Reposted by Kristen Naegle (she/her)Chrystal Starbird @drstarbird.bsky.social · 01/10/2026And… I am SO excited to share the first research preprint from my group! In this paper we determined several cryoEM structures to visualize the entire cell-to-cell bridging complex formed by TAM receptor and ligand, bringing into 3D a common graphical depiction. www.biorxiv.org/content/10.6... 78420
Reposted by Kristen Naegle (she/her)Ketan Joshi @ketanjoshi.co · 09/09/2026"Oh, you're criticising data centres? But you USED A DATA CENTRE to publish your post??? Hypocritical much????" Time to put this fossil fuel PR inspired talking point to bed forever. Why the 'Mr Gotcha' gambit is wrong in two very important ways: 15486222
Reposted by Kristen Naegle (she/her)Jess McLaughlin, PhD (they/them) @jfmclaughlin92.bsky.social · 24/07/2026"Hey Jess, why do you spend so much of the classroom time of your genetics course talking about ethics?" 616149
Reposted by Kristen Naegle (she/her)Sholto David @sholtodavid.bsky.social · 21/07/2026Today I'm posting a blog about another ridiculous antibody blunder. Dozens of papers in the senescence and ageing field have mistakenly used an antibody for E. coli β-galactosidase when trying to stain for the human protein with the same name. forbetterscience.com/2026/07/21/d... 49146
Reposted by Kristen Naegle (she/her)Jeff Lewis @lewislab.bsky.social · 20/07/2026Nice write-up of our latest paper: news.uark.edu/articles/82610 And could not have been done without the support of NSF and NIH.news.uark.eduNew Study Finds Heat Shock Can Drive Changes in Protein ModificationsResearch provides insight into how yeast cells respond to stressful conditions with implications for larger organisms that share the same proteins. 0169
Reposted by Kristen Naegle (she/her)Mark Peifer (He, him) @peiferlabunc.bsky.social · 07/07/2026One more week to submit comments on the proposed changes to Federal funding that would ditch peer review and other quality controls and let political appointees decide how to spend the taxpayer's dollars. Please look in the link with instructions 🧪 044
Reposted by Kristen Naegle (she/her)Drug Monkey @drugmonkey.bsky.social · 28/06/2026“The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. “ 0256
Reposted by Kristen Naegle (she/her)Drug Monkey @drugmonkey.bsky.social · 28/06/2026“Ranking all life science preprints on a single scale simultaneously, across neuroscience, structural biology, bioinformatics, and plant biology, assumes a commensurability that does not exist.” 1298
Reposted by Kristen Naegle (she/her)johnedwinmason @johnedwinmason.bsky.social · 17/06/2026Very happy to see this new addition to our cityscape — a free little food pantry.* It's outside First Baptist Church on West Main. Charlottesville friends, please help me fill it up for our many neighbors who are in need. 28024
Reposted by Kristen Naegle (she/her)Anna Dearman @annadearman.bsky.social · 11/06/2026www.nature.com/articles/s41... Such an excellent explanationnature.comPolygenic risk scores are not genetic predispositions - Nature Human BehaviourNature Human Behaviour - Polygenic risk scores are not genetic predispositions 0105
Reposted by Kristen Naegle (she/her)Livable Cville @livablecville.bsky.social · 07/06/2026People shouldn’t have to die in order to convince their city that better bike/ped/ADA infrastructure is necessary. But unfortunately that’s often what it takes. 1173
Reposted by Kristen Naegle (she/her)Reese Richardson @reeserichardson.bsky.social · 28/05/2026Here's the repository where we're collecting everything that we've found: doi.org/10.5281/zeno...doi.orgProblematic images in vendor antibody verification dataThis repository hosts documentation of suspicious, apparently manipulated or otherwise problematic antibody verification data in the catalogs of laboratory reagent vendors. As of 28 May 2026, we have ... 1323
Kristen Naegle (she/her) @knaegle.bsky.social · 05/06/2026I have another Abcam antibody to add to your list. We tried multiple times and could never see signal on Abcam PD1 pY463 and now I know why! Image contrast from their catalog shows deep manipulation. Our data is here (final figure) - easy method for pY ab validation www.biorxiv.org/content/10.1... 031
Reposted by Kristen Naegle (she/her)Erin Fogg says Free Link @criminalerin.bsky.social · 20/05/2026Every time we hear about how genAI has pushed another teenager to suicide, another person into committing a mass shooting, or generated CSAM of school girls used to blackmail their schools, remember we were told that what we'd be hearing about is a cure to every cancer, and global poverty itself 121720658
Reposted by Kristen Naegle (she/her)uvaresearch.bsky.social @uvaresearch.bsky.social · 01/05/2026New UVA School of Medicine research streamlines drug discovery for inherited diseases. Led by Xiaowei Hu and Ani Manichaikul, the tool is 24% more accurate and uses diverse data to ensure treatments benefit all ancestries ow.ly/6K6J50YRYQC 001
Reposted by Kristen Naegle (she/her)Mariko Bennett @nachoriko.bsky.social · 24/03/2026I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity. 491706568
Reposted by Kristen Naegle (she/her)🎃 Killy Witches 👻 @tillybridges.bsky.social · 24/03/2026it’s not hyperbole, JKR literally said support for HP is support for her transphobia and she uses the money she makes from it to TRY TO TAKE OUR RIGHTS AWAY if you watch that show please don’t ever speak to me again trans lives are more important than your fandom of a terrible human’s IP 101048554
Reposted by Kristen Naegle (she/her)American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 24/03/2026As a child, @phosphotig.bsky.social dreamed of being an astronaut, but her curiosity led her to scientific research. Now, she leads her own lab at UNC-Chapel Hill, & studies oxidative stress to find better therapies for triple-negative breast cancer. #WomensHistoryMonth www.asbmb.org/asbmb-today/...asbmb.orgLearning, leading and lifting othersTigist Tamir’s journey from aspiring astronaut in Ethiopia to cancer researcher at the University of North Carolina highlights the power of mentorship, persistence and curiosity in shaping a scientifi... 13018
Kristen Naegle (she/her) @knaegle.bsky.social · 20/03/2026Project Hail Mary was just as good as I hoped it would be. However, content warning for biologists -- at one point there is an unbalanced centrifuge. I just closed my eyes until it was over. 161
Kristen Naegle (she/her) @knaegle.bsky.social · 28/01/2026The NIH moving to only allowing 6 total applications per year will have a disproportionate effect on marginalized scientists. 021
Reposted by Kristen Naegle (she/her)Timo B. Roettger @timoroettger.bsky.social · 28/01/2026"P-Hacking with one prompt" by Shigeto Kawahara. TL/DR: Ask LLMs to find a significant effect, and they will oblige. www.researchgate.net/publication/...researchgate.net(PDF) P-hacking with one promptPDF | This brief note reports a mini-experiment, which tested whether major AI systems (Gemini, Claude, and ChatGPT) readily perform p-hacking when... | Find, read and cite all the research you need o... 12816
Reposted by Kristen Naegle (she/her)Erin Reed @erininthemorning.com · 06/01/20261. Did you know that Girl Scouts has, for a long time, accepted trans girls and nonbinary scouts? Trans kids are under attack. Every year, I make a thread of trans and nonbinary girl scouts you can get your cookies from. Lets get our cookies from them this year in solidarity!erininthemorning.com2026 Trans Girl Scouts To Order Cookies From!This year, consider ordering your Girl Scout cookies from a trans girl scout to make their day! 9286004465
Reposted by Kristen Naegle (she/her)Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 05/01/2026Once again, I implore media outlets to stop saying these are CDC decisions. These are changes being made unilaterally by RFK Jr. against the expert advice of CDC scientists. I note that RFK Jr. no longer recommends flu vaccine for kids in the midst of a horrible influenza year.nbcnews.comCDC overhauls childhood vaccine schedule to resemble Denmark in unprecedented moveThe new U.S. guidelines recommend all children get vaccines for 11 diseases, compared with the 18 previously on the schedule. 631350609
Reposted by Kristen Naegle (she/her)Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 21/11/2025Wow 1156
Reposted by Kristen Naegle (she/her)Leah Teague 🏳️⚧️ @leah.teague.bio · 19/11/2025I agree with EVERY SINGLE ONE of these rules. I came to most of them on my own because I never had any mentorship for my mentorship. And despite being published in PLOS Comp Bio, they apply to EVERY undergraduate and masters student project. 0104
Reposted by Kristen Naegle (she/her)BK. Titanji @boghuma.bsky.social · 23/10/2025Marching and protesting is great but real action is even better. If you can afford it, find and donate to a local food pantry in your area. The families that depend on SNAP benefits could really use the support over coming weeks to months.❤️🫂 give.feedingamerica.org/SnP--N8F9EuA...give.feedingamerica.orgJoin me in ending hungerI just donated to @FeedingAmerica to help make sure families and kids have the meals they need! http://feeding.am/givemeals 45720
Reposted by Kristen Naegle (she/her)Solomon @solomonrmissouri.com · 12/08/2025Hey guys... this is serious please go and opt out NOW! 22258172
Reposted by Kristen Naegle (she/her)Denis Wirtz @deniswirtz.bsky.social · 11/08/2025These are the most challenging times for early-career scientists and engineers. My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers. We found 437 of them. Download it freely here: research.jhu.edu/rdt/funding-... 6313201
Kristen Naegle (she/her) @knaegle.bsky.social · 31/07/2025Please give feedback. I know I'm considering the new NIH mandate that open access has to be immediately available, meaning that grantees are footing open access bills at journals to meet the mandate. That can mean $5-$12K a paper of taxpayers money. 000
Kristen Naegle (she/her) @knaegle.bsky.social · 14/07/2025No, no, this is all wrong. The quote is actually supposed to be "let them eat cake". Apropos of nothing, Happy Bastille day to all those who celebrate. 020
Reposted by Kristen Naegle (she/her)Chise @sailorrooscout.bsky.social · 12/07/2025There are currently more kids in Texas with measles than there are transgender collegiate athletes in all of America. Guess which one they want you to focus on. 3865862343
Kristen Naegle (she/her) @knaegle.bsky.social · 02/07/2025$123,536,510 of federally appropriated funding has been stolen from Virginia schools 010
Reposted by Kristen Naegle (she/her)Siva @sivav.bsky.social · 28/06/2025On just one Friday the Supreme Court brought my citizenship into question and the Trump administration gutted my employer and possibly threaten my career. I could only write about one of those things. newrepublic.com/article/1973...newrepublic.comUVA President James Ryan Caved to MAGA—and They Forced Him Out AnywayRyan had not fought Trump on DEI and other matters. His forced ouster proves that no capitulation is enough. 47832
Reposted by Kristen Naegle (she/her)W. Carson Byrd @wcbyrdphd.bsky.social · 28/06/2025In the fallout of James Ryan resigning from UVA, @sivav.bsky.social provides a clear argument of what higher ed is facing & why capitulation will not save you. newrepublic.com/article/1973... 29141
Reposted by Kristen Naegle (she/her)jenntheflower @jenntheflower.bsky.social · 28/06/2025thank you, @sivav.bsky.social, for putting a lot of what I’m furious about in plain language. newrepublic.com/article/1973...newrepublic.comUVA President James Ryan Caved to MAGA—and They Forced Him Out AnywayRyan had not fought Trump on DEI and other matters. His forced ouster proves that no capitulation is enough. 0129
Reposted by Kristen Naegle (she/her)Chise @sailorrooscout.bsky.social · 25/06/2025PLEASE SHARE 🧪‼️ Vaccination schedules on the CDC website have already started changing under RFK Jr. Scientific American has published a guide to the EVIDENCE-BASED vaccine recommendations in place BEFORE ACIP members were removed by the administration. www.scientificamerican.com/article/see-...scientificamerican.comHere’s Your Cheat Sheet for Vaccine Recommendations Backed by ScienceThese graphics will guide you through science-based vaccine guidelines for children and adults 4230512166
Kristen Naegle (she/her) @knaegle.bsky.social · 25/06/2025So happy to see this work is out and I hope it helps people find their best lab fit! 051
Reposted by Kristen Naegle (she/her)Livable Cville @livablecville.bsky.social · 21/06/2025Charlottesville is turning into an e-bike city! Great article from @nathanalderman.bsky.social on the @cvillecityhall.bsky.social e-bike voucher program, which is one piece of the city’s efforts to create a better transportation system. c-ville.com/citys-e-bike...c-ville.comCity’s e-bike voucher program provides some extra pedal power - C-VILLE WeeklyUVA doctoral candidate T.C.A. Achintya needed a better way to get around. A new program from the City of Charlottesville made it happen. “I had contemplated buying a regular bike, since I don’t own a ... 0235
Reposted by Kristen Naegle (she/her)BWJones @bwjones.bsky.social · 08/06/2025Almost all Nobel Prizes are awarded for work that is exploratory, or absolutely basic science with no obvious commercial or medical benefit. You cannot predict where advancements come from, so you have to invest in science and scientists. Targeted (corporate) science investment will never do this. 4289118
Reposted by Kristen Naegle (she/her)Scott Delaney @scott-delaney.bsky.social · 19/05/2025Grant freezes versus terminations feel different, but they have the same practical effect. We should start treating freezes as terminations, both of which can be undone by HHS / NIH whenever they want—or by court order if they refuse. They’re all illegal. 214152
Reposted by Kristen Naegle (she/her)Anna Kornbluh @annakornbluh.bsky.social · 18/05/2025say it again: 4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x demolishing higher education is economic sabotage 6547951843
Kristen Naegle (she/her) @knaegle.bsky.social · 14/05/2025This is devastating for American science, health, technology, and the economy. 030
Reposted by Kristen Naegle (she/her)Noam Ross @noamross.net · 13/05/2025We updated the reporting form today to clarify that we're also collecting info on "stop-work orders, unexpected non-renewals, or effective termination through updated notice of award." grant-watch.us/submit-nih.h... 087
Reposted by Kristen Naegle (she/her)Santiago Mayer @santiagomayer.com · 11/05/2025We’ve become so desensitized to corruption that the Attorney General who spent years lobbying on behalf of Qatar approved a private jet gift from Qatar and it’s not even in the top 10 scandals of the week. 289138004003
Reposted by Kristen Naegle (she/her)Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 10/05/2025“The results revealed that researchers who received renewals without a funding gap were less likely to switch research topics and investigate a wide array of subjects than were those in the control group, and they produced papers featuring newer or more unconventional combinations of ideas” 14225
Kristen Naegle (she/her) @knaegle.bsky.social · 08/05/2025I heard the new pope is a math major. So that means he understands both sin and sin^-1 right? 150
Kristen Naegle (she/her) @knaegle.bsky.social · 30/04/2025It has been scientifically shown that all dogs can engage an anchor mode by which their effective weight is quadruple their normal weight. 020
Kristen Naegle (she/her) @knaegle.bsky.social · 26/04/2025For Charlottesville peeps, MAGA-endorsing businesses include Charlottesville Tire and Auto, First Free Coffee, The Gym, Start 2 Finish nutrition, and several contractors and photographers. 000
Reposted by Kristen Naegle (she/her)Jen Bendery @jbendery.bsky.social · 26/04/2025NEW: PublicSquare, a website that lets you search for businesses in your community that explicitly want you to know they endorse Trump/MAGA values, is backfiring as people use it to boycott those businesses. www.huffpost.com/entry/public...huffpost.comWebsite For MAGA-Friendly Businesses Backfires As People Use It For BoycottsSocial media posts about PublicSquare have gone viral as Trump critics use it to find companies not to support – the opposite of what the site was set up for. 480110043657
Reposted by Kristen Naegle (she/her)Alexios Mantzarlis @mantzarlis.com · 21/04/2025Update: I have been able to confirm grants worth ~$6M were terminated but think the total may be as high as $94M. If you or your colleagues got a termination letter, considering responding to the form. You can do so anonymously. 15431