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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 08/09/2026

Tune in to a new on-demand deep dive from Labroots and Phase Genomics CEO @ivanliachko.bsky.social on how Hi-C metagenomics connects fragmented DNA and reveals relationships among phages, plasmids, and other MGEs in the microbiome. You’ll find Ivan’s talk here: www.labroots.com/ms/webinar/l...

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Ivan Liachko @ivanliachko.bsky.social · 21/08/2026

Best quotable of #ISME20 a la Phil Hugenholtz: Q: "Phil, do you have FOMO?" A: "No, I have the fear of being included" @xrefugee13.bsky.social @isme-microbes.bsky.social #microbiome

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 18/08/2026

Look for Phase Genomics CEO @ivanliachko.bsky.social at #ISME20 this week. He’ll join a special session exploring the translation of microbiome science into commercial applications. You’ll find the session, MS25: Microbiome-Based Products, in room 516 on 8/21 starting at 10:30 am local time.

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Ivan Liachko @ivanliachko.bsky.social · 08/04/2026

Chatting with Jeff about his recent paper on the oat pangenome 🌱🧬. #plants #genome

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 19/02/2026

New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration. More from Todd Michael, PhD & team at @salkinstitute.bsky.social l 📄 www.nature.com/articles/s41...

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 29/01/2026

Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them. A few of our favorite moments👇

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 03/02/2026

"A year and a half ago, we couldn't have resolved this hybrid genome." New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael, PhD breaks down how:

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Ivan Liachko @ivanliachko.bsky.social · 25/11/2025

Time for our End of Year sale! If you need an excuse to talk to me about science, this is one way to get there (but also, I'll do it for free 🧬 ❤️ )

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 06/11/2025

🌿 New in @NaturePlants! Researchers used Phase Genomics’ Hi-C to build a haplotype-resolved chromosome-scale #genome of a hybrid eelgrass (Zostera marina × Z. pacifica), revealing genomic clues to low-light tolerance that could boost coastal restoration. www.nature.com/articles/s41...

nature.com

Hybridization and low-light adaptability in California eelgrass (Zostera spp.) - Nature Plants

Seagrass genomes of the deep-water Zostera pacifica and shallow-water Z. marina from the Eastern Pacific Ocean provide evidence for low-light adaptation exemplified in the wild hybrid Z. marina × paci...

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 28/10/2025

Phase Genomics’ Hi-C tech helped undergrads assemble the “best duckweed genome yet,” giving them hands-on research experience, boosting PhD prospects, and advancing plant biology. Full story from Alex Harkess at HudsonAlpha on YouTube: na2.hubs.ly/H01P7mG0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 22/10/2025

Happy #WorldPhageDay. Tiny, abundant, and anything but boring, phages shape microbial communities, move genes around, and can tip the balance in all kinds of ecosystems. The catch: to know a #phage only you must know its host. ProxiMeta Hi-C technology gives us that link.

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 21/10/2025

🌳 New chromosome-level Ulmus minor (field elm) genome unlocks clues to Dutch elm disease resistance. Using long reads and Hi-C, the team built this 2.1Gb genome and mapped clusters of resistance genes conserved across elm species to aid restoration. na2.hubs.ly/H01HQ2Q0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 29/09/2025

In this great new paper, the authors use metagenomic Hi-C to show that #phage with broad host range are fairly common, contrary to the prevailing view on their biology. Cutting edge methods like Hi-C are shedding light on our blind spots in the microbial world.

nature.com

Phages with a broad host range are common across ecosystems - Nature Microbiology

Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 11/09/2025

Join us at the Microbiome Innovation One Health Conference in Oxford on Sept 15! @ivanliachko.bsky.social will present how ProxiMeta™ maps microbes, viruses, plasmids & resistance genes, bringing clarity to complexity across human, animal and environmental health.

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 04/09/2025

🧬 Important Slug News! Researchers assembled a chromosome-scale #genome for Deroceras laeve using Proximo Hi-C and @pacbio.bsky.social - making it a useful model for study of #genomics, #evolution, and slimyness... Congrats to Alfredo Varela-Echavarría & team! 🔗 academic.oup.com/g3journal/ad...

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 21/08/2025

A fungus among us: Proximo Hi‑C + @pacbio.bsky.social HiFi produced telomere‑to‑telomere genomes for VCG‑01111/01112, uncovering 4 accessory chromosomes, >3.6 My divergence, SIX6 and novel effectors—pinpointing drivers of high virulence. www.mdpi.com/2309-608X/11...

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Reposted by Ivan Liachko

Karen James @kejames.bsky.social · 17/08/2025

She doesn’t need a hero, she is the hero we need. 🤩

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 06/08/2025

Structural variants often go undetected by traditional cytogenetics. A new review in Genes shows how Genomic Proximity Mapping™ (GPM) detects complex SVs right from FFPE. Read more Dr. Patrick Gonzales at the University of Kansas Medical Center: www.mdpi.com/2073-4425/16...

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 04/08/2025

When sample quality is low, insight usually is too. Not with Genomic Proximity Mapping™ (GPM). Phase Genomics’ GPM works on #FFPE and mosaic samples. It’s just one assay, no metaphase prep, and no tradeoff in resolution. A new preprint shows how: www.medrxiv.org/content/10.1...

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 01/08/2025

Comprehensive cytogenetics from any sample type—including #FFPE—in just one assay: CytoTerra® delivers genome-wide SV detection with no culture, no HMW DNA, and results in as little as 5 days. Stop by booth 23 & check out our presentations to see it in action at #CGC2025.

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 25/07/2025

🌸 Chromosome-scale genome of Petunia hybrida assembled with Proximo Hi-C, PacBio HiFi, Illumina & Bionano. 7 pseudochromosomes, 99.8% BUSCO with Hi-C being key for resolving repeats. A powerful resource for Solanaceae genetics & breeding. #genome #HiC 📄 hubs.la/Q03ypPmb0

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Ivan Liachko @ivanliachko.bsky.social · 23/07/2025

By popular demand by you, #genomics people - this buffer is super useful for Hi-C and we'll give you some if you ask for it, no strings attached.

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 22/07/2025

🌱🧬Researchers released haplotype-resolved, chromosome-level genomes of Eupatorium splendens - a plant known for medicinal properties and ability to thrive in contaminated soils. A powerful resource for studying stress adaptation & secondary metabolism. www.nature.com/articles/s41...

nature.com

Haplotype-resolved chromosome-level genome sequence of Elsholtzia splendens (Nakai ex F.Maek.) - Scientific Data

Scientific Data - Haplotype-resolved chromosome-level genome sequence of Elsholtzia splendens (Nakai ex F.Maek.)

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 15/07/2025

🍓 Meet ‘Yuexin’ - a next-gen #strawberry with smoother texture, better shelf life, and sweeter aroma. Scientists have released its fully phased #genome, revealing the genetic secrets behind these tasty traits. Proximo #HiC + @pacbio.bsky.social for the win! 🧬 🔗 hubs.la/Q03tZvZD0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 09/07/2025

“It’s not a brute force technology. It’s a clever technology.” — Jon Chee, CEO @ Excedr In the finale of The Biotech Startups Podcast, Jon and @ivanliachko.bsky.social unpack how smart science powers Phase Genomics' impact in cancer research, metagenomics & more👇 youtu.be/fqL6ZvS2sNQ?...

youtu.be

Growth Without Venture Capital: The Bootstrapped Biotech Playbook | Ivan Liachko (Part 4/4)

YouTube video by The Biotech Startups Podcast | Excedr

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 08/07/2025

New💩🚰👨‍🔬 study in #EnvMicrobiology uses shotgun & Hi-C metagenomics to reveal rapid shifts in antibiotic resistance genes and their microbial hosts, highlighting the dynamic nature of resistomes. #AMR #Metagenomics 🔗https://hubs.la/Q03tZ1Jf0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 03/07/2025

TBT: 🧬 Throwing it back to a cool study from Aug 2021! Using proximity ligation, this paper explores the two-compartment genome of R. irregularis, a model arbuscular mycorrhizal symbiont, using Proximo #HiC and @nanoporetech.com sequencing. @Blunt_Microbe 🔗 Full study: hubs.la/Q03tZ6Ch0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 02/07/2025

“If we don’t commercialize this, it’s going to be a crime against science.” - @ivanliachko.bsky.social, Founder and CEO Hear how a postdoc aha moment became a platform accelerating #microbiome research, tackling #AMR & more on the Biotech Startups Podcast: www.youtube.com/watch?v=U2UG...

youtube.com

How 3D Genome Mapping is Changing Everything We Know About DNA | Ivan Liachko (Part 3/4)

YouTube video by The Biotech Startups Podcast | Excedr

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 01/07/2025

Unleashing the wild side of lupins! 🌕🐺🍃 Researchers built #genomes of rough-seeded lupins - L. cosentinii & L. digitatus - revealing unique #gene expansions tied to stress resilience and seed traits. A howling good resource for legume breeding! #HiC 🔗 hubs.la/Q03v1F2c0

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 27/06/2025

Can’t see the full picture with karyotyping or microarrays? New research in @Genes_MDPI shows how Genomic Proximity Mapping (GPM) detects structural variants other tools miss - translocations, insertions & CN-LOH - even from FFPE! hubs.la/Q03v2s2N0 #Cancer #Cytogenetics

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 20/06/2025

Phase Genomics is making Hi-C metagenomics simpler than ever with the new ProxiMeta™ Starter and Elite Bundles. These ready-to-run solutions combine sequencing, no-code bioinformatics & expert support into streamlined packages. #microbiome #phage More in @BioSpace: www.biospace.com/press-releas...

biospace.com

Phase Genomics Launches ProxiMeta™ Starter and Elite Bundles to Expand Access to Genome-Resolved Metagenomics

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Ivan Liachko @ivanliachko.bsky.social · 19/06/2025

Very excited to be at American Society for Microbiology #ASMicrobe meeting. I’m here with a large suitcase of, what could it be? Science swag and also just science. Come talk to us about transforming the future of #metagenomics and #phage research. @phasegenomics.bsky.social (booth 1109)

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 19/06/2025

Just launched at #ASMicrobe 2025: the new ready-to-use ProxiMeta™ Starter and Elite bundles for Hi-C metagenomics. Visit booth #1109 to chat w/ the team about how the new bundles can accelerate your research, or discover more online & book a call here: info.phasegenomics.com/proximeta-bu...

info.phasegenomics.com

Meet ProxiMeta

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 19/05/2025

ICYMI: A jam-packed spring edition of Phasebook, available in your inbox and on the web. You’ll find all the latest on our Hi-C tech and updates from the Phase Genomics team here: info.phasegenomics.com/phasebook

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 14/05/2025

Catch Phase Genomics CEO @ivanliachko.bsky.social at NIAMRRE 2025 for an insightful panel discussion on #AMR in today’s shifting landscape on Thurs, May 15. Find the full details and register here: exchange.niamrre.org/2025niamrrea...

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Ivan Liachko @ivanliachko.bsky.social · 05/05/2025

Another impressive paper, the authors used Proximo Hi-C data to build a allohexaploid wheatgrass genome.

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Ivan Liachko @ivanliachko.bsky.social · 01/05/2025

I hear the first author is defending tomorrow 🐦, so read this paper. Also, this is what happens when leadership learns how to use Canva...

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Ivan Liachko @ivanliachko.bsky.social · 29/04/2025

Cool paper on #duckweed #genomes, now with free gratuitous frog 🐸.

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Ivan Liachko @ivanliachko.bsky.social · 22/04/2025

Really neat paper out, using measurements of 3D genome folding (with our Proximo Hi-C tech, wink wink) to pinpoint the CA2 gene as a potential target to reverse drug resistance in #breastcancer.

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Ivan Liachko @ivanliachko.bsky.social · 17/04/2025

Very cool recent preprint from @chicascientifica.bsky.social and team. #phages in bee poop, what's not to like? #microbiome #bees

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 15/04/2025

2 weeks from today: Catch Phase Genomics’ @IvanLiachko and Steve Eacker at #AACR2025 in Chicago, April 25–30. We’ll present two posters on Genomic Proximity Mapping™ (GPM) for the genome-wide detection of chromosomal abnormalities in HNSCC & sarcoma. Find the full details:

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Ivan Liachko @ivanliachko.bsky.social · 09/04/2025

We made a new tool to help people process deep #metagenomics data. If you’re scared of R and prefer to clicky click and draggy drop things instead, while making beautiful figures, check this out. Oh and it’s free, are we crazy?!? #microbiome #phage #AMR

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 18/03/2025

The best things come in 2s—like our purpose-built, user-friendly Proximo™ Hi-C Plant Kit two-packs. Purchase a Proximo Hi-C Plant two-pack by April 30 & we’ll send you #PGShield preservative for long-term sample storage at *without* refrigeration. 🛒 bit.ly/4iLCuCy

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 26/02/2025

Tune in to the Talk is Biotech podcast to hear Phase Genomics CEO @ivanliachko.bsky.social share how Hi-C unlocks new DNA discoveries: “It’s a sequence of letters, but it makes shapes, colors—it makes a strawberry look like a strawberry.” Thanks to pod host Guru Singh: bit.ly/4ijpyUy

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Reposted by Ivan Liachko

Phase Genomics @phasegenomics.bsky.social · 11/02/2025

Today on the International Day of Women & Girls in Science—and every day—we honor the women who drive discovery forward. From the double helix to WiFi, we celebrate their discoveries that define modern life. Because women shape every second of science, every day of the year.

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