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Cerebral palsy is the most common motor disorder of childhood, leading to lifelong disability and associated comorbidities, including a high incidence of chronic pain. This hypothesis-generating study aimed to (1) investigate a modeling approach to subgrouping based on behavioral reactivity (BR) to …

Pain assessment In Infants and Children

Autistic people can experience distress for many reasons. Some of these reasons may include unsupportive environments; experiences of trauma; sensory overload; burnout, inertia, meltdown and shutdown; pain; and mental health diagnoses such as anxiety. Little is known about how distress can impact co …

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and central pain circuits have been studied, but the peripheral tactile drive has not been explored. Objective: Investigate the innervation of the skin in the rat plantar hindpaw skin–muscle incision model. Results: Incision increased epidermal thickness and cell layers and reduced intraepidermal nerve fibre density, identified with PGP9.5 immunostaining. Strikingly, Collagen IV immunostaining revealed the development of dermal protrusions, oriented towards the incision site, that w...

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Individuals with autism spectrum disorder (ASD) have long been reported to exhibit atypical pain experiences. Chronic physical pain is a significant comorbidity in ASD, leading to substantial burdens on daily functioning and quality of life. This study aims to examine the potential associations between ASD and chronic physical pain, including its specific types. The study used data on chronic physical pain and headaches from the 2016 – 2021 National Survey of Children’s Health. Participants w...

This review is made up of two parts; the first part discussing intellectual disability (ID) in general, while the second part covers the pain associated with intellectual disability and the challenges and practical tips for the management of pain associated with (ID). Intellectual disability is characterized by deficits in general mental abilities, such as reasoning, problem solving, planning, abstract thinking, judgment, academic learning, and learning from experience. ID is a disorder with ...

Background: Families with children with medical complexity endure high levels of chronic and toxic stress, impacting the overall health and wellbeing of all family members and the system as a whole. The purpose of this study was to examine the lived ...

This report describes autism spectrum disorder prevalence and early identifications patterns among children aged 4 and 8 years old.

To examine sex differences in neurodevelopmental outcomes and brain development from early life to 8 years in males and females born preterm.This was …

Autistic adolescents are at greater risk of chronic pain, but it is unclear how autistic features may relate to individual aspects of chronic pain. As…

Autistic patients can have different communication and sensory needs, potentially making orthopaedic visits stressful. This study evaluated which fact…

Aim To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for...

Association with thalamic volume loss suggests that neuropathic pain in adults with CP may frequently be central neuropathic pain. Complementing assessments of white matter microstructure, regional br...

Children with cerebral palsy (CP) can experience a substantial amount of pain. Effective pain management hinges on precise and prompt assessment. We d…

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