Abstract. Haem-regulated inhibitor (HRI) is emerging as a potential therapeutic target in several disease areas, including cancers such as multiple myeloma and neurodegenerative disease. As one of fou...

Funder’s quiet introduction of randomisation option across opportunities prompts questions, plus support for “innovative” action

Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS) is an established tool in drug discovery, used to characterize target engagement and conformational dynamics, and frequently used in both biophar...

Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

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Closing date: Wednesday 18 February 2026, 23:59

PhD Project - Exploring Resistance to KRAS inhibitors (KRASi) of differentiated Mechanism of Action at Babraham Institute (Cambridge), listed on FindAPhD.com

Ellie Chan traces the story of a set of unique and puzzling manuscripts

Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...

Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) is an established tool in drug discovery, used to characterize target engagement and conformational dynamics, frequently used in both biopharmace...