Analysing the causal links of gene expression and protein abundance on type 2 diabetes risk in blood and seven tissues related to the disease from individuals of four ancestries, the authors advance our understanding of the genetic architecture of type 2 diabetes

Using tissue- and ancestry-aware causal inference analyses, we identified 923 genes and 46 proteins whose expression levels causally influence type 2 diabetes risk. Tissue-related heterogeneity was hi...

npj Metabolic Health and Disease - Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health

Evénement de vulgarisation scientifique grand public Science en Theizh organisé par l'association des doctorants brestois : Dakodoc

Human Genetics - The development of next-generation sequencing technologies has opened-up some new possibilities to explore the contribution of genetic variants to human diseases and in particular...