Sign in

Laurie Parker

@llparker100.bsky.social
88 followers 102 following 56 posts

Chemical biLOLogist, proteomics enthusiast. MN 🔬🧪🧫 views expressed are my personal ones.

PostsRepliesMedia
Reposted by Laurie Parker
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 30/07/2026
We already do this and companies who want them are happy to pay for PhD student interns. Why do precious and limited NSF funds need to be deployed for this? Most PhD student pursue industry jobs anyways - that has always been true. Use NSF funds to support basic science that industry wont support!
728698
Reposted by Laurie Parker
Reese Richardson @reeserichardson.bsky.social · 05/06/2026
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)
18590367
Reposted by Laurie Parker
shauna @goldengateblond.bsky.social · 07/05/2026
happy 9th anniversary to the day we watched Zendaya fall madly in love with Tom Holland in real-time
163127104091
Reposted by Laurie Parker
Gina Baucom @gbaucom.bsky.social · 14/04/2026
😱 Super excited to be named as a Guggenheim Fellow!! 😱
4928530
Reposted by Laurie Parker
Mina Kimes @minakimes.bsky.social · 10/04/2026
I can't stop laughing at this post. It's perfect.
A guy asking ChatGPT to review a series of fart sound effects and getting a serious kiss ass response that calls it atmospheric
886275436167
Reposted by Laurie Parker
I-75 Scientist @flscitriguy.bsky.social · 24/03/2026
On NOFOs and funding. grants.nih.gov/news-events/...
grants.nih.gov
NIH’s Path to a Simpler Funding Opportunity Landscape | Grants & Funding
099
Reposted by Laurie Parker
snackerü @snackeru.bsky.social · 18/03/2026
It has gone under the radar, but the University of Minnesota has selected a new brand tagline: "Leave a Future" Ummm ... it kind of makes the old "Driven to Discover" tagline look like a work of genius. I've got another tagline to run by them: "Uff da" umarcomm.umn.edu/brand
University of Minnesota

Leave a Future
12441842
Reposted by Laurie Parker
Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social · 17/02/2026
We posted a biorxiv preprint on structural bioinformatics, AlphaFold modeling & machine learning on predicting specificity of E3 ligase ring domains for different E2 enzymes. 1/4 Preprint: www.biorxiv.org/content/10.6... Models/data (UbiqCore website): dunbrack.fccc.edu/ubiqcore
15327
Reposted by Laurie Parker
Melissa Nadia Viviana 🐸 @resistrebelrevolt.net · 18/01/2026
Today, Minneapolis had their annual Powderhorn Art Sled Rally. A community organized event that this time featured de-Icer sleds and bowling pins named for world leaders. A very Minnesotan way to protest ICE. 😍🙌🏻
23821265
Reposted by Laurie Parker
Science Magazine @science.org · 10/08/2025
The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. Learn more:
scim.ag
Delving into LLM-assisted writing in biomedical publications through excess vocabulary
Large language models (LLMs) like ChatGPT can generate and revise text with human-level performance. These models come with clear limitations, can produce inaccurate information, and reinforce existing biases.
28330
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 08/08/2025
www.nih.gov/about-nih/ni...
nih.gov
Statement on the retirement of Dr. Noni Byrnes
Dr. Byrnes has served as CSR Director since 2019.
276
Reposted by Laurie Parker
Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social · 08/08/2025
Nice containerization of AlphaFold, Boltz, and Chai, and calculation of metrics (including our ipSAE score for protein-protein interactions). www.biorxiv.org/content/10.1...
04511
Reposted by Laurie Parker
Jeremy Berg @jeremymberg.bsky.social · 07/08/2025
Well, this is a huge Executive Order power grab... www.whitehouse.gov/presidential... 1/3
whitehouse.gov
Improving Oversight of Federal Grantmaking
By the authority vested in me as President by the Constitution and the laws of the United States of America, and to improve the process of Federal
52430240
Reposted by Laurie Parker
Science Magazine @science.org · 31/07/2025
The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
scim.ag
With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency
Republicans on spending committee push back against proposed reorganization and overhead cuts
010030
Reposted by Laurie Parker
Gregg Gonsalves @gregggonsalves.bsky.social · 30/07/2025
Russell Vought wanted to shut down all extramural grants from NIH in this current fiscal year, putting stop to ALL research across the US. Someone in the White House had better sense. But Vought is a dangerous man, who will stop at nothing to destroy science in America. www.wsj.com/politics/pol...
wsj.com
Trump Administration Scraps Effort to Pause Health-Research Funding
The administration halted and then restarted billions in new research grants flowing from the National Institutes of Health.
10340142
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 29/07/2025
This NIH grant Multi-Year Funding ploy really makes you wonder what equally obscure and equally harmful stuff Vought is advancing across all the other functions of federal government, doesn’t it?
310525
Reposted by Laurie Parker
Gregg Gonsalves @gregggonsalves.bsky.social · 29/07/2025
This is just so screwed up.
32313
Reposted by Laurie Parker
Science Magazine @science.org · 28/07/2025
Researchers’ chances of winning a grant from the National Institutes of Health have dropped under a new policy. scim.ag/4f7uew2
scim.ag
Odds of winning NIH grants plummet as new funding policy and spending delays bite
Funding multiyear grants up front will sharply cut number of investigators receiving awards
14732
Reposted by Laurie Parker
Soragni:Lab @alice.soragnilab.com · 24/07/2025
This 4th percentile funding cutoff for the NCI is so very catastrophic. Assuming a 4th percentile payline corresponds to a ~5% success rate, it would take 27 grant submissions to have an 80% chance of getting just one funded. At the current submission cap of 6 apps as PI/year that means 4.5 years
14928
Reposted by Laurie Parker
Jeremy Berg @jeremymberg.bsky.social · 22/07/2025
NIH staff are being required to fully fund ~ 50% of their grants. This means that all 4 years of an award will be paid out of this appropriation. This will help them get the appropriated funds spent, but will mean they can only fund (1/2 + 1/4*1/2) = 5/8 has many grants as they would have otherwise.
105738
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 24/07/2025
Multi-year funding at NIH: The Quickening drugmonkey.wordpress.com/2025/07/23/m...
drugmonkey.wordpress.com
Multi-year funding at NIH: The Quickening
I have apparently missed some major NIH moves that are related to my thoughts about the Multi-Year Funded Research Project Grant (RF1) mechanism. It turns out that this strategy of multi-year fundi…
2610
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 24/07/2025
"NIH has ..implemented a new policy requiring that at least one-half of the remaining funds for competing research project grants (RPGs) in FY 2025 be used to upfront fund RPG competing awards. Upfront funding provides the funding for all years of the approved project period .. from one fiscal year"
156
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 24/07/2025
Talk about your grant lotteries. Earn a 4%ile for a chance at a four year award....or bupkis. whee.
22714
Reposted by Laurie Parker
Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 19/07/2025
There is a rally on MONDAY at 4:30 PM to stand up for NIH. Please join. Many NIH employees signed the Bethesda Declaration, objecting to the destruction of NIH. The Trump NIH Director asked the signers to meet. The rally follows that meeting, in support. actionnetwork.org/ev...
27528
Laurie Parker @llparker100.bsky.social · 20/06/2025
Had such a good time at aps2025.org, so good to see everyone! A real community.
aps2025.org
APS2025 – Peptides Rising
000
Reposted by Laurie Parker
Jeremy Berg @jeremymberg.bsky.social · 23/05/2025
I started reading DrugMonkey when I was NIGMS Director. I will impressed with his command of NIH policies and practices and his clear, direct voice to scientists and to NIH. We started the NIGMS Feedback Loop blog (the first IC director-written blog) in large parts because of his example. 1/n
411926
Laurie Parker @llparker100.bsky.social · 21/05/2025
Drugmonkey is one of the people who helped me feel not alone when I was starting out. NIH funding is a tough game (even tougher now?) but it’s normal for it to feel hard!
0283
Reposted by Laurie Parker
Michael MacCoss @maccoss.bsky.social · 11/05/2025
This is the way we recommend everyone make targeted proteomics assays. We've been doing it this way for 6-7 years now but only recently got around to putting a manuscript together. We use it for everything from SRM to PRM. Great work by @deannaplubell.bsky.social
0246
Reposted by Laurie Parker
Ed Yong is offline @edyong209.bsky.social · 10/05/2025
👇🏼👇🏼👇🏼
210624
Reposted by Laurie Parker
Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 27/04/2025
The NIH firings, and the grant cuts that pushed out scientists at universities, have already had DEVASTATING effects on US science. Research labs are precious and fragile things. Taking one key person out can break it. ICYMI, we pub’d an essay on this: altnih4science.subst...
altnih4science.substack.com
It takes years to build a science lab
Productive science requires a great team, and that team develops together. That's one reason chaotic interference is dangerous for science.
310331
Reposted by Laurie Parker
anil oza @aniloza.bsky.social · 21/04/2025
UPDATE: The NIH has made this move official — publishing the draft we reported on this morning www.statnews.com/2025/04/21/t...
statnews.com
NIH bans all future grants to universities with DEI programs or Israel boycotts
NIH prohibited the awarding of new grants to institutions that have DEI programs or boycott Israeli companies
31826
Reposted by Laurie Parker
Matt Yousefzadeh @mattyousefzadeh.bsky.social · 18/04/2025
“Instead of cutting red tape, they are strangling grantees with it,”
0136
Laurie Parker @llparker100.bsky.social · 07/04/2025
This guy is doing his best
110
Laurie Parker @llparker100.bsky.social · 05/04/2025
010
Laurie Parker @llparker100.bsky.social · 05/04/2025
#HandsOff
020
Laurie Parker @llparker100.bsky.social · 05/04/2025
It was pretty crowded on the capitol lawn today!
A large crowd of people standing in front of the MN state capitol building protesting against the Trump administration. A large crowd of people standing in front of the MN state capitol building protesting against the Trump administration. A large crowd of people standing in front of the MN state capitol building protesting against the Trump administration.
010
Reposted by Laurie Parker
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 05/04/2025
“a 400-year-old institution should be making decisions with a time horizon of centuries, not news cycles. Making a principled stand now…is the single best thing Harvard could do to earn its continued place as a symbol of genuine excellence” www.bostonglobe.com/2025/04/04/o...
bostonglobe.com
Harvard’s moment of truth - The Boston Globe
The stakes are high, but the choice should not be difficult.
444597
Reposted by Laurie Parker
Leah Greenberg ❌👑 @leahgreenberg.bsky.social · 03/04/2025
I know I'm biased because it's my team but this video is very very funny
28900170
Reposted by Laurie Parker
Kate Clancy @kateclancy.bsky.social · 22/03/2025
Well I'm crying now
2141
Laurie Parker @llparker100.bsky.social · 20/03/2025
My R35 application’s Commons page now says Council meeting will be May 22nd. 🤞🏼🤷🏼‍♀️
282
Reposted by Laurie Parker
Carl T. Bergstrom @carlbergstrom.com · 19/03/2025
1. For the past thirty years I've had the best job in the world. 
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
382585927
Reposted by Laurie Parker
Derek Lowe @dereklowe.bsky.social · 19/03/2025
What it's like inside the NIH under current conditions: not good. Terrible uncertainty and low morale, and an inability to order even basic materials because of trouble with the purchasing department:
science.org
The Continuing Crisis, Part IX: Inside the NIH Now
05732
Reposted by Laurie Parker
Gina Baucom @gbaucom.bsky.social · 17/03/2025
Here's a super helpful site called Signal in the Storm that is automated to keep track of federal policy changes (EO's and Ed dept) and news re: academia. Also includes suggestions on what to do, and a faq's page about indirects, etc. Pls RT! signalinthestorm.org/index.html
signalinthestorm.org
Signal in the Storm
25440
Reposted by Laurie Parker
500 Women Scientists @500womensci.bsky.social · 15/03/2025
"Not only is silence in the face of mounting authoritarianism morally objectionable, but, as the Columbia case suggests, it’s not working" www.thecrimson.com/article/2025...
thecrimson.com
First They Came for Columbia | Opinion | The Harvard Crimson
We must learn from the past. We cannot remain silent in the face of authoritarian attacks on our peers, even if they have not yet come for us.
0195
Reposted by Laurie Parker
Drug Monkey @drugmonkey.bsky.social · 15/03/2025
www.ed.gov/about/news/p...
ed.gov
Office for Civil Rights Initiates Title VI Investigations into Institutions of Higher Education
Office for Civil Rights Initiates Title VI Investigations into Institutions of Higher Education
034
Laurie Parker @llparker100.bsky.social · 15/03/2025
@smith.senate.gov @amyklobuchar.com We need your help!
020
Reposted by Laurie Parker
Michael MacCoss @maccoss.bsky.social · 10/03/2025
2025 Quantitative Proteomics Course in Seattle WA. Space is limited, register now! This is the 11th year of offering this weeklong course. skyline.ms/project/home... #proteomicsky #massspecsky #massspec
skyline.ms
Start Page: /home/software/Skyline/events/2025 UW Course
02310
Reposted by Laurie Parker
Nature @nature.com · 07/03/2025
Academia’s often misguided view is that resilience is the ability to adapt and overcome challenges or adversity, but such an attitude can mask a toxic lab culture, say some researchers. go.nature.com/4kv5ro4
go.nature.com
‘I was told to toughen up’: is academia getting resilience all wrong?
Being repeatedly told to bounce back and develop a thicker skin can mask a toxic lab culture.
16715
Reposted by Laurie Parker
Jeremy Berg @jeremymberg.bsky.social · 07/03/2025
Hi. I am trying to understand what is going on with the changes in the NIH Clinical Center. If anyone has anything that they think might be useful, DM me or (better) find me on Signal (jeremymberg.78)
03617
Reposted by Laurie Parker
Jeremy Berg @jeremymberg.bsky.social · 07/03/2025
Hi. I am trying to understand what is going on with the changes in NIH review. If anyone has anything that they think might be useful, DM me or (better) find me on Signal (jeremymberg.78)
44917