Join us at the Keystone Symposia on Vaccinology: A New Era in Immune-Driven Vaccine Design, May 2026, in Killarney, with field leaders!

Join us at the Keystone Symposia on Vaccinology: A New Era in Immune-Driven Vaccine Design, May 2026, in Killarney, with field leaders!

This study examines the emerging use of agentic artificial intelligence (AI) in biomedical research, highlighting the challenges and opportunities that may inform the design of agentic AI systems suit...

This study examines the emerging use of agentic artificial intelligence (AI) in biomedical research, highlighting the challenges and opportunities that may inform the design of agentic AI systems suit...

Engineered cellular immunotherapy shows great potential for treating autoimmune diseases. Payne and colleagues review emerging clinical data of the most recently developed technologies.

Hughes and colleagues present a developmentally inspired tissue engineering strategy to overcome barriers in kidney tissue generation, enhancing prospects for renal replacement therapies.

RNA’s dynamic nature and complex physiochemical properties make it difficult to structurally resolve. This Perspectives examines how integrating experimental and computational approaches to structure ...

Nature Biotechnology - Genome editing technology is evolving fast, and many labs worldwide are generating crop plants with improved traits. If transgenes were used to generate the edits, foreign...

Recent developments in B cell engineering expand our ability to study human disease and drive progress toward new B cell therapies, balancing challenges in clinical implementation with emerging opport...

Gene regulatory networks are crucial for understanding complex gene regulation in plants and could advance crop improvement for more sustainable and climate-resilient agricultural practices.

A classification of hybrid engineered biological systems is presented to support researchers in making design choices that expand their use.

Optimized TALE base editors are used to generate a rat model of mitochondrial disease and then revert the disease mutation in the next generation.

23andMe’s bankruptcy serves as a moment of reflection for the direct-to-consumer (DTC) genomics industry. We analyzed 23andMe financial data and business practices to reveal the factors behind the fal...

Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.

Nature Biotechnology - A call for built-in biosecurity safeguards for generative AI tools

Nature Biotechnology - Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.

The development of therapeutic cancer vaccines has long been a promising yet challenging field of research. While early efforts were impeded by limited efficacy and immune escape, recent advances in i...

Despite major advances in bringing cancer cell therapies to the clinic, their widespread accessibility remains a substantial challenge. High manufacturing costs, lack of funding and varying regulatory...

Synergizing advances in artificial intelligence with mathematical modeling will improve our ability to computationally predict immunotherapy outcomes.

The unique attributes of innate immune cells position them as attractive candidates for cancer immunotherapy, with engineering strategies to enhance their antitumor potential, offering notable therape...

Shares of U.S. drugmakers fell on Monday after reports that the Food and Drug Administration's top vaccine official, Peter Marks, had been forced to resign, the most high-profile exit at the regulator as the Trump administration undertakes an overhaul of federal health agencies.

Our ability to use engineered bacteria for cancer therapy is rapidly expanding. A survey of preclinical, clinical and commercial efforts provides an overview of the state of the field, revealing trend...

Technologies to modulate induced proximity at the cell surface advance the manipulation of diverse biological responses.

Nature Biotechnology - Maglia and colleagues discuss advances in nanopore technology en route to single-molecule protein sequencing

Nature Biotechnology - Challenges for developing broad-based mucosal vaccines for respiratory viruses

Natural and engineered Cas12 and TnpB variants offer diverse applications in genome editing and diagnostics.