iiinova — where your digital self keeps evolving

Reposted by petar glažar

Cledi Cerda-Jara @cledicj.bsky.social · 28/04/2026

🚨 Our new review is out! What makes a circular RNA actually functional? We revisit Cdr1as/ciRS-7, one of the most studied circular RNAs, and bring together 15+ years of work to understand what makes it functionally unique. Check it out here 👇 www.nature.com/articles/s41...

nature.com

The history and function of a circular RNA - Nature Communications

In this paper, the authors review how the circular RNA Cdr1as and its interacting non-coding RNAs regulate neuronal stress responses and synaptic activity, highlighting general principles of RNA-based...

0105

Reposted by petar glažar

Tugce Aktas @aktast.bsky.social · 25/02/2026

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

doi.org

Redirecting

912561

Reposted by petar glažar

Juliane Glaser @julianeg.bsky.social · 04/09/2025

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development. We will have positions available next year. Stay tuned!

2514113

petar glažar @glazar.bsky.social · 18/07/2025

It's that time of the year - @mdc-berlin.bsky.social Pride Symposium in its 4th edition with great talks and discussions on intersectionality and DEI in general. As Neil Young said on Waldbuehne the other day - "Times are rough, we gotta look out for each other" 🫶 #MdcDiversity

0144

Reposted by petar glažar

Juliane Glaser @julianeg.bsky.social · 09/07/2025

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁 Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

nature.com

Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics

Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...

15296128

Reposted by petar glažar

Itai Yanai @itaiyanai.bsky.social · 16/06/2025

I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.

39616

Reposted by petar glažar

Petr Svoboda @svobodalab.bsky.social · 12/06/2025

#TCTeAC ... The Woodstock of Biology2 & Night Science was terminated by police arrival. >The End< Nobody apparently dared to take a picture but it's true.

5577

petar glažar @glazar.bsky.social · 12/06/2025

vibing with my gang on woodstock night science conference, day 3 #theconferencetoendallconferences #TCTeAC

091

Reposted by petar glažar

Oded Rechavi @odedrechavi.bsky.social · 11/06/2025

People at home following the Woodstock of Biology treads #theconferencetoendallconferences #TCTeAC

1234

Reposted by petar glažar

Henri Niskanen @henriniskanen.bsky.social · 04/06/2025

What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com ‬ with @yaotianzhang.bsky.social Denes Hnisz & team.

nature.com

2167

Reposted by petar glažar

Daniel Ibrahim @danielibrahim.bsky.social · 27/05/2025

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

rdcu.be

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances

Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

7247111

petar glažar @glazar.bsky.social · 08/05/2025

I think at this point I am moslty learning new biology from Jordi's memes 🔥🔥

010

petar glažar @glazar.bsky.social · 16/04/2025

Sequencing reads get longer, aligners get faster, LLMs get smarter, Katy Perry goes to space, but I still cannot type RNase without autocorrect making it weird.

040

Reposted by petar glažar

Tancredi M Pentimalli @tmpentimalli.bsky.social · 16/04/2025

Our 3D study of the tumor microenvironment is finally out! Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 ) Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!

25217

Reposted by petar glažar

Ines Patop @inespatop.bsky.social · 11/04/2025

And on other news. My first contribution to science as a postdoc with @stirlingchurchman.bsky.social is out! We discuss the knowns and unknowns of post-transcriptional splicing. It was really fun to write with the great @karinechoquet

23310