Abstract. The genome of the seasonal acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has a 12-nucleotide insertion that produced a furin cleava

Aligning and calling variants in a way that accounts for the sex chromosome complement of the sample will reduce false-positive variants and increase true-positive variants on the X and Y chromosomes.

Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...

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Some budding yeasts secrete killer toxins made by linear dsDNA plasmids located in the cytosol. The best-known example is the Kluyveromyces lactis toxin zymocin, which is encoded by a 9-kb killer plas...

A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable integrative genome-...