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Angela Oill

@angela-oill.bsky.social
26 followers 51 following 29 posts

Computational Scientist at the Translational Genomics Research Institute

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Angela Oill @angela-oill.bsky.social · 12/08/2026
Our (@nebanovich.bsky.social , @tgenresearch.bsky.social) most recent work with @kamancherla.bsky.social and Dr. Ravi Shah at VUMC is out in Nature CVR! www.nature.com/articles/s44... 1/14
nature.com
Dynamic cellular programs of human cardiac allograft rejection revealed by spatial transcriptomics - Nature Cardiovascular Research
Using spatial transcriptomics on longitudinal human cardiac biopsies, Amancherla, Oill and colleagues reveal marked cellular and molecular heterogeneity in transplanted hearts undergoing rejection, id...
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Reposted by Angela Oill
The American Journal of Human Genetics @ajhgnews.bsky.social · 19/03/2026
🧬 New today! 📄Best practices for improving alignment and variant calling on human sex chromosomes 🧑‍🤝‍🧑 @sexchrlab.bsky.social @angela-oill.bsky.social & co
cell.com
Best practices for improving alignment and variant calling on human sex chromosomes
Aligning and calling variants in a way that accounts for the sex chromosome complement of the sample will reduce false-positive variants and increase true-positive variants on the X and Y chromosomes.
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Reposted by Angela Oill
Science Magazine @science.org · 18/09/2025
Pastoralism remains central to survival in the Turkana of northwest Kenya, where heat and water scarcity pose constant challenges. New research uncovers the genetic signatures that underlie adaptation to arid living in this pastoralist community. Learn more this week: scim.ag/4nxcJbx
Young Turkana herders guide camels across Kenya’s arid landscape near Lake Turkana at sunset.
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Reposted by Angela Oill
Nick Banovich @nebanovich.bsky.social · 04/08/2025
So excited to share @saahimall.bsky.social just had her her first 1st author publication published in AJP lung! Huge accomplishment!!! This study wouldn't have been possible without the amazing @jensucre.bsky.social! journals.physiology.org/doi/abs/10.1...
journals.physiology.org
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity | American Journal of Physiology-Lung Cellular and Molecular Physiology | American Physiological So...
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
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Reposted by Angela Oill
Saahithi Mallapragada @saahimall.bsky.social · 06/06/2025
I am so excited to share our most recent work & my first big project as a graduate student! We leveraged spatial transcriptomics to study the cell-cell communication involved in human lung development. Here’s the full study: www.biorxiv.org/content/10.1... (1/17)
biorxiv.org
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While ...
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Reposted by Angela Oill
Nick Banovich @nebanovich.bsky.social · 05/06/2025
Congrats to @saahimall.bsky.social on her first study from her PhD! Also, science is always more fun when done with friends. Great to work as always with @jensucre.bsky.social and @jkropski.bsky.social!
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Melissa Wilson @sexchrlab.bsky.social · 07/05/2025
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth. Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives. www.biorxiv.org/content/10.1...
biorxiv.org
Best practices for improving alignment and variant calling on human sex chromosomes
Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...
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Reposted by Angela Oill
bioRxiv Genomics @biorxiv-genomic.bsky.social · 01/05/2025
Best practices for improving alignment and variant calling on human sex chromosomes www.biorxiv.org/content/10.1101/202…
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Reposted by Angela Oill
TGen @tgenresearch.bsky.social · 14/03/2025
Ever wondered if there was a way to know if an individual would accept or reject a transplant organ? In this preprint, @nebanovich.bsky.social used spatial transcriptomics to study heart transplant rejection. Check out the story from GenomeWeb & the preprint! www.genomeweb.com/gene-express...
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Angela Oill @angela-oill.bsky.social · 07/03/2025
I am excited to share our most recent work using spatial transcriptomics to uncover dynamic molecular responses to rejection in transplanted human hearts! 1/15 www.biorxiv.org/content/10.1...
biorxiv.org
Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomics
Allograft rejection following solid-organ transplantation is a major cause of graft dysfunction and mortality. Current approaches to diagnosis rely on histology, which exhibits wide diagnostic variabi...
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