TRIM21/Ro52 assembles proinflammatory immune complexes.

A new study has found that a protein TRIM21 linked to Sjögren’s disease may be fuelling the condition in an unexpected way. Researchers at the Kennedy Institute of Rheumatology have discovered that du...

Sami Barkal is a 5th year medical student at Oxford's Kennedy Institute of Rheumatology and is a visiting student from Witten/Herdecke University in Germany. In this student story, Sami details his

Data can easily be manipulated to show causation that doesn’t exist.

Living well and fighting back in a time of terrors

T cells induced by personalized pancreatic-cancer vaccines last for years.

Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system’s own record of antigen ...

Lifesaving treatment and prevention programs for tuberculosis, malaria, H.I.V. and other diseases cannot access funds to continue work.

The administration of U.S. President Donald Trump has instructed federal health agencies to pause all external communications, such as health advisories, weekly scientific reports, updates to websites and social media posts, the Washington Post reported on Tuesday, citing a dozen current and former officials and sources.

An immunogen engineered by computational and structure-based methods activated diverse B cell precursors and induced rare mutations in mouse models.

The seasonal influenza vaccine contains strains of viruses from distinct subtypes that are grown independently and then combined. However, most individuals exhibit a more robust response to one of the...

Objective To prospectively investigate the associations between dark, milk, and total chocolate consumption and risk of type 2 diabetes (T2D) in three US cohorts. Design Prospective cohort studies. ...

A podcast on the host defense systems that protect against disease

Autoantibody immune responses could contribute to acute and post-COVID-19 symptoms. Here, the authors describe longitudinal autoantibody responses in a cohort of healthcare workers and hospitalised CO...