Cases in the Northern Hemisphere are cropping up weeks early, and they are dominated by a virus with a concerning mutation.

Serological data provide important insights into SARS-CoV-2 transmission and immunity, particularly in regions with limited routine surveillance such as sub-Saharan Africa. However, antibody waning an...

Non-pharmaceutical interventions for COVID-19 also reduced circulation of endemic viruses which may have led to immune waning. Here, the authors use multiplex serology data from King County, Washingto...

Abstract. Viral kinetics provide crucial insights into the biology and epidemiology of infections, with direct implications for basic science, therapeutics

Background: Serological data provide important insights into SARS-CoV-2 transmission and immunity, particularly in regions with limited routine surveillance suc

Key findings England is currently experiencing a high growth rate of infections caused by the influenza A/H3N2 K clade. Antigenic change from the previously dominant clade, a rapid selective sweep evi...

Key findings England is currently experiencing a high growth rate of infections caused by the influenza A/H3N2 K clade. Antigenic change from the previously dominant clade, a rapid selective sweep evi...

Seasonal influenza (‘the flu’) is an acute respiratory infection caused by influenza viruses that circulate globally and year-round. It can cause illness ranging from mild to severe, sometimes resulti...

Author summary Understanding how viruses reproduce within an infected host is crucial for predicting disease progression and evaluating treatments. One way to study this is by using mathematical model...

The influenza virus continues to pose a significant threat to public health throughout the world. Current avian influenza outbreaks in humans have heightened the need for improved surveillance and planning. Despite recent advances in the development ...

National influenza (flu) and COVID-19 report, monitoring COVID-19 activity, seasonal flu and other seasonal respiratory illnesses.

Influenza A(H3N2) subclade K (J.2.4.1) has dominated the 2025/26 season start in England. Post-infection ferret antisera raised against northern hemisphere 2025/26 vaccine strains showed reduced reactivity to subclade K viruses in England, aligning with World Health Organization reports. Nevertheless, early post-vaccination, vaccine effectiveness against influenza-related emergency department attendances and hospital admissions remained within typical ranges, at 72–75% in children and adolescents (< 18 years) and 32–39% in adults. Hence, vaccination remains effective against clinical disease caused by influenza A(H3N2) viruses.

YouTube video by World Health Organization Regional Office for the Western Pacific

Key findings England is currently experiencing a high growth rate of infections caused by the influenza A/H3N2 K clade. Antigenic change from the previously dominant clade, a rapid selective sweep evi...

Population-level distributions of SARS-CoV-2 viral load can correlate with epidemic trends. Here, the authors use viral loads to nowcast epidemic growth rates over two-week periods and investigate how...

The `serojump` package provides tools for fitting serological models to antibody kinetics data using reversible-jump Markov Chain Monte Carlo (RJ-MCMC). It enables researchers to model the dynamics of...