In the prospective, multicentre TEDDY study, distinct patterns of gut microbiome maturation are associated with differential risk of type 1 diabetes, with host genetics modifying the strength of this ...

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Recent work in Gut has highlighted multi-kingdom interactions between gut bacteria and bacteriophage (‘phage’) as contributors to Crohn’s disease.1 Whether similar alterations characterise colorectal ...

Nature Methods - Getting over ANOVA: estimation graphics for multi-group comparisons

Coupled with well-characterized host genetic and environmental risk factors, alterations of gut microbial communities contribute to risk and severity …

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Nogal et al. profile the gut microbiome and metabolome of individuals with a history of colorectal adenoma resection, revealing microbial and metabolic alterations detectable more than a decade after ...

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Gallego-del-Sol et al. show that arbitrium-coding phages can sense non-cognate peptide signals from other phages to regulate lysis-lysogeny decisions. This crosstalk affects lysis-lysogeny outcomes of phage infections, mixed lysogenic communities, and polylysogens. Our results demonstrate that crosstalk is an important mechanism that drives phage interactions in microbial communities.