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Marc Zimmer

@lightupscience.bsky.social
229 followers 297 following 92 posts

Author State of Science, Illuminating Disease, Bioluminescence, Cleaner Greener Planet and Glowing Genes. Life is fun when GFP glows. Chemistry professor, teaching with AI, @conncoll 🇿🇦 🇺🇸🇩🇪

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Reposted by Marc Zimmer
Simon Kuestenmacher @simongerman600.bsky.social · 11/09/2026
This lovely animated map shows the lighthouses of New England. The dark theme instantly makes you feel how important the sight of a lighthouse would've been for mariners throughout history. Source: mapped.earth buff.ly/cfUevAQ HT @AaronJBecker
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Claire G. Griffin @polargriffin.bsky.social · 25/08/2026
Oof. This is less than when I was a GRFP 15 years ago
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Reposted by Marc Zimmer
Leo Hickman @leohickman.carbonbrief.org · 24/08/2026
The daily global average sea surface temperature has just reached its highest level on record, per C3S. "The timing of the record is particularly notable. Global ocean temperatures are typically highest in March and April, following the austral summer, yet this record has been reached in August."
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Simon Kuestenmacher @simongerman600.bsky.social · 23/08/2026
The highest mountain in the world is Mt Everest, right?! Well, if you count the actual mountain rather than from sea level Mauna Kea is the highest. If look for the point that's furthest away from the earth's center it's Chimborazo. Source: buff.ly/2zZ1lPt
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Simon Kuestenmacher @simongerman600.bsky.social · 14/08/2026
Political Studies is the most gender equal subject. This fun grap by @telegraph shows A-level gender disparity in 2026.
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Reposted by Marc Zimmer
bioRxivpreprint @biorxivpreprint.bsky.social · 03/08/2026
Discovery of a buried charge-network GFP-fold family spanning prokaryotes and eukaryotes (Draft manuscript) www.biorxiv.org/content/10.64898/20…
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 03/08/2026
Discovery of a buried charge-network GFP-fold family spanning prokaryotes and eukaryotes (Draft manuscript) www.biorxiv.org/content/10.64898/20…
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Robert E. Campbell @campbell-lab.bsky.social · 17/07/2026
The hardest puzzle ever? It's got to be a protein! My hobby is turning protein structures into #OddlySatisfying 3D puzzles. Here's GFP (PDB: 1EMA)! 🧩🧬🧪 🎥 youtube.com/shorts/3ljlR... 📸 www.instagram.com/reel/Da2NKpT...
youtube.com
The hardest puzzle ever? It’s a protein!
YouTube video by Proteotopical
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Reposted by Marc Zimmer
Stateside Scouser @spokanescouser.bsky.social · 19/01/2025
Did he miss chances during that stretch? Yes. Did he become Harry Kane? No. But great chemistry with #11, and always a threat to affect the game. People act like he’s cooked and needs to go to Saudi, but the reality is he’s a 25yo player that needs to mature but can have great stretches of form.
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Reposted by Marc Zimmer
Zebrafish Rock! @zebrafishrock.bsky.social · 21/06/2026
Full spectrum of multi-colored "zebrabow" larvae. Credit to @jhenninger.bsky.social. #PrideMonth 🏳️‍🌈🐟 #ZebrafishZunday 🧪
Fluorescent brainbow-based "zebrabow" larvae neatly aligned by color. Each larva expresses up to three fluorescent proteins (RFP, CFP, YFP) at varying levels giving a unique color.
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Marc Zimmer @lightupscience.bsky.social · 12/05/2026
My new piece in @us.theconversation.com : Genome sequencing can connect ancient plague graves to the Black Death and trace a COVID-19 outbreak from one conference room across a continent. But DNA alone is not enough. Disease history needs human context too.
theconversation.com
Genome sequencing is rewriting the history of disease outbreaks – but without social context, it can tell only part of the story
From the Black Death to the COVID-19 pandemic, combining the genetic data of a pathogen with historical records, archaeological artifacts and epidemiological studies can uncover its origins.
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Marc Zimmer @lightupscience.bsky.social · 06/05/2026
Bioluminescent algae’s blue light harnessed to make 3D-printed shapes www.theguardian.com/science/2026...
theguardian.com
Bioluminescent algae’s blue light harnessed to make 3D-printed shapes
Scientists suggest algae could be embedded within biosensors that glow when toxins detected in the environment
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Marc Zimmer @lightupscience.bsky.social · 01/05/2026
Mindboggling Science article #2. AI can now match or exceed physician-level clinical diagnostic reasoning.
science.org
AI can reason like a physician—what comes next?
Text-based AI can think like a physician; the challenge is achieving safe clinical implementation
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Marc Zimmer @lightupscience.bsky.social · 26/04/2026
uni-koeln.de
Calcium sensor improves imaging of nerve cells
The new sensor is based on a special fluorescent protein from which it was not previously possible to develop a biosensor
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Reposted by Marc Zimmer
Simon Kuestenmacher @simongerman600.bsky.social · 25/04/2026
This chart might look political, but it’s really about data science. The UK can rank great or poorly depending on the KPIs you choose. Our choice of data decides how we view reality.
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Ryan Fink @finkryan.bsky.social · 24/04/2026
PinkyCaMP is finally published!! My first paper co-first authored with @sikmys.bsky.social where we make a great optogenetic and multiplex compatible red calcium indicator. Thank you to @massecklab.bsky.social and @campbell-lab.bsky.social for guiding this journey www.nature.com/articles/s41...
nature.com
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities - Nature Methods
PinkyCaMP is a red genetically encoded calcium indicator with improved brightness and photostability. Derived from mScarlet, it does not exhibit photoswitching upon blue light illumination and is ther...
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Marc Zimmer @lightupscience.bsky.social · 24/04/2026
nature.com
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities - Nature Methods
PinkyCaMP is a red genetically encoded calcium indicator with improved brightness and photostability. Derived from mScarlet, it does not exhibit photoswitching upon blue light illumination and is ther...
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Reposted by Marc Zimmer
Andy Muirhead @andymuirhd.bsky.social · 12/04/2026
In France, legislation came into effect recently for all car parks that have over 80 spaces to be covered with solar panels. Estimated to add around 11GW of renewable energy capacity to the national grid. Why not do likewise in Scotland? Braehead, Silverburn, Glasgow Fort etc.
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c0nc0rdance @c0nc0rdance.bsky.social · 09/04/2026
I'm deep down the rabbit hole on FROGFISH, 60 species of anglerfish in family Antennariidae. They are deeply, utterly WEIRD & MARVELOUS. Most walk on modified fins. Others use jet propulsion. Some are capable of air-breathing. Some are "hairy", others blend perfectly in sargassum.
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Marc Zimmer @lightupscience.bsky.social · 08/04/2026
"Kleptoproteinism" - I have learned a new word today, and I love it.
discovermagazine.com
This Glowing Fish Steals Bioluminescence Instead of Making Its Own Light
Learn more about the golden sweeper, a type of fish that steals bioluminescent proteins from its prey to glow, a rare case of kleptoproteinism.
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Reposted by Marc Zimmer
Chris Mah @echinoblog.bsky.social · 01/07/2025
Leipidonotus squamatus- stunning scaleworm shot by Alexander Semenov! #worldpolychaeteday!
green worm with overlapping scales
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Alex Maile @anoplogaster.bsky.social · 08/04/2026
‼️NEW ANGLERFISH PAPER! 🐟🎣 So excited to share the final part of my Master’s research! We explore the bizarre tacklebox of anglerfish lures and show how these fishes evolved different ways to attract prey and maybe even mates in the deep sea. 🧪🦑🌊🦇🦀 Open access paper link: doi.org/10.1643/i202...
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Marc Zimmer @lightupscience.bsky.social · 08/04/2026
My new young adult book, Diseases Without Borders, is officially out. It explores plagues, pandemics, and the science that helps us understand how disease moves through our interconnected world. #YoungAdultBooks #Pandemics #ScienceBooks @lernerbooks.bsky.social #21stCenturyBooks
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Marc Zimmer @lightupscience.bsky.social · 08/04/2026
theprint.in/feature/chin...
theprint.in
Chinese scientists develop glow-in-the-dark plants. Avatar world now possible
Led by Dr Li Renhan, founder of Magicpen Bio, more than 20 species, including orchids, sunflowers and chrysanthemums, have already been engineered to shine at night.
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Marc Zimmer @lightupscience.bsky.social · 07/04/2026
theprint.in/feature/chin...
theprint.in
Chinese scientists develop glow-in-the-dark plants. Avatar world now possible
Led by Dr Li Renhan, founder of Magicpen Bio, more than 20 species, including orchids, sunflowers and chrysanthemums, have already been engineered to shine at night.
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Reposted by Marc Zimmer
Ethan Mollick @emollick.bsky.social · 31/03/2026
My prediction for the latest trend in academic buildings: Faraday cage testing halls (including bathrooms) with no signal for assessment.
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Marc Zimmer @lightupscience.bsky.social · 01/04/2026
Ultraviolet light illuminates species-specific biofluorescent (🙄)casque patterns in cassowaries www.nature.com/articles/s41...
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Marc Zimmer @lightupscience.bsky.social · 25/03/2026
nature.com
Major conference catches illicit AI use — and rejects hundreds of papers
The papers’ watermarks allowed organizers to detect use of large language models in peer review.
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Reposted by Marc Zimmer
Simon Kuestenmacher @simongerman600.bsky.social · 19/03/2026
Look at the size of Vietnam in green. Then look at Iran in blue. The US only had troops in half of Vietnam and peak strength was 580K. The idea of fighting a ground war in Iran as Trump is suggesting sounds rather adventurous to me. Great use of a size comparison map by @NavyStrang btw!
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Simon Kuestenmacher @simongerman600.bsky.social · 07/03/2026
The UK used less coal in 2025 than they did in 1600, when Shakespeare was writing Hamlet. Source: buff.ly/Ifmz1Eo
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Reposted by Marc Zimmer
Simon Kuestenmacher @simongerman600.bsky.social · 01/03/2026
This map by @xruiztru shows how the world reacted to the US-Israeli strikes on Iran. The Iranian diaspora appears to be in favour of the strikes.
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Reposted by Marc Zimmer
Eric Topol @erictopol.bsky.social · 01/03/2026
That's right. Worse than Pointless www.nytimes.com/2026/02/23/o...
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Marc Zimmer @lightupscience.bsky.social · 27/02/2026
The greatest risk of AI in higher education isn’t cheating – it’s the erosion of learning itself. Lots of good ideas in this article.
theconversation.com
The greatest risk of AI in higher education isn’t cheating – it’s the erosion of learning itself
Automating knowledge production and teaching weakens the ecosystem of students and scholars that sustains universities, raising existential questions about their mission.
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Marc Zimmer @lightupscience.bsky.social · 25/02/2026
xenospectrum.com
すべてを統べる1つのタンパク質:クラゲを緑色に光らせるタンパク質をモデルに据えることが、生物学の効率化にどう役立つか | XenoSpectrum
ショウジョウバエ、マウス、ゼブラフィッシュ、酵母、そして小さな線虫C. elegansは、現代生物学を支えてきたモデル生物である。
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Marc Zimmer @lightupscience.bsky.social · 24/02/2026
New piece out today: what if biology crowned a model protein the way it has model organisms? My pick: GFP (the jellyfish glow protein) — a shared standard could streamline a lot of biology. doi.org/10.64628/AAI... #biology
doi.org
1 protein to rule them all – why crowning the protein that makes jellyfish glow green as a model can help scientists streamline biology
Researchers have been studying tens of thousands of proteins and even more variations without a yardstick to compare their results.
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Reposted by Marc Zimmer
Ethan Mollick @emollick.bsky.social · 14/02/2026
The transition from “AI can’t do novel science” to “of course AI does novel science” will be like every other similar AI transition. First the over-enthusiastic claims that are debunked, then smart people use AI to help them, then AI starts to do more of the work, then minor discoveries, & then…
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Marc Zimmer @lightupscience.bsky.social · 14/02/2026
A stack of books just showed up at my door, which feels like science + magic + cardboard. Diseases Without Borders out April 7.
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terence @tterence.bsky.social · 07/02/2026
The Congo basin. #rayshader adventures, an #rstats tale
A visualisation of the rivers of the Congo basin
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Simon Kuestenmacher @simongerman600.bsky.social · 07/02/2026
Feels far fetched right now?
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Marc Zimmer @lightupscience.bsky.social · 05/02/2026
‘Living biosensor’ lights up to detect wine spoilage in real time. I want a lit-up wine photo!!! Luciferase + Acetic acid www.chemistryworld.com/news/living-...
chemistryworld.com
‘Living biosensor’ lights up to detect wine spoilage in real time
Genetically modified bacteria glow in high levels of acetic acid, a common signal that wine has gone bad
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David Ho @davidho.bsky.social · 20/01/2026
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again. www.nature.com/immersive/d4...
This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.
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Marc Zimmer @lightupscience.bsky.social · 19/01/2026
Starred Kirkus review today for my upcoming book DISEASES WITHOUT BORDERS @lernerbooks.bsky.social (out Apr 7, 2026). Kirkus calls it: “An exceptionally clear and inspiring resource combining a human-centered narrative with compelling science.” www.kirkusreviews.com/book-reviews...
kirkusreviews.com
DISEASES WITHOUT BORDERS | Kirkus Reviews
A biological and historical primer on plagues.
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Rita Strack @ritastrack.bsky.social · 18/01/2026
What can "model proteins" do for biochemistry? Check out this press release and read the original Comment! phys.org/news/2026-01... @lightupscience.bsky.social
phys.org
Chemist proposes shared 'model proteins' to improve reproducibility in protein science
Protein scientists could improve reproducibility and coordination across the field by rallying around a small, shared set of "model proteins," according to a new Perspective by Connecticut College che...
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Marc Zimmer @lightupscience.bsky.social · 16/01/2026
Model organisms → model protein: a shared reference protein system to support reproducible protein research. Phys.org just covered a perspective I wrote for Protein Engineering, Design & Selection
phys.org
Chemist proposes shared 'model proteins' to improve reproducibility in protein science
Protein scientists could improve reproducibility and coordination across the field by rallying around a small, shared set of "model proteins," according to a new Perspective by Connecticut College che...
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Marc Zimmer @lightupscience.bsky.social · 08/01/2026
I just published an op-ed in U.S. News about how college teaching is changing with AI tools like ChatGPT, and what we should do next. Curious how others are handling this in real classrooms. #HigherEd #AI #Teaching
usnews.com
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Simon Kuestenmacher @simongerman600.bsky.social · 29/12/2025
Here are some European train journeys for your bucket list!
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Philip Ball @philipcball.bsky.social · 27/12/2025
Funny thing though: Musk and the other tech lords are still saying such things, and the media credulity has not lessened one whit. And they are richer than ever.
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FocalPlane @focalplane.bsky.social · 19/12/2025
We’ve highlighted some wonderful images and researchers in our ‘Featured image’ series in 2025. To celebrate, we’re inviting you to vote for your favourite in our image competition! #FluorescenceFriday Check them out here: focalplane.biologists.com/2025/12/19/v...
focalplane.biologists.com
Vote for your favourite 'Featured image' from 2025 - FocalPlane
Vote for your favourite 'Featured image' from 2025 - News
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Marc Zimmer @lightupscience.bsky.social · 08/12/2025
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royalsociety.org
Finalists 2025 | Royal Society
2025 finalists for the Royal Society Publishing Photography Competition.
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