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Michelle Kho, PT, PhD

@khome1.bsky.social
147 followers 90 following 4 posts

Professor, School of Rehabilitation Science, McMaster University | ICU Physiotherapist | Clinical Triallist

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Reposted by Michelle Kho, PT, PhD
Segun Olusanya (He/Him) @drfreeze.bsky.social · 10/12/2025
Go Arthur!
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 10/12/2025
Chief Investigator Angelique de Man and Senior Investigator Sander Rozemeijer share the results from the #VITaCCA trial and what it means for clinicians after presenting at #CCRdownunder Livestream -> www.criticalcarereviews.com @jama.com
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 09/12/2025
Co-Chief Investigators Brenda O'Neill and Danny McAuley share the results of the #iRehab trial after presenting at #CCRdownunder Livestream -> www.criticalcarereviews.com @jama.com
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Reposted by Michelle Kho, PT, PhD
Goodishintent @omnintensivist.bsky.social · 10/12/2025
Wow wow wow Beautiful trial. Nice editorial. Worth watching if you intubate patients.
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Reposted by Michelle Kho, PT, PhD
NEJM.org @nejm.org · 10/12/2025
In a randomized trial involving critically ill patients undergoing intubation in EDs or ICUs, the use of ketamine for the induction of anesthesia did not lead to significantly lower in-hospital mortality than etomidate. Full trial results: nej.md/44EOlxB @criticalcarereviews.com
CCR Down Under 2025 
Original Article | Dec. 9, 2025 | NEJM.org 
Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults 

Figure 1. In-Hospital Death, According to Trial Group. 

The NEJM identity sits at the bottom.
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 04/09/2025
Review of Current Management of Myocardial Infarction CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 21/08/2025
Noninvasive respiratory supports in ICU CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
NIDUS Delirium Network @nidus-delirium.bsky.social · 15/08/2025
Learn about non-pharma #delirium management 14th Johns Hopkins #ICURehab Conference with Dr Dale Needham & Multi-D Team (RN, PT, OT, SLP) In-Person at Johns Hopkins Nov 6-7, 2025 Supported by @nidus-delirium.bsky.social! Register: www.ICURehabNetwork.org @icurehab.bsky.social
Flyer for the 14th Johns Hopkins ICU Rehab Conference with Dr Dale Needham.
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Reposted by Michelle Kho, PT, PhD
Chris Carroll, MD @chriscarrollmd.com · 16/08/2025
@thanhneville.medsky.social! So excited for your talk at #CHEST2025 on Humanizing Dying in the ICU and the @3wishesprogram.bsky.social!
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Reposted by Michelle Kho, PT, PhD
KaminskiMed @kaminskimed.bsky.social · 16/08/2025
Congratulations @thanhneville.medsky.social for being elected to give the Richard Irwin honor lecture @ #CHEST2025 titled "Humanizing Dying in the ICU, One Wish at a Time: The 3 Wishes Program". 👏🏼@accpchest.bsky.social👏🏼 She also deserves an award for #DoctorsWhoCook #PeopleIlookUpTo
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Reposted by Michelle Kho, PT, PhD
Alison Hoens @physioktbroker.bsky.social · 04/08/2025
Important tool to facilitate accurate and complete reporting of evaluation of AI models for health advice 🧪
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Reposted by Michelle Kho, PT, PhD
kinesinmotors.bsky.social @kinesinmotors.bsky.social · 02/08/2025
🍂 💸 🧪 UCLA Federal Grant Freeze by the Administration
laist.com
UCLA tells researchers to 'immediately stop spending' after Trump administration freezes grant funds
The Trump administration cited alleged antisemitism at UCLA as a reason for suspending the funding. Years worth of research could be lost, one UCLA researcher said.
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Reposted by Michelle Kho, PT, PhD
Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 31/07/2025
Wish 1: To get relief from dyspnea (achieved w/ narcotics) Wish 2: To go outside (we brought many tanks bc his high O2 needs) Wish 3: To eat good gluten-free pizza (ordered & donated by me). Before he died, he said it was the best 48hrs he's had in a long time. I cried. @3wishesprogram.bsky.social
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Reposted by Michelle Kho, PT, PhD
Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 31/07/2025
We are now at 1976 followers! If not already, please consider giving our @3wishesprogram.bsky.social a follow! I'm on a mission to spread it far and wide!
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Reposted by Michelle Kho, PT, PhD
3 Wishes Program @3wishesprogram.bsky.social · 31/07/2025
We are now at 1992 followers!!! Hoping to hit 2000!
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Reposted by Michelle Kho, PT, PhD
JAMA @jama.com · 26/07/2025
Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting. ja.ma/46ljurR
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 25/07/2025
The application of therapeutic plasma exchange in sepsis and septic shock: A narrative review CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 25/07/2025
Ethical Considerations for Patients Requiring Extracorporeal Cardiopulmonary Resuscitation CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 23/07/2025
Does ability and willingness to use continuous RRT improve patient outcomes? A few answers, plenty of questions and opportunities for research CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 20/07/2025
The first trial for CCR Down Under 2025 is RSI from the Pragmatic Critical Care Research Group ➡️Ketamine vs etomidate for emergency tracheal intubation ➡️n= 2364 Join us in Melbourne - Dec 9 & 10 criticalcarereviews.com/meetings/ccr... CCR Down Under is run with the Alfred ICU & Monash Uni
criticalcarereviews.com
CCR Down Under 2025
Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 14/07/2025
Crosstalk between lung and extrapulmonary organs in sepsis-related acute lung injury/acute respiratory distress syndrome CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…
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Reposted by Michelle Kho, PT, PhD
Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 09/07/2025
My research coordinator told me she cried when she heard my grant on @3wishesprogram.bsky.social in safety net hospitals got renewed. She told me even tho I have other projects, this was main reason she wanted to work for me--to bring #3WP to the underserved. I love the people I work with.
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 10/07/2025
Today's Paper of the Day is: Opioid Tolerance in Critical Illness criticalcarereviews.com/latest-evid… Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
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Reposted by Michelle Kho, PT, PhD
Bharath Kumar @bharathkumartv.bsky.social · 10/07/2025
Very interesting- please also see our work from India recently published in CCM: pubmed.ncbi.nlm.nih.gov/40521972/
pubmed.ncbi.nlm.nih.gov
Persistent Critical Illness Among Intensive Care Patients in India: A Registry-Embedded Cohort Study - PubMed
In this cohort of critically ill patients in India, as ICU stay increased, the prognostic performance of acute illness characteristics decreased whereas that of antecedent characteristics remained poo...
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Reposted by Michelle Kho, PT, PhD
Alison Hoens @physioktbroker.bsky.social · 10/07/2025
Identifying and addressing patients’ expectations 🧪 jamanetwork.com/journals/jam...
jamanetwork.com
Improving Patients’ Treatment Expectations
This JAMA Insights offers evidence-based communication strategies for addressing patient treatment expectations, which can improve outcomes and reduce adverse effects.
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Reposted by Michelle Kho, PT, PhD
NEJM.org @nejm.org · 09/07/2025
In this 60-Second Journal Club, NEJM Editorial Fellow Abarna Pearl, MD, MPH, summarizes the BALANCE trial comparing antibiotic treatment for 7 versus 14 days in patients with bloodstream infections. Read the full article and accompanying Research Summary: nej.md/3Z5bTJD #MedSky #IDSky
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Reposted by Michelle Kho, PT, PhD
Kerry Hood @kerryhood.bsky.social · 04/07/2025
Nice to see this paper published - really important topic to think about how we manage people who want to withdraw from a trial and the principles that are important in operationalising this. @ukcrc-ctu.org.uk journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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Reposted by Michelle Kho, PT, PhD
Jack Iwashyna @iwashyna.bsky.social · 03/07/2025
#ICUreadings Contemporary: Frailty dynamics in the ICU: link.springer.com/article/10.1... Classic: Wes Ely did an RCT on SBTs while Chief Resident: www.nejm.org/doi/full/10....
link.springer.com
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study - Intensive Care Medicine
Purpose Frailty is common in critically ill patients but the timing and optimal method of frailty ascertainment, trajectory and relationship with care processes remain uncertain. We sought to elucidat...
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Reposted by Michelle Kho, PT, PhD
American Thoracic Society (ATS) @atscommunity.bsky.social · 02/07/2025
Register for the 14th Annual Johns Hopkins Critical Care Rehabilitation Conference. This two-day Conference features 16 multi-disciplinary speakers from critical care medicine, respiratory therapy, nursing, psychology, PT, and more, Learn more: hopkinscme.cloud-cme.com/course/cours...
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Reposted by Michelle Kho, PT, PhD
Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 02/07/2025
Just got an email from a colleague that her dying patient wants to see the ocean one last time. Made me sad. Fingers crossed that they can make it happen with my advice from 6000 miles away… @3wishesprogram.bsky.social
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 29/06/2025
Today's Paper of the Day is: Demystifying Volume Status. An Ultrasound-Guided Physiologic Framework. criticalcarereviews.com/latest-evid… Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
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Reposted by Michelle Kho, PT, PhD
Jack Iwashyna @iwashyna.bsky.social · 26/06/2025
“On Not Betraying Our Trainees, Especially Now” I won an Extraordinary Achievement Award from the Critical Care Assembly last month The @atscommunity.bsky.social premier journal @atsblueeditor.bsky.social TODAY published the remarks I made on that occasion www.atsjournals.org/doi/10.1164/...
atsjournals.org
On Not Betraying Our Trainees, Especially Now | American Journal of Respiratory and Critical Care Medicine | Articles in Press
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Reposted by Michelle Kho, PT, PhD
Patricia Liaw @patricialiaw.bsky.social · 25/06/2025
Outstanding talks at @isth.org Scientific and Standardization Committee on Models of Thrombosis & Hemostasis! Topics on IVC stenosis, platelet depletion/transfusion, viscoelastic testing, preclinical vs. human coagulation assays. 🩸@jthjournal.bsky.social
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 25/06/2025
Palliative care in the ICU: from oxymoron to standard of care CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evide...
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 23/06/2025
🙏
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 24/06/2025
The ALBICS-AKI trial was published recently in JAMA Surgery during #CCR25 The recording of the presentation is available from CCR Down Under criticalcarereviews.com/meetings/ccr... Paper -> jamanetwork.com/journals/jam...
jamanetwork.com
Albumin Infusion and Kidney Injury in Cardiac Surgery Patients
This randomized clinical trial evaluates the use of postoperative 20% albumin infusion vs usual care in high-risk cardiac surgery patients.
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Reposted by Michelle Kho, PT, PhD
3 Wishes Program @3wishesprogram.bsky.social · 16/06/2025
So much beauty, time, and attention to detail goes in creating these hand molds. This one is for a husband and wife holding hands for final time. #Kindness #EOLcare
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Reposted by Michelle Kho, PT, PhD
Marion Campbell @marionkcampbell.bsky.social · 16/06/2025
At #CCR25, we saw some trials use a #CompositeOutcome (an endpoint that combines more than one outcome into a single measure) & also saw some of the problems these can throw up. I have discussed these before but thought it would be useful to revisit 1/9 #MethodologyMonday #120
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 16/06/2025
Today's Paper of the Day is: The broad spectrum of malignant syndromes criticalcarereviews.com/latest-evid… Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
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Michelle Kho, PT, PhD @khome1.bsky.social · 14/06/2025
INdex @ccctg.bsky.social @criticalcarereviews.com
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Reposted by Michelle Kho, PT, PhD
JAMA @jama.com · 13/06/2025
From JAMA Neurology: CT perfusion and CT angiography showed less than optimal accuracy for confirming death by neurologic criteria. #CCR25 @criticalcarereviews.com ja.ma/3TeogPR
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Reposted by Michelle Kho, PT, PhD
JAMA @jama.com · 13/06/2025
📢 #CCR25 Highlights: We've compiled the JAMA and JAMA Neurology papers presented at this year’s meeting. Explore the thread! 👇 Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting. ja.ma/4dV8SkX
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Reposted by Michelle Kho, PT, PhD
NEJM.org @nejm.org · 13/06/2025
In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results: nej.md/4kC2a67 @criticalcarereviews.com #CCR25
A graph showing the cumulative probability of successful liberation from ventilation and of death before successful liberation.
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Reposted by Michelle Kho, PT, PhD
Canadian Critical Care Trials Group (CCCTG) @ccctg.bsky.social · 13/06/2025
INdex Trial Results, coming up at Critical Care Reviews in Belfast! Watch at 10:20AM Eastern for those tuning in from Canada. Free livestream: criticalcarereviews.com #CCR25
criticalcarereviews.com
Home
The most up-to-date critical care website in the world
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 13/06/2025
Lauralyn McIntyre & Monica Taljaard summarise the FLUID trial presented yesterday at the Critical Care Reviews Meeting 2025 and simultaneously published in the @nejm.org www.nejm.org/doi/full/10....
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Reposted by Michelle Kho, PT, PhD
Canadian Critical Care Trials Group (CCCTG) @ccctg.bsky.social · 13/06/2025
Happening now! INdex Study Results at #CCR25. Catch the livestream: criticalcarereviews.com
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Reposted by Michelle Kho, PT, PhD
Canadian Critical Care Trials Group (CCCTG) @ccctg.bsky.social · 13/06/2025
PROMIZING Trial Results presented at #CCR25 in Belfast. Congrats to Dr Karen Bosma and the PROMIZING team. See the full trial results in @nejm.org
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Reposted by Michelle Kho, PT, PhD
Critical Care Reviews @criticalcarereviews.com · 13/06/2025
#PROMIZINGtrial results are in - no difference in time to successful liberation from mechanical ventilation between proportional-assist ventilation and pressure support ventilation #CCR25
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Michelle Kho, PT, PhD @khome1.bsky.social · 13/06/2025
PROMIZING RCT@ccctg.bsky.social @criticalcarereviews.com #CCR25
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Reposted by Michelle Kho, PT, PhD
Marion Campbell @marionkcampbell.bsky.social · 13/06/2025
With all the cluster crossover designs being presented at #CCR25 I thought it might be useful to re-share the short explainer of the designer that I posted a couple of weeks ago
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