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Ian Henderson

@hendersi.bsky.social
2.1K followers 1.9K following 124 posts

Plant genetics and epigenetics @ University of Cambridge, Department of Plant Sciences

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Reposted by Ian Henderson
New Phytologist @newphyt.bsky.social · 07/08/2026
#TansleyReview: The evolutionary origins of streptophyte multicellularity de Vries et al. 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... #LatestIssue #PlantScience @jandevries.bsky.social @caeciliafkunz.bsky.social
Fig. 1 Phylogeny of streptophytes and the deep origin of branching filamentous growth.
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Ian Henderson @hendersi.bsky.social · 25/07/2026
CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.6... new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis
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Ian Henderson @hendersi.bsky.social · 22/06/2026
Cambridge lido is very pleasant !
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Ian Henderson @hendersi.bsky.social · 10/04/2026
Testing Weismann’s germ plasm theory in Arabidopsis www.cell.com/current-biol... super nice lineage tracing work - do plants have a germline? @currentbiology.bsky.social
cell.com
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Reposted by Ian Henderson
Ben Williams @benpwilliams.bsky.social · 31/03/2026
We have been cooking up this story for a while and we are excited to finally be able to share! Read on if you're interested in whole plant regeneration WITHOUT the application of hormones!
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Ian Henderson @hendersi.bsky.social · 28/03/2026
www.theguardian.com/environment/...
theguardian.com
Cambridge offers botany course that inspired Darwin after rare archive uncovered
University’s botanic garden will use study materials created by John Stevens Henslow, the naturalist’s mentor, 200 years ago
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Brett Baker @archaeal.bsky.social · 13/03/2026
Having a hard time keeping up with the fast-moving field of origin of eukaryotes/Asgards archaea? Our new perspective article can help, we review the status of research over the last decade and where it's going. The archaeal roots of eukaryotic life www.pnas.org/doi/10.1073/...
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James McCulloch @jamesimcc.bsky.social · 03/03/2026
Why do the chromosomes of cyperids (sedges & rushes) split and fuse so regularly on evolutionary timescales? Is it because they have so many centromeres? Our new preprint, the first major paper of my PhD, addresses this question. 🧵⬇️ 1/12 www.biorxiv.org/content/10.6...
A sedge. It may look unassuming but its genome has several unusual features.
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Reposted by Ian Henderson
James McCulloch @jamesimcc.bsky.social · 03/03/2026
Thank you to my co-authors: @marcelauliano.bsky.social, @charlottewright.bsky.social, @hendersi.bsky.social, Sam Ebdon, @kamilsjaron.bsky.social & Mark Blaxter. Finally, this would not have been possible without the Darwin Tree of Life sequencing & assembly teams @sangerinstitute.bsky.social! 🧵12/12
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Reposted by Ian Henderson
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 15/01/2026
Exciting News! 🚀 Registration Open! | Loke CTR Annual Meeting 2026 🎉 📅 16-17 July 2026 📍 St John’s College, Cambridge | 💻 Hybrid conference (in-person & online) 🔬 Epigenetics of embryogenesis and placentation 📌 To find out more and to register www.trophoblast.cam.ac.uk/ctrconferenc...
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Reposted by Ian Henderson
Genetics Society of America @genetics-gsa.bsky.social · 16/02/2026
A new study in #GENETICS from @hendersi.bsky.social’s group explores how natural variation in #Arabidopsis influences centromere-proximal crossover frequency and segregation distortion when #centromeres are heterozygous. buff.ly/Ev5Xrro
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Reposted by Ian Henderson
Genetics Society UK @gensocuk.bsky.social · 05/02/2026
Come celebrate our Anniversary Day in Edinburgh, 25 & 26 June! Join us for talks from our Honorary Members, Prize & Medal winners, and our Summer Students. Programme & registration details: genetics.org.uk/events/anniv...
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Ian Henderson @hendersi.bsky.social · 13/01/2026
Lovely gift of Xiao Qing Gan tea which I shall enjoy!
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Ian Henderson @hendersi.bsky.social · 26/12/2025
Repetitive seashore?
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Ian Henderson @hendersi.bsky.social · 21/12/2025
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Reposted by Ian Henderson
Michael Brockhurst @brockhurstlab.bsky.social · 20/12/2025
Manchester Institute of Biotechnology is looking for a new Professor. There are a few priority areas including microbial engineering (broadly defined, from pathways to cells to microbiomes). Closing 12 Jan. Join us in the best city in the UK 😜 www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Professorial Appointment within the Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
Applications are invited for a professorial appointment to be based in the Manchester Institute of Biotechnology (MIB) at the University of Manchester (UoM). The successful candidate will join a dynamic research environment at an exciting time and will help shape the institute research priorities and national/international profile. We are open to high quality applications from across the broad engineering biology and biotechnology landscape. Specific areas of interest include but are not limited to chemical biology of disease related proteins, natural product biosynthesis and enzyme discovery; structural biology and mechanistic enzymology; and microbial engineering.
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Reposted by Ian Henderson
School of Biological Sciences @cambridgebiosci.bsky.social · 09/12/2025
Read more about the projects: www.cam.ac.uk/research/new...
cam.ac.uk
Eight Cambridge researchers awarded €17 million in ERC Consolidator Grants
Funding from the European Union’s Horizon Europe programme will support promising mid-career scientists to pursue creative research ideas across a broad range
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Ian Henderson @hendersi.bsky.social · 08/12/2025
Monday morning dot plot...
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Ian Henderson @hendersi.bsky.social · 04/12/2025
Interesting study suggesting that nucleus, cytoskeleton, and endomembranes preceded acquisition of mitochondria, during eukaryogenesis www.nature.com/articles/s41...
nature.com
Dated gene duplications elucidate the evolutionary assembly of eukaryotes - Nature
Analysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...
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Ian Henderson @hendersi.bsky.social · 27/11/2025
Rapid compensatory evolution within a multiprotein complex preserves telomere integrity www.science.org/doi/10.1126/... @levine-lab.bsky.social very cool work
science.org
Rapid compensatory evolution within a multiprotein complex preserves telomere integrity
Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...
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Ian Henderson @hendersi.bsky.social · 25/11/2025
Amazing work - congrats !!
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Reposted by Ian Henderson
Lars Jansen Lab @jansenlab.bsky.social · 25/11/2025
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration. www.nature.com/articles/s41...
differential contribution of H3K9 methyltransferases to boundaries at satellites
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Reposted by Ian Henderson
Vangeli Geshkovski @vgeshkovski.bsky.social · 21/11/2025
What a nice coincidence to have Kelly Dawe present his work on karyotype engineering for todays seminar @thesainsburylab.bsky.social @johninnescentre.bsky.social
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Ian Henderson @hendersi.bsky.social · 21/11/2025
Genetics Society Anniversary Day 25-26th June, Edinburgh genetics.org.uk/events/anniv... Society Prize Winners: Hilary Martin, Joe Felsenstein, Richard Durbin, Zam Iqbal Honorary Members: Brian Charlesworth, Deborah Charlesworth, Kay Davies, Paul Nurse, David Sherratt, Veronica van Heyningen
genetics.org.uk
Anniversary Day 2026 | Genetics Society
We will celebrate the Genetics Society Anniversary Day in Edinburgh, June 25th-26th, 2026. The event will celebrate with talks from our Honorary Members, 2026 Prize and Medal winners, and Summer Stud...
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Ian Henderson @hendersi.bsky.social · 21/11/2025
Chromosome Dynamics 2026 @ Awaji Japan www.fbs.osaka-u.ac.jp/labs/fukagaw...
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Ian Henderson @hendersi.bsky.social · 20/11/2025
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis | Science www.science.org/doi/10.1126/... Very nice work from Holger Puchta & colleagues
science.org
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis
The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...
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Reposted by Ian Henderson
Genetics Society UK @gensocuk.bsky.social · 13/11/2025
Nobel Prize winner Svante Pääbo giving the Genetics Society public lecture at @crick.ac.uk. Svante is recounting how Neandertals and Denisovans live on in many of us!
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Reposted by Ian Henderson
Genetics Society UK @gensocuk.bsky.social · 14/11/2025
Congratulations @hilarycmartin.bsky.social from @sangerinstitute.bsky.social on being awarded the 2026 Balfour Lecture!
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Genetics Society UK @gensocuk.bsky.social · 14/11/2025
Congratulations to @zaminiqbal.bsky.social from @milnerevolution.bsky.social on being awarded the 2026 Mary Lyon Medal!
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Genetics Society UK @gensocuk.bsky.social · 14/11/2025
Congratulations to @vinuesalab.bsky.social from @crick.ac.uk on winning the 2026 JBS Haldane Lecture. Carola will present her JBS Haldane Lecture next year at @rigb.org!
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Reposted by Ian Henderson
Genetics Society UK @gensocuk.bsky.social · 14/11/2025
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal!
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Reposted by Ian Henderson
Genetics Society UK @gensocuk.bsky.social · 14/11/2025
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
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Ian Henderson @hendersi.bsky.social · 12/11/2025
It’s a patch of centromere dna sequence compared against itself - glad you like it !
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Ian Henderson @hendersi.bsky.social · 12/11/2025
It’s a close up dot plot of a centromere , a region of the chromosome required for segregation, in this case composed of transposon nests.
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Ian Henderson @hendersi.bsky.social · 11/11/2025
FastGA -> ALNview; step into the centromeric matrix! github.com/thegenemyers Probably the best dot plot software on the planet...
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Ian Henderson @hendersi.bsky.social · 08/11/2025
A truly special meeting; the walks in the woods in the evening by moonlight were even more magical. I absorbed a tremendous amount of information; the level or openness and sharing was wonderful; thanks for organising Julius!
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Reposted by Ian Henderson
Tanmay Bharat @tbharat-lab.bsky.social · 07/11/2025
An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...
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Julius Brennecke @juliusbrennecke.bsky.social · 07/11/2025
Some impressions from the rather fabulous #EMBOmobilegenome Mobile Genome meeting in Heidelberg Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, … @events.embl.org The transposon community is going very strong. see you all again in 2027!!
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Reposted by Ian Henderson
Patrick Pausch @patrick-pausch.bsky.social · 06/11/2025
After 5 years of waiting, the new #CRISPR classification by Makarova et al. is out @natmicrobiol.nature.com www.nature.com/articles/s41...
nature.com
An updated evolutionary classification of CRISPR–Cas systems including rare variants - Nature Microbiology
An exploration of previously undescribed variants from the long tail of the CRISPR–Cas distribution.
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Reposted by Ian Henderson
Jolyon Troscianko @jtroscianko.bsky.social · 06/11/2025
BehaveAI is live! Our biologically inspired video analysis tool sees motion as colour. Track animals or objects, classify their behaviour, and handle complex natural scenes with ease. Semi-supervised annotation, no GPUs required, user-friendly, free & open source. Pre-print tinyurl.com/BehaveAI
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Reposted by Ian Henderson
Gregor Mendel Institute of Molecular Plant Biology @gmivienna.bsky.social · 06/11/2025
Magnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes. Read more: www.oeaw.ac.at/gmi/news-eve...
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Jake Harris @c-jake-harris.bsky.social · 05/11/2025
Very excited to share our work published in Nature Comms last week! Here we describe a range of cool things that can be done once you have the power to control deposition of H3K4me3… rdcu.be/eNEf4 A short thread:
rdcu.be
CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis
Nature Communications - Binenbaum et al. demonstrate that precise CRISPR-based targeting of a key chromatin mark (H3K4me3) can switch on genes, boost disease resistance, and unlock meiotic...
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James Davies @jojdavies.bsky.social · 05/11/2025
Our latest paper has just been published in Cell! doi.org/10.1016/j.ce... We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
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Julius Brennecke @juliusbrennecke.bsky.social · 04/11/2025
great to be at the #EMBOMobileGenome meeting in Heidelberg with a wonderful bunch of colleagues, speakers and attendees. this meeting is a good reflection of the excitement and collegiality in the transposon field. kindly sponsored by @embo.org
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Ian Henderson @hendersi.bsky.social · 02/11/2025
😀 see you in a day or two Deborah!
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Ian Henderson @hendersi.bsky.social · 02/11/2025
Active ingredient sodium bisulfite ?
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Ian Henderson @hendersi.bsky.social · 02/11/2025
‘Epigenetic serum’ makes you wonder !
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Reposted by Ian Henderson
Svetlana Dodonova @dodonova-sveta.bsky.social · 28/10/2025
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
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