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Maximilian Hoffmann

@mh123.bsky.social
230 followers 1.8K following 53 posts

This is the worst I'll ever be

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Reposted by Maximilian Hoffmann
Benjamin Judkewitz @benjulab.bsky.social · 05/03/2026
First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...
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Chicago Reader @chicagoreader.com · 05/09/2025
The saxophonist, flutist, and composer has transformed the music over and over with Air, the Sextett, Very Very Circus, Zooid, and more. bit.ly/4mMB50X
bit.ly
Henry Threadgill turns jazz into a kaleidoscope of worlds and times - Chicago Reader
Saxophonist, flutist, and composer Henry Threadgill has transformed the music over and over with Air, the Sextett, Very Very Circus, Zooid, and more.
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 25/08/2025
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods! 📦 Ultrack — robust, scalable nD cell tracking 🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration Let’s dive in! 👇 www.nature.com/articles/s41... www.nature.com/articles/s41...
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Maximilian Hoffmann @mh123.bsky.social · 23/08/2025
The question, then, is whether you think the consequence of this suddenly happening to companies with a central position in the current economy will be really bad or just creative destruction as usual. I think the only thing Ed Zitron is saying is that it will be potentially quite bad...
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Maximilian Hoffmann @mh123.bsky.social · 23/08/2025
Why? There were clearly sustainable business models during the dotcom boom. The bubble still popped, if you call this the growth slows fine, but it seems euphemistic.
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columbo screenshots @columboscreens.bsky.social · 10/08/2025
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Ann Kennedy @antihebbiann.bsky.social · 24/07/2025
Interesting scheme for categorizing sensory systems- from Ching Kung, motivated by exploring sensory needs beginning with single-cell organisms.
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W. Brent Derry @wbderry.bsky.social · 16/07/2025
Model organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...
nature.com
Giant study finds a research field that’s mostly reproducible
Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.
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Britton Sauerbrei @brittonsauerbrei.bsky.social · 13/06/2025
Is it true you use only 10 bits / s of your brain? @andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in @natneuro.nature.com: www.nature.com/articles/s41...
sky.social
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Konrad Kording @kordinglab.bsky.social · 04/06/2025
Why human connectomes can probably not be useful for AI open.substack.com/pub/kording/...
open.substack.com
Lions and Dolphins can not make babies: Why human connectomes can probably not be useful for AI
How evolutionary thinking can make the debate more precise
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Maximilian Hoffmann @mh123.bsky.social · 05/06/2025
Because there is evidence that the brain harbours general cognitive mechanisms/systems/phenomena that are not immediately tied to specific sensory input?
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
but a lot of science operates on reproducibility and not the fact that many people in the room take the same measurement at the same time - seems to be a limiting condition to define this possibility as a necessity, if we largely operate without it.
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
Anything within the scientific endeavour is at least intersubjective - we need to agree on measurement outcomes that are presented to us individually as subjective experiences. It's true that you and me might not be able to prepare the same mental phenomenon,
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
I agree that our psychological theories are not mature, this is why they seem to be so susceptible to this kind of scepticism, but eventually you can bring down every scientific field in this way.
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
That you need auxiliary hypothesis is true in any scientific field. Accepting that mental phenomena exist seems quite pragmatic to me, because I have direct empirical access to mine.
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
to instruct a thought process, that leads to X red and X green flashes - report the number and order of these flashes. It sound crazy, but not impossible?
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
Is this not a measurement of a mental phenomenon. Why not? Because the motor sequence is an external cause? Because time is a physical outside reference? I can think of variants of this experiment, which do away with both, i.e. with a sophisticated psychological theory I might be ablet
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
I put you in a dark rook - 0 photons. You have a clock that is emitting a sound every X seconds. Now, I am teaching you a complicated motor sequence, that leads to two perceptible light flashes. I ask you to report the time between the two flashes - the time ends up being the same for everyone.
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Maximilian Hoffmann @mh123.bsky.social · 04/06/2025
I see. Just to understand, what, in your opinion, is the difference between my observation that pain exists and the observation that water freezes, when I cool it down to 0 deg C? Not saying there are the same, but curious what constitutes the difference.
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Charles Johnson @charles.littlegreenfootballs.com · 02/06/2025
Behind the Scenes: Brad Mehldau Records “Tomorrow Tomorrow” (feat. Daniel Rossen) #blogpost
littlegreenfootballs.com
Behind the Scenes: Brad Mehldau Records “Tomorrow Tomorrow” (feat. Daniel Rossen)
A behind-the-scenes look as Brad Mehldau records Elliott Smith's "Tomorrow Tomorrow," feat. Daniel Rossen, from his upcoming album, 'Ride into the Sun,' due August 29 on Nonesuch Records. Pre-order: bradmehldau.lnk.to Brad Mehldau – Piano Daniel Rossen – Lead Vocals, Acoustic Guitar Chris Thile – Mandolin, Backing Vocals Felix Moseholm – Acoustic Bass Matt Chamberlain – Drums Video by Matthew Edginton. Filmed at The Bunker Studio in Brooklyn, NY. #BradMehldau #ElliottSmith #BehindTheScenes
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Maximilian Hoffmann @mh123.bsky.social · 01/06/2025
That's a conjecture, right?
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Maximilian Hoffmann @mh123.bsky.social · 29/05/2025
Just curious: Where was the feature film comprehension achieved?
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Benjamin Judkewitz @benjulab.bsky.social · 12/05/2025
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching. A collaboration with @mh123.bsky.social 🚀 github.com/danionella/w...
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Katie Martin @katie0martin.ft.com · 15/05/2025
We made a film! About Michael Saylor and his amazing magic money machine. Take bitcoin, add mind-boggling amounts of financial engineering and a huge dose of very online crypto hype, and suddenly a lot of people are making a LOT of money www.youtube.com/watch?v=O_Wj...
youtube.com
Michael Saylor's $40bn bitcoin bet | FT Film
YouTube video by Financial Times
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Ida Momennejad @neuroai.bsky.social · 08/05/2025
Hot takes/kind reminders a) “the bitter lesson”’s promise of scale did not deliver wrt AI reasoning & higher cog functions—O3 hallucinates 2x more than O1 b) prediction is not understanding, hallucinating is worse c) gen AI could help neuroAI but following latest AI trends is not a paradigm shift
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Marisa Kabas @marisakabas.bsky.social · 25/04/2025
if you love the handbasket and want to keep it going strong, quote post this with why you’re a paid subscriber! i’m 200 away from a major goal. LFG. www.thehandbasket.co/upgrade
thehandbasket.co
The Handbasket
100% independent journalism by Marisa Kabas
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Maximilian Hoffmann @mh123.bsky.social · 17/04/2025
I am not sure why it is a foundation model, but I admit I haven't looked at the companion papers and what they do with the model there. Also not sure whether it's a good idea to treat the trial-average as the oracle model - the scores seem higher,but a desirable model should predict noise corr
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Michael Orger @daniobrain.bsky.social · 09/04/2025
It is hard to imagine a more prescient compilation than 1992's Artificial Intelligence, not just in terms of the careers of the contributing artists, but how the featured sounds have permeated popular culture over the last 30 years.
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Maximilian Hoffmann @mh123.bsky.social · 04/04/2025
It is of course painful that all this is gone.. Gottfried Benn on Berlin www.youtube.com/watch?v=c6R4...
youtube.com
Gottfried Benn im Interview 1956
YouTube video by Leah Herz
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Maximilian Hoffmann @mh123.bsky.social · 03/04/2025
I guess, we cannot possibly settle this dispute. 👍
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Maximilian Hoffmann @mh123.bsky.social · 03/04/2025
"Now coffee costs a little more" does seem far below Cohen poetics.
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Jonathan A. Michaels @jonathanamichaels.bsky.social · 30/03/2025
“Relevant computations happen in here too” Maimon on the limitations of pure connectivity data in the fly
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Maximilian Hoffmann @mh123.bsky.social · 28/03/2025
Funny, I think you are saying slightly different things. Are Alphafold and the other synbio models you are talking about really the kind of foundation models that the transmitter article proposes?
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Maximilian Hoffmann @mh123.bsky.social · 26/03/2025
Whether foundation models are the answer or not, what should be mentioned is that scaling up neuroscience is also an ... experimental problem, not just an archival one. I think the IBL experiments are maybe the most complex experiments that have been run at scale and they are mid-level complexity.
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Daryl Gohl @darylgohl.bsky.social · 22/03/2025
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
University of Minnesota Genomics Center Model Organism Sequencing Service Flyer. $25 for a 30x Drosophila genome.
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Paper Skygest Team @paper-feed.bsky.social · 10/03/2025
Hello world! We are building *personalized* feeds to help you make sense of research discussions on BlueSky! Pin our first feed below, which shows posts about papers from accounts you follow! Follow this account for more updates! bsky.app/profile/pape...
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Dan Davies @dsquareddigest.bsky.social · 13/03/2025
if anyone happens to be a physicist thinking about this offer, drop me a DM and I will give glowing character reference for one of the profs there who did an exchange to Exeter university a few years ago and is an absolutely top lad www.univ-amu.fr/fr/public/ac...
univ-amu.fr
Safe Place For Science : Aix Marseille Université prête à accueillir les scientifiques américains | Aix Marseille Université
Dans un contexte où certains scientifiques aux États-Unis peuvent se sentir menacés ou entravés dans leurs recherches, notre université annonce mettre en place le programme Safe Place For Science dédi...
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Henry Farrell @himself.bsky.social · 13/03/2025
In the newest issue of Science, meself, @alisongopnik.bsky.social, Cosma Shalizi and James Evans, "Large AI Models are Cultural and Social Technologies." More soon ... www.science.org/doi/10.1126/...
science.org
Large AI models are cultural and social technologies
Implications draw on the history of transformative information systems from the past
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Maximilian Hoffmann @mh123.bsky.social · 13/03/2025
The horseshoe theory, but for animal and AI consciousness
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Prevedel Lab @prevedel-lab.bsky.social · 20/02/2025
Thrilled and proud about our latest advancement in Brillouin microscopy - enabling true light-sheet like mechanical imaging at high throughput. Out today in @naturephotonics.bsky.social Congratulations Carlo! @carlobevilacqua.bsky.social rdcu.be/eaDiX
rdcu.be
Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer
Nature Photonics - A Fourier-transform imaging spectrometer enables two-dimensional spectral Brillouin imaging at a throughput of up to 40,000 spectra per second over a...
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John Burn-Murdoch @jburnmurdoch.ft.com · 24/02/2025
The youth gender divide is real and important, but it can mask the fact that the populist right is gaining ground among young women as well as young men in many countries (this was also true in the US). AfD tripled their vote share among 18-24 year old men, but the same was true of young women.
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Henry Farrell @himself.bsky.social · 23/02/2025
12. In the medium to longer term, perhaps developing some of the tools that it had begun to experiment with as an alternative to dollar payments in Trump's first term. Mutterings about the strategic value of separate European digital payments systems are likely to get a _lot_ louder.
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Karl Doemens @karldoemens.bsky.social · 19/02/2025
Aus. Vorbei. Zum ersten Mal in meinem Leben werde ich meine Stimme bei einer Bundestagswahl nicht abgeben können. Tausenden Auslandsdeutschen geht es genauso. Warum ich stocksauer bin. 👇👇👇 www.rnd.de/politik/bund...
rnd.de
Warum ich erstmals in meinem Leben keine Wahl habe
Unser US-Korrespondent hat wie Tausende andere Auslandsdeutsche in den Vereinigten Staaten bis heute seine Briefwahlunterlagen nicht erhalten. Deshalb kann er seine Stimme bei der Bundestagswahl nicht...
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Dr. Lucky Tran @luckytran.com · 18/02/2025
ACTION THIS WEDNESDAY: Researchers from New York universities are holding a rally to protest the funding cuts at Washington Square Park at 4 pm. This will be part of a national day of action, with rallies at HHS in DC and all around the country. RSVP HERE: docs.google.com/forms/d/e/1F...
ACADEMIC WORKERS UNITE!
DEFEND PUBLIC
RESEARCH FUNDING
JOIN THE NATIONAL DAY OF ACTION
FEBRUARY 19, 4:00PM
WASHINGTON SQUARE PARK
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Maximilian Hoffmann @mh123.bsky.social · 16/02/2025
please share!
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Maximilian Hoffmann @mh123.bsky.social · 15/02/2025
The synthetic IS3 dataset looks kind of out-of-distribution with respect to the real world....
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Maximilian Hoffmann @mh123.bsky.social · 15/02/2025
What are the best benchmarks and the SOTA on Sound Source Localization? arxiv.org/html/2409.06... seems to suggest that VGG-SS can be largely solved with video only?
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Rohan Alexander @rohanalexander.bsky.social · 14/02/2025
Happy to see Helen DeWitt finally getting her due.
Photo of books on a table with a sign "Timeless fiction" and the book "The Last Samurai" by Helen DeWitt on the table.
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James Manton @jamesdmanton.bsky.social · 12/02/2025
We present: Direct-view oblique plane microscopy www.biorxiv.org/content/10.1...
biorxiv.org
Direct-view oblique plane microscopy
The ability to rapidly image mesoscopic samples is critically important for many areas of biological research. Owing to its high throughput and gentle, volumetric imaging nature, light-sheet fluoresce...
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Colette Delawalla, PhD @cdelawalla.bsky.social · 09/02/2025
Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.
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