Alice Kane on aging, frailty, and healthspan, highlighting new biomarkers, sex differences, and insights into menopause and women’s health.

The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the...

The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the ...

Abstract. Anthropogenic perturbations to the nitrogen cycle, primarily through use of synthetic fertilizers, is driving an unprecedented increase in the em

Exclusive: Melbourne team demonstrates way to make the virus visible within white blood cells, paving the way to fully clear it from the body A cure for HIV could be a step closer after researchers found a new way to force the virus out of hiding inside human cells. The virus’s ability to conceal itself inside certain white blood cells has been one of the main challenges for scientists looking for a cure. It means there is a reservoir of the HIV in the body, capable of reactivation, that neither the immune system nor drugs can tackle. Continue reading...

ISB is saddened to share the passing of Valerie Logan Hood, whose lifelong dedication to K-12 education shaped ISB’s education programs.

openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

The Stand Up for Science rally in Seattle, part of a nationwide effort, filled the mural amphitheater at the Seattle Center. (Photo courtesy of Bryn

The Institute for Systems Biology (ISB) is creating the future of health. ISB scientists make breakthrough discoveries in cancer, health, chronic and infectious disease, and environmental issues. The ...

ISB is a non-profit biomedical research organization based in Seattle, and focuses on some of the most pressing issues in human health. The Health & Safety Specialist is a Lead role responsible fo...

Success of phage therapies is limited by bacterial defenses against phages. While a large variety of anti-phage defense mechanisms has been characterized, how expression of these systems is distribute...

Background Aging is a complex process that involves all tissues in an organism and shows sex dimorphism. While transcriptional changes in aging have been well characterized, the majority of studies ha...

Absolute bacterial biomass estimation in the human gut is crucial for understanding microbiome dynamics and host-microbe interactions. Current methods for quantifying bacterial biomass in stool, such ...

YouTube video by Jess of the Shire

New peer-reviewed research out of ISB highlights the strengths of large language models in uncovering social determinants of health while underscoring the need for human oversight and improved de-iden...