iiinova — where your digital self keeps evolving

Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 16/09/2026

Our new preprint presents a #deeplearning model by @pmouseli.bsky.social that predicts evoked muscle pain. Coolest finding: the model performs better when trained on controls, rather than in the chronic pain cohort. This has genuine consequences for biomarker development. tinyurl.com/42tmbjj3

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 03/09/2026

Have your say on the development of an international consensus on a comprehensive standardized protocol and core reporting outcomes for QST in youth! lnkd.in/gF-YRhi3 If you have general questions about this project, you can contact me by emailing dondaniel.ocay@childrens.harvard.edu.

redcap.tch.harvard.edu

RESEARCH INFORMATION SHEET

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Reposted by Massi(e)h Moayedi — مسیح مویدی

Réseau québécois de recherche sur la douleur @rqrd-qprn.bsky.social · 01/09/2026

🤝 Pain research is stronger when it is shaped with people who live with pain. During International #PainAwarenessMonth, let’s highlight the importance of bringing their lived experience, needs and priorities into #PainResearch. 🔬

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 26/08/2026

We had 2 control groups: One that got no stimulation but had the thermode on the skin, and another that received stimulation 1°C above baseline. This let to an important methodological observation: secondary hyperalgesia is prone to response bias. People report a change even without stimulation

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 26/08/2026

We also show 2 cool new findings: 1. that innocuous stimulation (the thermal grill) causes sensitization in responders and nonresponders 2. that moderate cold stimuli (7°C) cause sensitization

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 26/08/2026

📣 Check out the latest paper from our lab out now in @pnas.org 📣 We show that nociceptive sensitization can occur in the absence of pain stimulation. We use the thermal grill illusion, and show that nonresponders show greater central sensitization (secondary hyperalgesia) than responders.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 25/08/2026

@iasp.bsky.social’s PRF is hosting a debate tomorrow between Wani Woo & Kai Karos on Pain Biomarkers. More information here: painresearchforum.org/event/join-u...

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 20/08/2026

The @iasp.bsky.social elections for president-elect, secretary, and councillors is now open. If you’re a member in good standing, please vote! These elections do have meaningful consequences in IASP funding decisions, programs and priorities. Help us shape IASP to better serve the pain community.

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Katie Matthews, PhD @katieocean.bsky.social · 14/07/2026

Wow. Published in May in The Lancet. Look at those numbers of fabricated references per 10,000 articles in PubMed. The urge to publish is overcoming the urge to, I dunno, discover and learn things? #AI #medsky 🧪 www.thelancet.com/journals/lan...

thelancet.com

Fabricated citations: an audit across 2·5 million biomedical papers

Scientific literature depends on the integrity of its references. Each reference implicitly asserts that a verifiable source exists and supports the claims being made. When references point to non-exi...

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 08/07/2026

Learning that Canada is spending $2.6B on 12 rocket launchers. Worth noting that this exceeds Canada’s Health Research budget ($1.4B) in 25/26 (which is largely stagnant). 12 rocket launchers get almost double than life changing research. 🤯

Screenshot form the Toronto Star that says:

“That doesn't mean the door is closed on procuring military hardware from the U.S., he added, noting recent decisions to buy more than a dozen HIMARS artillery systems from U.S. company Lockheed Martin for $2.6 billion, and up to 16 P-8 Poseidon "multi-mission" planes from American firm Boeing for more than $5 billion.”

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International Association for the Study of Pain (IASP) @iasp.bsky.social · 01/07/2026

Emiko Senba, MD, PhD, will present her Plenary Lecture, Exercise Therapy for Chronic Pain: Basic Science and Clinical Practice, at the #2026WorldCongressonPain. Register to attend her lecture and 100s of other sessions this October in Bangkok: bit.ly/4e0fErL #IASP2026

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 22/06/2026

I’m really looking forward to the #2026WorldCongressonPain! The @iasp.bsky.social meeting is always full of amazing content & good fun! The meeting is 26–30 October 2026, in Bangkok, Thailand. Check out more info on #IASP2026 at bit.ly/43NwEuZ

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US Association for the Study of Pain @usasp.bsky.social · 26/04/2026

Save the date for the Canadian Pain Society's Annual Scientific Meeting in Quebec City! Attendees will find the latest advances in pain science, clinical care, and innovation, and valuable networking opportunities. Canadian Pain Society's 46th Annual Scientific Meeting Date: April 29 - May 2, 2026

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 25/04/2026

Want to learn about what some of are thinking about chronic #pain? Gillian Best interviewed pain researchers, including Melanie Noel, @richellemychasiuk.bsky.social, @simonbeggslab.bsky.social, @tedpricethepainguy.bsky.social, @jeffreymogil.bsky.social, @daspainbrain.bsky.social, me, & many more.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 20/04/2026

This work was a collaboration with @laurenatlas.bsky.social & Dave Finn (@universityofgalway.bsky.social), and led by S. Alisona Fatemi & Spencer Abssy. Stay tuned we have parts 2 & 3 coming out soon!

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PAIN @painthejournal.bsky.social · 20/04/2026

@massih.bsky.social et al. find that baseline circulating endocannabinoid ligand concentrations are associated with individual differences in pressure pain threshold, but not thermal thresholds/tolerance, or temporal summation of pain. Learn more in #PAIN bit.ly/4tEJzdL

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 18/04/2026

Not sure why it says 2024. It’s definitely 2026!

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 18/04/2026

Check out the oitstanding submissions for the @canadianpain.bsky.social’s Art Awards. CPS Members can vote for their top choice. www.canadianpainsociety.ca/previoussubm... Looking forward to seeing you all in Quebec City in 2 weeks! #CanPain26 #CPS_ASM26 #🇨🇦PainSociety

canadianpainsociety.ca

2024 Art Awards | The Canadian Pain Society

Created to better understand pain through an artistic lens. With a new theme each year, we showcase submitted artwork from a variety of mediums to promote scientific curiosity and build a gallery of...

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 20/03/2026

My brilliant sister @yasmoayedi.bsky.social has published some awesome work about how smartwatches can help save lives of folks with heart failure. Check it out

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paul evan bunce, md @paulbuncemd.bsky.social · 17/03/2026

is there a better day to decide to learn the irish language? here is a cbc story on those who have decided to take up the challenge.

cbc.ca

An bhfuil Gaeilge agat? Why the Irish language is ‘having a moment’ | CBC Radio

Do you speak Irish? A growing number of people are picking up Ireland’s native language, both inside the country and here in Canada.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 17/03/2026

For St-Patrick’s day, @padraigmoran.bsky.social produced a piece on the resurgence of the Irish language for CBC’s the Current. Check it out on cbc.ca/listen. On at 9:05 local time on the app. Otherwise should be available on the show feed all day.

cbc.ca

Live Radio | CBC Listen

Radio One and CBC Music

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 04/03/2026

@aircanada.bsky.social’s new safety video is one large Disney parks ad. Kinda gross, given the tariffs and threats from the US. Maybe read the room, AC.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 01/03/2026

What a lovely (and remarkably productive) week in London.

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Eiko Fried @eikofried.bsky.social · 27/02/2026

Great new paper led by @bringmannlaura.bsky.social, highlight the need to collect qualitative data in ESM / EMA research. #PsychSciSky 🧪 www.nature.com/articles/s44...

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

This could be interpreted as an unmasking effect: in the absence of a robust opioidergic response, the contribution of eCBs becomes apparent. Let us know what you think!

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

• When increases in beta-endorphin levels are high, then eCBs do not contribute to placebo analgesia • When there is little increase in placebo-induced beta-endorphin levels, then eCBs contribute to placebo analgesia.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

When we modeled endocannabinoids and beta-endorphins together, we found that beta-endorphins moderated the effect of FAAH substrates.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

Changes in FAAH substrates were associated with individual differences in placebo analgesia. There was no effect of 2-AG

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

Surprisingly, placebo-test-related changes in circulating beta-endorphins alone were not associated with individual differences in placebo analgesia.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

Baseline FAAH substrates and 2-AG did not predict individual differences in placebo analgesia. We also measured circulating beta-endorphins. Baseline beta-endorphins did not predict placebo analgesia.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

We first investigated whether circulating endocannabinoids were associated with individual differences in placebo analgesia. As AEA, OEA, and PEA are all FAAH substrates, and circulating levels are collinear, we computed a composite measure with PCA - “FAAH substrates”

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

There are 2 endocannabinoid ligands: anandamide (AEA) and 2-arachidonoylglycerol. There are also related N-acylethanolamines (OEA, PEA). These are also FAAH substrates - the enzyme that breaks down AEA. Evidence shows that those with functional variants of FAAH have reduced pain sensitivity.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

And we elicited robust placebo analgesia, but with individual differences - both responders and non-responders

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

Let me walk you through the findings: First, we use a standard placebo analgesia paradigm

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 27/02/2026

Check out our latest paper: The Contribution of endocannabinoids to placebo analgesia www.biorxiv.org/content/10.6... This is an ongoing collaboration with David Finn & @laurenatlas.bsky.social Take away: beta-endorphins gate the contributions of endocannabinoids to placebo analgesia.

biorxiv.org

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Charley Sheets (disappointment in humanity arc) @rcsheets.net · 02/01/2026

Replace any x.com link with xcancel.com and the same rest of the URL. Try it out. No need for an account, nor to add to X’s traffic.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 24/12/2025

Legitimate question for scientists: What’s a reasonable window for a desk reject? I’ve had hours to weeks… I just had one that took 21 days at a journal with a pretty high IF. I think that’s way too long, but wanted to get others’ impression.

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Reposted by Massi(e)h Moayedi — مسیح مویدی

Dalhousie University @dalhousie.bsky.social · 19/12/2025

Dalhousie University is hiring. We’re recruiting up to 30 tenure and tenure-track faculty supported by Canada Global Impact+ Research Talent Initiative and a $1.7B federal investment. Curious about building your next chapter in Canada? Apply by Jan. 19: www.dal.ca/research-recruitment

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Andrew Pruszynski @andpru.bsky.social · 18/12/2025

If you're (1) into nhp neurophysiology and/or biological motor control, (2) a foreign big shot and (3) interested in moving here, please reach out -- this new program looks extremely attractive (min. $8M over 8y)! www.uwo.ca/research/can...

uwo.ca

Canada-Impact-Plus - Research - Western University

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Siri Leknes @sirileknes.bsky.social · 18/12/2025

Mind blown! Did you know about EMERGE, this amazing resource on self-report scales? All items listed and psychometric properties assessed, in ONE place & user friendly to boot emerge.ucsd.edu/emerge-searc...

emerge.ucsd.edu

Emerge Search – EMERGE

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Lauren Atlas @laurenatlas.bsky.social · 15/12/2025

I am so excited to share our newest preprint, inspired by @tinalonsdorf.bsky.social, “A multiverse approach to heat-evoked skin conductance analysis: Evaluating the influence of analytic pipeline on associations between skin conductance and pain osf.io/preprints/ps...

osf.io

OSF

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Marcin Szczot @szczotml.bsky.social · 14/12/2025

Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8 www.biorxiv.org/content/10.6...

biorxiv.org

Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling

Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....

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Olga Nesterova @onestpress.onestnetwork.com · 14/12/2025

The hero who disarmed one of the terrorists in Sydney turned out to be 43-year-old Ahmed al-Ahmed — a fruit shop owner and father of two. He was shot twice and is currently in hospital. He is scheduled to undergo surgery. He had no experience with weapons of any kind.

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 12/12/2025

Canada is finally getting high speed rail (maybe?) But the route cuts out Kingston and leaves out London & Windsor. These could easily become engines of industry & exchange. What a missed opportunity! #Canada #CanPoli #politics #highspeedrail

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Jibran Khokhar @drjkhokhar.bsky.social · 10/12/2025

I’m offering the same! Have helped 8 ECRs and multiple CERC candidates (including one that will hopefully be successful) in the past year make the move to Canada! DM me with your questions or we can set up a zoom call!

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