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Methods, Evidence Synthesis and Implementation SIG

@iasp-mesisig.bsky.social
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We are a multidisciplinary special interest group @IASP, fostering widespread interest in high-quality methods for pain research. www.iasp-pain.org/membership/specia…

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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 03/06/2026
www.linkedin.com/posts/neil-o...
linkedin.com
Join us for the first International Association for the Study of Pain MESISIG contribution to the Pain Research Forum Journal Club series where I will be discussing the new ISHOOS consensus… | Neil O&...
Join us for the first International Association for the Study of Pain MESISIG contribution to the Pain Research Forum Journal Club series where I will be discussing the new ISHOOS consensus recommenda...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 06/05/2026
WEBINAR ALERT! Our next IASP Global Year Webinar is on 27th May 8 am EDT. Identification and Clinical Management of Neuropathic Pain: From Evidence to Best Practice. Great speakers and registration is free! perc.iasp-pain.org/products/ide... @iasp-mesisig.bsky.social @efic.bsky.social
perc.iasp-pain.org
International Association for the Study of Pain: Identification and Clinical Management of Neuropathic Pain: From Evidence to Best Practice.
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 22/12/2025
Did you ask Santa for a critical appraisal tool for systematic reviews of prognostic factor studies? The new AMSTAR-PF tool is now published in @bmj.com www.bmj.com/content/391/... Excellent work from Michael Henry @UNISA driving this project. @cochranesmg.bsky.social @jbiebhc.bsky.social
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 04/12/2025
As an accompaniment to this new perspective piece on measuring harms in pain research, the recording of our webinar "Assessing harms in pain research" is now available. @iasp.bsky.social @iasp-mesisig.bsky.social @efic.bsky.social @britishpainsoc.bsky.social perc.iasp-pain.org/methodology-...
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Neil O’Connell @neiloconnell.bsky.social · 02/12/2025
Our recent and excellent @iasp-mesisig.bsky.social webinar "Optimising Openness and Transparency in Pain Research" is now free to view here perc.iasp-pain.org/methodology-...
perc.iasp-pain.org
International Association for the Study of Pain: Methodology, Evidence Synthesis, And Implementation (MESISIG)
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 24/10/2025
New systematic review focused on amputation for complex regional pain syndrome and briliantly led by @yannickgilanyi.bsky.social from UNSW and Neura sciencedirect.com/science/arti... HT @iasp.bsky.social @iasp-mesisig.bsky.social @britishpainsoc.bsky.social @efic.bsky.social @usasp.bsky.social
sciencedirect.com
Amputation for complex regional pain syndrome: a systematic review
Complex regional pain syndrome (CRPS) is a disabling pain condition, usually confined to a single limb. Amputation of the affected limb is sometimes p…
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Reposted by Methods, Evidence Synthesis and Implementation SIG
The British Pain Society @britishpainsoc.bsky.social · 13/10/2025
🚨 BPS Endorses the ENTRUST-PE Framework The British Pain Society is proud to endorse ENTRUST-PE – a framework boosting the trustworthiness, transparency, and rigor of pain research. 🔗Read more: m.entrust-pe.org
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Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 10/10/2025
youtu.be/_zephafiitk?...
youtu.be
What's the point of pain? | BBC Ideas
YouTube video by BBC Ideas
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 09/10/2025
Great to see the OPTIMETH framework for optimising clinical trials in CRPS, brilliantly led by Keith Smart from @ucddublin.bsky.social now out in @painreports.bsky.social journals.lww.com/painrpts/ful... @britishpainsoc.bsky.social @efic.bsky.social @iasp.bsky.social @iasp-mesisig.bsky.social
journals.lww.com
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Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025
Nice piece from @eraneuron.bsky.social about the success of the ENTRUST-PE project, which they supported: www.neuron-eranet.eu/news-publica...
neuron-eranet.eu
ENTRUST-PE: A New Framework for Trustworthy Pain Research - ERA-NET NEURON
NEURON’s Role and Reflections from the First Networking Call The success of ENTRUST-PE also reflects the value of ERA-Net NEURON’s strategic focus on networking and community building. The Networking ...
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Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025
MESISIG is now on BlueSky. We've migrated who we follow (as far as possible) from X but do please follow us back. We promise all things methodology and pain research! www.iasp-pain.org/membership/s...
iasp-pain.org
Methodology, Evidence Synthesis, and Implementation (MESISIG) - International Association for the Study of Pain (IASP)
About > Webinar > Resources > MESISIG LEADERSHIP Chair: Neil O’Connell UK Past Chair: Andrew Moore UK Treasurer: Michael Ferraro AUS Secretary: Emma Fisher UK MESISIG SOCIAL MEDIA MESISIG Mission […]
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Andrew Porter @retropz.bsky.social · 04/04/2025
A new version of the UK Concordat to Support Research Integrity (‘the Concordat’) has been released: ukcori.org/research-int... Now hosted by #UKCORI, the 2025 version was revised through extensive consultation with the #ResearchIntegrity community, summarised in a separate document on the website
Front cover of the updated Concordat To Support Research Integrity - with the main text in white on a mid-blue background, with a background image of interlocking triangles creating a 3D effect
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Hugh Shanahan @hughshanahan.bsky.social · 10/04/2025
The UKRI has published a new draft research data policy. The policy will update and streamline UKRI's expectations for sharing and managing research data and other digital objects, such as software and code. Feedback on the draft can be made here engagementhub.ukri.org/ukri-openres...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Pain and Intellectual and Developmental Disabilities Group @pidd-iasp.bsky.social · 10/03/2025
Just published by Ryan et al. Pain was present for 24% to 89% of adults with cerebral palsy (across studies) with prevalence of chronic pain ranging from 75 to 78%. Communication function, sex, and age were prognostic factors for pain prevalence. onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Pain in adults with cerebral palsy: A systematic review
Aim To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 06/05/2025
From the archives on this www.iasp-pain.org/publications...
iasp-pain.org
Expanding placebo “responses” and the importance of language - International Association for the Study of Pain (IASP)
It seems the possibility that “placebo responses” are getting bigger is newsworthy. A new systematic review just published in the journal PAIN[1] has been receiving a fair amount of attention. The […]
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Sandy Hilton @sandyhiltonpt.bsky.social · 02/06/2025
Enhancing the trustworthiness of pain research: A call to action. - The Journal of Pain www.jpain.org/article/S152... To read by @neiloconnell.bsky.social
jpain.org
Enhancing the trustworthiness of pain research: A call to action.
The personal, social and economic burden of chronic pain is enormous. Tremendous research efforts are being directed toward understanding, preventing, and managing chronic pain. Yet patients with chro...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
JAMA @jama.com · 15/06/2025
Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. ja.ma/3TlnKQe
CONSORT 2025 Statement
Updated Guideline for Reporting Randomized Trials
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Ella Flemyng @ellaflem.bsky.social · 04/06/2025
‼️HOT OFF THE PRESS‼️ ⭐Updated Responsible AI use in Evidence Synthesis (RAISE) 3-paper collection on OSF: osf.io/fwaud/files/... ⭐ Now includes: 1️⃣Recommendations for practice for the main roles in the ecosystem 2️⃣ Guidance on building & evaluating AI tools 3️⃣Guidance on selecting & using AI tools
osf.io
OSF
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Neil O’Connell @neiloconnell.bsky.social · 26/06/2025
Check out this thread on the excellent work @jdwilko.bsky.social is doing to develop tools to assess trustworthiness of clinical trials
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Anaesthesia @anaesjournal.bsky.social · 03/07/2025
Can we trust research? The ENTRUST-PE framework conceptualises the construct ‘trustworthiness’ of research to be supported by 7 core values. From: Editorial commitment to trust and integrity in science: implications for pain and anaesthesiology research #AnSky #MedSky doi.org/10.1111/anae...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Karen Davis @karenddavis.bsky.social · 08/07/2025
Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research journals.lww.com/pain/fulltex...
journals.lww.com
Editorial commitment to trust and integrity in science:... : PAIN
An abstract is unavailable.
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Reposted by Methods, Evidence Synthesis and Implementation SIG
The Journal of Pain @thejournalofpain.bsky.social · 14/07/2025
Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: doi.org/10.1016/j.jp...
doi.org
Redirecting
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PAIN @painthejournal.bsky.social · 14/07/2025
#PAIN joins with other editors of pain-related journals to affirm our editorial commitment to trust and integrity in science. Read our joint statement at bit.ly/4lj3b3b
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 16/07/2025
Delighted that the editors of 15 Pain and Anaesthesiology have chosen to endorse and amplify the ENTRUST-PE framework. More info here: www.linkedin.com/pulse/entrus... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social @ukrio.bsky.social @coarassessment.bsky.social
linkedin.com
ENTRUST-PE: endorsement by senior editors of 15 Pain and Anaesthesiology Journals
We are beyond delighted that the ENTRUST-PE framework has been endorsed by the Editors in Chief of 15 International Pain and Anaesthesiology journals. Those editors are copublishing, across the journa...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 18/07/2025
A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research www.tandfonline.com/doi/full/10....
tandfonline.com
A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research
Published in Journal of Pain Research (Vol. 18, No. , 2025)
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 21/07/2025
Nice piece from Nadia Soliman and Michael Ferraro in MJA Insight on the state of the evidence for the management of neuropathic pain: insightplus.mja.com.au/2025/28/neur...
insightplus.mja.com.au
Neuropathic pain: our best treatments still fall short - InSight+
Despite a large body of new evidence, our best treatments for neuropathic pain continue to provide only modest benefits. Neuropathic pain is a common and disabling condition caused by injury or diseas...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Johannes Gierschner @gierschner.bsky.social · 22/07/2025
👉Predatory Conference Check List 👈 ...based on my experience in detecting difficult cases, I did my own list for our group, as I was missing some points in those available... anyway, I'm happy to get suggestions etc. #researchintegrity #PredatoryConference download: www.uv.es/jogiers/pdf/...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
JAMA @jama.com · 10/08/2025
📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research. ja.ma/4fzMVZS
Figure.  SPIRIT 2025 Diagram of the Schedule of Enrollment, Interventions, and Assessments
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Reposted by Methods, Evidence Synthesis and Implementation SIG
eraneuron.bsky.social @eraneuron.bsky.social · 31/07/2025
Led by Prof. Neil O’Connell and funded by ERA-Net NEURON, ENTRUST-PE brought together an international network to co-create a new framework for trustworthy pain research. Learn more: entrust-pe.org #ENTRUSTPE #ChronicPain #ResearchIntegrity #EquityInResearch #PainResearch #NEURON #SuccessStory #RRI
neuron-eranet.eu
ENTRUST-PE: A New Framework for Trustworthy Pain Research - ERA-NET NEURON
NEURON’s Role and Reflections from the First Networking Call The success of ENTRUST-PE also reflects the value of ERA-Net NEURON’s strategic focus on networking and community building. The Networking ...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
The Journal of Pain @thejournalofpain.bsky.social · 28/07/2025
Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: www.jpain.org/article/S152...
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 03/05/2025
The ENTRUST-Pain Evidence (Entrust-PE) is an important initiative to ensure that pain science is of high quality. Framework published in J Pain. Endorsed by @iasp.bsky.social & @efic.bsky.social. More here: m.entrust-pe.org #pain
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Michael Ferraro @mcferraro.bsky.social · 18/08/2025
Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...
doi.org
Ketamine and other NMDA receptor antagonists for chronic pain - Ferraro, MC - 2025 | Cochrane Library
Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.
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Jack Wilkinson @jdwilko.bsky.social · 05/09/2025
www.medrxiv.org/content/10.1... INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.
medrxiv.org
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....
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Reposted by Methods, Evidence Synthesis and Implementation SIG
Neil O’Connell @neiloconnell.bsky.social · 03/09/2025
To do no harm, we must first “know harms” Our new perspective piece on the challenge of measuring and reporting adverse events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social
dx.doi.org
To do no harm, we must first “know harms”. The challenge of ... : PAIN
An abstract is unavailable.
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Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025
MESISIG is now on BlueSky. We've migrated who we follow 9as far as possible) from X but do please follow us back. We promise all things methodology and pain research!
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