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Mark McMullan

@mcmullan0.bsky.social
128 followers 86 following 15 posts

Evolutionary biologist -population genomics -wild-agricultural pathogen evolution, invasion and adaptation (Wheat & Beets)

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Reposted by Mark McMullan
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 24/09/2026
Lineage-specific positive selection on stress-response genes in wild wheat relatives www.biorxiv.org/content/10.64898/20…
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Daniel Croll @danielcroll.bsky.social · 04/09/2026
Our lab is looking for PhD students to join us in 2027 🎓🎉 The projects can be structured around our research directions: - Transposable element dynamics - Fungal pangenomics - ML/language model genomics applications - Pathogen adaptation More here pathogen-genomics.org ("Jobs") and please share! 🙏
pathogen-genomics.org
Evolutionary genomics of pathogens
Croll lab at University of Neuchatel. The lab of Daniel Croll wants to understand how pathogens evolve to cause disease. For this, we mainly focus on major crop pathogens to unravel mechanisms of rapi...
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Frank Menke @frankmenke.bsky.social · 02/07/2026
PhD project on Blast Fungus host pentration open in my #Proteomics group at @thesainsburylab.bsky.social for an October 2026 entry. Collaborative project with @talbotlabtsl.bsky.social. Deadline: 30th July. Open to Home Fee status applicants. biodtp.norwichresearchpark.ac.uk/projects/inv...
biodtp.norwichresearchpark.ac.uk
Investigating host penetration by the rice blast fungus (MENKE_S26DTP3) | Doctoral Training Partnership
MENKE_S26DTP3
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Earlham Institute @earlhaminst.bsky.social · 02/06/2026
📃 A new study in @fungal-ecology.bsky.social from @rowenahill.bsky.social uses GlobalFungi sequencing data to provide the first global assessment of Gaeumannomyces incidence, and reviews current understanding of host interactions and lifestyle.
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Host range and global distribution of Gaeumannomyces root fungi of cereal crops and wild grasses
Gaeumannomyces species (Magnaporthales, Ascomycota) occur worldwide as both pathogenic and commensal root-associates of cereal crops and wild grasses,…
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Reposted by Mark McMullan
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 29/04/2026
The genome of the Pacific acorn barnacle provides insights into the evolution of extremely large populations www.biorxiv.org/content/10.64898/20…
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Reposted by Mark McMullan
John Innes Centre @johninnescentre.bsky.social · 23/04/2026
ICYMI 📻 Catch up on yesterday’s BBC Radio 4 World at One programme - Sarah Montague caught up with JIC's Dr Elizabeth Orton to hear about the process she has refined to speed up ash seed germination, from years in nature down to a week in the lab (from 39:20): www.bbc.co.uk/sounds/play/...
Dr Elizabeth Orton holding germinating ash tree seeds on a plate, in the lab
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Reposted by Mark McMullan
Sadiye Hayta @sadiyehayta.bsky.social · 14/04/2026
We are seeking enthusiastic and motivated individual to join our Wheat Transformation and Gene Editing team. This is an exciting opportunity to work with cutting edge technologies at the forefront of crop science, contributing to innovative research in wheat improvement.
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Earlham Institute @earlhaminst.bsky.social · 09/04/2026
💡 PhD Blog: What's the importance of training during your first PhD year? Heading into her second-year, #PhD researcher Marine has shared her insights and experience of enhancing her skills and knowledge over the last 12 months, and practical advice for other students. Read here: buff.ly/xOhpq0S
Social graphic promoting the article "Training during your PhD: what my first year taught me." Background image shows a town in Czechia where the author recently undertook a training course.
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Toby Baril @tobybarilbio.bsky.social · 09/04/2026
🎉 EarlGrey ParTEA v0.1.6 is here! Huge thanks to everyone who's tried the pipeline and shared feedback — your suggestions directly shaped these new features. 🍵 #TEworldwide #transposableelements #bioinformatics #genomics
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Earlham Institute @earlhaminst.bsky.social · 02/04/2026
💬 "From machine learning courses at Earlham Institute, to field training at @rothamsted.bsky.social, the summer school in Bologna and the #genomics workshop in Czechia, each experience has helped prepare me for the challenges of my project." BLOG: What my first year of my #PhD studies taught me.
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Training during your PhD: what my first year of my PhD studies taught me.
PhD student Marine Folgoas reflects on the first year of her PhD and the important role training has played in developing her skills as a researcher.
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Reposted by Mark McMullan
Nick Talbot @talbotlabtsl.bsky.social · 22/03/2026
Some reflections on #Fungal26 This was a great meeting as always but set against some turbulent times of course, which meant many regular attendees were not present. This thread is mainly for them. However, the proportion of first-time attendees was very high and very international. #Fungal26 1/15
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Mark McMullan @mcmullan0.bsky.social · 17/03/2026
How does root invasion differ between endophyte & pathogen? We are interested in this dichotomy of expression in the most important root disease of wheat, take-all: Stealth vs SEVs Exceptional tenacity from Stella (looking for a PhD) and the team @earlhaminst.bsky.social @rothamsted.bsky.social 🙏
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Eva Stukenbrock @estukenbrock.bsky.social · 27/01/2026
What enables a fungus to invade a mammal host? @marco-guerreiro.bsky.social unravels signatures of translation adaptation among pathogenic and non-pathogenic species of Trichosporonales. See more: www.nature.com/articles/s41...
nature.com
Genomic and physiological signatures of adaptation in pathogenic fungi - Nature Communications
Emerging fungal pathogens have detrimental impacts on crops, animals, and humans, however little is known about their transition to a pathogenic lifestyle. This study demonstrates that the transition ...
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Reposted by Mark McMullan
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 22/01/2026
Distribution of Gene Tree Topologies with Duplication, Loss, and Coalescence www.biorxiv.org/content/10.64898/20…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 15/01/2026
Mutualistic microbes drive niche expansion yet constrain diversification www.biorxiv.org/content/10.64898/20…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 14/01/2026
Gene function predicts divergence across molecular levels www.biorxiv.org/content/10.64898/20…
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Anne Roulin @anneroulin.bsky.social · 05/01/2026
Have we been overstating the role of transposable elements in adaptation to local or rapidly changing environmental conditions? Happy to share my (somewhat unpopular?) opinion paper on this matter: www.sciencedirect.com/science/arti... Thanks to those who already shared the link!
sciencedirect.com
Blinded by the lights? Re-examining the adaptive role of transposable elements in plants with population genomics
Transposable elements (TEs) are ubiquitous components of the genome whose mobility can be triggered by environmental stress and influenced by genotype…
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Mark McMullan @mcmullan0.bsky.social · 17/12/2025
www.theguardian.com/environment/...
theguardian.com
‘Magical’ galaxy frogs disappear after reports of photographers destroying their habitats
Researcher in Kerala rainforest sounds alarm after being told frogs had died after being handled by humans
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Charlotte Wright @charlottewright.bsky.social · 10/12/2025
Are you excited about pangenomics? If so, join us in Edinburgh on 8-9th June to discuss the latest methods & insights from using these approaches across biodiversity! More details here: royalsociety.org/science-even... Organised together with @henrylnorth.bsky.social & @joanameier.bsky.social!
royalsociety.org
Pangenomics transforms evolutionary biology | Royal Society
This Theo Murphy meeting organised by Dr Joana Meier, Dr Henry North and Dr Charlotte Wright, will showcase cutting-edge pangenome tools, applied uses of pangenomes which are transforming health and a...
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Manjeet Dhull @manjeet-dhull786.bsky.social · 01/07/2025
Spent last week at the microscope 🔬✨, and seeing arbuscular mycorrhizal fungi up close for the first time—hyphae, arbuscules, vesicles—was absolutely mind-blowing. Small but mighty partners of plant roots 🌿. Sharing a few of my favourite shots. #Mycorrhiza #fungi
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Daniel Croll @danielcroll.bsky.social · 12/11/2025
Big congratulations @tobybarilbio.bsky.social! Please check out and share our final version of the transposon mobilization work in a fungal pathogen - out now in Nature Communications www.nature.com/articles/s41...
nature.com
Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
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Rowena Hill @rowenahill.bsky.social · 07/11/2025
A quick tutorial blog on a method I haven't seen before to plot gene gain/loss from e.g. CAFE5 across a phylogeny - and clearly shows I always have fungi on the mind 🤓🍄 #rstats #ggplot2 rowena-h.github.io/data-visuali...
rowena-h.github.io
Mushroom plots to visualise gain and loss on a phylogenetic tree
A tutorial on how to visualise gene gain and loss on a phylogenetic tree
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Reposted by Mark McMullan
Daniel Croll @danielcroll.bsky.social · 29/10/2025
@tobybarilbio.bsky.social and I are very excited to release MycoMobilome! A very extensive effort to discover, QC and annotate TEs across the fungal kingdom. 👉 Ready-to-use for your own genome with a simple tutorial! 👉 Metadata about TEs discovered in your genome! 👉 Contribute and get recognition!
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Roshani Badgami @roshanib.bsky.social · 28/10/2025
Super excited to see our bioRxiv paper out! It furthers our understanding of an FHB resistance locus in timopheevii with some DON resistance too!
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Earlham Institute @earlhaminst.bsky.social · 23/10/2025
PHD: What does an ‘optimal’ community of #bacteria and #fungi look like for #pathogen suppression? That's a key question to explore in this fully-funded #PhDproject with @neilhall.bsky.social, @mcmullan0.bsky.social and @rowenahill.bsky.social at the Earlham Institute.
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Combatting wheat take-all disease with in-field and synthetic microbial communities
4-year Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD
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Earlham Institute @earlhaminst.bsky.social · 21/10/2025
PHD: Are you interested in gene regulation, #immune function, or tech development? We have a fully-funded 4-year #PhDproject with @whatchamacaulay.bsky.social at the Earlham Institute and @tiagocluis.bsky.social at Imperial looking at niche cell–cell communication. ➡️ buff.ly/M7u6thJ
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Exploring niche cell–cell communication through alternative splicing
4-year Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD
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Team Thomma @teamthomma.bsky.social · 14/10/2025
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
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Dan Gibbs 🌱🧬 @djgibbs.bsky.social · 14/10/2025
We are advertising a PhD project investigating a cellular mechanism that ensures protein quality control during mRNA translation in plants. Please get in touch on here or via email if you are interested and I can provide further details! Lab website: sites.google.com/site/danielg...
sites.google.com
Daniel Gibbs Lab
Welcome to the lab website of Professor Daniel Gibbs @ University of Birmingham
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Leonie Moyle @speciationlab.bsky.social · 14/10/2025
Great new postdoc fellowship for foundational plant research. If you’re into genetics and genomics of plant reproductive evolution or adaptive convergence (incl in the cool and charismatic nightshades!) I’d be happy to talk about possible projects! www.simonsfoundation.org/grant/simons...
simonsfoundation.org
Simons Postdoctoral Fellowships in Plant Biology
Simons Postdoctoral Fellowships in Plant Biology on Simons Foundation
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Mark McMullan @mcmullan0.bsky.social · 13/10/2025
PhD studentship Come help us understand the wheat rhizosphere at the Earlham Institute 🦠 Working at the interface of fungal antagonists & pathogens (@rowenahill.bsky.social @neilhall.bsky.social ), host genetic diversity (Simon Griffiths -JIC) and bacterial community diversity (Jacob Malone -JIC)
earlham.ac.uk
Combatting wheat take-all disease with in-field and synthetic microbial communities
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Eva Stukenbrock @estukenbrock.bsky.social · 12/10/2025
Professorship in plant genetics. The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See: www.berufungen.uni-kiel.de/de/dateien/o...
berufungen.uni-kiel.de
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Earlham Institute @earlhaminst.bsky.social · 04/10/2025
🍄 Today marks #UKFungusDay where we get to celebrate the weird and wonderful kingdom of Fungi. As well as being fundamental to a healthy ecosystem, and often fascinating to spot, #Fungi can be devastating to plant and animal populations.
A common bracket fungus on the side of a treeXylaria fungus growing out of a tree stumpSmall cap mushrooms surrounded by fallen leaves and grass in a woodland
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Rowena Hill @rowenahill.bsky.social · 16/09/2025
Was a pleasure to contribute a small part to this massive WGS effort of Kew's fungarium! @estergaya.bsky.social @rbgkew.bsky.social Check out the paper @newphyt.bsky.social 👉 doi.org/10.1111/nph.70472
A map of the world with countries coloured by how many accessions they have in Kew's fungarium, and pie charts for each country indicating how many accessions have had DNA extracted and their genomes sequenced
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Nature Plants @natplants.nature.com · 03/09/2025
New OA Article: "Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions" rdcu.be/eDWJI With News & Views: "Diversity favoured: heterozygosity attracts crossovers" rdcu.be/eDWKQ
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Rowena Hill @rowenahill.bsky.social · 27/08/2025
It was a delight to have Guillaume Delhaye and Torda Varga (@rbgkew.bsky.social) at @earlhaminst.bsky.social last week, talking to a packed Norwich Research Park audience about mushroom-forming and mycorrhizal fungi from molecule to ecosystem! 🍄🧬🌳 @neilhall.bsky.social @norwichmicro.bsky.social
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Nature Plants @natplants.nature.com · 18/08/2025
Our editors write: - Wheat immunity: "Unlocking yellow rust resistance" rdcu.be/eBbSJ about rdcu.be/eBbT0 - Auxin signalling: "A rack for the hook" rdcu.be/eBbTg about www.pnas.org/doi/10.1073/...
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Evolution Letters @evolletters.bsky.social · 31/07/2025
How predictably does complex trait adaptation proceed over space and time in wild populations? doi.org/10.1093/evle... Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al. 📷: Dr. Rush Dhillon
Figure showing the experimental overview as a graphic. Remaining alt text taken from the figure caption in the paper: (A) we sampled flies from six wild orchard populations ranging from Homestead, FL, to Lancaster, MA, and established isofemale lines in the laboratory. (B) We returned to a focal orchard in Media, PA, at early- and late-season timepoints and collected flies to capture evolutionary patterns following winter and summer conditions. (C) We then seeded outdoor mesocosms (N = 9) with an outbred population originating from early-season collections in Media, PA, and sampled flies at the end of summer (mid-season) and fall (late-season) to determine if seasonal patterns are recapitulated in experimental populations controlled for migration, drift, and cryptic population structure. (D) Across each wild or experimental context, we sampled flies, established lines in the lab, completed common garden treatment to remove environmental effects, and scored females for abdominal pigmentation. We also conducted pooled DNA sequencing on additional flies sampled from each population to map genomic patterns for candidate pigmentation SNPs.
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Rob Waterhouse @rmwaterhouse.bsky.social · 29/07/2025
Advances in computational methods for inferring networks from #genome-scale data and guidelines for deriving biological insights from #phylogenetic networks www.pnas.org/doi/10.1073/...
pnas.org
Phylogenetic networks empower biodiversity research | PNAS
Reticulate evolution has long been recognized as a key mechanism that contributes to genetic and trait diversity. With the widespread availability ...
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Mark McMullan @mcmullan0.bsky.social · 26/07/2025
www.nature.com/articles/s41... Really nice. Especially nice RIP result linked to ancestral sex hypotheses. Which then links nicely to plastic genomic regions and adaptation in the face of asexual reproduction.
nature.com
Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution - Nature Communications
Giant transposons, known as ‘Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions crucial for infection in a plant pathogeni...
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Emily Josephs @emjo.bsky.social · 12/06/2025
Hey, Miles' @milesroberts.bsky.social beautiful paper showing that sequence diversity missed by standard methods contributes to Lewontin's paradox is officially published in @evolletters.bsky.social. academic.oup.com/evlett/advan...
academic.oup.com
k-mer-based diversity scales with population size proxies more than nucleotide diversity in a meta-analysis of 98 plant species
Abstract. A key prediction of neutral theory is that the level of genetic diversity in a population should scale with population size. However, as was note
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Earlham Institute @earlhaminst.bsky.social · 13/06/2025
Keen to work in #PlantSciences? 🌿 Applications are open for a new John Innes Foundation Internship with Dr Carolina Grandellis at the Earlham Biofoundry. 🧬 You'll work on #bioengineering approaches for plant sciences, utilising high-throughput platforms at the Earlham Institute.
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John Innes Foundation Internship in Plant Science
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Genetics Society of America @genetics-gsa.bsky.social · 11/06/2025
Using an alignment-free k-mer-based phylogenetic method, @rowenahill.bsky.social, @mcmullan0.bsky.social, and the team found that relationships between entire Starships differed from those inferred from captain genes. Read more about Starships fungal transposons in #G3journal: buff.ly/vxOe5oq
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estergaya.bsky.social @estergaya.bsky.social · 11/06/2025
In case you want to know more about Kew’s Fungarium and our sequencing work! #Fungi #museomics @rbgkew.bsky.social www.newscientist.com/video/248375...
newscientist.com
Unlocking genetic secrets of the world's most vital fungi collection
Fungi underpin all life on Earth, yet it is estimated that more than 95 per cent of fungal species remain undiscovered. Holding over 1.25 million dried specimens, the Fungarium at Royal Botanic Garden...
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Rowena Hill @rowenahill.bsky.social · 04/06/2025
Our paper on phylogenetics of fungal Starship TEs is now on the cover of the June issue of Genetics @genetics-gsa.bsky.social 🙂 academic.oup.com/genetics/iss... @mcmullan0.bsky.social @earlhaminst.bsky.social @rothamsted.bsky.social
Cover for the June issue of the journal Genetics, with an abstract illustration in the background showing starships flying through space trailing DNA sequences that meet in the bottom right corner to form a circular phylogenetic tree
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Joe Hanly @hanliconius.bsky.social · 30/05/2025
While helping out on a cool genomics project recently, I came to realise I’d been taught a pretty big inaccuracy about the events that occur at fertilization. I suspect that almost everyone reading this has the same misapprehension, so let’s do some learning together: 1/
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DSW ISP @dsw-isp.bsky.social · 16/05/2025
If you missed the @wheatgenome.bsky.social webinar yesterday with @simongriff.bsky.social "Breeding: Why we need to start over again" watch it here: www.youtube.com/watch?v=X0kZ...
youtube.com
Breeding: Why we need to start all over again
YouTube video by International Wheat Genome Sequencing Consortium
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Earlham Institute @earlhaminst.bsky.social · 15/05/2025
💬 “When we looked at the replication start sites we’d identified, we discovered only 20% of them had been reported previously. The majority were newly discovered with this approach." 📃 Researchers use ultra #longreads to reveal where #DNAreplication starts in the #humangenome: buff.ly/pQWGasr
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Starting point of DNA replication mystery solved
The question of where DNA replication starts in the human genome has finally been addressed, with the conclusion it is largely random.
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Mark McMullan @mcmullan0.bsky.social · 15/05/2025
Kmer based phylogenetic methods like Mashtree (@lskatz.github.io), are really powerful for difficult to align and repetitive regions including TEs, Integrative and conjugative elements & Starships etc. Really nice work from @rowenahill.bsky.social and thanks to collaborators @rothamsted.bsky.social
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Mark McMullan @mcmullan0.bsky.social · 30/04/2025
Thanks for posting @reviewcommons.org If you're interested you can also find the reviewed version here: doi.org/10.7554/eLif... Really keen to get people's perspectives on the population genetics of reservoirs, and what they tell us about variation associated with emergent crop pathogens.
doi.org
Developing a crop- wild-reservoir pathogen system to understand pathogen evolution and emergence
Evidence for those pathogen genes selected specifically for success on crops.
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