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Lorne Genome Conference, Australia @lornegenome.bsky.social · 24/09/2026

Abstract submission now open for Lorne Genome, held Sunday, February 14, 2027 - Wednesday, February 17, 2027 in the Lorne Theatre! Submit by Friday 13 November 2026 Prizes available for students, mid career and early career researchers. web.cvent.com/event/e57907...

web.cvent.com

Submissions - LORNE GENOME CONFERENCE 2027

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/09/2026

@lornegenome.bsky.social 2027 features Dr Michael Beer from Johns Hopkins University. He uses machine learning algorithms to discover how DNA encodes cell-specific enhancer activity. His work focuses on dynamic models of enhancer activation in cell state transitions and dysregulation in cancer.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 09/09/2026

Join us for the 48th Lorne Genome Conference, taking place from 14–17 February 2027 at the historic Lorne Theatre Lorne Genome 2027 will showcase an exciting scientific program coverin all things genomic. Early bird registration open now and abstract submission coming soon! lnkd.in/geaQ3xNE

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 30/04/2026

Lorne Genome 2027 will be held 14 to 17th February in Lorne Australia. Our invited speakers will include Karen Arndt, Neil Brockdorff, Laura Banaszynski and Fides Zenk.

Lorne Genome 2027 Poster: 14 to 17th February, at Lorne Australia. Background shows the coast off Lorne. Invited speakers include Karen Arndt, Neil Brockdorff, Laura Banaszynski and Fides Zenk.

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Reposted by Lorne Genome Conference, Australia

MACSYS @macsys.bsky.social · 20/02/2026

Honoured to have a member of our Intl Scientific Advisory Board in Australia this week. Prof Brenda Andrews from the Univ of Toronto (pictured right) delivered an invited talk at the Lorne Genome Conference and caught up with our Chief Investigator Traude Beilharz, president of the Conference Board.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 18/02/2026

That's a wrap for Lorne Genome 2026! Thanks to all the speakers for fascinating talks, poster presenters for hot of the press science, trade for making the experiments possible and of course all the attendees for great discussion. See you next year!

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 18/02/2026

Congratulations to winners of the Lorne Genome Best Student Poster Prizes: Jessica Hawes, Sarah Berent, David Neville, Sandeep Kum and Andrea Daner!

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Reposted by Lorne Genome Conference, Australia

Martin Smith @martinalexsmith.bsky.social · 18/02/2026

Could @lornegenome.bsky.social be the MOST Aussie genomics conference?

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Reposted by Lorne Genome Conference, Australia

Steve Turner @sjturn.bsky.social · 17/02/2026

Last day of #Lornegenome. A great venue, cool talks and discussions. Learnt about diversification of mammalian genomes, inheritance of mutations and impact of mutagens, how TFs direct chromatin organisation and so much more. New collaborations, new projects, can’t wait til next year

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 18/02/2026

2026 Winner of the Lorne Genome Julian Wells Medal: Christine Wells (no relation!) @stemcellsystems.bsky.social congratulations, well deserved!!

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Reposted by Lorne Genome Conference, Australia

Dr Andrew Lonsdale @lonsbio.bsky.social · 17/02/2026

Almost literally too late, but here is a feed for BlueSky to collate #LorneGenome posts that blends mentions of Lorne + Genome along with posts from @lornegenome.bsky.social Should still work next year though! bsky.app/profile/did:...

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Journeying back in time with Liran Carmel: reconstructing Neanderthal methylation. Found regions with different methylation to humans: genes that affect the face and voice.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Jennifer Zenker showing how pluripotent cells have unique microtubule organisation and its asymmetries direct fate decisions

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Reposted by Lorne Genome Conference, Australia

Kate Quinlan @katequinlan.bsky.social · 17/02/2026

We’ve been spoiled with lovely weather & quality science at @lornegenome.bsky.social this year, continuing this morning with Session 11 (Novel Approaches to Study the Genome) & then the Julian Wells Medallist presentation. Hope everyone has rested up after the dinner! See you 9am! #LorneGenome2026

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Lorne Genome Conference dinner with a few party crashers

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Jenny Tung: Marrying evolutionary ecology and evolutionary genetics to link traits leading to differential survival with changes in allele frequency across generations using the cutest model organism: the meerkat

media.tenor.com

a group of meerkats are standing next to each other and looking at the camera

ALT: a group of meerkats are standing next to each other and looking at the camera

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Hazuki Takahashi: are RNA DNA 🧬 interactions cell type specific in humans? Develop RADICL-seq to map RNA-DNA interactions. Capture both cis and trans interactions, showing cell type specific interactions

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Transposable elements move DNA around genome, creating new genes BUT also a mutagen causing disease ☯️ Keith Slotkin has harnessed this mechanism to target DNA inserts to 🌿🫛 genomes. Have used synthetic biology to improve targeting from industry standard of 1% to >99% while reducing off target sites

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

90% Small Cell Lung Cancer🫁 is immune silent and evades immunotherapy , but there is plasticity between immune active / silent types. Marian Burr seeks to regulate this transition for improved SCLC survival.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Austen Ganley does a random genome project: puts A.thaliana DNA into human cells. Gets transcription that is independent of A. Thailana genes.

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Reposted by Lorne Genome Conference, Australia

Dr Andrew Lonsdale @lonsbio.bsky.social · 17/02/2026

Can only tag @antobeck.bsky.social here on BlueSky to say that the #Illumina coffee cart is once again the quiet hero of #LorneGenome

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

@jennbrophy.bsky.social gives a beautiful talk uncovering the regulation of lateral root development, creating tools to engineer root branches 🌱

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Brenda Andrews: yeast 🥪 a fantastic systemic genetics, all viable deletion mutants are available. Using to map genetic interactions ➡️ link phenotype to genotype

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Thanks to Roche for bringing out @joepdel.bsky.social from Hartwig Medical to share his work using Roche-SBX for Paired Tumour–Normal Whole Genome Sequencing on their cohorts.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Up now Hongpei Li @singmolsci.bsky.social, winner of #lornegenome best student abstract! Telling us how p16 and polycomb interact to cause irreversible growth arrest and cell cycle exit.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Peter Cockerill's first Lorne Genome talk was in 1993! Back telling us about how chromatin priming allows faster reactivation of immune response genes in Memory T Cells.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 17/02/2026

Alexey Terskikh @perkinsinstitute.bsky.social shows us how epigentic change in the inner hair cells of the cochlear occur in a spatial fashion and is predictive of age.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Petra Hajkova @imperialcollegeldn.bsky.social germ cells are depleted for lamins compared to somatic cells but pericentric heterochromatin still anchors to the periphery via H3K9me, in a similar fashion to ancestral 3D organisation that occurs in c. elegans.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Ferdinand von Meyenn @imps-ethzurich.bsky.social is there metabolic memory im adipose tissue? Sampling from patients post bariatric surgery retain an obesity signature in their adipose cells post weight loss.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Bing Zhu kicking off today by taking us through the mysteries of heterochromatin.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Good morning Lorne! Hope you are enjoying another beautiful morning before we begin with our Epigentics and Chromatin session at 9am

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Reposted by Lorne Genome Conference, Australia

Kate Quinlan @katequinlan.bsky.social · 16/02/2026

It’s another beautiful morning in Lorne, with blue skies & kangaroos. Highs of 33 degrees & afternoon rain/thunderstorms are predicted, but it will be cool & dry in the @lornegenome.bsky.social Heritage Ballroom for Session 7: Epigenetics & Chromatin at 9am. Looking forward to it! #LorneGenome2026

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Directed cell fate reprogamming is holy grail for regenerative medicine. Katherine Zyner created Refate to identify small molecules that can be used to convert cells between states. www.biorxiv.org/content/10.1...

biorxiv.org

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Upon birth we have to switch from g to b globin 🩸 for effective oxygen uptake. Mitchell Weiss takes us through developmental regulation of globin genes and how insights have led to dev of therapeutic gene therapies for haemoglobinopathies. Challenge: personalised therapies are expensive

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Michael Gandal genetic architecture of ASD and schizophrenia: GWAS studies have discovered 100s of loci influencing both disorders, current challenge is how do we interpret their role in disease? Colocalisation of psychiatric loci w cis EQTLs only explains 20%. What about isoforms??

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Matthew Stephens introduces us to the wild world of matrix factorisation MF. Genomics has big datasets we want to simplify. What makes factors more interpretable? PCA can give different results to (non neg) NMF because it can have neg weights, but this makes PCA factors less interpretable than NMF.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Somatic mutations can drive disease, but hard to distinguish from technical error. Rhys Gillman introduces SCARCE: Single-Cell Analysis of Rare Clonal Events which blends scDNA seq with surface markers to find clonal variants in specific cell types www.biorxiv.org/content/10.1101/2025.10.30.685685v1

biorxiv.org

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Andrew Lonsdale @petermaccc.bsky.social showcases LemonSplice 🍋 to try to answer the question of what does the mess of splice junctions 🧩 even mean? Shiny interface that visualises, quantifies novelty and links to published findings.

Andrew Lonsdale presenting at Lorne Genome 2026

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Spatial transcriptomics methods can struggle to scale on large datasets, or miss biological structure. Nora Liu @saigenci.bsky.social introduces DOMINO, a diffusion optimised contrastive learning framework for spatial domain detection, an accurate and scalable ST method.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Woo Jun Shim from UQ uses epigenomes of epigentic marks to create Epigenetic Comodulated Programs (EpiCops) to help provide functional interpretation of GWAS hits.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Waruni Abeysekera @wehi-research.bsky.social shows gene sets are contain intergene corrélation but gene permutation testing dusrupts this, inflating results, including in Fast GSEA (Gene Set Enrichment Analysis). Describes CAMERA which controls the false discovery rate better.

is.to

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 16/02/2026

Tongtong Wang @petermaccc.bsky.social kicking off the computational Biology parallel session introducing EmbryoRadar, a machine learning model to identify developmental programs reactivated in cancer.

Tongtong Wang presenting at Lorne Genome 2026

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 15/02/2026

The neurodevelopmental disorder Tatton-Brown-Rahman Syndrome is caused by defects in DNMT3A, but critical brain development continues after birth. Hannah Vanyai @wehi-research.bsky.social explores whether anti sense oligonucleotide intervention in the post natal window can reduce symptoms.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 15/02/2026

Why do some obese people remain metabolically healthy and others develop disease? Isabel Reinisch @ethz.ch teases out genetic factors separating these groups.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 15/02/2026

Alex Hewitt @utas.edu.au takes #lornegenome through genetic drivers of glaucoma, making use of large biobanks, showing high predictive rates for glaucoma polygenic risk scores compared to other common diseases.

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Lorne Genome Conference, Australia @lornegenome.bsky.social · 15/02/2026

Duncan Odom takes #lornegenome on a wild ride through lesion segregation showing repair of DNA damage can be strand resolved.

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Chris Wells @stemcellsystems.bsky.social · 15/02/2026

Choose your own adventure @lornegenome.bsky.social Duncan Odom www.lifepi-hd.com/duncan-odom asks if we want greatest hits or new hot stuff - role on hot stuff!

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Kate Quinlan @katequinlan.bsky.social · 15/02/2026

Good morning @lornegenome.bsky.social delegates! In case you missed watching the sunrise on the beach this morning (with galahs!), I’m happy to report that today we have a forecast of blue skies, highs of 31 degrees & some great science, kicking off with @odomlab.bsky.social at 9am. #LorneGenome2026

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