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Bharath Kumar

@bharathkumartv.bsky.social
23 followers 39 following 30 posts

Intensivist|Trialist|Ph.D. candidate @amsterdamumc.bsky.social Live and work in Chennai; Bangalorean at heart.

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Reposted by Bharath Kumar
NEJM.org @nejm.org · 29/08/2026
In patients with suspected acute coronary syndrome without myocardial infarction, routine CT coronary angiography did not result in a lower incidence of myocardial infarction or death from a cardiac cause than standard care. Full TARGET-CTCA trial results: nej.md/4wH7Yk7 #ESCCongress
A figure from the Original Article "Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain." The trial name, TARGET-CTCA, is in parentheses after the title. The figure shows the incidence of myocardial infarction or death from a cardiac cause. The trial results are being presented at the European Society of Cardiology Congress 2026. The logo of the New England Journal of Medicine is at the bottom.
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Bharath Kumar @bharathkumartv.bsky.social · 15/05/2026
Our paper evaluating the association between sex (as assigned at birth) and clinical outcomes in critically ill patients is now published in Critical Care Medicine : journals.lww.com/ccmjournal/a...
journals.lww.com
Association Between Sex and Clinical Outcomes for... : Critical Care Medicine
luded adult (≥ 16 yr) patients admitted to ICUs in the IRIS. Interventions: None. Measurements and Main Results: The primary exposure was sex at birth, and the primary outcome was ICU mortality....
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Bharath Kumar @bharathkumartv.bsky.social · 23/12/2025
Last Friday, I successfully defended my Ph.D. at University of Amsterdam's Agnietenkapel. Here is the link to my Ph.D. dissertation: dare.uva.nl/search?ident...
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Reposted by Bharath Kumar
NEJM.org @nejm.org · 04/12/2025
In a pragmatic trial conducted in general medical wards with limited diagnostic and therapeutic resources in Kenya, glucocorticoids reduced mortality in patients with community-acquired pneumonia. Full SONIA trial results: nej.md/47glh02 #MedSky #PulmSky #CriticalCare
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 13/11/2025
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Bharath Kumar @bharathkumartv.bsky.social · 12/11/2025
Incredible global effort- glad sites from India could collaborate- can't wait to see the results! Congratulations @dogicuma.bsky.social and the entire global MegaROX team 🙏
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 11/11/2025
#MegaROXtrial 27 to go. 39973 enrolled.
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Reposted by Bharath Kumar
Intensive Care Medicine Journal @intenscaremed.bsky.social · 06/11/2025
ICU-acquired weakness is common; protocolised active rehabilitation helps, while higher enteral protein alone shows no outcome benefit. Priorities include early prognostic markers, better diagnostics and personalised care. zurl.co/BBlDf
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 06/11/2025
The #MegaROXtrial has fewer than 150 patients left to enrol
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Reposted by Bharath Kumar
Critical Care Reviews @criticalcarereviews.com · 06/11/2025
The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective CCR Journal Watch criticalcarereviews.com/latest-evid…
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 05/11/2025
The #MegaROXtrial has 39800 patients which leaves only 200 left to enrol
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Bharath Kumar @bharathkumartv.bsky.social · 08/10/2025
Our paper on a core outcome measurement set for clinical trials in dengue is now published in The Lancet Infectious Diseases : www.thelancet.com/journals/lan...
thelancet.com
Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE)
Dengue, caused by any one of four distinct virus serotypes, is the most rapidly spreading mosquito-borne viral disease worldwide. It is a primary arboviral infection with increasing global incidence, ...
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Reposted by Bharath Kumar
Otavio Ranzani @otavioranzani.bsky.social · 25/09/2025
Dengue outbreak in Sudan 👇. We need better tools and investment to tackle dengue
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Marion Campbell @marionkcampbell.bsky.social · 17/09/2025
This👇 …. often unseen but crucial role
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 17/09/2025
##MegaROXtrial 1600 to go
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Reposted by Bharath Kumar
Marion Campbell @marionkcampbell.bsky.social · 08/09/2025
I seem to have been discussing pilot and feasibility studies a lot this week. One question often asked is how big should my pilot/feasibility study be? 1/6 #MethodologyMonday #124
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Paul Young @dogicuma.bsky.social · 28/08/2025
The #MegaROXtrial has reached 37851 enrolments. 38k likely next week and 40k on the cards for Nov.
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Reposted by Bharath Kumar
Marion Campbell @marionkcampbell.bsky.social · 18/08/2025
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg  treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9 #MethodologyMonday #123
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Paul Young @dogicuma.bsky.social · 17/08/2025
#MegaROXtrial 2.5K to go
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Bharath Kumar @bharathkumartv.bsky.social · 14/08/2025
I am delighted to be joining the Editorial Board of @bmj.com as a freelance Clinical Editorial Advisor. I look forward to bringing acute/critical care and LMIC perspectives to the editorial decision-making table.
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Reposted by Bharath Kumar
Otavio Ranzani @otavioranzani.bsky.social · 14/08/2025
One of the most elegant and sucint text on global critical care research inequity #DecolonizeGH
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Reposted by Bharath Kumar
European Society of Intensive Care Medicine @esicm.bsky.social · 01/08/2025
🚨 The #ESICM 𝟯𝗚 𝗚𝗿𝗮𝗻𝘁 – 2nd Call is 𝗢𝗣𝗘𝗡 𝘂𝗻𝘁𝗶𝗹 𝟮𝟳 𝗔𝘂𝗴! 💶 €300K for research on 𝗿𝗮𝗽𝗶𝗱 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 𝗶𝗻 𝘁𝗵𝗲 #ICU, in collaboration with bioMérieux! We invite bold, hypothesis-driven proposals with real-world impact on #AMR & patient outcomes. 🔗 www.esicm.org/3g-giant-gre... #ICUresearch
esicm.org
Giant Great Grant - "3G" - ESICM
The 2nd edition of the 3G project is now open - thanks to the support of Biomérieux. We call on all healthcare professionals to submit a proposal focusing on FAST ID/AST to implement antimicrobial stewardship in critically ill patients.
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 30/07/2025
The 37000th patient was enrolled in the #MegaROXtrial in Casey Hospital, Australia at 05:01am local time. 3K to go.
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 26/07/2025
The #MegaROXtrial has 36907 patients enrolled. 37K is days away. We will get to 40K in the last quarter of 2025.
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Reposted by Bharath Kumar
Marion Campbell @marionkcampbell.bsky.social · 21/07/2025
We often now hear the term “Bayesian borrowing” in trials. But what is Bayesian borrowing and what are the pros and cons around its use? 1/6 #MethodologyMonday #122
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Madhu Pai, MD, PhD @madhupai.bsky.social · 17/07/2025
Heat waves make the news when they impact Global North countries Constant, extreme heat is a daily fact of life for billions in the Global South
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 12/07/2025
36500 patients enrolled in the #MegaROXtrial. Only 3500 to go.
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Bharath Kumar @bharathkumartv.bsky.social · 10/07/2025
Our pilot trial evaluating dexamethasone in patients hospitalised with dengue is now active at 5 hospitals and we enrolled our 5th trial participant today. We are funded by @uoftcities.bsky.social and the University of Toronto India foundation. Trial sponsored by @georgeinstitute.bsky.social
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Reposted by Bharath Kumar
Marion Campbell @marionkcampbell.bsky.social · 07/07/2025
Over recent weeks I have heard about some trials struggling with the phenomenon known as “Lasagne’s Law.” I’ve flagged this issue before, but always good to revisit it and discuss what can be done to minimise it 1/7 #MethodologyMonday #121
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Bharath Kumar @bharathkumartv.bsky.social · 04/07/2025
This is a fantastic opportunity: isaric.org/capacity/sci... Please share widely 🙏
isaric.org
ISARIC Leadership Programme for Scientists | ISARIC
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Reposted by Bharath Kumar
The BMJ @bmj.com · 03/07/2025
A recent BMJ investigation raised fresh concerns over the integrity of the clinical trials that underpinned the approval of blockbuster drug ticagrelor. In our latest podcast, we delve into this issue Listen on Apple podcasts.apple.com/no/podcast/t... Or Spotify open.spotify.com/episode/1qG5...
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Anaesthesia @anaesjournal.bsky.social · 01/07/2025
Anaesthesia LMIC-based Editorial Fellowship Applications due NOW! #AnSky
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 25/06/2025
Patient #36000 has been enrolled into the #MegaROXtrial
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 23/06/2025
The ##MegaROXtrial will reach 36000 participants by the end of the week leaving only 10% to go.
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Reposted by Bharath Kumar
Paul Young @dogicuma.bsky.social · 18/06/2025
I have been researching oxygen therapy in ICU for many years. Here is something, that I have noticed. Apart from one small single centre trial (Oxygen-ICU), the point estimate effect on mortality for every trial in heterogeneous ICU patients has favoured liberal oxygen.
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Bharath Kumar @bharathkumartv.bsky.social · 16/06/2025
Our paper evaluating 'persistent critical illness' among patients in India is now published in CCM @sccmjournals.bsky.social journals.lww.com/ccmjournal/a...
journals.lww.com
Persistent Critical Illness Among Intensive Care Patients... : Critical Care Medicine
rt study. Setting: Fifty-six ICUs in India belonging to the Indian Registry of Intensive Care. Patients: Adult critically ill patients. Interventions: None. Measurements and Main Results: ...
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Reposted by Bharath Kumar
Adam Grant @adamgrant.bsky.social · 15/06/2025
Dads are spending 3-4x as much time with their kids as their dads did with them. When father figures are engaged, kids show better cognitive development, boys have fewer behavioral problems, and girls have fewer emotional problems. Every child deserves strong parental bonds.
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Marion Campbell @marionkcampbell.bsky.social · 11/06/2025
#CCR25 … here we go! Three days of deep discussion of the top trials in critical care. If you are not in the room, do connect via livestream - see criticalcarereviews.com
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Bharath Kumar @bharathkumartv.bsky.social · 11/06/2025
Superb couple of days attending the Dark Arts of Clinical Trials in Belfast. High-quality discussions around the art of leading academic clinical trials in critical care medicine. Grateful to Lisa Higgins and Steve Webb for this amazing opportunity🙏
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Reposted by Bharath Kumar
Segun Olusanya (He/Him) @drfreeze.bsky.social · 11/06/2025
Could we have more #ccr25 content on Bluesky please? While I still have access to the other place, it’s not much fun seeing random X crap in between thoughtful takes about the utility of NFL
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JAMA @jama.com · 10/06/2025
Applications for the JAMA Network Peer Review Academy open July 7. 📅 This academy offers early-career researchers an opportunity to: ✅Develop high-quality peer reviews ✅ Gain behind-the-scenes insight into the editorial process ✅ Learn directly from JAMA Network editors ja.ma/4mTLcS8
Build your peer review expertise. Applications open July 7.
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Reposted by Bharath Kumar
Critical Care Reviews @criticalcarereviews.com · 07/06/2025
🚨 12 Major Critical Care Trials 🚨 🌟 Global experts 🗣️ Live discussion 📺 Join the free livestream of #CCR25 – where critical care meets cutting-edge evidence 💡 🌍 Streaming the latest trials & analysis you don't want to miss 📊🧪 🔗 criticalcarereviews.com/meetings/cc…
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Jonathan Howard @joho.bsky.social · 09/05/2025
Dr. Vinay Prasad got famous “telling” the Medical Establishment to do RCTs and making juvenile, vulgar videos when they failed. He thought this was a real accomplishment. Now it’s his job to do those RCTs and our job to tell him what to do. My latest. sciencebasedmedicine.org/dr-vinay-pra...
sciencebasedmedicine.org
Dr. Vinay Prasad is Now the Medical Establishment. It’s His Job to Run RCTs, and It’s Our Job to Call Him a Lying Piece of $#!& if He Fails.
"I wish Vinay all the best for his new role. It's a whole new state of play when the buck stops with you."
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Bharath Kumar @bharathkumartv.bsky.social · 05/05/2025
Powerful conversation, specifically the idea of ethical fading- all pervasive, especially in the healthcare industry. www.youtube.com/watch?v=f-7W...
youtube.com
Trevor Noah Makes My Brain Hurt | A Bit of Optimism Podcast
YouTube video by Simon Sinek
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Reposted by Bharath Kumar
Ola Løkken Nordrum @olaln.bsky.social · 02/05/2025
It’s time to ban SUVs. My letter in the Irish Times yesterday. #BanSUVs #SUVBan
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Bookshelfie ⭐️ @bookshelfie.bsky.social · 02/05/2025
#booksky
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Otavio Ranzani @otavioranzani.bsky.social · 30/04/2025
Are you aware of these numbers? More than 35k cases of measles in Europe and associates in 2024 We need to protect everyone. Please, get vaccinated
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Bharath Kumar @bharathkumartv.bsky.social · 28/04/2025
undark.org/2025/04/23/o...
undark.org
The Dangerous Illusion of Climate Resilience
Opinion | The latest floods, wildfires, and other disasters reveal the flaws of adaptation as the main response to climate change.
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Reposted by Bharath Kumar
Maj-Brit Nørregaard Kjær @maj-brit.bsky.social · 07/01/2025
A consensus-based core outcome set for adult general ICU patients was developed and internationally validated. Published today in Critical Care Medicine #CritCareMed Thanks to all collaborators (co-authors) journals.lww.com/ccmjournal/a...
journals.lww.com
A Core Outcome Set for Adult General ICU Patients : Critical Care Medicine
nts exist, for example, respiratory failure, delirium, and COVID-19, but not for ICU patients in general. Accordingly, we aimed to develop a core outcome set for adult general ICU patients. Design: ...
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