026

A new issue of CSH Protocols is out! @cshlpress.bsky.social The cover image highlights the work by Moss et al., who describe how to use fluorescence flow cytometry and specific AuxInYeast strains to study #maize auxin perception. ⬇️Links below

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 06/02/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on transposable elements in pancreatic cancer, genomic evolution in living fossils, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 06/01/2026

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research the 3D genome organization in breast cancer, assisted reproductive technology mutation rate, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 04/11/2025

The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 21/10/2025

Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not. Now in print + eBook formats: bit.ly/epigeneticsb...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 17/10/2025

Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21. #Epigenetics #MolecularBiology #CellBiology #Genomics

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 02/10/2025

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 03/09/2025

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 04/08/2025

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 01/08/2025

New issue of Genes & Development! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: genesdev.cshlp.org/content/39/15-16.toc

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 02/07/2025

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 03/06/2025

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 07/05/2025

Call for Papers! @genomeresearch.bsky.social is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung (Alice) Lee, and Raheleh Rahbari. tinyurl.com/Call-for-pap... #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 05/05/2025

The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-3...

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Genes & Development @genesdev.bsky.social · 02/05/2025

📽️ G&D Tapes 📽️ G&D author, Jelani Lyda talks about a new study in #GenesDev by Riley et al. reporting the role of ClpCP protease and novel protein MdfA in driving metabolic differentiation and dormancy during bacterial sporulation. #OpenAccess Learn more here: ➡️ tinyurl.com/gd352535

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 17/04/2025

SF3B1: from core splicing factor to oncogenic driver — this #RNASpecialIssue article explores how SF3B1-mutant splicing drives cancer, with insights into prognosis, phenotypes & the need for targeted therapies. bit.ly/4bqmRy2

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Genome Research @genomeresearch.bsky.social · 14/04/2025

SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches. tinyurl.com/Genome-Res-3...

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 15/04/2025

Connecting genotype and phenotype in minor spliceosome diseases. This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 11/04/2025

This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer: bit.ly/3F4Sv8g

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 09/04/2025

Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 07/04/2025

Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay. This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 04/04/2025

This review from the #RNASpecialIssue discusses the distribution, regulation, and mechanisms of cytoplasmic polyadenylation element-binding proteins (CPEBs), highlighting their dual roles in either promoting or repressing gene expression depending on cellular context. bit.ly/41pFqhp

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Cytoplasmic regulation of the poly(A) tail length as a potential therapeutic target

A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

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Cold Spring Harbor Laboratory @cshlnews.bsky.social · 02/04/2025

🧬 This National Children's Book Day, meet the tiny heroes inside us all! Stem Cells to the Rescue from CSHL Press is a science adventure that shows kids how our bodies heal. #ChildrensBookDay #STEMforKids #CSHLPress www.cshlpress.com/default.tpl?...

cshlpress.com

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 02/04/2025

Alternative splicing (AS) is vital for heart function, and its disruption is linked to disease. This #RNASpecialIssue article highlights nonsplicing roles of AS factors and proposes a novel disease mechanism involving pathogenic RNA granules and disrupted AS factor localization. bit.ly/3DkHM9d

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 31/03/2025

Cytoplasmic viruses alter nuclear trafficking, causing RNA-binding proteins (RBPs) to relocate and act as antiviral defenses. This article from the #RNASpecialIssue explores host–virus interactions and the unanswered questions about their mechanisms. bit.ly/3QJOjNG

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Cold Spring Harbor Laboratory Press @cshlpress.bsky.social · 26/03/2025

This article examines how RNA sensors bind ligands and trigger type I interferon-stimulated genes. It also explores how mutations in RNA sensors and RNA homeostasis genes are linked to autoimmune and autoinflammatory diseases. bit.ly/4bowQEb #RNASpecialIssue

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