iiinova — where your digital self keeps evolving

Reposted by Maurice Lee

Reto Fiolka @retof.bsky.social · 12/02/2025

The self-driving multiscale microscope from @daetwylerstephan.bsky.social is out. It can image an entire zebrafish embryo longitudinally and follow a volume of interest over time with high resolution. We used it to study cancer-immune cell interactions. www.nature.com/articles/s41...

nature.com

Imaging of cellular dynamics from a whole organism to subcellular scale with self-driving, multiscale microscopy

Nature Methods - A self-driving multiresolution light-sheet microscope enables the simultaneous observation and quantification of cellular and subcellular dynamics in the context of intact and...

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Maurice Lee @mauriceylee.bsky.social · 03/02/2025

Goodbye Mr Snouty. I had a lot of fun working with you. It has been a blast. Hopefully the next scientist/engineer who works with you will enjoy the process too.🥹

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Reposted by Maurice Lee

BWJones @bwjones.bsky.social · 14/01/2025

Science bio-imaging question: What platform are people liking for confocal / super-resolution imaging these days? Leica? Zeiss? Olympus? Nikon? Other?

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Maurice Lee @mauriceylee.bsky.social · 13/01/2025

Hello science friends on bluesky! After many years of doing molecular biophysics and optics/microscopy, I just want to share that I'm leaving science and academia next month. I don't have concrete plans for my next step yet so I might just take a break for a while but we shall see how things go.

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Reposted by Maurice Lee

Christophe 🔬 Leterrier @christlet.bsky.social · 20/11/2024

Also in today's preprint trawling: imaging at depth is difficult, so let's just... squish cells? arxiv.org/abs/2411.12656

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Reposted by Maurice Lee

Alex Donovan @apadonovan.bsky.social · 18/11/2024

Does anyone know any good publications/databases to find non-coding variant loci for neurodevelopmental disorders? (anything, but particularly disorders of brain size if possible)

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Maurice Lee @mauriceylee.bsky.social · 15/11/2024

Caring for your friends in science means lending them your neutral density filter wheel to see if it will help to alleviate their microscope problems

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Maurice Lee @mauriceylee.bsky.social · 14/11/2024

please don't do this. but i do have objectives that are broken and beyond repair. and i also do have immersion oil in the lab. and i also do have an optical table. hmmm

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Maurice Lee @mauriceylee.bsky.social · 14/11/2024

Hello everyone! So many of you have followed me over the past several days. I'm guessing most are interested in my science research work (i.e., fluorescence microscopy, image analysis, spatial transcriptomics). So I decided to wind down my bird app account and slowly post a little more on Bluesky.

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Reposted by Maurice Lee

Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 06/11/2024

Made a starter pack for microscopy and image analysis - please (self-)nominate additions! go.bsky.app/Nwa91pC

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Maurice Lee @mauriceylee.bsky.social · 09/11/2023

I had the opportunity to conduct a hands-on workshop on basic optical alignment today! Zesheng and Alex, from Dr Liang Kaicheng's group, joined me in the optics lab where we covered the basics such as "walking" the laser beam, collimating lasers, and checking back reflections!

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Maurice Lee @mauriceylee.bsky.social · 01/11/2023

The 21st Annual Advanced Imaging Methods Workshop is a 3-day event focused on new and emerging optical microscopy techniques and their applications hosted by the CRL Molecular Imaging Center at UC Berkeley on 23-25 Jan 2024. www.eventbrite.com/e/21st-annua...

eventbrite.com

21st Annual Advanced Imaging Methods Workshop

The Advanced Imaging Methods Workshop is a 3-day event focused on new and emerging optical microscopy techniques and their applications.

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Maurice Lee @mauriceylee.bsky.social · 04/10/2023

I think these are my favorite forever stamps ever!🖤🤍♥️💚🩵🧡

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Maurice Lee @mauriceylee.bsky.social · 19/08/2023

We have started to work on 3D spatial transcriptomics of the whole larval zebrafish brain and I'm excited to share an image that we recently acquired in the lab! Every bright spot or blob represents the RNA molecules that we've labelled and imaged! The image below is 1750*1050 microns.

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Maurice Lee @mauriceylee.bsky.social · 07/08/2023

Yes! I feel like I'm working on a technology of the future now. "we foresee that spatial omics will likely evolve toward three-dimensional spatial omics (operating on whole organs or even organisms)" www.science.org/doi/10.1126/science…

science.org

Just a moment...

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Maurice Lee @mauriceylee.bsky.social · 04/08/2023

I'm still amazed that my Pixel 7 can see stars with the astrophotography mode amidst all that light pollution in Singapore.

This is a photo of the night sky. The contrast has been heavily adjusted such that the stars can still be visible as white spots in a black night sky despite the light pollution from the city below. We can see a few cranes at a construction site at the bottom of the photo

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Maurice Lee @mauriceylee.bsky.social · 03/08/2023

We finally got a micrometer screw gauge (with a ratchet) to measure the thicknesses of our #1.5 glass coverslips to see how close they are to the specified 0.170 mm thickness with micron precision! The first two were 0.183 and 0.212 mm thick.🤷🏻‍♂️

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Maurice Lee @mauriceylee.bsky.social · 31/07/2023

Soviet scientist Flyorov had found that American/British scientists, who wrote on nuclear developments before mid-1940, had stopped publishing. www.washingtonpost.com/archive/poli…

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Maurice Lee @mauriceylee.bsky.social · 30/07/2023

Got a chance to enjoy the hot weather and see some touristy sights in Singapore today!

This is a photo of an urban scenery. There is a blue sky with fluffy white clouds. There are modern looking buildings in the background. There is also a foot bridge with dozens of people. There are green trees and bougainvilla bushes too

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Reposted by Maurice Lee

Izzy Jayasinghe @ijayas.bsky.social · 26/07/2023

For newly arrived Bluesky life scientists, I would recommend the Micro-Nano-Bio feed. This still needs optimizing but it pulls in any posts with the following keywords: 🔬 microscopy "super resolution" "single molecule" "localization microscopy" SMLM 🦠 nanotechnology

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Reposted by Maurice Lee

Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 28/07/2023

Made a feed tracking "bioimaging", "microscopy", and "bioimage analysis" (I hope to make something fancier later that can take more than 3 terms, but "perfect" is the enemy of "done" and I'm super grateful track.goodfeeds.co makes it easy to make one). Please share if you like those terms!

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