iiinova — where your digital self keeps evolving

Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Richard Unwin @rdunwin.bsky.social · 24/10/2025

This is accurate. There's a valley of death between 'good academic research' and 'ready for investment'. Every project at that stage is risky, and because there's not much money instututions cherry pick and become risk averse. If you wanna win the lottery, buy more tickets.

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

The Company of Biologists @biologists.bsky.social · 15/10/2025

1946: The Quarterly Journal of Microscopical Sciences is transferred to the Company. In 1966, QJMS is renamed Journal of Cell Science @jcellsci.bsky.social. Read JCS’s 100-anniversary article collection: bit.ly/46RvL5N

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

As with last evening’s panel write-up, all views here are my interpretation of the discussion - any errors are mine, not the panellists! What a great day of research and networking! #CrickCancerConf

A vibrant welcome slide for the “5th Crick International Cancer Conference,” held 5–7 October 2025. The background features a colourful microscopic image with cellular structures in red, green, and blue hues.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

– Interview prep is vital: research statement, job talk, chalk talk – Think beyond science: connection to colleagues and institute culture matters – Industry is a valid route; there too interviews are rigorous and science-driven #CrickCancerConf #ResearchCareers #AcademicPathways

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

– When pitching proposals: pair a grounded project with a bold long-term vision – Diversify from your supervisor; open dialogue beats competition Practical Advice: – Build a strong network; peers matter as much as PIs – Explore & develop skills in teaching, editorial, and community building

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

Key Takeaways: – No fixed ideal postdoc length: passion, networks, and adaptability matter most – Productivity per time unit counts, even if papers aren’t high-impact – While a postdoc focus on lab goals not your niche: communication with mentors is critical at the transition #PostdocToPI

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

🗣️ Day 2 ended with another discussion panel, this time on the postdoc to PI career transition. Our panellists: – Anna Obenauf – Stefani Spranger – Guillaume Jacquemet They shared candid insights on navigating the leap from postdoc to independence. #CrickCancerConf #ResearchCareers #TeamScience

A panel titled “Navigating the post-doc to PI transition” is underway. Three panellists — Anna Obenauf, Stefani Spranger, and Guillaume Jacquemet - are seated on stage. Our panel host stands in the middle addressing the audience. The screen behind them displays the session title and panellist names.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

🩺 Clinician–scientist career pathways at the Crick: 1. PhDs for qualified clinicians 🔗 crick.ac.uk/careers-and-study/clinical-fellows 2. PhDs for early-career clinicians 🔗 colcc.ac.uk/clinical-research-training-fellowships-crtf 3. Postdoc fellowships for clinicians. Will open March 2026

crick.ac.uk

Clinical fellows

Opportunities for clinicians to develop their research careers at the Crick.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

Well I was too busy talking and listening today to post during the event so catching up this evening. This informational slide may help clinicians looking for a research opportunity! (Links in next post) #CrickCancerConf #ClinicianScientist #PhDForClinicians #PostdocFellowship #ResearchCareers

A slide titled “Opportunities for clinicians at the Crick” lists three fellowship schemes: Crick doctoral fellowships for clinicians (apply by 14 Nov 2025), CRUK City of London Centre clinical research training fellowships (apply by 5 Nov 2025), and Crick postdoctoral fellowships for clinicians (open March 2026). Each includes a brief description and relevant URLs.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

Congratulations! Immunology is certainly the topic of today - I’m seeing this news whilst in an immunology session at #CrickCancerConf!

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

CRUK Convergence Science Centre @crukconvergence.bsky.social · 06/10/2025

Congratulations to our 2025 Development Fund awardees! 🎉 From new detection tools to targeted nanotech therapies, these seed funded projects explore bold ideas to improve cancer diagnosis & treatment. 👉 bit.ly/4gV38tf @icr.ac.uk @imperialcollegeldn.bsky.social @imperialsandc.bsky.social

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 06/10/2025

Heading in for day 2 of #CrickCancerConf Session themes today are, “Inflammation and cancer” this morning, and “Therapy resistance” this afternoon. A top lineup of speakers again, and I’m so looking forward to exploring more posters too. Reach out if attending and a conversation might help you!

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🧵 All views shared here are my interpretation of the discussion. If I’ve misrepresented anything, the fault’s mine - not the panellists’. Overall, a thought-provoking day at #CrickCancerConf - grateful for the openness, ambition, and global perspective.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

Prevention vs cure? Both essential - and prevention of recurrence is underexplored Can cancer learn from CVD? Maybe - but cancer’s complexity is a different beast #FutureOfScience #CancerResearch #CrickCancerConf #CancerPrevention

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🔍 Final panel themes: #OpenScience: enthusiasm for sharing, but metadata is key - raw data alone isn’t enough Are we missing the bigger picture? Precision medicine has narrowed focus, but toxicity and recurrence remain major challenges #CrickCancerConf

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

Discovery science still matters - and needs space for creativity Future labs may be 50:50 wet/dry scientists All wet-lab researchers should learn robust data analysis (e.g. R) Clinicians + data scientists are key to future teams #CrickCancerConf #TeamScience #DataScience

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🧪 The panel tackled big questions on research careers and data science: PhD timelines vs team science: 3–4 years rarely yields a full high-impact paper Solutions? Value smaller papers, fund longer-term projects, invest in permanent technical specialists #TeamScience #PhDTraining #ResearchCareers

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

The panel explored questions from the audience alongside a number of spiked questions (shown). Interestingly, addressing cancer inequalities was asked first. Replies: we need to understand causes, need to sample less genetically homogeneous populations, & tackle globally. #CancerInequalities

Four panellists sit on stage under the title “The Future of Cancer Research.” A projected slide lists six suggested questions for discussion:
1. What area excites you most?
2. What technologies do we need?
3. Prevention or Cure? Where should we focus?
4. What is the role of AI? What are the risks?
5. What is the ideal lab unit? Ratio of students, post-docs, clinicians, & tech specialists?
6. How should we minimise inequalities in outcomes?

The slide is part of a structured panel session moderated by Erik Sahai, with panellists Sarah-Maria Fendt, Jose Adrover, and Momo Bentires-Alj. The image captures the reflective and forward-looking tone of the discussion.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🗣️ Panel: “The Future of Cancer Research” Erik Sahai opened sharing this timeline of cancer research milestones: 🔗 www.cancer.gov/research/pro... Our Panellists: Sarah-Maria Fendt, Jose Adrover, Momo Bentires-Alj, Erik Sahai #CrickCancerConf #CancerResearch #FutureOfScience

Four panellists sit on stage with microphones under the title “The Future of Cancer Research.” Left to right: Jose Adrover, Momo Bentires-Alj, Sarah-Maria Fendt, and our chair, Erik Sahai.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🫘 Session theme: Cancer and Systemic Physiology Research talks explored inherited kidney cancer, breast cancer metastasis, liver cancer, and liver mets from colorectal cancer. With speakers from Cologne, Leuven and here at Crick. A rich mix of models and techniques. #CrickCancerConf #Metabolism

Sarah-Maria Fendt stands at a podium in front of a slide showing acknowledgements and collaborators, including logos for VIB, KU Leuven, Horizon Europe, and World Cancer Research Fund. The slide marks the end of a talk on cancer metabolism.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🔧 CancerTools.org is building a global collaborative to share cancer research reagents: antibodies, cell lines, organoids and chemicals. No fees for researchers, and revenue goes back to the inventing host institution. #CancerResearch #OpenScience #CancerTools #CrickCancerConf #ResearchImpact

Fatima Aziz (@cancertools.org) stands at a podium delivering a talk on CancerTools.org. The slide reads “Increase your impact” and outlines how researchers can deposit tools to drive innovation, join a global collaborative, and access unique cancer research reagents.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 05/10/2025

🎙️ Midway through Day 1 at the 5th Crick International Cancer Conference - fantastic to be back at the Crick. Talks packed with fresh insights (much of it unpublished, so no spoilers!), and great to see such a strong international turnout. #CrickCancerConf www.crick.ac.uk/whats-on/5th...

crick.ac.uk

5th Crick International Cancer Conference

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 11/09/2025

It’s a 10-minute slot after Natasha Karp and Matt Leach - no pressure! Hoping to spark a ripple effect in how we think about design, rigour, and inclusion in science. #ResearchFunding #EDIinResearch #NC3Rs

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 11/09/2025

Finalising slides for next week’s NC3Rs webinar on sex-inclusive research. I’ll be sharing a funder’s perspective on the SIRF tool - and how we’re moving from policy to practice. 🔗 nc3rs.org.uk/events/tackl... #SexInclusiveResearch #3Rs #SIRF

Stylised icons on a teal background represent the building blocks of inclusive science - DNA strands, data charts, and balance scales symbolise the integration of male and female samples in research. The image evokes thoughtful design, equity, and the pursuit of relevance in experimental models.

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

NC3Rs @nc3rs.bsky.social · 09/09/2025

Teach others how to use the EDA to design rigorous in vivo experiments that use the minimum number of animals: nc3rs.org.uk/events/ukrn-... ⏳ Registration closing soon: Wednesday 17 September 🤝Delivered by @drejpearl.bsky.social and @ukrepro.bsky.social 📅 Thursday 13 November, 10.00 – 16.00 (GMT)

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Cancer Research UK @cancerresearchuk.org · 01/09/2025

September is Childhood Cancer Awareness Month 💛 Cancer is different in children and young people, so it needs a different and dedicated approach. We partner with other charities, funders and people affected by these cancers across the UK and around the world – learn more: cruk.ink/3JEskaM

Gold graphic with text which reads, “Childhood Cancer Awareness Month”

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Cancer Research UK @cancerresearchuk.org · 18/08/2025

@peterstefanovic.bsky.social, @carolvorders.bsky.social and 24 other public figures have put their names to our open letter to @rthonwesstreeting.bsky.social, urging him to make the upcoming National Cancer Plan for England a #TurningPointForCancer. Sign the open letter here: cruk.ink/4fHgR6c

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Nature @nature.com · 31/05/2025

Manufacturing CAR T cells in the laboratory is expensive and time-consuming. An in vivo approach could get this powerful therapy to more people go.nature.com/45w5A5w

go.nature.com

Cancer-fighting immune cells could soon be engineered inside our bodies

Nature - Manufacturing CAR T cells in the laboratory is expensive and time-consuming. An in vivo approach could get the powerful therapy to more people.

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

IGMM-Montpellier @igmm-montpel.bsky.social · 28/05/2025

📣 We are recruiting new group leaders in Innovative Biology! RNA biology Epigenetic regulation Cell cycle regulation Cancer, immunology Virology Application and information ⬇️ application.igmm.cnrs.fr @cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

CRUK Convergence Science Centre @crukconvergence.bsky.social · 02/06/2025

Join us for our next #ConvergingOnCancer seminar where we'll explore these topics with: ➡️Prof @doryenbubeck.bsky.social‬ (@imperialsci.bsky.social‬) ➡️Dr @claudioalfieri.bsky.social‬ (@icr.ac.uk‬ ) 📅 Thursday 5th June, 3-4pm 🖱️ For more information and how to register: bit.ly/3Z80SqS

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Journal of Cell Science @jcellsci.bsky.social · 05/06/2025

The application deadline for our next round of 🔬Training Grants is this Friday 6 June. www.biologists.com/grants/jcs-f...

biologists.com

JCS-FocalPlane Training Grants

About JCS-FocalPlane Training Grants JCS-FocalPlane Training Grants are aimed at early-career researchers, working in an area covered by JCS, who would like to attend a microscopy training course. The...

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

Lastly, it was suggested that U.K.-based cancer researchers a may wish to join the British Association for Cancer Research (BACR), who exist to bring the community together and provide events to connect researchers. #BACR2025

Kevin Ryan shared the benefits of BACR membership including travel bursaries, awards, reduced event fees and membership of EACR (the European Association for Cancer Research).

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

The Molecular Oncology journal is a non-profit open access journal (IF5.0). Charges paid by authors all go to fund future FEBs Fellowships and events. #OpenAccessJournal #MolecularOncology

This journal was advertised by Kevin Ryan (CRUK Scotland Institute but also journal Editor) and is published by FEBS Press.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

The British Association for Cancer Research also have a conference in the autumn, in Southampton themed on Cancer Immunology and Therapeutics. #CancerConference #Immunology

Mark Cragg (pictured at lectern), and later also Kevin Ryan (not pictured) invited those in or interested in the Cancer Immunology field to Southampton in September for the next BACR event.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

Opportunities at Barts Cancer Institute for new Assistant/Professors in Tunour Microenvironment… #NewPIs

Kebs Hodivala-Dilke advertised (new) Group Leader opportunities at her institution, Queen Mary University of London (QMUL), at the Barts Cancer Institute.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

Now on the train home after a wonderful few days in Edinburgh, but one last post about #BACR2025. Many of the talks ended with a slide highlighting opportunities so here’s a thread of those I managed to photograph! #NewPIopportunuties #CancerConferences #ResearchJournals and #ProfessionalSocieties

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

Onto the last Keynote talk at BACR in Edinburgh. It’s René Bernards from NKI. What a great 3 days it’s been! Thank you to the organisers and congratulations to all the prize winners. #BACR2025

René Bernards is introducing his talk, “Behave or die, a novel approach to cancer therapy”.

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

VickySanzMoreno @vickysanzmoreno.bsky.social · 03/06/2025

Very proud of former PhD student Yaiza Jung who has received the #BACR Chris Marshall Prize for Cell Signalling 😍! it was such a pleasure to co-supervise her PhD with @jezcarlton.bsky.social 😀

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 04/06/2025

After a fun and chaotic Cèilidh last evening we’re back in lectures this morning as the 65th anniversary BACR meeting continues in Edinburgh. Mathew Garnett from the Sanger is first up. #BACR2025

Mathew Garnett stands behind the wooden lectern in a blue shirt. Above him the screen introduces his talk on “Mapping Cancer Dependencies to Guide Precision Cancer Medicine”.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 03/06/2025

Back for the afternoon session at BACR. First up it’s Mark Cragg from Southampton talking about antibodies as drugs against cancer. #BACR2025

Mark Cragg in a checked short-sleeved shirt is now behind the lectern. Behind and above him is a huge crystal structure of an antibody, and a graphic celebrating the recent FDA approval of the 100th antibody-based drug.

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 03/06/2025

The LMB is committed to being open & honest about why & how we use animals in our research. Our Biological Services Group provide excellent care to our colonies of rodents – our fantastic animal technicians explain why they work with mice in this video: youtu.be/V7CHmPGjvSo #BOARD25 @eara.eu

youtu.be

Why I Work with Mice in Research - An Animal Technician's Point of View

YouTube video by MRC Laboratory of Molecular Biology

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Reposted by Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺

Sebastian Greenhough @sebgreenhough.bsky.social · 02/06/2025

Day 1 of the British Association for Cancer Research 65th Anniversary Meeting. Some good stuff on DNA repair, nonsense-mediated decay, epigenetics, dormancy, metabolism and lots more. Nice venue too - The Royal College of Physicians of Edinburgh. Back again tomorrow! @thebacr.bsky.social #BACR2025

A busy conference auditorium awaits the first speaker.

The ornate ceiling of the Great Hall featuring gold pillars, statues, elaborate plasterwork and a chandelier.

The Progress Pride flag flies outside the main entrance.

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Jacqui Marshall PhD CSci 🧪🧫🧬🧑‍🔬🧑‍💻📊🌳🏞️🧗🥎🇪🇺 @jjmarshall.bsky.social · 03/06/2025

It’s Day 2 of the BACR meeting in Edinburgh. First up Derek Mann from Newcastle talking about liver cancer. #BACR2025

Derek Mann in a white shirt stands at the lecturn in front of a huge screen showing a cartoon of a liver indicating key cell types involved in fatty liver disease.

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