iiinova — where your digital self keeps evolving

Reposted by Jon Agirre

Structural Biology Communications @actacrystf.iucr.org · 13/08/2026

Presenting the first article in our new 'Protocols' category: Helical reconstruction of amyloids in cryoSPARC #Amyloids #CryoEM #HelicalReconstruction doi.org/10.1107/S205...

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Reposted by Jon Agirre

Structural Biology Communications @actacrystf.iucr.org · 06/08/2026

August issue is out! journals.iucr.org/f/issues/202... On the cover: the crystal structure of LegY, a putative glycosidase effector from Legionella pneumophila, shows high similarity to fungal glucoamylases but shares lower homology with known prokaryotic counterparts doi.org/10.1107/S205...

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Jon Agirre @glycojones.bsky.social · 05/08/2026

Ok, time to feel old – for a good cause 😃 I was in the middle of my PhD when our journal was launched. An online-only journal at a time when most others were not. This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!

journals.iucr.org

(IUCr) Submit an article to a special issue

Submit an article to a special issue

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Jon Agirre @glycojones.bsky.social · 04/08/2026

Some questions for our structural biology community: What protocols do you think would be useful to have? Do you prefer to watch step-by-step videos, or follow written instructions? Of course, not everything has to be a video, but certain workflows are simply best documented on video #protocols

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Structural Biology Communications @actacrystf.iucr.org · 29/07/2026

We're celebrating 20 years of Acta Crystallographica Section F!🎉🥳 Join us by contributing to our celebratory collection of articles, which is now open for submissions! Find out more at journals.iucr.org/special_issu...

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Structural Biology Communications @actacrystf.iucr.org · 30/07/2026

A new type of article for Acta F: Protocols The purpose of this new category is to provide to the reader procedures that are sufficiently detailed so other researchers can reproduce the described workflow. Find out more in 'Show me how it's done: introducing Protocols': doi.org/10.1107/S205...

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Goran Bajic @gogo-science.bsky.social · 12/07/2026

Cannot wait to try this out! Thanks @crolltristan.bsky.social and @glycojones.bsky.social !

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Jon Agirre @glycojones.bsky.social · 13/05/2026

In our latest episode of Interviews With Authors, we discussed PentatricoPeptide Repeat (PPR) proteins, their roles in RNA binding, use in protein design and other things, and I'd like to share some highlights. What are PPR proteins and why do they matter, you may ask? Anuradha has the answers:

youtube.com

Structural Insights into PPR Proteins and RNA Recognition

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 13/05/2026

youtube.com

Structural Insights into PPR Proteins and RNA Recognition

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 12/05/2026

It was lovely to chat with Anu and @charliebondxray.bsky.social about PPR proteins, their RNA binding modes and awesome modularity. Please watch, give the IUCr a thumbs up, and add some comments when you have a minute! What would you like to see in these interviews?

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Reposted by Jon Agirre

Structural Biology Communications @actacrystf.iucr.org · 06/01/2026

Have you checked out our latest Interview with Authors? The Editors chat to Mike Cianfrocco, Scott Stagg and Jan-Hannes Schäfer about their CryoSift tool youtu.be/ROlc_eueYfg More interviews at are available at www.youtube.com/playlist?lis...

youtu.be

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

Jon Agirre @glycojones.bsky.social · 22/10/2025

One of the coolest things going on here is that the GitHub repos contain Jupyter notebooks for you to try their software. In case you don't have Jupyter installed or don't know what it is: you can always upload the notebooks to Google Colab and run everything on their cloud services :)

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Reposted by Jon Agirre

Jon Agirre @glycojones.bsky.social · 11/12/2025

New interview alert! We had a chat with Mike Cianfrocco, Scott Stagg and Jan-Hannes Schäfer about their CryoSift tool – details in the thread. www.youtube.com/watch?v=ROlc...

youtube.com

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

Jan-Hannes Schaefer @jhschaef.bsky.social · 11/12/2025

Thanks to @actacrystf.iucr.org for highlighting our smart 2D selection tool CryoSift. You can test it yourself here cryosift.org

cryosift.org

CryoSift - Cryo-EM 2D Classifier

Automated cryo-EM 2D class evaluation and sorting with AI.

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Jon Agirre @glycojones.bsky.social · 11/12/2025

New interview alert! We had a chat with Mike Cianfrocco, Scott Stagg and Jan-Hannes Schäfer about their CryoSift tool – details in the thread. www.youtube.com/watch?v=ROlc...

youtube.com

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 22/10/2025

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Jon Agirre @glycojones.bsky.social · 10/10/2025

Great to see this article by @guptapenn.bsky.social is out! Kushol helped us interview @xtalmaker.bsky.social Vivian Stojanoff and @gabbygrowsxtals.bsky.social who published an article on careful sample preparation in crystallisation experiments, also part of #SAMPREP www.youtube.com/watch?v=m34R...

youtube.com

Preparing for successful protein crystallization experiments

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

Jon Agirre @glycojones.bsky.social · 24/09/2025

I'm incredibly proud to present this @actacrystf.iucr.org interview with Alex Mendez and Cydni Bolling on their first paper ever! The interview was co-led by Dr Graham Chakafana from Hampton University in the USA, who supervised the authors' undergraduate research. www.youtube.com/watch?v=5rjI...

youtube.com

Structure of Plasmodium vivax N-myristoyltransferase with the NMT inhibitor IMP-1088

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 24/09/2025

youtube.com

Structure of Plasmodium vivax N-myristoyltransferase with the NMT inhibitor IMP-1088

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

Structural Biology Communications @actacrystf.iucr.org · 12/09/2025

The World Directory of Crystallographers (WDC) offers an unparalleled compilation of expertise in the field. It’s free to join and open to all crystallographers and other scientists employing crystallographic methods. Add your name and be part of the mosaic: 🔗 www.iucr.org/people/wdc

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Reposted by Jon Agirre

Jon Agirre @glycojones.bsky.social · 03/09/2025

Just a few days left to register for the next Diamond/CCP4 Data Collection and Structure Solution Workshop! This is an excellent training course delivered at a unique location and close to the most wonderful time of the year. It also has LOTS of tutors per student! www.ccp4.ac.uk/schools/DLS-...

ccp4.ac.uk

DLS/CCP4 Workshop 2025

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Jon Agirre @glycojones.bsky.social · 03/09/2025

ccp4.ac.uk

DLS/CCP4 Workshop 2025

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Reposted by Jon Agirre

Krystle J McLaughlin @biophyskrys.bsky.social · 31/07/2025

Excited to share this story on the protein crystallography CURE I developed and have been teaching for the last 3 years! www.vassar.edu/news/student... This course is supported by my #CottrellScholars Award from RCSA. @rescorp.org @vassar.bsky.social #grantsinaction #biochemistry

Two scientists looking at a computer screen

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Reposted by Jon Agirre

Structural Biology Communications @actacrystf.iucr.org · 31/07/2025

We were pleased to publish some of the results from this course, some in our recent 'Empowering education through structural genomics' focused issue: journals.iucr.org/special_issu...

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Adam Sharp @adamcsharp.bsky.social · 29/07/2025

Happy World Rain Day! It’s raining… – Cats and dogs (English) – Old ladies and sticks (Welsh) – Like a pissing cow (French) – As from Esteri’s ass (Finnish) – Penguins headfirst (Uruguayan Spanish) – Pilot whales (Faroese) – Chair legs (Greek) – Wheelbarrows (Czech) – Men (hallelujah)

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Jon Agirre @glycojones.bsky.social · 27/07/2025

🏴󠁧󠁢󠁥󠁮󠁧󠁿🏴󠁧󠁢󠁥󠁮󠁧󠁿

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Jon Agirre @glycojones.bsky.social · 25/07/2025

AI chat bots behaving like science fiction AI chat bots because they were once trained on Asimov

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Reposted by Jon Agirre

Jon Agirre @glycojones.bsky.social · 18/07/2025

Just realised that we've been doing Interviews With Authors on YouTube for a whole year! I'd really appreciate receiving comments about these, e.g. suggest a structural biologist you would like us to interview Here's a playlist with all the videos we've done so far: www.youtube.com/playlist?lis...

youtube.com

Interviews with Authors - YouTube

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Reposted by Jon Agirre

IUCr2026 @iucr2026.bsky.social · 20/07/2025

Giddy up to Calgary! Stop by our #IUCr2026 booth at #ACA2025 to gear up for the 2026 Conference to get some Calgary Stampede merch, plan your trip, meet other attendees and more!

ACA2025 attendees wearing cowboy hats in front of a billboard that says "See you in Calgary!"

ACA2025 attendee wearing cowboy hat in front of a billboard that says "See you in Calgary!"

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Reposted by Jon Agirre

Paris Marx @parismarx.com · 19/07/2025

Fascinating. Microsoft emailed me to say it was raising the price of Microsoft 365, but when i went to cancel it offered me me the old price — without all the AI bullshit. It’s forcing AI on everyone and making them pay more for it, then only telling them they don’t have to if they try to cancel.

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Reposted by Jon Agirre

Nonia Pariente @npariente.bsky.social · 19/07/2025

Welcome to the new normal in Erurope Please use mosquito repellent

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Jon Agirre @glycojones.bsky.social · 18/07/2025

youtube.com

Interviews with Authors - YouTube

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Jon Agirre @glycojones.bsky.social · 14/07/2025

As the community gets ready for #ACA2025, we're proud to present this interview with @gabbygrowsxtals.bsky.social Vivian Stojanoff and @xtalmaker.bsky.social on how to prepare for successful protein crystallisation experiments! 🥳🥳 youtu.be/m34RI500OFU?...

youtu.be

Preparing for successful protein crystallization experiments

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

sarahejbowman @xtalmaker.bsky.social · 03/07/2025

Excited that our article made the cover of the July issue of @actacrystf.iucr.org! Congrats to my coauthors @gabbygrowsxtals.bsky.social & Vivian Stojanoff! Grateful for #NIH NIGMS R24 National Resource grant that enables workshops like the 2023 SAMPREP workshop @ @acastructuralsci.bsky.social

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Reposted by Jon Agirre

Gonzalo Parra @gonzaparra.bsky.social · 09/07/2025

🚨We've updated our preprint "Frustration, Dynamics, and Catalysis" ✨ We appreciate RT ☺️ A short 🧵1/8: We expanded the conceptual connection between the energy landscapes theory and catalysis, added new figures, and clarified how local frustration shapes enzyme function. arxiv.org/pdf/2505.00600

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Jon Agirre @glycojones.bsky.social · 08/07/2025

We’ve got some more ECR interviews coming — watch this space!

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Reposted by Jon Agirre

Randy Read 🇨🇦🇬🇧 @randyjread.bsky.social · 08/07/2025

More arguments for choosing society journals, where any profits are ploughed back into science! For structural biology, please consider @actacrystd.iucr.org, @actacrystf.iucr.org and @iucrj.iucr.org!

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Jon Agirre @glycojones.bsky.social · 06/07/2025

Together with Toyin Asojo, Graham Chakafana and Craig Smith, we have recently edited a focused issue on 'Empowering education through structural genomics', featuring the work of both undergrads and high school students – watch Toyin interview Aruesha, Aryana & Raymond www.youtube.com/watch?v=KJkN...

youtube.com

Structures of Trichomonas vaginalis macrophage migratory inhibitory factor

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 06/07/2025

youtube.com

Structures of Trichomonas vaginalis macrophage migratory inhibitory factor

YouTube video by International Union of Crystallography

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Reposted by Jon Agirre

Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 02/07/2025

The dependence of the amino acid backbone conformation on the translated synonymous codon is not statistically significant doi.org/10.1073/pnas... [Following: Codon-specific Ramachandran plots show amino acid backbone conformation depends on identity of the translated codon doi.org/10.1038/s414...

doi.org

The dependence of the amino acid backbone conformation on the translated synonymous codon is not statistically significant | PNAS

The correlation between synonymous codon usage and secondary structure in translated proteins has been widely demonstrated. This usage plays a capi...

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Mike Glazer @glazer1.bsky.social · 19/06/2025

Whether you're just starting out or well established in your field, adding your name helps build visibility, collaboration and community. Join the World Directory of Crystallographers. It's free! Sign up today and connect with peers worldwide: www.iucr.org/people/wdc

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Reposted by Jon Agirre

Chris Ashwood @cashwood.proteaglyco.com · 10/06/2025

By deep characterisation of 186 N-glycan standards, we @thencfg.bsky.social have made the most comprehensive targeted LC-MS glycomic assay to date. Non-reduced native glycan analysis is key. We hope this enables anyone with QqQ and interest in #glycotime to measure specific N-glycan structures.

186 pure glycan structures used to construct a targeted glycomic assay

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Tanmay Bharat @tbharat-lab.bsky.social · 05/06/2025

Incredibly grateful to my mentors, lab members, and generous collaborators who continue to inspire our work. Thankful also to microbial cell surfaces and tomography, which continue to deliver the excitement everyday!

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Structural Biology @actacrystd.iucr.org · 06/06/2025

Edited by Tom Burnley, Paula da Fonseca, Vicki Gold and Stephen Muench, this Structural Biology – Acta Cryst. D virtual issue collects articles from the 2023 CCP-EM Spring Symposium, showcasing recent advances in cryo-EM and structural biology methods. tinyurl.com/22evpux5

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Jon Agirre @glycojones.bsky.social · 23/05/2025

Happy to introduce our latest interview, where Cristy Nonato and I chat to Raphael Meneghello, Andrey Nascimento and Daniela Trivella about their research on natural product-based drug discovery, which they've carried out at the SIRIUS synchrotron in Brazil. www.youtube.com/watch?v=xQGq...

youtube.com

Protein crystallography to empower natural product-based drug discovery

YouTube video by International Union of Crystallography

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Jon Agirre @glycojones.bsky.social · 23/05/2025

youtube.com

Protein crystallography to empower natural product-based drug discovery

YouTube video by International Union of Crystallography

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