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Michele Acconcia

@mich-acconcia.bsky.social
141 followers 174 following 13 posts

PhD student in the @gozziale.bsky.social Functional Neuroimaging Lab

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Reposted by Michele Acconcia
Hank Greely @hankgreely.bsky.social · 17/08/2026
Dear @economist.com, More disclosure of risks (unknown but possibly substantial) & effectiveness (at best very low even in the 1 2019 article you cite & perhaps not to improve much) won't help the embryos involved make better decisions about their futures. Caution needed. I regret your position.
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Ben Hayden @benhayden.bsky.social · 16/07/2026
Hard to overstate the importance of this paper. Acategoricality and mixed selectivity together kill a lot of sacred cows. For starters, place cells aren't real, in that they are not a meaningful category. They are just a thing we scrape out of the data. Scientists focus on them because...
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Bertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 03/06/2026
The representational geometry of emotional states in basolateral amygdala www.nature.com/articles/s41...
nature.com
The representational geometry of emotional states in basolateral amygdala - Nature Neuroscience
O’Neill, Posani and colleagues show that while single amygdala neurons encode multiple emotional state-related variables (for example, valence, fear and safety), population-level geometry can enable o...
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Reposted by Michele Acconcia
Bohan Zhao @bohanzhao.bsky.social · 27/05/2026
So I built a small tool that merges Allen CCFv3 with the traditional bregma-relative coordinate system (calibrated with Paxinos & Franklin's Atlas). Click any coronal or sagittal section, and get coordinates instantly. bohanzhao.com/Atlas Hope it saves someone a headache 🐭
bohanzhao.com
Mouse Brain Stereotaxic Coordinate Viewer
Free interactive tool: enter bregma-relative AP/ML/DV coordinates to navigate Allen Mouse Brain Atlas coronal and sagittal sections. Brain regions identified in real time.
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Daniel Lakens @lakens.bsky.social · 27/05/2026
Excellent news! Nature is expanding Registered Reports to all the fields in which they publish! A great result by all those proposing this strong solution to publication bias and selective reporting (and getting expert feedback before data collection)! www.nature.com/articles/d41...
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hakwan lau @hakwan.bsky.social · 26/05/2026
authors.elsevier.com/c/1nA3C_KOmx... new paper in Neuron in which we argue that many claims on consciousness in AI & animals etc are inconsistent. they are driven by theories/views that are not really supported by empirical evidence. they confuse subjective experience w/ cognition or perception
authors.elsevier.com
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Alessandro Gozzi @gozziale.bsky.social · 18/05/2026
Our preprint has grown up, and it is now out in @natneuro.nature.com Bottom line: variable patterns of brain connectivity in #autism can reflect distinct underlying biological mechanisms 🧠🐭 Paper: www.nature.com/articles/s41... Mouse fMRI datasets: tinyurl.com/44dwe6dz Detailed explainer below👇
nature.com
Autism subtypes identified using cross-species functional connectivity analyses - Nature Neuroscience
Pagani et al. used cross-species fMRI to reveal two autism subtypes, characterized by lower and higher brain connectivity and linked to synaptic and immune-related pathways, respectively.
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Jess Cardin @jess-cardin.bsky.social · 13/05/2026
Seems unlikely, given how crafty the brain is about getting the most flexibility possible out of a pretty static setup of neurons. Tl;dr for our other work: acetylcholine (ACh) release is wildly non-uniform in space and time! This time, we looked at norepinephrine (NE) release across the cortex.
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Kevin Mitchell @wiringthebrain.bsky.social · 09/05/2026
Hey psychologists, when you're explaining some psychological phenomenon that's perfectly well captured in psychological terms, maybe you don't need to refer to some shitty neuroimaging study with ten people to make it seem more "sciencey"...
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PessoaBrain @pessoabrain.bsky.social · 07/05/2026
𝗠𝗮𝗷𝗼𝗿 𝗱𝗲𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘁𝗵𝗲 𝗹𝗲𝗻𝘀 𝗼𝗳 circuit 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Finally research is considering the functional/ anatomical complexity of the brain. It's not about regions, but how circuits function dynamically. www.cell.com/neuron/abstr... #neuroskyence
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Chiara Pepe @chiarapepe.bsky.social · 29/04/2026
24/04/2026, PhD in Cognitive and Brain Sciences, cum laude 🎓 @cimecunitrento.bsky.social @iitalk.bsky.social What a wonderful journey life is. I am so grateful that I’m still out of words..I’ll let these pictures speak. And yes, my lab really did build me a cardboard Iconeus machine!!
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Evan Gordon @gordonneuro.bsky.social · 22/04/2026
I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...
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Rebecca Saxe @rebeccasaxe.bsky.social · 14/04/2026
Today I taught science communication, and miscommunication, to graduate students at MIT. In the process I stumbled on this great blog post from 2019 about the misinformation related to my Mother and Child Image. Thanks! whoever wrote this. www.feeduk.org/blog/mri-ima...
feeduk.org
Sunday scrolling: the MRI image that misled many mums — feed
It all begins with an idea.
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Alessandro Gozzi @gozziale.bsky.social · 18/03/2026
📢 New preprint from the lab🧠 ▶️doi.org/10.64898/2026.03.12.710517 What does fMRI connectivity actually reflect at the neural level? The natural intuition is: more neural activity = more connectivity! Using cortical perturbations we show this is not necessarily the case: sometimes less is more! 👇🧵
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Kevin Mitchell @wiringthebrain.bsky.social · 21/02/2026
I'm SO tired of people looking for "the neuroscience of X" (meaning uninformative neuroimaging pictures) when *the psychology of X* is right there, doing a perfectly good job...
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Chiara Pepe @chiarapepe.bsky.social · 11/02/2026
🐭🧠 Can fUSI truly map canonical mouse resting-state networks — and how does it compare to fMRI? I’m excited to share the work of my PhD in our new preprint!👉 doi.org/10.64898/202... Go check it out — it’s time to expand your neuroimaging toolkit 🧠🚀
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Serge Ahmed @sergeahmed.bsky.social · 09/02/2026
Can you easily distinguish between value, valence, and salience? Probably not, but the prefrontal cortex of mice seems to achieve this by creating a sort of multidimensional orthogonal neural space, where each dimension corresponds to one of these subjective elements www.nature.com/articles/s41...
nature.com
Prefrontal neural geometry of learned cues guides motivated behaviours - Nature
The dorsomedial prefrontal cortex encodes the value, salience and valence of learned stimuli along distinct neural dimensions, and the geometry of these representations shapes motivated behaviours in ...
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Ben Hayden @benhayden.bsky.social · 23/12/2025
New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵 rdcu.be/eVZ1A
rdcu.be
Rethinking the centrality of brain areas in understanding functional organization
Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...
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Alessandro Gozzi @gozziale.bsky.social · 19/12/2025
Wrapping up 2025 with the lab. Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year. Wishing everyone a peaceful holiday break!
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Nature Reviews Neuroscience @natrevneuro.nature.com · 04/12/2025
How distributed is the brain-wide network that is recruited for cognition? A Perspective by Matthew C. Rosen & David J. Freedman #neuroscience #neuroskyence www.nature.com/articles/s41...
nature.com
How distributed is the brain-wide network that is recruited for cognition? - Nature Reviews Neuroscience
Both localized and distributed views on the functional organization of the brain have been put forward. In this Perspective, Rosen and Freedman examine the degree to which these two views account for ...
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Romain Brette @romainbrette.bsky.social · 18/12/2024
I wrote a book: "The brain, in theory". First chapter and TOC: romainbrette.fr/WordPress3/w...
romainbrette.fr
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Reposted by Michele Acconcia
🐭 Danielle Williams 🐹 @okaydaniellle.bsky.social · 09/11/2025
very nice talk by Joe McCaffrey on functional localization— it’s an easy listen with tons of great information about the debate. m.youtube.com/watch?v=eRmD...
m.youtube.com
Lunchtime Talk - Joe McCaffrey 11/7/25
YouTube video by Center for Philosophy of Science
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Yuval Nir @labnir.bsky.social · 10/09/2025
🚨 New paper alert! 🚨(1/6) Excited to share our work, out now in Science Advances We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings www.science.org/doi/10.1126/...
science.org
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
The locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening from sleep.
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Alessandro Gozzi @gozziale.bsky.social · 10/09/2025
Working link to the preprint 👇 www.biorxiv.org/content/10.1... See thread below for a looong explainer
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Daniel Lakens @lakens.bsky.social · 17/08/2025
Too often, I see people talk about a replication as if the first study has established something, and the replication study is a double-check. What people often fail to understand is that we do not do replication studies to *check* a finding, but to *establish* a finding. 1/x
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Sam Gershman @gershbrain.bsky.social · 13/07/2025
Thinking about writing a pop science book about the brain (“Your Brain on Everything”) where the big reveal is that all the brain names were randomized and I was actually talking about psychology the whole time.
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Takaki Komiyama @takakikomiyama.bsky.social · 20/06/2025
Our new paper is out in Science. We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change. Congrats to Bin for the great thesis, and the team! www.science.org/doi/10.1126/...
science.org
Cholinergic feedback for modality- and context-specific modulation of sensory representations
The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...
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allen institute @alleninstitute.org · 25/03/2025
Advances in neuroscience have yielded massive, rich datasets from various analysis techniques and modalities. 🧠📈 In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.
nature.com
Integrating multimodal data to understand cortical circuit architecture and function - Nature Neuroscience
This paper discusses how experimental and computational studies integrating multimodal data, such as RNA expression, connectivity and neural activity, are advancing our understanding of the architectu...
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Kevin Mitchell @wiringthebrain.bsky.social · 14/03/2025
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊
onlinelibrary.wiley.com
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience
The search for neural mechanisms of behaviour often relies on a synchronic, driving view of causation, where neural activity drives more neural activity, which eventually drives behaviour. The real c...
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