iiinova — where your digital self keeps evolving

Reposted by HittingerLab

University of Guelph News @uofguelphnews.bsky.social · 21/05/2026

Resistance to antifungal medications is growing. Now, #UofG researchers have developed a faster way to identify the genetic vulnerabilities of Candida fungi, which could lead to brand new treatments. @uofgcbs.bsky.social @uofgresearch.bsky.social uoguel.ph/vze5i

uoguel.ph

Faster Gene Screening Method Targets Deadly Fungus

U of G researchers are using CRISPR interference to spot genetic vulnerabilities in Candida albicans, a leading cause of life-threatening infections.

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HittingerLab @hittingerlab.bsky.social · 31/08/2026

The new lab opens 1st July 2027 a bit to the east of the current lab, across the border and on the other side of the Great Lakes in Guelph, Ontario, which is near Toronto. Watch for recruitment opportunities at all levels! @UofGuelphNews, @UofG, @UofGResearch

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HittingerLab @hittingerlab.bsky.social · 31/08/2026

I am honored to be chosen as the new Eddie Goldenberg Research Chair of Canada in Biodiscovery, Biodesign, and Bioproduction at University of Guelph as part of the Canada Global Impact+ Research Talent Initiative! @UofGuelphNews, @UofG, @UofGResearch

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Reposted by HittingerLab

University of Guelph @uofguelph.bsky.social · 27/08/2026

Backed by $8M in federal funding, Dr. Chris Todd Hittinger will be the new Eddie Goldenberg Research Chair of Canada in Biodiscovery, Biodesign and Bioproduction at #UofG as part of the Canada Global Impact+ Research Talent Initiative. His appointment begins on July 1, 2027: uoguel.ph/3nw8s

Dr. Chris Todd Hittinger stands against a dark background, smiling slightly at the camera.

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HittingerLab @hittingerlab.bsky.social · 14/07/2026

You can also download this highlight on the GLBRC website linked above:

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HittingerLab @hittingerlab.bsky.social · 08/07/2026

A tenure-track research position is available for application at the Westerdijk Fungal Biodiversity Institute @westerdijkinst.bsky.social located in Utrecht Science Park in the Netherlands. Please share with colleagues and see the link below for more info: wi.knaw.nl/news/details...

wi.knaw.nl

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HittingerLab @hittingerlab.bsky.social · 24/06/2026

A new study out with @linder-surprise.bsky.social and @rokaslab.bsky.social in iScience across ~300 yeast species confirms the correlation between glucose uptake rate and cell surface-to-volume (SA:V) ratio, but suggests a link to other traits (growth rates and genome size). doi.org/10.1016/j.is...

sciencedirect.com

A trait syndrome ties cell morphology to glycolysis across the yeast subphylum

Co-variation of traits provides fundamental insights into constraints governing their evolution. An inverse correlation between glucose uptake rates (…

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HittingerLab @hittingerlab.bsky.social · 24/06/2026

Check out this new first-author paper from our new postdoctoral lab member @alyahussain.bsky.social! 🎉 This work is from her PhD in the Michael McMurray lab at CU Anschutz.

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HittingerLab @hittingerlab.bsky.social · 08/06/2026

Two members of the Hittinger Lab received awards during the annual All-Wisconsin Energy Institute (WEI) meeting. Our lab manager, Amanda Hulfachor, won the Excellence Award and Sam Davison, a CMB graduate student, won the award for Community Impact. Congrats to both - we are very proud!⭐⭐⭐

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HittingerLab @hittingerlab.bsky.social · 09/05/2026

Please pass this message along to fellow colleagues who you think would be interested in attending! Available spots are filling up quickly. Don’t miss the opportunity to secure your place at a reduced rate. Once the deadline passes or capacity is reached, standard registration rates will apply.

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Reposted by HittingerLab

Physiology of Yeasts and Filamentous Fungi @pyff-9.bsky.social · 04/11/2025

#PYFF9 is coming to Valencia! 🇪🇸 Join us for the 9th International Conference on Physiology of Yeasts and Filamentous Fungi (PYFF9), Sept 8–11, 2026! ✨ Cutting-edge science, vibrant networking, and the charm of the Mediterranean—don’t miss it! 🔗 Learn more: efbiotechnology.org/pyff

efbiotechnology.org

PYFF

Physiology of Yeasts and Filamentous Fungi (PYFF) conference will take place in Valencia, Spain. It brings together researchers from academia and industry who are engaged in the study of the physiolog...

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Reposted by HittingerLab

Linda Horianopoulos @linder-surprise.bsky.social · 30/04/2026

There's a story behind every project that doesn't get fully captured in the final paper. Check out our "behind the paper" accompanying our paper on convergent evolution of aerobic fermentation in yeast. communities.springernature.com/posts/learni... @hittingerlab.bsky.social @rokaslab.bsky.social

communities.springernature.com

Learning the rules of metabolic innovation in yeast evolution

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Reposted by HittingerLab

The EMBO Journal @embojournal.org · 10/04/2026

Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes @hittingerlab.bsky.social , @linder-surprise.bsky.social et al show how distinct genetic routes can converge on the same genetic outcome link.springer.com/article/10.1...

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HittingerLab @hittingerlab.bsky.social · 26/02/2026

Congratulations to @maxhaase.bsky.social on his recent publication from his time in the Boeke Lab at NYU, where he used methods from the Y1000+ consortium! 🥳 We are very proud to have had him as an undergraduate student in our lab. med.nyu.edu/research/boe...

med.nyu.edu

Boeke Lab Team | NYU Langone Health

NYU Langone’s Boeke Lab comprises faculty, postdoctoral fellows, graduate students, and research staff who synthesize an engineered yeast genome.

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HittingerLab @hittingerlab.bsky.social · 04/02/2026

With the @rokaslab.bsky.social, three novel whole genome duplication (WGD) events were discovered in the Saccharomycotina yeast species in the Dipodascales clade. Before now, only four WGD events were known in fungi. This work suggests WGD may be underreported. www.sciencedirect.com/science/arti...

sciencedirect.com

Discovery of additional ancient genome duplications in yeasts

Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

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HittingerLab @hittingerlab.bsky.social · 27/01/2026

We're excited to announce that Chris will be attending the Yeast Genetics Meeting organized by the Genetics Society of America (GSA) @genetics-gsa.bsky.social in CA on June 13-17! #Yeast26 If you are interested in attending or presenting, follow this link to register! genetics-gsa.org/yeast-2026/

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HittingerLab @hittingerlab.bsky.social · 23/01/2026

How much do growth morphologies in the Saccharomycotina subphylum vary? 🤔 With the @rokaslab.bsky.social, integrated datasets of 1,051 species were examined to assess filamentation evol. history and variation. ML models predicted morphologies with 70% accuracy. academic.oup.com/femsyr/advan...

media.tenor.com

a group of people are standing next to each other in front of a wall .

ALT: a group of people are standing next to each other in front of a wall .

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HittingerLab @hittingerlab.bsky.social · 15/01/2026

In collaboration with the Pfleger Lab, Josh Dietrich et al. investigated 2-ketoacid decarboxylase (KDC) substrate specificities to identify KDCs with preference for 2-ketoisovalerate over pyruvate. This work will help guide future S. cerevisiae engineering efforts. urldefense.com/v3/__http://...

urldefense.com

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HittingerLab @hittingerlab.bsky.social · 09/12/2025

Congratulations to our wonderful PI, Chris Todd Hittinger, on receiving the Vilas Mid-Career Investigator Award from the UW–Madison Laboratory of Genetics! This recognition highlights his continued excellence in research, teaching, training, and mentorship. 🎉 genetics.wisc.edu/2025/12/09/d...

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HittingerLab @hittingerlab.bsky.social · 08/12/2025

If you are interested in being added to the mailing list for Yeast, follow this link to sign-up. urldefense.com/v3/__http://...

urldefense.com

Yeast Newsletter

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HittingerLab @hittingerlab.bsky.social · 08/12/2025

We were featured in the Yeast Newsletter, published in June and December every year with Western University, serving as an informal communication method for those interested in all things yeast-biology. Checkout pages 18-23! www.uwo.ca/biology/Yeas...

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HittingerLab @hittingerlab.bsky.social · 11/11/2025

New work led by members of the @rokaslab.bsky.social! ☺️ 1,154 yeast genomes in the Saccharomycotina subphylum were surveyed for their relationship between reduced gene repertoires broadly associated with genome stability functions and elevated evolutionary rates.🧬 academic.oup.com/mbe/advance-...

academic.oup.com

Stable hypermutators revealed by the genomic landscape of genes involved in genome stability among yeast species

Abstract. Mutator phenotypes are short-lived due to the rapid accumulation of deleterious mutations. Yet, recent observations reveal that certain fungi can

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HittingerLab @hittingerlab.bsky.social · 11/11/2025

Together, these studies help unravel the metabolic, genomic, and morphological diversity found across yeast species and reveal how evolution can both shape and constrain the traits that emerge.

media.tenor.com

a man in a blue shirt and tie is pointing at a bulletin board with a lot of papers on it .

ALT: a man in a blue shirt and tie is pointing at a bulletin board with a lot of papers on it .

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HittingerLab @hittingerlab.bsky.social · 11/11/2025

This work is also follow-up to our previously posted article, led by @linder-surprise.bsky.social: bsky.app/profile/hitt...

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HittingerLab @hittingerlab.bsky.social · 11/11/2025

With @linder-surprise.bsky.social and the @rokaslab.bsky.social, we recently expanded upon an analysis where glucose uptake rates were inversely correlated with the cell surface area-to-volume ratio, testing 282 species in the Saccharomycotina yeast subphylum. www.biorxiv.org/content/10.1...

biorxiv.org

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HittingerLab @hittingerlab.bsky.social · 07/10/2025

ECAR variation is associated with glycolyitc genes across the yeast subphylum (Figure 1 in this work)

https://www.biorxiv.org/content/10.1101/2025.10.02.679963v2

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Reposted by HittingerLab

HittingerLab @hittingerlab.bsky.social · 07/10/2025

This work has also been featured on the DOE Science News Source initiative, Newswise, which promotes credible research news to the public. By publishing accessible summaries of recent studies that reach thousands of media outlets, it helps experts share their work with a broader audience.

newswise.com

Machine Learning Reveals Genes That Help Yeasts Resist Stress

Scientists used machine learning to analyze the genetic blueprints of hundreds of yeasts. This analysis allowed them to identify which groups of genes are most important for resistance to reactive oxy...

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HittingerLab @hittingerlab.bsky.social · 07/10/2025

newswise.com

Machine Learning Reveals Genes That Help Yeasts Resist Stress

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HittingerLab @hittingerlab.bsky.social · 07/10/2025

We are honored to share that our work, led by @katarina-aranguiz.bsky.social and @linder-surprise.bsky.social, has been featured as a Science Highlight on the DOE's Office of Science website. 200 articles are selected annually to be highlighted. Check it out! 🧫 www.energy.gov/science/ber/...

energy.gov

Machine Learning Reveals Genes That Help Yeasts Resist Stress

Study provides a framework for connecting genetic mechanisms and trait variation across diverse yeast species.

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HittingerLab @hittingerlab.bsky.social · 17/09/2025

We report evidence of three previously unknown whole genome duplications (WGD) in Dipodascales yeasts. These events show striking parallels to the WGD of Saccharomyces cerevisae, the only known ancient WGD in the yeast subphylum Saccharomycotina.

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HittingerLab @hittingerlab.bsky.social · 04/09/2025

With the Opulente Lab at Villanova Univ., we describe a new yeast species: Lachancea rosae sp. nov. f.a., isolated from the hip bud of a wild California rose 🌹. This species unique traits adds to the biodiversity of the Lachancea genus. Open access article: onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Taxogenomic Analysis of a Novel Yeast Species, Lachancea rosae Sp. Nov. F.A., Isolated From the Wild Rose Rosa californica

The discovery, description, and taxogenomic analysis of a novel species of Lachancea revealed correlations between gene content and carbon and nitrogen physiological assays.

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HittingerLab @hittingerlab.bsky.social · 14/08/2025

We’re excited to share our latest paper, an international collaboration led by Katharina O. Barros and Jassim Al-Oboudi, describing Pichia senei sp. nov., a novel yeast species isolated from cactus necrosis and bromeliad phytotelmata in Brazil’s Cerrado ecosystem. 🌵🇧🇷

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