Somatic changes like copy number aberrations (CNAs) and epigenetic alterations like methylation have pivotal effects on disease outcomes and prognosis in cancer, by regulating gene expressions, that ...

Genetic Analysis Workshop 16 (GAW16) was held on September 17–20, 2008 in St. Louis, Missouri. The focus of GAW16 was on methods and challenges in analysis of single-nucleotide polymorphism data from...

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Comparison of association signals in UK Biobank using different strategies for assessing genetic variation shows that whole-exome sequencing combined with array genotyping and imputation offers simila...

Solving complex scientific problems related to how genetic variation influences disease . We’re a collaborative, international community of leaders in genetics, epidemiology...