Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 03/06/2026www.linkedin.com/posts/neil-o...linkedin.comJoin us for the first International Association for the Study of Pain MESISIG contribution to the Pain Research Forum Journal Club series where I will be discussing the new ISHOOS consensus… | Neil O&...Join us for the first International Association for the Study of Pain MESISIG contribution to the Pain Research Forum Journal Club series where I will be discussing the new ISHOOS consensus recommenda... 001
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 06/05/2026WEBINAR ALERT! Our next IASP Global Year Webinar is on 27th May 8 am EDT. Identification and Clinical Management of Neuropathic Pain: From Evidence to Best Practice. Great speakers and registration is free! perc.iasp-pain.org/products/ide... @iasp-mesisig.bsky.social @efic.bsky.socialperc.iasp-pain.orgInternational Association for the Study of Pain: Identification and Clinical Management of Neuropathic Pain: From Evidence to Best Practice. 043
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 22/12/2025Did you ask Santa for a critical appraisal tool for systematic reviews of prognostic factor studies? The new AMSTAR-PF tool is now published in @bmj.com www.bmj.com/content/391/... Excellent work from Michael Henry @UNISA driving this project. @cochranesmg.bsky.social @jbiebhc.bsky.sociallnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 043
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 04/12/2025As an accompaniment to this new perspective piece on measuring harms in pain research, the recording of our webinar "Assessing harms in pain research" is now available. @iasp.bsky.social @iasp-mesisig.bsky.social @efic.bsky.social @britishpainsoc.bsky.social perc.iasp-pain.org/methodology-... 033
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 02/12/2025Our recent and excellent @iasp-mesisig.bsky.social webinar "Optimising Openness and Transparency in Pain Research" is now free to view here perc.iasp-pain.org/methodology-...perc.iasp-pain.orgInternational Association for the Study of Pain: Methodology, Evidence Synthesis, And Implementation (MESISIG) 011
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 24/10/2025New systematic review focused on amputation for complex regional pain syndrome and briliantly led by @yannickgilanyi.bsky.social from UNSW and Neura sciencedirect.com/science/arti... HT @iasp.bsky.social @iasp-mesisig.bsky.social @britishpainsoc.bsky.social @efic.bsky.social @usasp.bsky.socialsciencedirect.comAmputation for complex regional pain syndrome: a systematic reviewComplex regional pain syndrome (CRPS) is a disabling pain condition, usually confined to a single limb. Amputation of the affected limb is sometimes p… 001
Reposted by Methods, Evidence Synthesis and Implementation SIGThe British Pain Society @britishpainsoc.bsky.social · 13/10/2025🚨 BPS Endorses the ENTRUST-PE Framework The British Pain Society is proud to endorse ENTRUST-PE – a framework boosting the trustworthiness, transparency, and rigor of pain research. 🔗Read more: m.entrust-pe.org 064
Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 10/10/2025youtu.be/_zephafiitk?...youtu.beWhat's the point of pain? | BBC IdeasYouTube video by BBC Ideas 011
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 09/10/2025Great to see the OPTIMETH framework for optimising clinical trials in CRPS, brilliantly led by Keith Smart from @ucddublin.bsky.social now out in @painreports.bsky.social journals.lww.com/painrpts/ful... @britishpainsoc.bsky.social @efic.bsky.social @iasp.bsky.social @iasp-mesisig.bsky.socialjournals.lww.com 022
Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025Nice piece from @eraneuron.bsky.social about the success of the ENTRUST-PE project, which they supported: www.neuron-eranet.eu/news-publica...neuron-eranet.euENTRUST-PE: A New Framework for Trustworthy Pain Research - ERA-NET NEURONNEURON’s Role and Reflections from the First Networking Call The success of ENTRUST-PE also reflects the value of ERA-Net NEURON’s strategic focus on networking and community building. The Networking ... 010
Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025MESISIG is now on BlueSky. We've migrated who we follow (as far as possible) from X but do please follow us back. We promise all things methodology and pain research! www.iasp-pain.org/membership/s...iasp-pain.orgMethodology, Evidence Synthesis, and Implementation (MESISIG) - International Association for the Study of Pain (IASP)About > Webinar > Resources > MESISIG LEADERSHIP Chair: Neil O’Connell UK Past Chair: Andrew Moore UK Treasurer: Michael Ferraro AUS Secretary: Emma Fisher UK MESISIG SOCIAL MEDIA MESISIG Mission […] 010
Reposted by Methods, Evidence Synthesis and Implementation SIGAndrew Porter @retropz.bsky.social · 04/04/2025A new version of the UK Concordat to Support Research Integrity (‘the Concordat’) has been released: ukcori.org/research-int... Now hosted by #UKCORI, the 2025 version was revised through extensive consultation with the #ResearchIntegrity community, summarised in a separate document on the website 063
Reposted by Methods, Evidence Synthesis and Implementation SIGHugh Shanahan @hughshanahan.bsky.social · 10/04/2025The UKRI has published a new draft research data policy. The policy will update and streamline UKRI's expectations for sharing and managing research data and other digital objects, such as software and code. Feedback on the draft can be made here engagementhub.ukri.org/ukri-openres... 12530
Reposted by Methods, Evidence Synthesis and Implementation SIGPain and Intellectual and Developmental Disabilities Group @pidd-iasp.bsky.social · 10/03/2025Just published by Ryan et al. Pain was present for 24% to 89% of adults with cerebral palsy (across studies) with prevalence of chronic pain ranging from 75 to 78%. Communication function, sex, and age were prognostic factors for pain prevalence. onlinelibrary.wiley.com/doi/full/10....onlinelibrary.wiley.comPain in adults with cerebral palsy: A systematic reviewAim To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for... 012
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 06/05/2025From the archives on this www.iasp-pain.org/publications...iasp-pain.orgExpanding placebo “responses” and the importance of language - International Association for the Study of Pain (IASP)It seems the possibility that “placebo responses” are getting bigger is newsworthy. A new systematic review just published in the journal PAIN[1] has been receiving a fair amount of attention. The […] 001
Reposted by Methods, Evidence Synthesis and Implementation SIGSandy Hilton @sandyhiltonpt.bsky.social · 02/06/2025Enhancing the trustworthiness of pain research: A call to action. - The Journal of Pain www.jpain.org/article/S152... To read by @neiloconnell.bsky.socialjpain.orgEnhancing the trustworthiness of pain research: A call to action.The personal, social and economic burden of chronic pain is enormous. Tremendous research efforts are being directed toward understanding, preventing, and managing chronic pain. Yet patients with chro... 022
Reposted by Methods, Evidence Synthesis and Implementation SIGJAMA @jama.com · 15/06/2025Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. ja.ma/3TlnKQe 05129
Reposted by Methods, Evidence Synthesis and Implementation SIGElla Flemyng @ellaflem.bsky.social · 04/06/2025‼️HOT OFF THE PRESS‼️ ⭐Updated Responsible AI use in Evidence Synthesis (RAISE) 3-paper collection on OSF: osf.io/fwaud/files/... ⭐ Now includes: 1️⃣Recommendations for practice for the main roles in the ecosystem 2️⃣ Guidance on building & evaluating AI tools 3️⃣Guidance on selecting & using AI toolsosf.ioOSF 01215
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 26/06/2025Check out this thread on the excellent work @jdwilko.bsky.social is doing to develop tools to assess trustworthiness of clinical trials 022
Reposted by Methods, Evidence Synthesis and Implementation SIGAnaesthesia @anaesjournal.bsky.social · 03/07/2025Can we trust research? The ENTRUST-PE framework conceptualises the construct ‘trustworthiness’ of research to be supported by 7 core values. From: Editorial commitment to trust and integrity in science: implications for pain and anaesthesiology research #AnSky #MedSky doi.org/10.1111/anae... 043
Reposted by Methods, Evidence Synthesis and Implementation SIGKaren Davis @karenddavis.bsky.social · 08/07/2025Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research journals.lww.com/pain/fulltex...journals.lww.comEditorial commitment to trust and integrity in science:... : PAINAn abstract is unavailable. 086
Reposted by Methods, Evidence Synthesis and Implementation SIGThe Journal of Pain @thejournalofpain.bsky.social · 14/07/2025Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: doi.org/10.1016/j.jp...doi.orgRedirecting 243
Reposted by Methods, Evidence Synthesis and Implementation SIGPAIN @painthejournal.bsky.social · 14/07/2025#PAIN joins with other editors of pain-related journals to affirm our editorial commitment to trust and integrity in science. Read our joint statement at bit.ly/4lj3b3b 053
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 16/07/2025Delighted that the editors of 15 Pain and Anaesthesiology have chosen to endorse and amplify the ENTRUST-PE framework. More info here: www.linkedin.com/pulse/entrus... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social @ukrio.bsky.social @coarassessment.bsky.sociallinkedin.comENTRUST-PE: endorsement by senior editors of 15 Pain and Anaesthesiology JournalsWe are beyond delighted that the ENTRUST-PE framework has been endorsed by the Editors in Chief of 15 International Pain and Anaesthesiology journals. Those editors are copublishing, across the journa... 074
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 18/07/2025A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research www.tandfonline.com/doi/full/10....tandfonline.comA Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation ResearchPublished in Journal of Pain Research (Vol. 18, No. , 2025) 101
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 21/07/2025Nice piece from Nadia Soliman and Michael Ferraro in MJA Insight on the state of the evidence for the management of neuropathic pain: insightplus.mja.com.au/2025/28/neur...insightplus.mja.com.auNeuropathic pain: our best treatments still fall short - InSight+Despite a large body of new evidence, our best treatments for neuropathic pain continue to provide only modest benefits. Neuropathic pain is a common and disabling condition caused by injury or diseas... 011
Reposted by Methods, Evidence Synthesis and Implementation SIGJohannes Gierschner @gierschner.bsky.social · 22/07/2025👉Predatory Conference Check List 👈 ...based on my experience in detecting difficult cases, I did my own list for our group, as I was missing some points in those available... anyway, I'm happy to get suggestions etc. #researchintegrity #PredatoryConference download: www.uv.es/jogiers/pdf/... 044
Reposted by Methods, Evidence Synthesis and Implementation SIGJAMA @jama.com · 10/08/2025📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research. ja.ma/4fzMVZS 03020
Reposted by Methods, Evidence Synthesis and Implementation SIGeraneuron.bsky.social @eraneuron.bsky.social · 31/07/2025Led by Prof. Neil O’Connell and funded by ERA-Net NEURON, ENTRUST-PE brought together an international network to co-create a new framework for trustworthy pain research. Learn more: entrust-pe.org #ENTRUSTPE #ChronicPain #ResearchIntegrity #EquityInResearch #PainResearch #NEURON #SuccessStory #RRIneuron-eranet.euENTRUST-PE: A New Framework for Trustworthy Pain Research - ERA-NET NEURONNEURON’s Role and Reflections from the First Networking Call The success of ENTRUST-PE also reflects the value of ERA-Net NEURON’s strategic focus on networking and community building. The Networking ... 142
Reposted by Methods, Evidence Synthesis and Implementation SIGThe Journal of Pain @thejournalofpain.bsky.social · 28/07/2025Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: www.jpain.org/article/S152... 112
Reposted by Methods, Evidence Synthesis and Implementation SIGMassi(e)h Moayedi — مسیح مویدی @massih.bsky.social · 03/05/2025The ENTRUST-Pain Evidence (Entrust-PE) is an important initiative to ensure that pain science is of high quality. Framework published in J Pain. Endorsed by @iasp.bsky.social & @efic.bsky.social. More here: m.entrust-pe.org #pain 063
Reposted by Methods, Evidence Synthesis and Implementation SIGMichael Ferraro @mcferraro.bsky.social · 18/08/2025Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...doi.orgKetamine and other NMDA receptor antagonists for chronic pain - Ferraro, MC - 2025 | Cochrane LibrarySelect your preferred language for Cochrane reviews and other content. Sections without translation will be in English. 123
Reposted by Methods, Evidence Synthesis and Implementation SIGJack Wilkinson @jdwilko.bsky.social · 05/09/2025www.medrxiv.org/content/10.1... INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.medrxiv.orgINSPECT-SR: a tool for assessing trustworthiness of randomised controlled trialsThe integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings.... 37137
Reposted by Methods, Evidence Synthesis and Implementation SIGNeil O’Connell @neiloconnell.bsky.social · 03/09/2025To do no harm, we must first “know harms” Our new perspective piece on the challenge of measuring and reporting adverse events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.socialdx.doi.orgTo do no harm, we must first “know harms”. The challenge of ... : PAINAn abstract is unavailable. 065
Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 07/10/2025MESISIG is now on BlueSky. We've migrated who we follow 9as far as possible) from X but do please follow us back. We promise all things methodology and pain research! 011