iiinova — where your digital self keeps evolving

Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 22/01/2026

A new Crnic Institute study reveals people with Down syndrome show consistent signs of liver dysfunction across the lifespan.With support from the Global Down Syndrome Foundation, this research offers hope for simple, actionable interventions to support better health. Learn more at bit.ly/4jQOLHD.

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 22/09/2025

Congratulations to Dr. Paula Arya, Dr. Joaquin Espinosa and Dr. Kelly Sullivan for leading a new study published in iScience entitled "Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model." Read more at bit.ly/3Io31cK.

"Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model," published in iScience, a Cell Press Journal

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 19/09/2025

As Postdoc Appreciation Week ends, we celebrate our three outstanding postdocs at the Crnic Institute. Thank you, Dr. Brian Niemeyer, Dr. Sara Sherman and Dr. Ariel Timkovich, for your invaluable contributions. Our mission to advance Down syndrome research wouldn’t be possible without you!

Postdoc Appreciation Week
Brian Niemeyer, PhD
Sara Sherman, PhD
Ariel Timkovich, PhD

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 12/08/2025

We need research heroes! Researchers at the Crnic Institute and Boys Town National Research Hospital are working together to better understand hearing and balance in people with Down syndrome from September 8-13 at Children's Hospital Colorado. Learn more: bit.ly/HearinginDS

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 09/08/2025

Registration is open for the annual Crnic Institute Down Syndrome Research Symposium on September 15, 2025! This in-person event will take place on the 2nd floor of the Anschutz Health Sciences Building. Register today at bit.ly/DS-Symposium.

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 01/08/2025

Congratulations to Dr. Kelly Sullivan, director of the Crnic Institute’s Experimental Models Program and associate professor at @cupediatrics.bsky.social‬, on presenting ”The Interferonopathy of Down Syndrome,” and to Rachel Shropshire for winning Top Student Poster at this year’s DSMIG Symposium!

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Kelly Sullivan @kellydsullivan.bsky.social · 30/07/2025

The 2026 Program will heavily emphasize co-occurring conditions and tissue systems affected by T21. We encourage diversity in the composition of symposia speakers with respect to geography, academic rank, and gender. Society members at all career stages are welcome to submit symposia.

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Kelly Sullivan @kellydsullivan.bsky.social · 30/07/2025

The theme for the 6th International Conference of the Trisomy 21 Research Society will be, “T21: Insights from Across the Lifespan”. Each symposium will consist of four speakers in a 2-hour block and should include both basic and translational components to foster discussion among research teams.

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Kelly Sullivan @kellydsullivan.bsky.social · 29/07/2025

Planning for next years T21RS International Conference in Denver is under way! Call for Symposia will open on August 15. If you have any questions, please don't hesitate to reach out. www.t21rs.org/5th-t21rs-in...

t21rs.org

6th T21RS International Conference – Colorado 2026 – T21RS

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Reposted by Kelly Sullivan

Ed Chuong @edchuong.bsky.social · 17/07/2025

Are you bravely deciding to do a postdoc in the US? And also interested in some combination of genomics, immunology, and transposons? If so, consider applying to my lab at the BioFrontiers Institute in Boulder, Colorado! jobs.colorado.edu/jobs/JobDeta... 🧪🧬 #TESky #interferosky

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CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 17/07/2025

New research opportunity! Researchers at the Crnic Institute and Boys Town National Research Hospital are working together in Dallas, TX, to better understand hearing and balance in people with Down syndrome. Compensation is provided. Learn more and schedule an appointment at bit.ly/HearinginDS.

Research participant taking a hearing test wearing headphones.

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Reposted by Kelly Sullivan

Seth Bordenstein @symbionticism.bsky.social · 14/07/2025

Some news....Rome is not fully burned down. T32 PhD Training Grant was officially awarded, and two weeks ago, the NIH offered more support than requested to increase the # trainees in the unique program. Office chair with me in it levitated. Calling Microbime PhD'ers to @psumbiome.bsky.social 🎓

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Tracy Bale @thebalelab.bsky.social · 14/07/2025

NIH and FDA hosted a workshop on July 7 on efforts to reduce the use of animal models in research, NIH has formally announced a policy change. The agencies have invited comments through the workshop’s webpage. PLEASE COMMENT. The portal will be open until 5pm ET on Monday, July 14 (TODAY).

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Kelly Sullivan @kellydsullivan.bsky.social · 10/07/2025

Congratulations to Dr. Jason Wilson of @cuhmggp.bsky.social on successfully defending his dissertation yesterday! You can check out some of his work here: www.biorxiv.org/content/10.1...

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Reposted by Kelly Sullivan

Rep. Joe Neguse @neguse.house.gov · 23/05/2025

Grateful to meet with students from CU Boulder’s CU in DC program. Appreciated their thoughtful and insightful questions!

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Nick Garcia @nwgarcia.bsky.social · 14/05/2025

Maybe someone needs to say this out loud, but computers can't model the physiology of a living organism because we don't know how many of the parts of an organism work, which is uhhh... why we do the research with the animal models?

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Reposted by Kelly Sullivan

University of Colorado Anschutz @cuanschutz.bsky.social · 23/04/2025

Thank you Congressman @crow.house.gov for visiting the #CUAnschutz Medical Campus to learn more about our latest breakthroughs and the vital role of federal funding in driving lifesaving new medical discoveries.

CU Anschutz Chancellor Don Elliman, U.S. Representative Jason Crow and Vice Chancellor for Research Thomas Flaig, MD, sit at the roundtable

Representative Jason Crow looks into a microscope during a tour on the CU Anschutz campus.

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 22/04/2025

It was a pleasure to have Kristina Sisneros from Regis University for her GLOBAL Inclusive Program Internship! Thank you to GLOBAL for supporting this amazing opportunity, and congratulations to Kristina on all her hard work.

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Reposted by Kelly Sullivan

Dr. Elise Gornish @restorecal.bsky.social · 16/04/2025

Hi Folks! Myself and the Barberan Lab at U of A are still looking for a PhD student to work on an NSF funded project exploring effects of fire and invasion on soil microbes. We are looking for someone to start in Fall! SOON! Email me if you are interested! PLS Repost! @EsaSeeds

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Benjamin McKean @blmckean.bsky.social · 10/04/2025

striking to me that this interview ends with him plaintively pleading for other university leaders to speak up: "I don’t think this is all about Princeton. It’s about what’s happening in the United States. I think this would be so much stronger if many more of my fellow presidents were speaking up."

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MindCrowd 🧠 @mindcrowd.bsky.social · 21/03/2025

Are you wearing different socks to celebrate #WorldDownSyndromeDay ? Join in!!! It's fun!!!

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Reposted by Kelly Sullivan

Heide Ford Lab @heidefordlab.bsky.social · 20/03/2025

Was very excited to host Senator Hickenlooper in my lab this past week, as well as be involved in a panel discussion around the important of federal funding for science! coloradosun.com/2025/03/19/n...

coloradosun.com

Funding cuts to CU-Anschutz could erase years of medical research contributed by patients, advocates fear

NIH funding cuts could halt years of progress on medical research contributed by patients at Colorado's CU-Anschutz campus.

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Kelly Sullivan @kellydsullivan.bsky.social · 20/03/2025

Tomorrow is World Down Syndrome Day (3/21)! We have made great strides in understanding Down syndrome and improving healthspan for this amazing community, but there is much work to be done. Honored to be part of the Trisomy 21 Research Society Executive Board. www.thelancet.com/journals/lan...

thelancet.com

Advocating for increased awareness and research on Down syndrome

World Down Syndrome Day, observed annually on March 21 and recognised by the UN since 2012, aims to raise awareness of Down syndrome to help people better understand and support those with the conditi...

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 18/03/2025

Be part of research progress! Our researchers are working with @boystownhospital.bsky.social to learn more on balance and hearing in #Downsyndrome. This single appointment includes balance exercises and a hearing test with results given on site. Learn more: bit.ly/3R4Ogwl

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 17/03/2025

Join us this Wednesday, March 19th, for our monthly Supergroup presentations! This event is open to all Crnic Institute Members. If you are not a member and are interested in data science presentations, visit bit.ly/CrnicMember. @caylajewett.bsky.social

Cayla Jewett, PhD
Postdoctoral Fellow
Pearson Lab
Department of Cell and Developmental Biology
University of Colorado Anschutz

Presentation: Copy number control from chromosomes to centrosomes
Bailey McCurdy, BS
PhD Candidate
Pearson Lab
Department of Cell and Developmental Biology
University of Colorado Anschutz

Presentation: Uncovering centriolar uncapping defects in Trisomy 21
Crnic Institute Supergroup
March 19, 2025 | 11:30 a.m. - 1 p.m.

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Kelly Sullivan @kellydsullivan.bsky.social · 15/03/2025

Tough loss. Good to see them fight back again.

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Reposted by Kelly Sullivan

Kevin M. Kruse @kevinmkruse.bsky.social · 15/03/2025

Ugh. Glad they made it a game at least.

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Reposted by Kelly Sullivan

CU Anschutz Developmental Biology @cudevbio.bsky.social · 14/03/2025

One of our stars defended today! Dr. @luulitran.bsky.social from the @thefrancolab.bsky.social lab gave a stellar seminar describing her deep, insightful, and highly productive investigations of the neuron-glia switch. #devbio @cupediatrics.bsky.social @cuanschutz.bsky.social

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 13/03/2025

We need to research heroes! Our researchers are partnering with researchers at Boystown National Hospital from April 12-18 in Boston, MA, to better understand hearing and balance in #Downsyndrome. This study is a single appointment, including a hearing test and biological sample. bit.ly/3R4Ogwl

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 11/03/2025

#DYK as many as 9 in 10 people with Down syndrome develop Alzheimer’s disease? If you or a loved one is healthy & between the ages of 25-55 with Down syndrome, visit trcds.org.

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Reposted by Kelly Sullivan

Heide Ford Lab @heidefordlab.bsky.social · 06/03/2025

Excited to post this op-ed published in the front porch and written by the talented Aimee Bernard in conjunction with the basic science chairs. Opinions are our own. frontporchne.com/opinion-the-...

frontporchne.com

Opinion: The Critical Need for Science Funding | Front Porch

As chairs of the basic science departments, we are compelled to address a matter of utmost urgency: the critical need for funding in scientific research. In an era where scientific advancements hold t...

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 24/02/2025

Members of the Human Trisome Project - Latin America Network (HTP-LAN) team recently traveled to Colorado for a week of collaboration and education! We are proud of our team for gaining valuable skills to support Down syndrome research procedures across the network.

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Reposted by Kelly Sullivan

CU Anschutz Linda Crnic Institute for Down Syndrome @crnicinstitute.bsky.social · 25/02/2025

A new publication from the Crnic Institute team in collaboration with Dr. Jonathan Santoro at Children's Hospital Los Angeles (CHLA) reveals new insights about the molecular and immune changes associated with Down Syndrome Regression Disorder (DSRD). bit.ly/4iawGSS

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Reposted by Kelly Sullivan

Ally Nguyen @allynguyen.bsky.social · 19/02/2025

We are hiring! Looking for a Research Assistant to join our group at CU Anschutz in Denver studying genome integrity nguyenlab.org. Individuals will lead their own project as well as help support basic lab function! cu.taleo.net/careersectio...

nguyenlab.org

Nguyen Lab

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Reposted by Kelly Sullivan

University of Colorado Anschutz @cuanschutz.bsky.social · 17/02/2025

“It’s really an elaborate infrastructure that’s required to do this research. One of the things that concerns me is the magnitude and rapidity of these changes.” VC for Research Tom Flaig, MD, recently spoke to @cbsnews.com about the potential impact the proposed NIH cuts could have on our campus.

cbsnews.com

Colorado's large medical research community deals with attempts to cut federal funding

Colorado's medical research community is looking at how to handle the potential of cuts to research grant money that it receives from the National Institutes of Health.

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Kelly Sullivan @kellydsullivan.bsky.social · 14/02/2025

Very proud to be a member of this team. A huge group effort to improve the lives of those with Down syndrome. Thank you to everyone that has helped us along the way.

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 12/02/2025

Well said @dereklowe.bsky.social. Academia produces two vital products: (1) knowledge, and (2) human capital that knows how to use it. If we can’t train enough young creative US scientists to fulfill biopharma industry needs… “I think they're being short-sighted, because fear does that to you.”

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Craig Kaplan @triggerloop.bsky.social · 09/02/2025

Kids will suffer because of this. This is an outrage.

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Jonathan Eisen @phylogenomics.bsky.social · 09/02/2025

Attention Attention Attention If anyone knows clinicians or patients who have knowledge of pediatric patients with the very rare cancer interdigitating dendritic cell sarcoma (IDCS) or other (non-LCH) dendritic or histiocytoc sarcomas please contact Sri

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Sarah Tishkoff, PhD @sarahtishkoff.bsky.social · 08/02/2025

Apologies for this long post I put together to explain to non-scientists the impact of NIH cuts: Last night, an “atomic bomb” was dropped on the biomedical science community. We were informed that effective immediately, indirect costs on NIH grants (both current and future) would be fixed at 15%.

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Zoe McElligott @nanopharmnc.bsky.social · 22/01/2025

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

unitedformedicalresearch.org

NIH In Your State - United For Medical Research

Select a state on the map to see the impact of NIH funding across America.

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Reposted by Kelly Sullivan

PLOS Biology @plosbiology.org · 16/01/2025

‘Big data’ generated from outsourced or centralized facilities often lacks methodological information. This Perspective outlines how and why researchers, service providers, and other parties should report on #methodology and sample #metadata to improve scientiﬁc #reproducibility. plos.io/42hSck6

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Bruce Appel @bruceappel.bsky.social · 30/12/2024

Our first manuscript on maternal nutrition and development, which was driven entirely by postdoc Katie Ranard, is now out. @cudevbio.bsky.social #devbio doi.org/10.1016/j.jl...

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Kate Miroshnikova @katemiro.bsky.social · 08/01/2025

Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin

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CU Anschutz Developmental Biology @cudevbio.bsky.social · 03/01/2025

Meet the author: Dr. Katie Ranard, a NINDS F32-funded postdoc in the Appel lab, just published her first manuscript describing use of zebrafish to model the impact of maternal nutritional deficiency on brain develepment. doi.org/10.1016/j.jl... 🧪🧠 #zebrafish #devbio

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