iiinova — where your digital self keeps evolving

Reposted by Jeff Maltas

Scott Juntti @scottjuntti.bsky.social · 27/09/2026

This matters because visual input must be transformed into coordinated motor output, moment by moment. Comparing cichlids and zebrafish reveals that similar behavioral goals can be achieved through different movement strategies—linking evolutionary diversity to the organization of behavior.

1105

Jeff Maltas @jeffmaltas.bsky.social · 27/09/2026

Only 1 month into the job and already has a NYT featured about her research? And I hear she's recruiting graduate students this cycle?!

130

Reposted by Jeff Maltas

John McEnany @johndmcenany.bsky.social · 05/09/2026

Just preprinted my work on rapid evolution in fluctuating environments! When many linked mutations with different environmental tradeoffs compete, I found that mutations with stronger tradeoffs systematically outcompete beneficial “generalist” mutations. Read more here: doi.org/10.64898/202...

doi.org

23010

Jeff Maltas @jeffmaltas.bsky.social · 02/09/2026

This is my understanding of the most fundamental difference. Fisher's model is single-peaked, and Simpson's is multi-peaked, both by design.

100

Reposted by Jeff Maltas

Alvaro Sanchez @asanchezlab.bsky.social · 21/08/2026

New preprint from the lab: The Latent Simplicity of Microbial Ecological Interactions www.biorxiv.org/content/10.6... We're excited about this one. We find that high-order microbial interactions often obey simple linear laws, making microbial communities far more predictable than one might expect.

12710

Reposted by Jeff Maltas

Paper Skygest Team @paper-feed.bsky.social · 19/08/2025

**Please repost** If you're enjoying Paper Skygest -- our personalized feed of academic content on Bluesky -- we'd appreciate you reposting this! We’ve found that the most effective way for us to reach new users and communities is through users sharing it with their network

2114143

Jeff Maltas @jeffmaltas.bsky.social · 03/08/2026

I think the mathematics community is one of the academic communities that least migrated to bluesky?

000

Reposted by Jeff Maltas

Juan Angueyra @juanonyme.bsky.social · 21/07/2026

Preprint for the first manuscript of the Angueyra Lab is out! We delve deep into cell-fate decisions during photoreceptor development and discover that the 𝘵𝘣𝘹2 paralogues play multiple roles to control the fate of the five photoreceptor subtypes in zebrafish.

22411

Reposted by Jeff Maltas

Michael D. Green, PhD @michaeldgreen.phd · 28/05/2026

President of MIT not mincing words today in @statnews.com www.statnews.com/2026/05/27/s...

So let me say it as clearly as I can: Without basic scientific research, supported by the kind of farsighted public investment that allows large-scale, undirected, curiosity-driven inquiry, the scientific pipeline will run dry.
In daily life, people may not feel the effects right away, or even in 10 years. But we will feel it. And when someone we love needs therapies that could have emerged but didn't or when other countries now
investing in science can launch new science-based industries or run their societies on vast resources of fusion energy or reap the benefits of quantum computing power or advanced medical breakthroughs, America will wish it sustained its leadership in scientific research here and now.
Sally Kornbluth is the president of MIT.

447188346434

Jeff Maltas @jeffmaltas.bsky.social · 09/04/2026

So sorry, Rich. Devin was such a sweet guy and kind soul. My condolences.

010

Jeff Maltas @jeffmaltas.bsky.social · 07/04/2026

Happy to contribute if you want to go down that path! There's a couple of interesting regimes with similar quick extensions. Happy to jot a few things down.

110

Jeff Maltas @jeffmaltas.bsky.social · 07/04/2026

This is cool Will! Thinking out loud... if an organism reproduces by fragmentation, the cost of soma remain quite high? Say an organism splits into k fragments of size N/k. Then the scaling rule becomes ln(p_g)/ln(k), not ln(p_g)/ln(N). Should be testable in the same way?

220

Reposted by Jeff Maltas

Guim Aguadé-Gorgorió @guimaguade.bsky.social · 17/03/2026

Excited to announce Eco-Onco Exchange — a virtual seminar series bridging mathematical ecology and oncology. Each session pairs two speakers from each field around a shared theme, followed by joint discussion. First three sessions coming soon! Register here docs.google.com/forms/d/e/1F...

12110

Reposted by Jeff Maltas

Julia Van Etten @couchmicroscopy.bsky.social · 14/03/2026

I have a new review out in TiG titled, “The ecology of horizontal gene transfer”! I’ve been thinking about these ideas for years and this field is growing so fast it’s becoming impossible to review it. I hope this paper sparks discussion on different ways we can look at DNA transfer!

sciencedirect.com

The ecology of horizontal gene transfer

Horizontal gene transfer (HGT) generates genetic variation in populations across all domains of life; however, most studies focus on individual transf…

03518

Reposted by Jeff Maltas

Trevor Graham @trevorgraham.bsky.social · 13/03/2026

New preprint: evolution of cross-resistance between two cancer drugs inferred from lineage barcoding data from single drug exposures. Removes need for complex combinatorial exposure experiments. Another tour de force from brilliant Freddie Whiting @icr.ac.uk www.biorxiv.org/content/10.6...

biorxiv.org

0144

Jeff Maltas @jeffmaltas.bsky.social · 06/03/2026

I would be very happy to chat with prospective postdocs that have interest in quantitative biology as it applies to understanding the fundamental evolutionary and ecological processes that drive the acquisition and maintenance of resistance in microbes and cancer.

010

Jeff Maltas @jeffmaltas.bsky.social · 06/03/2026

Applicants will have two mentors and are encouraged to reach out in advance. The Department is filled with wonderful people doing great science. Department: biology.umd.edu/people Core QBI faculty: Bruns, Butts, Cummings, Fagan, Johnson, Karatayev, Maltas, Simon, Sukharev, Weitz

biology.umd.edu

People

110

Jeff Maltas @jeffmaltas.bsky.social · 06/03/2026

My Department at the University of Maryland is offering three postdoctoral fellowships in quantitative biology as part of a new Quantitative Biology Initiative! Best consideration date: 3/14 Job Ad: umd.wd1.myworkdayjobs.com/en-US/UMCP/j...

umd.wd1.myworkdayjobs.com

121

Reposted by Jeff Maltas

Katie Mack @astrokatie.com · 24/02/2026

I'm constantly trying (/failing) to get this point across. If you're a trained expert in a field, then it may be worthwhile to question the scientific consensus of your peers. If you're not, the scientific consensus is absolutely the best you can do and it's arbitrary foolishness to disregard it.

523727842

Jeff Maltas @jeffmaltas.bsky.social · 20/01/2026

Record and upload to youtube :)

140

Jeff Maltas @jeffmaltas.bsky.social · 18/12/2025

Really cool work from Kimberly Kline and others! In the too little talked about E faecalis!

020

Jeff Maltas @jeffmaltas.bsky.social · 08/12/2025

Always wanted to see Rinzel as the 2nd line center.

100

Reposted by Jeff Maltas

The Tennessee Holler @thetnholler.bsky.social · 28/09/2025

79. American citizen.

19442367611582

Reposted by Jeff Maltas

Vaughn Cooper @vscooper.micropopbio.org · 23/09/2025

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine. 1) MMG (my dept): fundamental research in med micro 2) Peds ID / I4Kids institute 3) Center for Vaccine Research 🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...

linkedin.com

Faculty Professor Associate - Full-Time | Vaughn Cooper

We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...

190125

Reposted by Jeff Maltas

MathOnco @mathonco.bsky.social · 21/09/2025

Interested in doing a PhD in #MatOnco next year? Our department at @moffittnews.bsky.social is a great place to do research and we offer fully-paid tuition and fees. Apply before the deadline 12/1 at Moffitt.org/CancerPhD

024

Jeff Maltas @jeffmaltas.bsky.social · 19/08/2025

I found this to be just as evident with reading. I spent some time having AI summarize new papers. I found it did a decent job! Only a month later I had retained none of the information of those papers. I had spent no time milling with the ideas, figures, or experiments. Useless.

030

Reposted by Jeff Maltas

Daniel Cooney @danielcooney1.bsky.social · 18/07/2025

I am really happy to share that there will be a @nitmb.bsky.social workshop next year on mathematical and biological features of evolutionary game theory. It was really fun to co-organize this workshop with Olivia Chu, Alex McAvoy, and @jplotkin.bsky.social. www.nitmb.org/evolutionary...

nitmb.org

Evolutionary Games: Mathematical Theory and Biological Insights

24219

Reposted by Jeff Maltas

Will Ratcliff @wcratcliff.bsky.social · 24/06/2025

1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬 www.science.org/doi/full/10....

14357145

Jeff Maltas @jeffmaltas.bsky.social · 19/06/2025

When the filter is removed (change to non-selective environment), a higher dimensionality of pleiotropic effects becomes apparent. The study finds no evidence for this hypothesis, and instead supports the "pleiotropic shift" model.

100

Jeff Maltas @jeffmaltas.bsky.social · 19/06/2025

My understanding is this is correct. In their pleiotropic expansion model, the mutations all have a broad inherent pleiotropy, but the selective environment acts as a filter, allowing only a low-dimensional subset to be relevant for fitness in that environment.

100

Jeff Maltas @jeffmaltas.bsky.social · 29/05/2025

The idea would be a sphere is perfectly captured by the l=0 harmonic, while less spherical shapes will required increasingly higher order harmonics to accurately describe. Maybe more resolution/information than surface area vs volume, but less intuitive to interpret for readers.

120

Jeff Maltas @jeffmaltas.bsky.social · 29/05/2025

This might be something that decomposing the shape into its spherical harmonics could do quite well.... It's kind of like how a Fourier transform breaks a complex signal down into sines and cosines, but it's breaking a 3D shape down into orthogonal shapes on a sphere.

130

Jeff Maltas @jeffmaltas.bsky.social · 22/02/2025

Ba6, c4, Rf3, b3, Rf8 Black looks really good but after c4 gumming up the nice mate, I'd find a way to lose this :)

040

Reposted by Jeff Maltas

Vaughn Cooper @vscooper.micropopbio.org · 21/01/2025

I'm incredibly honored by this opportunity to serve as President-Elect of @asm.org starting this summer. Looking forward to working with the Board, ASM leadership ,and staff to help advance the microbial sciences. I'm also glad to share my Vision statement, please join us! asm.org/Press-Releas...

4938570

Reposted by Jeff Maltas

Andrew Steele @statto.bsky.social · 16/01/2025

WhatsApp is owned by Meta, the company behind Facebook, Instagram and, most recently, firing all their content moderators for political expediency. So this is a reminder to download Signal, a free messenger run by a nonprofit which is like WhatsApp but more secure and private: signal.org

signal.org

Signal Messenger: Speak Freely

Say "hello" to a different messaging experience. An unexpected focus on privacy, combined with all of the features you expect.

0146

Jeff Maltas @jeffmaltas.bsky.social · 14/01/2025

Really great new work from the always interesting @csabapallab.bsky.social lab!

030

Jeff Maltas @jeffmaltas.bsky.social · 10/01/2025

For what it's worth, chrome and firefox both have extensions to high google AI, which is typically what I have going on.

020

Jeff Maltas @jeffmaltas.bsky.social · 10/01/2025

Google AI is horrible. You alter the search even a little bit and the answer is dramatically different. I wish duckduckgo was a slightly better search engine.

Google search AI results for "highest dn/ds evolution measured" showing improved results.

140

Jeff Maltas @jeffmaltas.bsky.social · 09/01/2025

As a final note, I just want to drop a shout out to Anh (not on bsky) who helped make this possible after I graduated. She did some important experiments during the revision process and she's a truly spectacular scientist.

000

Jeff Maltas @jeffmaltas.bsky.social · 09/01/2025

As a result, collateral profiles are highly dynamic/variable through evolutionary time and we need a stochastic control model to optimize treatment. To do with we adapted our 2019 Markov Decision Process model to include temporally varying state profiles!

110

Jeff Maltas @jeffmaltas.bsky.social · 09/01/2025

We see that adaptation to antibiotics results in near uniform collateral resistance, further adaptation results in both collateral sensitivity and resistance. This is very similar to recent work from @grantkinsler.bsky.social @petrovadmitri.bsky.social in their yeast two-step paper (also in PLOS B)!

121

Jeff Maltas @jeffmaltas.bsky.social · 09/01/2025

Very excited to have this paper officially out. This one is pretty special... Unfortunately, @kevinwoodum.bsky.social passed away when this paper was in its final stages. He was my biggest supporter, and I miss him deeply as a mentor and friend.

22714