iiinova — where your digital self keeps evolving

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WESTPA Software @westpasoftware.bsky.social · 11/12/2025

WESTPA fans: two new JCTC papers just landed! Great work from Michael Grabe and JC Gumbart. 👇

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Adrian Mulholland @adrianmulholla1.bsky.social · 30/08/2025

Come and work with us in Bristol Chemistry, ranked #1 in the UK for research. We’re seeking outstanding candidates in: Engineering biology Synthetic biology Chemical biology Biophysics or biophysical tools Biocatalysis www.bristol.ac.uk/jobs/find/de...

bristol.ac.uk

Details | Working at Bristol | University of Bristol

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Jenna Norton @jenna-m-norton.bsky.social · 24/08/2025

This is a good watch. So much potentially impactful science is being stopped for no good reason.

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Gabriela K Popescu @popstarlab.bsky.social · 25/07/2025

Did you know about the BPS Bridging Funds Program? If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting! I am grateful to the @biophysicalsoc.bsky.social for supporting our members! www.biophysics.org/2026meeting/...

biophysics.org

BPS2026 Travel Awards | Biophysical Society

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Eric Topol @erictopol.bsky.social · 06/07/2025

Summary Table of the massive defunding of biomedical research in the United States www.nytimes.com/interactive/...

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Joseph Q Jarvis MD MSPH @drjqjarvis.bsky.social · 30/06/2025

Out of the 356 drugs that were approved by the FDA from 2010-2019, NIH funding contributed to 354 of them, totaling $187 billion, only 2 were privately funded. From the NYTimes www.nytimes.com/interactive/...

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Science Magazine @science.org · 02/07/2025

Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90

scim.ag

Exclusive: Famed protein structure competition nears end as NIH grant money runs out

Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold

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Vaughn Cooper @vscooper.micropopbio.org · 05/06/2025

This article says all you need to know about why basic science is the lifeblood of innovation. It’s the long game but there remains no substitute. Also a favorite example of @jeremymberg.bsky.social The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...

newyorker.com

The Radical Development of an Entirely New Painkiller

The opioid crisis has made it even more urgent to come up with novel approaches to treating suffering. Finally there’s something effective.

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Jeremy Berg @jeremymberg.bsky.social · 24/04/2025

ATTENTION: NSF GRANT RECIPIENTS We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years. 1/n

media.tenor.com

a cartoon of a man holding a frying pan and a spoon with red alert written above him

ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him

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Rommie Amaro @rommieamaro.bsky.social · 26/03/2025

✨ Check out @mackevinbraza.bsky.social 's new work on full length APOBEC3B, which shows how the NTD modulates active site opening in the CTD Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs pubs.acs.org/doi/10.1021/...

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Miranda-Quintana group @groupquintana.bsky.social · 10/02/2025

Great collaboration with @ltchong.bsky.social on pathway ensemble clustering. 🌟SHINE🌟 is out in @biorxiv-biophys.bsky.social : www.biorxiv.org/content/10.1..., and of course @lexinc.bsky.social got it in #MDANCE as well: github.com/mqcomplab/MD...

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Rommie Amaro @rommieamaro.bsky.social · 13/03/2025

A behemoth effort from @fionachembot.bsky.social in which she does amazing science (showing how VOCs reshape allosteric pathways) while also making the SARS2 spike color palette match her fish Dorry 😍🫠 www.biorxiv.org/content/10.1...

spike protein domains and mutations in VOCs

Fiona's tang fish named Dorry matches the spike colors

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Lillian Chong @ltchong.bsky.social · 20/03/2025

@westpasoftware.bsky.social is partnering with @mdanalysis.bsky.social for Google Summer of Code this year. Please help spread the word!

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MIT Department of Chemistry @mitchemistry.bsky.social · 14/11/2024

Check out this excellent profile of Catherine Drennan (@drennanlab.bsky.social), Professor of Chemistry and Biology, which was recently published in PNAS: www.pnas.org/doi/10.1073/...

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Rommie Amaro @rommieamaro.bsky.social · 09/12/2024

For those following the @prof-ajay-jain.bsky.social /Cleaves/ @wpwalters.bsky.social preprint re: DiffDock @gcorso.bsky.social I have read some of the back-&-forth between the author groups As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵

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Marta Filizola @martafilizola.bsky.social · 08/12/2024

pubmed.ncbi.nlm.nih.gov/39643640/ “while AlphaFold3 shows improved performance over AlphaFold2 in predicting overall GPCR backbone architecture, significant discrepancies persist in ligand-binding poses, particularly for ions, peptides, and proteins.”

pubmed.ncbi.nlm.nih.gov

AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors - PubMed

G protein-coupled receptors (GPCRs) are critical drug targets involved in numerous physiological processes, yet many of their structures remain unresolved due to inherent flexibility and diverse ligan...

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Arvind Ramanathan @ramanathanlab.bsky.social · 26/11/2024

Really fortunate to have had the honor of being featured as part of NVIDIA SC24 special address by Jensen Huang and Ian Buck. This summarizes a lot of the work that is ongoing in the group highlighting the role of LLMs, multi modality and generative AI. youtu.be/eKzNKxWUeCE

youtu.be

NVIDIA SC24 Special Address

YouTube video by NVIDIA

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 11/12/2024

Check out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯 www.nature.com/articles/s41...

nature.com

Discovery and engineering of the antibody response to a prominent skin commensal - Nature

Nature - Discovery and engineering of the antibody response to a prominent skin commensal

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