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Juan C López-Rodríguez

@lopix8.bsky.social
74 followers 179 following 4 posts

PhD in Biochemistry | Postdoc at USP-CEU @allerbiomics.bsky.social | #MAIT #Immunology #asthma #allergies

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Reposted by Juan C López-Rodríguez
Journal of Experimental Medicine @jem.org · 20/08/2026
CD1d remodels the tumor-infiltrating myeloid populations controlling anti-tumor immunity. New study from Lauren Evans, Maria Conde Poole, Patricia Barral @barrallab.bsky.social @kingscollegelondon.bsky.social @crick.ac.uk and colleagues: rupress.org/jem/article/... #BreastCancer #TumorImmunology
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Reposted by Juan C López-Rodríguez
Waggoner Lab @labwaggoner.bsky.social · 14/08/2026
CD1d remodels the tumor-infiltrating myeloid populations controlling antitumor immunity @jem.org @barrallab.bsky.social @kingscollegelondon.bsky.social @crick.ac.uk rupress.org/jem/article/...
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Reposted by Juan C López-Rodríguez
Journal of Experimental Medicine @jem.org · 13/08/2026
Evans et al. @barrallab.bsky.social identify CD1d as a key regulator of myeloid cell diversity in #BreastCancer. CD1d targeting reshapes tumor immune infiltrates, suppresses tumor growth, & enhances #immunotherapy efficacy, suggesting an actionable pathway for treatment. rupress.org/jem/article/...
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Reposted by Juan C López-Rodríguez
Barral Lab @barrallab.bsky.social · 13/08/2026
Our latest paper is out! We went back to our favourite molecule, CD1d, and explored its functions in myeloid cells in tumours. Amazing work from Lauren and Maria, and many thanks to our collaborators and funders @breastcancernow.bsky.social @cruk-cityoflondon.bsky.social doi.org/10.1084/jem....
doi.org
CD1d remodels the tumor-infiltrating myeloid populations controlling antitumor immunity
Evans et al. identify CD1d as a key regulator of myeloid cell diversity in breast cancer. CD1d targeting reshapes tumor immune infiltrates, suppresses tumo
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Reposted by Juan C López-Rodríguez
Andy Hogan @andyhogan82.bsky.social · 12/08/2026
Delighted to share @eimearrryan.bsky.social latest paper out now in @jimmunol.bsky.social showing Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines academic.oup.com/jimmunol/art...
academic.oup.com
Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines
Abstract. Mucosal-associated invariant T (MAIT) cells express a semi-invariant T cell receptor (TCR) that recognizes bacterial-derived antigens presented o
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Reposted by Juan C López-Rodríguez
PRIDE Database @pride-ebi.bsky.social · 16/07/2026
PAD000044 🚨 The Olink® Target 48 Cytokine panel is derived from human circulating MAIT cells that were exposed to a combination of different stimuli, including IL-33 and IL-12p70. 🚨 New dataset alert! 🚨
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Reposted by Juan C López-Rodríguez
Waggoner Lab @labwaggoner.bsky.social · 12/07/2026
Synergistic TCR-independent action of IL-33 and IL-12 drive a potent IFNγ secretory program in human circulating MAIT cells with immunomodulatory properties @frontiersin.bsky.social www.frontiersin.org/journals/imm...
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 10/07/2026
🎉 Our latest paper is out in #FrontiersInImmunology! Our study shows that IL33 and IL12 drive a potent TCR-independent activation program in human MAIT cells, promoting IFNγ production, metabolic reprogramming and immunomodulatory functions that shape monocyte responses. 🔬🧬 doi.org/10.3389/fimm...
doi.org
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Reposted by Juan C López-Rodríguez
Immunity @cp-immunity.bsky.social · 10/06/2026
dlvr.it
MAIT cells egress the thymus at several maturation stages with selective capacity to seed different tissues
MAIT cells acquire effector-memory and tissue-residency programs in the thymus. Paiva et al. demonstrate that MAIT cells can be selected by epithelial cells and egress the thymus at several developmental stages with subset-specific tissue tropisms and that during colitis, thymic MAIT17 cells expand and are directed to the gut.
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Reposted by Juan C López-Rodríguez
Bibiana Rojas @biobiiana.bsky.social · 23/10/2025
What makes PhD students happy? Good supervision www.nature.com/articles/d41...
nature.com
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
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Reposted by Juan C López-Rodríguez
Waggoner Lab @labwaggoner.bsky.social · 16/12/2025
Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood @jem.org @scripps.edu @mikerobe.bsky.social rupress.org/jem/article-...
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Reposted by Juan C López-Rodríguez
The Rejoin EU Party @therejoineuparty.com · 16/12/2025
📢 This petition reflects what many of us already feel about Brexit’s impact. If you haven’t signed yet, here’s the link: petition.parliament.uk/petitions/74...
petition.parliament.uk
Petition: Apply to Rejoin the EU as soon as possible to increase growth in the UK
We believe Brexit's not working. The OBR judges that the UK economy is smaller and trade is weaker because of Brexit, and it will just get worse. 10 years after the Brexit vote, let's apply to rejoin ...
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Reposted by Juan C López-Rodríguez
Journal of Experimental Medicine @jem.org · 10/12/2025
To celebrate today's presentation of the #NobelPrize in Physiology or Medicine to Mary E. Brunkow, Frederick J. Ramsdell and Shimon Sakaguchi, we present a special collection highlighting important JEM studies by Shimon Sakaguchi on regulatory T (Treg) cells. 👉 rupress.org/jem/collecti...
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 03/12/2025
Thrilled to share our new SIAF-led work (Dr.Milena Sokolowska) with @allerbiomics.bsky.social & @hureinasofia.bsky.social (Dr.Berta Ruiz), revealing Phe as a metabolic checkpoint in Th2 cells. Amazing teamwork between SIAF, Córdoba and CEU! Check it! doi.org/10.1016/j.xc... #Immunology #Metabolism
cell.com
L-Phenylalanine is a metabolic checkpoint of human Th2 cells
Kulkarni et al. show that L-phenylalanine reprograms energy metabolism and restrains growth and differentiation of human Th2 cells. Patients with severe allergic diseases feature reduced L-phenylalani...
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 12/05/2025
🧠Today, we share at #ScienceShareMondays, an EAACI position paper by Tomás Chivato & @eizq.bsky.social, based on the role of Telemedicine in allergy, discussing benefits, limitations and ethical considerations. Read more here! onlinelibrary.wiley.com/doi/10.1111/... #Telemedicine #Allergy
onlinelibrary.wiley.com
Telemedicine with special focus on allergic diseases and asthma—Status 2022: An EAACI position paper
Efficacious, effective and efficient communication between healthcare professionals (HCP) and patients is essential to achieve a successful therapeutic alliance. Telemedicine (TM) has been used for d....
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 12/03/2025
Today we started at #WIRM2025 with a short talk from our PI María Escribese. She gave a brilliant presentation on how mAB treatment in allergic asthma and immune metabolism are linked. #Asthma #Immumometabolism #Immunology
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 14/03/2025
Today Maria Isabel Delgado (@midelgadodolset.bsky.social) gave a talk about the immunomodulatory role of platelets based on a multi-omics analysis. #WIRM2025 #Immunology #Platelets #OmicsSciences
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 15/03/2025
On the last day of #WIRM2025 today, Nuria Contreras (@nurcgomez97.bsky.social) presented our multi-omics data on Severe Olive-Allergic Patients Treated with Dupilumab. #Immunology #Dupilumab #SevereAllergy #Allergy #OmicSciences
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 06/03/2025
Today we start our account dedicated to #scientificresearch on #allergy from the Faculty of Medicine at San Pablo CEU University. We will post our ongoing projects, findings and the highlights of our research. Make sure to follow us to be updated on our work and know more about the world of allergy!
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 12/03/2025
Later that day, Juan Carlos Lopez (@lopix8.bsky.social) will talk about our most recent findings on the role of MAIT cells in Th2 inflammation. #Allergy #MAITcells #Immunology
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 12/03/2025
Followed by Juan Carlos Lopez (@lopix8.bsky.social) who shared our latest insights on the role of MAIT cells in Th2 inflammation. #Allergy #MAITcells #Immunology
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Reposted by Juan C López-Rodríguez
Allerbiomics @allerbiomics.bsky.social · 14/03/2025
Congratulations to Juan Carlos Lopez (@lopix8.bsky.social) for winning the #BioLegend Workshop Prize at #WIRM2025! 🎉 We are honored to see our work on #MAITcells contributing to the field of #Allergy. Excited for what’s to come!
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