Abstract. Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordinatio

Behind every research paper, there is a long story that is usually invisible to the reader. Our paper is no exception. What began as a focused cell biology project gradually developed into a broad, co...

——– What we work withWe study early Xenopus frog embryos: a powerful model for developmental biology. 🐸 Why frogsTheir embryos are large, develop outside the body, and are ideal for live imaging and e...

We mapped PRICKLE1–3 interactomes and identified PRICKLE3 as a key WNT/PCP regulator that stabilizes VANGL via CK1ε–RNF43 control, revealing a PRICKLE3-specific mechanism shaping polarity across verte...

Fluconazole (FLU) is a widely used antifungal agent frequently detected in surface waters because of its extensive use in medicine, agriculture, and personal care products.Despite concerns about its persistence and developmental toxicity in aquatic species, its effects on amphibians remain poorly un …

Doctoral study program Life Sciences (Faculty of Science, Masaryk University) Research area Nucleic acid structural biology Supervisor Lukáš Trantírek, Ph.D. Consultant   Anirban Ghos...