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matteomazzocca.bsky.social

@matteomazzocca.bsky.social
90 followers 61 following 5 posts

Postdoc @andersshansen.bsky.social Lab @ MIT | @acscan.bsky.social fellow | PhD @davidemazza.bsky.social Lab @ Vita-Salute San Raffaele University | 3D genome, TFs, gene regulation

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Anders Sejr Hansen @andersshansen.bsky.social · 16/09/2026
. @matteomazzocca.bsky.social and I were fortunate to contribute single molecule imaging of chromatin dynamics to this beautiful study from K Alimenti and M Blower on SAF-A/HNRNPU:
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varshram.bsky.social @varshram.bsky.social · 07/08/2026
Happy to share my first preprint! We looked at how the 3D genome changes during red blood cell differentiation, especially at erythroid CREs. It was fun to work on this collab with many wonderful people from the @andersshansen.bsky.social and @bloodgenes.bsky.social labs esp. Chun-Jie.
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Darío Lupiáñez @dariloops.bsky.social · 21/07/2026
🚨 Job Alert - Please share 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! ✅ 4 years fully funded PhD position 💻🧪 Experimental or computational backgrounds welcome 👇 Details below #PhDPosition #PhDOpportunity #AcademicJobs
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Anders Sejr Hansen @andersshansen.bsky.social · 22/06/2026
(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack: Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)? A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): www.biorxiv.org/content/10.6...
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Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · 13/05/2026
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇
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Anders Sejr Hansen @andersshansen.bsky.social · 05/05/2026
(1/n) Super excited to share that our preprint is out today in @natsmb.nature.com with a new name "Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types" and more than 2x more data: www.nature.com/articles/s41... See also MIT News news.mit.edu/2026/how-chr...
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David Brückner @davidbrueckner.bsky.social · 14/03/2026
How do pairs of DNA loci - such as enhancers and promoters - find each other inside the nucleus? 🤔 Most models assume the random forces driving locus motion are independent in space New preprint by @janniharju.bsky.social: this assumption fails in living cells 🧵 www.biorxiv.org/content/10.6...
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Tineke Lenstra @tinekelenstra.bsky.social · 12/03/2026
Ever wondered how a eukaryotic transcription factor finds its specific DNA motif in the vast genome? In this preprint, we directly measured the dynamics of this search process in living cells, revealing a cooperative mechanism mediated by disordered regions. 1/10 doi.org/10.64898/202...
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Davide Mazza @davidemazza.bsky.social · 26/02/2026
🧵 I’m very happy to share a new preprint from the @samuzambrano.bsky.social group and ours — a project driven by @emabiong.bsky.social, a PhD student bold enough to tackle a question at the interface of our two expertises: how the biological oscillators p53 and NF-κB talk to each other.
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Luca Giorgetti lab @FMI @lucagiorgetti.bsky.social · 24/09/2025
Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication. www.biorxiv.org/content/10.1... A🧵👇
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matteomazzocca.bsky.social @matteomazzocca.bsky.social · 14/05/2025
1/ Super excited to share my first preprint from @andersshansen.bsky.social Lab! We used MINFLUX to track chromatin (H2B-Halo and Fbn2 locus) at an unprecedented 200 μs, then combined it with SPT to span μs-minutes (H2B) or SPT & Super-Res Live-Cell Imaging (SRLCI) to span μs-hours (Fbn2)
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